Les publications de l’équipe

Responsables Alain ROUSSEL, Christian CAMBILLAU

2017

Type VI secretion TssK baseplate protein exhibits structural similarity with phage receptor-binding proteins and evolved to bind the membrane complex. (2017)

Nguyen VS, Logger L, Spinelli S, Legrand P, Huyen Pham TT, Nhung Trinh TT, Cherrak Y, Zoued A, Desmyter A, Durand E, Roussel A, Kellenberger C, Cascales E, Cambillau C.

Nat Microbiol 2 17103 PMID:28650463
Camelid nanobodies used as crystallization chaperones for different constructs of PorM, a component of the type IX secretion system from Porphyromonas gingivalis. (2017)

Duhoo Y, Roche J, Trinh TTN, Desmyter A, Gaubert A, Kellenberger C, Cambillau C, Roussel A, Leone P.

Acta Crystallogr F Struct Biol Commun 73 286-293 PMID:28471361
Genetic and functional characterisation of the lactococcal P335 phage-host interactions. (2017)

Mahony J, Oliveira J, Collins B, Hanemaaijer L, Lugli GA, Neve H, Ventura M, Kouwen TR, Cambillau C, van Sinderen D.

BMC Genomics 18 146 PMID:28183268
Evolved distal tail carbohydrate binding modules of Lactobacillus phage J-1: a novel type of anti-receptor widespread among lactic acid bacteria phages. (2017)

Dieterle ME, Spinelli S, Sadovskaya I, Piuri M, Cambillau C.

Mol Microbiol in press PMID:28196397
Characterization of the Porphyromonas gingivalis Type IX Secretion Trans-Envelope PorKLMNP Core Complex. (2017)

Vincent MS, Canestrari MJ, Leone P, Stathopoulos J, Ize B, Zoued A, Cambillau C, Kellenberger C, Roussel A, Cascales E.

J Biol Chem 292 3252-3261 PMID:28057754
Probing Conformational Changes and Interfacial Recognition Site of Lipases With Surfactants and Inhibitors. (2017)

Mateos-Diaz E, Amara S, Roussel A, Longhi S, Cambillau C, Carriere F.

Methods Enzymol 583 279-307 PMID:28063495
High-throughput expression of animal venom toxins in Escherichia coli to generate a large library of oxidized disulphide-reticulated peptides for drug discovery. (2017)

Turchetto J*, Sequeira AF*, Ramond L*, Peysson F*, Bras JL, Saez NJ, Duhoo Y, Blemont M, Guerreiro CI, Quinton L, De Pauw E, Gilles N, Darbon H, Fontes CM, Vincentelli R.

Microb Cell Fact 16 6 PMID:28095880
Gene design, fusion technology and TEV cleavage conditions influence the purification of oxidized disulphide-rich venom peptides in Escherichia coli. (2017)

Sequeira AF*, Turchetto J*, Saez NJ, Peysson F, Ramond L, Duhoo Y, Blemont M, Fernandes VO, Gama LT, Ferreira LM, Guerreiro CI, Gilles N, Darbon H, Fontes CM, Vincentelli R.

Microb Cell Fact 16 4 PMID:28093085

2016

Functional and structural dissection of the tape measure protein of lactococcal phage TP901-1. (2016)

Mahony J, Alqarni M, Stockdale S, Spinelli S, Feyereisen M, Cambillau C, Sinderen DV.

Sci Rep 6 36667 PMID:27824135
Sialylated Fetuin-A as a candidate predictive biomarker for successful grass pollen allergen immunotherapy. (2016)

Caillot N, Bouley J, Jain K, Mariano S, Luce S, Horiot S, Airouche S, Beuraud C, Beauvallet C, Devillier P, Chollet-Martin S, Kellenberger C, Mascarell L, Chabre H, Batard T, Nony E, Lombardi V, Baron-Bodo V, Moingeon P.

J Allergy Clin Immunol in press PMID:27965111
Inhibitors and Antibody Fragments as Potential Anti-Inflammatory Therapeutics Targeting Neutrophil Proteinase 3 in Human Disease. (2016)

Korkmaz B, Lesner A, Guarino C, Wysocka M, Kellenberger C, Watier H, Specks U, Gauthier F, Jenne DE.

Pharmacol Rev 68 603-30 PMID:27329045
Development of a gene synthesis platform for the efficient large scale production of small genes encoding animal toxins. (2016)

Sequeira AF, Bras JL, Guerreiro CI, Vincentelli R, Fontes CM.

