Team’s publications

2021

1. A High-Affinity Peptide Ligand Targeting Syntenin Inhibits Glioblastoma (2021)
   Haugaard-Kedstrom LM, Clemmensen LS, Sereikaite V, Jin Z, Fernandes EFA, Wind B, Abalde-Gil F, Daberger J, Vistrup-Parry M, Aguilar-Morante D, Leblanc R, Egea-Jimenez AL, Albrigtsen M, Jensen KE, Jensen TMT, Ivarsson Y, Vincentelli R, Hamerlik P, Andersen JH, Zimmermann P, Lee W, Stromgaard K.
   J Med Chem 64 1423-1434 PMID:33502198
2. Capping pores of alphavirus nsP1 gate membranous viral replication factories (2021)
   Jones R, Bragagnolo G, Arranz R, Reguera J.
   Nature 589 615-619 PMID:33328629

2020

3. Interactomic affinity profiling by holdup assay: Acetylation and distal residues impact the PDZome-binding specificity of PTEN phosphatase (2020)
   Jane P, Gogl G, Kostmann C, Bich G, Girault V, Caillet-Saguy C, Eberling P, Vincentelli R, Wolff N, Trave G, Nomine Y.
   PLoS One 15 e0244613 PMID:33382810
4. Dual Specificity PDZ- and 14-3-3-Binding Motifs: A Structural and Interactomics Study (2020)
   Gogl G, Jane P, Caillet-Saguy C, Kostmann C, Bich G, Cousido-Siah A, Nyitray L, Vincentelli R, Wolff N, Nomine Y, Sluchanko NN, Trave G.
   Structure 28 747-759.e3 PMID:32294469
5. A Venomics Approach Coupled to High-Throughput Toxin Production Strategies Identifies the First Venom-Derived Melanocortin Receptor Agonists (2020)
   Reynaud S, Ciolek J, Degueldre M, Saez NJ, Sequeira AF, Duhoo Y, Bras JLA, Meudal H, Cabo Diez M, Fernandez Pedrosa V, Verdenaud M, Boeri J, Pereira Ramos O, Ducancel F, Vanden Driessche M, Fourmy R, Violette A, Upert G, Mourier G, Beck-Sickinger AG, Morl K, Landon C, Fontes CMGA, Minambres Herraiz R, Rodriguez de la Vega RC, Peigneur S, Tytgat J, Quinton L, De Pauw E, Vincentelli R, Servent D, Gilles N.
   J Med Chem 63 8250-8264 PMID:32602722
6. Pre-initiation and elongation structures of full-length La Crosse virus polymerase reveal functionally important conformational changes (2020)
   Arragain B, Effantin G, Gerlach P, Reguera J, Schoehn G, Cusack S, Malet H.
   Nat Commun 11 3590 PMID:32681014

