The CAZy bioinformatics

This platform is based on the bioinformatics tools and curation efforts associated to the CAZy database (www.cazy.org), updated by the glycogenomics team since its launch in September 1998. The platform performs the analysis of genomes and metagenomic datasets in order to identify the encoded enzymes for the assembly and breakdown of complex carbohydrates. The enzymes currently covered in our analyses include the glycoside hydrolases, the glycosyltransferases, polysaccharide lyases, carbohydrate esterases, and auxiliary redox proteins such as lytic polysaccharide mono-oxygenases).

Access to

Academics and private companies

Contact

Bernard Henrissat

Specific Equipement

1 HPC with 360 cores, 1 HPC with 64 cores, 4 SMP computers with 64 cores, 2 computers with 8 cores

Cost

Private companies: to be discussed (based on data volume, computer time required and human resources implicated). Academics: collaboration basis.

Examples of publications that made use of our platform

Seedorf et al. (2014) Bacteria from diverse habitats colonize and compete in the mouse gut. Cell 159, 1-14
Ridaura et al. (2013) Gut microbiota from twins discordant for obesity modulate metabolism in mice. Science 341:1241214.
Floudas et al. (2012) The Paleozoic origin of white rot wood decay reconstructed using 31 fungal genomes. Science 336, 1715-1719
Ohm et al. (2012) Diverse lifestyles and strategies of plant pathogenesis encoded in the genomes of eighteen Dothideomycetes fungi. PLoS Pathogens 8(12): e1003037
Muegge et al. (2011) Diet drives convergence in gut microbiome functions across mammalian phylogeny and within humans. Science 332, 970-974