Barbara SELISKO

Curriculum vitae

 Ingénieur de Recherche groupe Dr. Bruno Canard (IR2 Aix Marseille Université)
 Responsable opérationnelle plateforme de criblage Marseille-Luminy

Sujet de recherche : Etudes d’activité et d’inhibition de réplicase virales

Expérience :

• 1990 Doctorat en biochimie Martin-Luther-Universität Halle/Allemagne
• 1991 PostDoc Humboldt-Universität Berlin/Allemagne
• 1992 à 1993 PostDoc University of London/Royaumes Unis financé par le British Council et l’Office Allemand d’échanges Universitaires)
• 1994 à 2000 PostDoc Universidad National Autonoma de Mexico financé en partie par la Fondation Humboldt Allemagne
• Depuis 2001 AFMB Marseille

DERNIERES PUBLICATIONS

1. 3',5'Di-O-trityluridine inhibits in vitro flavivirus replication. (2013)
   De Burghgraeve T, Selisko B , Kaptein S, Chatelain G, Leyssen P, Debing Y, Jacobs M, Van Aerschot A, Canard B, Neyts J
   Antiviral Res 98(2) 242-7
2. Nuclear localization of dengue virus nonstructural protein 5 does not strictly correlate with efficient viral RNA replication and inhibition of type I interferon signaling. (2013)
   Kumar A, Buhler S, Selisko B , Davidson A, Mulder K, Canard B, Miller S, Bartenschlager R
   J Virol 87 4545-57
3. The viral RNA capping machinery as a target for antiviral drugs. (2012)
   Ferron F, Decroly E, Selisko B , Canard B
   Antiviral Res 96 21-31
4. Molecular basis for nucleotide conservation at the ends of the dengue virus genome. (2012)
   Selisko B , Potisopon S, Agred R, Priet S, Varlet I, Thillier Y, Sallamand C, Debart F, Vasseur JJ, Canard B
   PLoS Pathog 8 e1002912
5. [Capping strategies in RNA viruses.] (2012)
   Bouvet M, Ferron F, Imbert I, Gluais L, Selisko B , Coutard B, Canard B, Decroly E
   Med Sci (Paris) 28 423-429
6. Picornavirus non-structural proteins as targets for new anti-virals with broad activity. (2011)
   Norder H, De Palma AM, Selisko B , Costenaro L, Papageorgiou N, Arnan C, Coutard B, Lantez V, De Lamballerie X, Baronti C, Sola M, Tan J, Neyts J, Canard B, Coll M, Gorbalenya AE, Hilgenfeld R
   Antiviral Res 89(3) 204-218
7. Structure and Functionality in Flavivirus Ns-Proteins: Perspectives for Drug Design. (2010)
   Bollati M, Alvarez K, Assenberg R, Baronti C, Canard B, Cook S, Coutard B, Decroly E, De Lambellerie X, Gould EA, Grard G, Grimes JM, Hilgenfeld R, Jansson AM, Malet H, Mancini EJ, Mastrangelo E, Mattevi A, Milani M, Moureau G, Neyts J, Owens RJ, Ren J, Selisko B , Speroni S, Steuber H, Stuart DI, Unge T, Bolognesi M
   Antiviral Res 87(2) 125-48
8. In vitro reconstitution of SARS-coronavirus mRNA cap methylation. (2010)
   Bouvet M, Debarnot C, Imbert I, Selisko B , Snijder EJ, Canard B, Decroly E
   PLoS Pathog 6 e1000863
9. Biochemical characterization of the (nucleoside-2\'O)-methyltransferase activity of dengue virus protein NS5 using purified capped RNA oligonucleotides 7MeGpppACn and GpppACn. (2010)
   Selisko B , Peyrane FF, Canard B, Alvarez K, Decroly E
   J Gen Virol 91 112-21
10. Recognition of RNA Cap in the Wesselsbron Virus NS5 Methyltransferase Domain: Implications for RNA-Capping Mechanisms in Flavivirus. (2009)
    Bollati M, Milani M, Mastrangelo E, Ricagno S, Tedeschi G, Nonnis S, Decroly E, Selisko B , de Lamballerie X, Coutard B, Canard B, Bolognesi M
    J Mol Biol 385 140-52