2019

7. Structure and function of the Toscana virus cap-snatching endonuclease. (2019)
   Jones R, Lessoued S, Meier K, Devignot S, Barata-Garcia S, Mate M, Bragagnolo G, Weber F, Rosenthal M, Reguera J.
   Nucleic Acids Res 47 10914-10930 PMID:31584100
8. The fungal ribonuclease-like effector protein CSEP0064/BEC1054 represses plant immunity and interferes with degradation of host ribosomal RNA. (2019)
   Pennington HG, Jones R, Kwon S, Bonciani G, Thieron H, Chandler T, Luong P, Morgan SN, Przydacz M, Bozkurt T, Bowden S, Craze M, Wallington EJ, Garnett J, Kwaaitaal M, Panstruga R, Cota E, Spanu PD.
   PLoS Pathog 15 e1007620 PMID:30856238
9. Structure-based optimization of a PDZ-binding motif within a viral peptide stimulates neurite outgrowth. (2019)
   Khan Z, Terrien E, Delhommel F, Lefebvre-Omar C, Bohl D, Vitry S, Bernard C, Ramirez J, Chaffotte A, Ricquier K, Vincentelli R, Buc H, Prehaud C, Wolff N, Lafon M.
   J Biol Chem 294 13755-13768 PMID:31346033
10. High-Throughput Production of a New Library of Human Single and Tandem PDZ Domains Allows Quantitative PDZ-Peptide Interaction Screening Through High-Throughput Holdup Assay. (2019)
    Duhoo Y, Girault V, Turchetto J, Ramond L, Durbesson F, Fourquet P, Nomine Y, Cardoso V, Sequeira AF, Bras JLA, Fontes CMGA, Trave G, Wolff N, Vincentelli R.
    Methods Mol Biol 2025 439-476 PMID:31267466
11. High-Throughput Production of Oxidized Animal Toxins in Escherichia coli. (2019)
    Duhoo Y, Sequeira AF, Saez NJ, Turchetto J, Ramond L, Peysson F, Bras JLA, Gilles N, Darbon H, Fontes CMGA, Vincentelli R.
    Methods Mol Biol 2025 165-190 PMID:31267452
12. Sizes of actin networks sharing a common environment are determined by the relative rates of assembly. (2019)
    Antkowiak A, Guillotin A, Boiero Sanders M, Colombo J, Vincentelli R, Michelot A.
    PLoS Biol 17 e3000317 PMID:31181075
13. High resolution cryo-EM structure of the helical RNA-bound Hantaan virus nucleocapsid reveals its assembly mechanisms. (2019)
    Arragain B, Reguera J, Desfosses A, Gutsche I, Schoehn G, Malet H.
    Elife 8 e43075 PMID:30638449
14. Discovery of novel carbohydrate-active enzymes through the rational exploration of the protein sequences space. (2019)
    Helbert W, Poulet L, Drouillard S, Mathieu S, Loiodice M, Couturier M, Lombard V, Terrapon N, Turchetto J, Vincentelli R, Henrissat B.
    Proc Natl Acad Sci U S A 116 6063-6068 PMID:30850540
15. Rewiring of RSK-PDZ Interactome by Linear Motif Phosphorylation. (2019)
    Gogl G, Biri-Kovacs B, Durbesson F, Jane P, Nomine Y, Kostmann C, Bilics V, Simon M, Remenyi A, Vincentelli R, Trave G, Nyitray L.
    J Mol Biol 431 1234-1249 PMID:30726710

2018

16. A gated relaxation oscillator mediated by FrzX controls morphogenetic movements in Myxococcus xanthus. (2018)
    Guzzo M, Murray SM, Martineau E, Lhospice S, Baronian G, My L, Zhang Y, Espinosa L, Vincentelli R, Bratton BP, Shaevitz JW, Molle V, Howard M, Mignot T.
    Nat Microbiol 3 948-959 PMID:30013238

2017

17. Transcription and replication mechanisms of Bunyaviridae and Arenaviridae L proteins. (2017)
    Ferron F, Weber F, de la Torre JC, Reguera J.
    Virus Res 234 118-134 PMID:28137457
18. Structural insights into reptarenavirus cap-snatching machinery. (2017)
    Rosenthal M, Gogrefe N, Vogel D, Reguera J, Rauschenberger B, Cusack S, Gunther S, Reindl S.
    PLoS Pathog 13 e1006400 PMID:28505175
19. Allosteric inhibition of aminopeptidase N functions related to tumor growth and virus infection. (2017)
    Santiago C, Mudgal G, Reguera J, Recacha R, Albrecht S, Enjuanes L, Casasnovas JM.
    Sci Rep 7 46045 PMID:28393915

2016

20. Towards a structural understanding of RNA synthesis by negative strand RNA viral polymerases. (2016)
    Reguera J, Gerlach P, Cusack S.
    Curr Opin Struct Biol 36 75-84 PMID:26826467
21. Comparative Structural and Functional Analysis of Bunyavirus and Arenavirus Cap-Snatching Endonucleases. (2016)
    Reguera J, Gerlach P, Rosenthal M, Gaudon S, Coscia F, Gunther S, Cusack S.
    PLoS Pathog 12 e1005636 PMID:27304209
22. Atomic Structure and Biochemical Characterization of an RNA Endonuclease in the N Terminus of Andes Virus L Protein. (2016)
    Fernandez-Garcia Y, Reguera J, Busch C, Witte G, Sanchez-Ramos O, Betzel C, Cusack S, Gunther S, Reindl S.
    PLoS Pathog 12 e1005635 PMID:27300328

2015

23. Structural Insights into Bunyavirus Replication and Its Regulation by the vRNA Promoter. (2015)
    Gerlach P, Malet H, Cusack S, Reguera J.
    Cell 161 1267-79 PMID:26004069