BMC Biotechnol 16 86 PMID:27905914
T7 Endonuclease I Mediates Error Correction in Artificial Gene Synthesis. (2016)

Sequeira AF, Guerreiro CI, Vincentelli R, Fontes CM.

Mol Biotechnol 58 573-84 PMID:27334914
Differential conformational modulations of MreB folding upon interactions with GroEL/ES and TRiC chaperonin components. (2016)

Moparthi SB, Carlsson U, Vincentelli R, Jonsson BH, Hammarstrom P, Wenger J.

Sci Rep 6 28386 PMID:27328749
How disordered is my protein and what is its disorder for? A guide through the dark side of the protein universe. (2016)

Lieutaud P, Ferron F, Uversky AV, Kurgan L, Uversky VN and Longhi S..

Intrinsically Disordered Proteins 4:1 e1259708 PMID:0
Structure and specificity of the Type VI secretion system ClpV-TssC interaction in enteroaggregative Escherichia coli. (2016)

Douzi B, Brunet YR, Spinelli S, Lensi V, Legrand P, Blangy S, Kumar A, Journet L, Cascales E, Cambillau C.

Sci Rep 6 34405 PMID:27698444
Structure-function analysis of the TssL cytoplasmic domain reveals a new interaction between the Type VI secretion baseplate and membrane complexes. (2016)

Zoued A, Cassaro CJ, Durand E, Douzi B, Espana AP, Cambillau C, Journet L, Cascales E.

J Mol Biol 428 4413-4423 PMID:27600409
Characterization of prophages containing "evolved" Dit/Tal modules in the genome of Lactobacillus casei BL23. (2016)

Dieterle ME, Fina Martin J, Duran R, Nemirovsky SI, Sanchez Rivas C, Bowman C, Russell D, Hatfull GF, Cambillau C, Piuri M.

Appl Microbiol Biotechnol 100 9201-9215 PMID:27448399
Structure of the host-recognition device of Staphylococcus aureus phage varphi11. (2016)

Koc C, Xia G, Kuhner P, Spinelli S, Roussel A, Cambillau C, Stehle T.

Sci Rep 6 27581 PMID:27282779
The baseplate of Lactobacillus delbrueckii bacteriophage Ld17 harbours a glycerophosphodiesterase. (2016)

Cornelissen A, Sadovskaya I, Vinogradov E, Blangy S, Spinelli S, Casey E, Mahony J, Noben JP, Dal Bello F, Cambillau C, van Sinderen D.

J Biol Chem 291 16816-27 PMID:27268053
An essential role for the baseplate protein Gp45 in phage adsorption to Staphylococcus aureus. (2016)

Li X, Koc C, Kuhner P, Stierhof YD, Krismer B, Enright MC, Penades JR, Wolz C, Stehle T, Cambillau C, Peschel A, Xia G.

Sci Rep 6 26455 PMID:27212064
phage TP901-1 as a model for virion assembly. (2016)

Mahony J, Stockdale SR, Collins B, Spinelli S, Douillard FP, Cambillau C, van Sinderen D.

Bacteriophage 6 e1123795 PMID:27144086
Complex Reconstitution and Characterization by Combining Co-expression Techniques in Escherichia coli with High-Throughput. (2016)

Vincentelli R, Romier C.

Adv Exp Med Biol 896 43-58 PMID:27165318
In cellulo phosphorylation induces pharmacological reprogramming of maurocalcin, a cell-penetrating venom peptide. (2016)

Ronjat M, Feng W, Dardevet L, Dong Y, Al Khoury S, Chatelain FC, Vialla V, Chahboun S, Lesage F, Darbon H, Pessah IN, De Waard M..

Proc Natl Acad Sci U S A 113 E2460-8 PMID:27071086
Structural mimicry of receptor interaction by antagonistic IL-6 antibodies. (2016)

Blanchetot C, de Jonge N, Desmyter A, Ongenae N, Hofman E, Klarenbeek A, Sadi A, Hultberg A, Kretz-Rommel A, Spinelli S, Loris R, Cambillau C, de Haard H.

J Biol Chem 291 13846-54 PMID:27129274
Combining somatic mutations present in different in vivo affinity-matured antibodies isolated from immunized Lama glama yields ultra-potent antibody therapeutics. (2016)

Klarenbeek A, Blanchetot C, Schragel G, Sadi AS, Ongenae N, Hemrika W, Wijdenes J, Spinelli S, Desmyter A, Cambillau C, Hultberg A, Kretz-Rommel A, Dreier T, De Haard HJ, Roovers RC.

Protein Eng Des Sel 29 123-33 PMID:26945588
Priming and polymerization of a bacterial contractile tail structure. (2016)

Zoued A, Durand E, Brunet YR, Spinelli S, Douzi B, Guzzo M, Flaugnatti N, Legrand P, Journet L, Fronzes R, Mignot T, Cambillau C, Cascales E.

Nature 531 59-63 PMID:26909579
The Atomic Structure of the Phage Tuc2009 Baseplate Tripod Suggests that Host Recognition Involves Two Different Carbohydrate Binding Modules. (2016)

Legrand P, Collins B, Blangy S, Murphy J, Spinelli S, Gutierrez C, Richet N, Kellenberger C, Desmyter A, Mahony J, van Sinderen D, Cambillau C.

MBio 7 e01781-15 PMID:26814179
Cytokine Diedel and a viral homologue suppress the IMD pathway in Drosophila. (2016)

Lamiable O, Kellenberger C, Kemp C, Troxler L, Pelte N, Boutros M, Marques JT, Daeffler L, Hoffmann JA, Roussel A, Imler JL.

Proc Natl Acad Sci U S A 113 698-703 PMID:26739560
A phospholipase A anti-bacterial T6SS effector interacts directly with the C-terminal domain of the VgrG spike protein for delivery. (2016)

Flaugnatti N, Le TT, Canaan S, Aschtgen MS, Nguyen VS, Blangy S, Kellenberger C, Roussel A, Cambillau C, Cascales E, Journet L.

Mol Microbiol 99 1099-1118 PMID:26714038
Tissue-Specific Regulation of Drosophila NF-kB Pathway Activation by Peptidoglycan Recognition Protein SC. (2016)

Costechareyre D, Capo F, Fabre A, Chaduli D, Kellenberger C, Roussel A, Charroux B, Royet J.

J Innate Immun 8 67-80 PMID:26513145

2015

Quantifying domain-ligand affinities and specificities by high-throughput holdup assay. (2015)

Vincentelli R, Luck K, Poirson J, Polanowska J, Abdat J, Blemont M, Turchetto J, Iv F, Ricquier K, Straub ML, Forster A, Cassonnet P, Borg JP, Jacob Y, Masson M, Nomine Y, Reboul J, Wolff N, Charbonnier S, Trave G.

Nat Methods 12 787-93 PMID:26053890
Development and evaluation of a sublingual tablet based on recombinant Bet v 1 in birch pollen-allergic patients. (2015)

Nony E, Bouley J, Le Mignon M, Lemoine P, Jain K, Horiot S, Mascarell L, Pallardy M, Vincentelli R, Leone P, Roussel A, Batard T, Abiteboul K, Robin B, de Beaumont O, Arvidsson M, Rak S, Moingeon P.

Allergy 70 795-804 PMID:25846209
RNA 1 and RNA 2 Genomic Segments of Chronic Bee Paralysis Virus Are Infectious and Induce Chronic Bee Paralysis Disease (2015)

Youssef I, Schurr F, Goulet A, Cougoule N, Ribiere-Chabert M, Darbon H, Thiery R, Dubois E.

J Immunol Res 2015 423493 PMID:26583154
The Type VI Secretion TssEFGK-VgrG Phage-Like Baseplate Is Recruited to the TssJLM Membrane Complex via Multiple Contacts and Serves As Assembly Platform for Tail Tube/Sheath Polymerization. (2015)

Brunet YR, Zoued A, Boyer F, Douzi B, Cascales E.

PLoS Genet 11 e1005545 PMID:26460929
Structure and Assembly of TP901-1 Virion Unveiled by Mutagenesis. (2015)

Stockdale SR, Collins B, Spinelli S, Douillard FP, Mahony J, Cambillau C, van Sinderen D.

PLoS One 10 e0131676 PMID:26147978
Biogenesis and structure of a type VI secretion membrane core complex. (2015)

Durand E, Nguyen VS, Zoued A, Logger L, Pehau-Arnaudet G, Aschtgen MS, Spinelli S, Desmyter A, Bardiaux B, Dujeancourt A, Roussel A, Cambillau C, Cascales E, Fronzes R.

Nature 523 555-560 PMID:26200339
Bacteriophage module reshuffling results in adaptive host range as exemplified by the baseplate model of listerial phage A118. (2015)

Cambillau C.

Virology 484 86-92 PMID:26074066
Camelid Ig V genes reveal significant human homology not seen in therapeutic target genes, providing for a powerful therapeutic antibody platform. (2015)

Klarenbeek A, El Mazouari K, Desmyter A, Blanchetot C, Hultberg A, de Jonge N, Roovers RC, Cambillau C, Spinelli S, Del-Favero J, Verrips T, de Haard HJ, Achour I.

MAbs 7 693-706 PMID:26018625
X-ray and Cryo-electron Microscopy Structures of Monalysin Pore Forming Toxin Reveals Multimerization of the Pro-Form. (2015)

Leone P, Bebeacua C, Opota O, Kellenberger C, Klaholz B, Orlov I, Cambillau C, Lemaitre B, Roussel A.

J Biol Chem 290 13191-13201 PMID:25847242
Inhibition of Type VI Secretion by an Anti-TssM Llama Nanobody. (2015)

Nguyen VS, Logger L, Spinelli S, Desmyter A, Le TT, Kellenberger C, Douzi B, Durand E, Roussel A, Cascales E, Cambillau C.

PLoS One 10 e0122187 PMID:25811612
The targeted recognition of Lactococcus lactis phages to their polysaccharide receptors. (2015)

McCabe O, Spinelli S, Farenc C, Labbe M, Tremblay D, Blangy S, Oscarson S, Moineau S, Cambillau C.

Mol Microbiol 96 875-886 PMID:25708888
Production, crystallization and X-ray diffraction analysis of a complex between a fragment of the TssM T6SS protein and a camelid nanobody. (2015)

Nguyen VS, Spinelli S, Desmyter A, Le TT, Kellenberger C, Cascales E, Cambillau C, Roussel A.

Acta Crystallogr F Struct Biol Commun 71 266-71 PMID:25760699
Crystallization and preliminary X-ray analysis of the C-terminal fragment of PorM, a subunit of the Porphyromonas gingivalis type IX secretion system. (2015)

Stathopulos J, Cambillau C, Cascales E, Roussel A, Leone P.

Acta Crystallogr F Struct Biol Commun 71 71-4 PMID:25615973
Camelid nanobodies: killing two birds with one stone. (2015)

Desmyter A, Spinelli S, Roussel A, Cambillau C.

Curr Opin Struct Biol 32C 1-8 PMID:25614146
A Flexible Extension of the Drosophila Ultrabithorax Homeodomain Defines a Novel Hox/PBC Interaction Mode. (2015)

Foos N, Maurel-Zaffran C, Mate MJ, Vincentelli R, Hainaut M, Berenger H, Pradel J, Saurin AJ, Ortiz-Lombardia M, Graba Y.

Structure 23 270-279 PMID:25651060

2014

Generation of a vector suite for protein solubility screening. (2014)

Correa A, Ortega C, Obal G, Alzari P, Vincentelli R, Oppezzo P.

Front Microbiol 5 67 PMID:24616717
Bile-mediated activation of the acrAB and tolC multidrug efflux genes occurs mainly through transcriptional derepression of ramA in Salmonella enterica serovar Typhimurium. (2014)

Baucheron S, Nishino K, Monchaux I, Canepa S, Maurel MC, Coste F, Roussel A, Cloeckaert A, Giraud E.

J Antimicrob Chemother 69 2400-6 PMID:24816212
New selective peptidyl di(chlorophenyl) phosphonate esters for visualizing and blocking neutrophil proteinase 3 in human diseases. (2014)

Guarino C, Legowska M, Epinette C, Kellenberger C, Dallet-Choisy S, Sienczyk M, Gabant G, Cadene M, Zoidakis J, Vlahou A, Wysocka M, Marchand-Adam S, Jenne DE, Lesner A, Gauthier F, Korkmaz B.

J Biol Chem 289 31777-91 PMID:25288799
A Cutinase from Trichoderma reesei with a lid-covered active site and kinetic properties of true lipases. (2014)

Roussel A, Amara S, Nyyssola A, Mateos-Diaz E, Blangy S, Kontkanen H, Westerholm-Parvinen A, Carriere F, Cambillau C.

J Mol Biol 426 3757-72 PMID:25219509
Scribble1/AP2 Complex Coordinates NMDA Receptor Endocytic Recycling. (2014)

Piguel NH, Fievre S, Blanc JM, Carta M, Moreau MM, Moutin E, Pinheiro VL, Medina C, Ezan J, Lasvaux L, Loll F, Durand CM, Chang K, Petralia RS, Wenthold RJ, Stephenson FA, Vuillard L, Darbon H, Perroy J, Mulle C, Montcouquiol M, Racca C, Sans N..

Cell Rep 9 712-27 PMID:25310985
High throughput quantitative expression screening and purification applied to recombinant disulfide-rich venom proteins produced in E. coli. (2014)

Saez NJ, Nozach H, Blemont M, Vincentelli R.

J Vis Exp 89 e51464 PMID:25146501
X-ray structure of the mouse serotonin 5-HT3 receptor. (2014)

Hassaine G, Deluz C, Grasso L, Wyss R, Tol MB, Hovius R, Graff A, Stahlberg H, Tomizaki T, Desmyter A, Moreau C, Li XD, Poitevin F, Vogel H, Nury H.

Nature 512 276-81 PMID:25119048
CryoEM structure of the lactococcal siphophage 1358 virion. (2014)

Spinelli S, Bebeacua C, Orlov I, Tremblay D, Klaholz BP, Moineau S, Cambillau C.

J Virol 88 8900-8910 PMID:24872584
Differences in lactococcal cell wall polysaccharide structure are major determining factors in bacteriophage sensitivity. (2014)

Ainsworth S, Sadovskaya I, Vinogradov E, Courtin P, Guerardel Y, Mahony J, Grard T, Cambillau C, Chapot-Chartier MP, van Sinderen D.

MBio 5 e00880-14 PMID:24803515
Architecture and assembly of the Type VI secretion system. (2014)

Zoued A, Brunet YR, Durand E, Aschtgen MS, Logger L, Douzi B, Journet L, Cambillau C, Cascales E.

Biochim Biophys Acta 1843 1664-1673 PMID:24681160
Molecular insights on the recognition of a Lactococcus lactis cell wall pellicle by phage 1358 receptor binding protein. (2014)

Farenc C, Spinelli S, Vinogradov E, Tremblay D, Blangy S, Sadovskaya I, Moineau S, Cambillau C.

J Virol 88 7005-15 PMID:24719416
Crystal Structure and Self-Interaction of the Type VI Secretion Tail-Tube Protein from Enteroaggregative Escherichia coli. (2014)

Douzi B, Spinelli S, Blangy S, Roussel A, Durand E, Brunet YR, Cascales E, Cambillau C.

PLoS One 9 e86918 PMID:24551044
Structures and host-adhesion mechanisms of lactococcal siphophages. (2014)

Spinelli S, Veesler D, Bebeacua C, Cambillau C.

Front Microbiol 5 3 PMID:24474948

2013

Development of an ELISA detecting Tumor Protein 53-Induced Nuclear Protein 1 in serum of prostate cancer patients. (2013)

Saadi H, Seillier M, Sandi MJ, Peuget S, Kellenberger C, Gravis G, Dusetti NJ, Iovanna JL, Rocchi P, Amri M, Carrier A.

Results Immunol 3 51-6 PMID:24600558
Expression in Escherichia coli: becoming faster and more complex. (2013)

Vincentelli R, Romier C.

Curr Opin Struct Biol 23 326-34 PMID:23422067
DNA-binding specificities of human transcription factors. (2013)

Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J.

Cell 152 327-39 PMID:23332764
High throughput screening identifies disulfide isomerase DsbC as a very efficient partner for recombinant expression of small disulfide-rich proteins in E. coli. (2013)

Nozach H, Fruchart-Gaillard C, Fenaille F, Beau F, Ramos OH, Douzi B, Saez NJ, Moutiez M, Servent D, Gondry M, Thai R, Cuniasse P, Vincentelli R, Dive V.

Microb Cell Fact 12 37 PMID:23607455
A Toxin-Antitoxin Module of Promotes Virulence in Mice. (2013)

De la Cruz MA, Zhao W, Farenc C, Gimenez G, Raoult D, Cambillau C, Gorvel JP, Meresse S.

PLoS Pathog 9 e1003827 PMID:24385907
Molecular Engineering of Fungal GH5 and GH26 Beta-(1,4)-Mannanases toward Improvement of Enzyme Activity. (2013)

Couturier M, Feliu J, Bozonnet S, Roussel A, Berrin JG.

PLoS One 8 e79800 PMID:24278180
Dissection of the TssB-TssC Interface during Type VI Secretion Sheath Complex Formation. (2013)

Zhang XY, Brunet YR, Logger L, Douzi B, Cambillau C, Journet L, Cascales E.

PLoS One 8 e81074 PMID:24282569
Structure, Adsorption to Host, and Infection Mechanism of Virulent Lactococcal Phage p2. (2013)

Bebeacua C, Tremblay D, Farenc C, Chapot-Chartier MP, Sadovskaya I, van Heel M, Veesler D, Moineau S, Cambillau C.

J Virol 87 (22) 12302-12 PMID:24027307
TssK is a trimeric cytoplasmic protein interacting with components of both phage-like and membrane anchoring complexes of the Type VI secretion system. (2013)

Zoued A, Durand E, Bebeacua C, Brunet YR, Douzi B, Cambillau C, Cascales E, Journet L.

J Biol Chem 288 27031-41 PMID:23921384
Crystallization and preliminary X-ray analysis of monalysin, a novel beta-pore-forming toxin from the entomopathogen Pseudomonas entomophila. (2013)

Blemont M, Vincentelli R, Kellenberger C, Opota O, Lemaitre B, Roussel A, Leone P.

Acta Crystallogr Sect F Struct Biol Cryst Commun 69 930-933 PMID:23908046
Neutrophil proteinase 3 and dipeptidyl peptidase I (cathepsin C) as pharmacological targets in granulomatosis with polyangiitis (Wegener granulomatosis). (2013)

Korkmaz B, Lesner A, Letast S, Mahdi YK, Jourdan ML, Dallet-Choisy S, Marchand-Adam S, Kellenberger C, Viaud-Massuard MC, Jenne DE, Gauthier F.

Semin Immunopathol 35 411-21 PMID:23385856
The first structure of a mycobacteriophage, Araucaria. (2013)

Sassi M, Bebeacua C, Drancourt M, Cambillau C.

J Virol 87 8099-109 PMID:23678183
Structure and Functional analysis of the host-recognition device of Lactococcal Phage Tuc2009. (2013)

Collins B, Bebeacua C, Mahony J, Blangy S, Douillard FP, Veesler D, Cambillau C, van Sinderen D.

J Virol 87 8429-40 PMID:23698314
The DNA binding mechanism of a SSB protein from Lactococcus lactis siphophage p2. (2013)

Scaltriti E, Polverini E, Grolli S, Eufemi E, Moineau S, Cambillau C, Ramoni R.

Biochim Biophys Acta 1834 1070-76 PMID:23429182
X-ray structure of a superinfection exclusion lipoprotein from phage TP-J34 and identification of the tape measure protein as its target. (2013)

Bebeacua C, Lorenzo Fajardo JC, Blangy S, Spinelli S, Bollmann S, Neve H, Cambillau C, Heller KJ.

Mol Microbiol 89 152-65 PMID:23692331
Structural and biochemical analyses of glycoside hydrolase families 5 and 26 beta-(1,4)-mannanases from Podospora anserina reveal differences upon manno-oligosaccharides catalysis. (2013)

Couturier M, Roussel A, Rosengren A, Leone P, Stalbrand H, Berrin JG.

J Biol Chem 288 14624-35 PMID:23558681
Ligands for pheromone-sensing neurons are not conformationally activated odorant binding proteins. (2013)

Gomez-Diaz C, Reina JH, Cambillau C, Benton R.

PLoS Biol 11 e1001546 PMID:23637570
Selective inhibitors of human neutrophil proteinase 3. (2013)

Korkmaz B, Kellenberger C, Viaud-Massuard MC, Gauthier F.

Curr Pharm Des 19 966-76 PMID:23016687
Viral infection modulation and neutralization by camelid nanobodies. (2013)

Desmyter A, Farenc C, Mahony J, Spinelli S, Bebeacua C, Blangy S, Veesler D, van Sinderen D, Cambillau C.

Proc Natl Acad Sci U S A 110 E1371-9 PMID:23530214
Structure and activity of AbiQ, a lactococcal endoribonuclease belonging to the type-III toxin-antitoxin system. (2013)

Samson JE, Spinelli S, Cambillau C, Moineau S.

Mol Microbiol 87 756-68 PMID:23279123
Structure and function of AvtR, a novel transcriptional regulator from a hyperthermophilic archaeal lipothrixvirus. (2013)

Peixeiro N, Keller J, Collinet B, Leulliot N, Campanacci V, Cortez D, Cambillau C, Nitta KR, Vincentelli R, Forterre P, Prangishvili D, Sezonov G, van Tilbeurgh H.

J Virol 87 124-36 PMID:23055559
Visualizing a Complete Siphoviridae by Single-particle Electron Microscopy: The Structure of Lactococcal Phage TP901-1. (2013)

Bebeacua C, Lai L, Vegge CS, Brondsted L, van Heel M, Veesler D, Cambillau C.

J Virol 87 1061-8 PMID:23135714

2012

Tissue- and ligand-specific sensing of gram-negative infection in drosophila by PGRP-LC isoforms and PGRP-LE. (2012)

Neyen C, Poidevin M, Roussel A, Lemaitre B.

J Immunol 189 1886-97 PMID:22772451
Structural characterization and oligomerization of the TssL protein, a component shared by the bacterial Type VI and Type IVb secretion systems. (2012)

Durand E, Zoued A, Spinelli S, Watson PJ, Aschtgen MS, Journet L, Cambillau C, Cascales E.

J Biol Chem 287 14157-68 PMID:22371492
Involvement of the major capsid protein and two early-expressed phage genes in the activity of the lactococcal abortive infection mechanism AbiT. (2012)

Labrie SJ, Tremblay DM, Moisan M, Villion M, Magadan AH, Campanacci V, Cambillau C, Moineau S.

Appl Environ Microbiol 78 6890-9 PMID:22820334
Crystal structure of greglin, a novel non-classical Kazal inhibitor, in complex with subtilisin. (2012)

Derache C, Epinette C, Roussel A, Gabant G, Cadene M, Korkmaz B, Gauthier F, Kellenberger C.

FEBS J 279 4466-78 PMID:23075397
Structure of the phage TP901-1 1.8 MDa baseplate suggests an alternative host adhesion mechanism. (2012)

Veesler D, Spinelli S, Mahony J, Lichiere J, Blangy S, Bricogne G, Legrand P, Ortiz-Lombardia M, Campanacci V, van Sinderen D, Cambillau C.

Proc Natl Acad Sci U S A 109 8954-8958 PMID:22611190
Crystal Structure of ATV(ORF273), a New Fold for a Thermo- and Acido-Stable Protein from the Acidianus Two-Tailed Virus. (2012)

Felisberto-Rodrigues C, Blangy S, Goulet A, Vestergaard G, Cambillau C, Garrett RA, Ortiz-Lombardia M.

PLoS One 7 e45847 PMID:23056221
Crystal Structure of the VgrG1 Actin Cross-linking Domain of the Vibrio cholerae Type VI Secretion System. (2012)

Durand E, Derrez E, Audoly G, Spinelli S, Ortiz-Lombardia M, Raoult D, Cascales E, Cambillau C.

J Biol Chem 287 38190-9 PMID:22898822
Crystal structure of the DNA-bound VapBC2 antitoxin/toxin pair from Rickettsia felis. (2012)

Mate MJ, Vincentelli R, Foos N, Raoult D, Cambillau C, Ortiz-Lombardia M.

Nucleic Acids Res 40 3245-58 PMID:22140099
Crystal Structure of Diedel, a Marker of the Immune Response of Drosophila melanogaster. (2012)

Coste F, Kemp C, Bobezeau V, Hetru C, Kellenberger C, Imler JL, Roussel A.

PLoS One 7 e33416 PMID:22442689
Structural biology of type VI secretion systems. (2012)

Cascales E, Cambillau C.

Philos Trans R Soc Lond B Biol Sci 367 1102-11 PMID:22411981
Protein candidates for the serodiagnosis of rickettsioses. (2012)

Kowalczewska M, Vellaiswamy M, Nappez C, Vincentelli R, Scola BL, Raoult D.

FEMS Immunol Med Microbiol 64 130-3 PMID:22098357
Protein candidates for Q fever serodiagnosis. (2012)

Kowalczewska M, Nappez C, Vincentelli R, La Scola B, Raoult D.

FEMS Immunol Med Microbiol 64 140-2 PMID:22098576
A selective reversible azapeptide inhibitor of human neutrophil proteinase 3 derived from a high affinity FRET substrate. (2012)

Epinette C, Croix C, Jaquillard L, Marchand-Adam S, Kellenberger C, Lalmanach G, Cadene M, Viaud-Massuard MC, Gauthier F, Korkmaz B.

Biochem Pharmacol 83 788-96 PMID:22209715
Binding of the RamR repressor to wild-type and mutated promoters of the RamA gene involved in efflux-mediated multidrug resistance in Salmonella enterica serovar Typhimurium. (2012)

Baucheron S, Coste F, Canepa S, Maurel MC, Giraud E, Culard F, Castaing B, Roussel A, Cloeckaert A.

Antimicrob Agents Chemother 56 942-8 PMID:22123696
Crystal structure of Apis mellifera OBP14, a C-minus odorant-binding protein, and its complexes with odorant molecules. (2012)

Spinelli S, Lagarde A, Iovinella I, Legrand P, Tegoni M, Pelosi P, Cambillau C.

Insect Biochem Mol Biol 42 41-50 PMID:22075131

2011

The opening of the SPP1 bacteriophage tail, a prevalent mechanism in Gram-positive-infecting siphophages. (2011)

Goulet A, Lai-Kee-Him J, Veesler D, Auzat I, Robin G, Shepherd DA, Ashcroft AE, Richard E, Lichiere J, Tavares P, Cambillau C, Bron P.

J Biol Chem 286 25397-405 PMID:21622577
Characterization of rickettsial adhesin Adr2 belonging to a new group of adhesins in alpha-proteobacteria. (2011)

Vellaiswamy M, Kowalczewska M, Merhej V, Nappez C, Vincentelli R, Renesto P, Raoult D.

Microb Pathog 50 233-42 PMID:21288480
The active conformation of human glucokinase is not altered by allosteric activators. (2011)

Petit P, Antoine M, Ferry G, Boutin JA, Lagarde A, Gluais L, Vincentelli R, Vuillard L.

Acta Crystallogr D Biol Crystallogr 67 929-35 PMID:22101819
A substrate-based approach to convert SerpinB1 into a specific inhibitor of proteinase 3, the Wegener's granulomatosis autoantigen. (2011)

Jegot G, Derache C, Castella S, Lahouassa H, Pitois E, Jourdan ML, Remold-O'Donnell E, Kellenberger C, Gauthier F, Korkmaz B.

FASEB J 25 3019-31 PMID:21670065
Chaperone role for proteins p618 and p892 in the extracellular tail development of Acidianus two-tailed virus. (2011)

Scheele U, Erdmann S, Ungewickell EJ, Felisberto-Rodrigues C, Ortiz-Lombardia M, Garrett RA.

J Virol 85 4812-21 PMID:21367903
Towards a structural comprehension of bacterial type VI secretion systems: characterization of the TssJ-TssM complex of an Escherichia coli pathovar. (2011)

Felisberto-Rodrigues C, Durand E, Aschtgen MS, Blangy S, Ortiz-Lombardia M, Douzi B, Cambillau C, Cascales E.

PLoS Pathog 7 e1002386 PMID:22102820
Effect of rickettsial toxin VapC on its eukaryotic host. (2011)

Audoly G, Vincentelli R, Edouard S, Georgiades K, Mediannikov O, Gimenez G, Socolovschi C, Mege JL, Cambillau C, Raoult D.

PLoS One 6 e26528 PMID:22046301
Construction of two Lactococcus lactis expression vectors combining the Gateway and the NIsin Controlled Expression systems. (2011)

Douillard FP, Mahony J, Campanacci V, Cambillau C, van Sinderen D.

Plasmid 66 129-35 PMID:21807023
Deciphering the Xcp Pseudomonas aeruginosa type II secretion machinery through multiple interactions with substrates. (2011)

Douzi B, Ball G, Cambillau C, Tegoni M, Voulhoux R.

J Biol Chem 286 40792-801 PMID:21949187
The Crystal Structure of Odorant Binding Protein 7 from Anopheles gambiae Exhibits an Outstanding Adaptability of Its Binding Site. (2011)

Lagarde A, Spinelli S, Tegoni M, He X, Field L, Zhou JJ, Cambillau C.

J Mol Biol 414 401-12 PMID:22019737
Monalysin, a Novel ss-Pore-Forming Toxin from the Drosophila Pathogen Pseudomonas entomophila, Contributes to Host Intestinal Damage and Lethality. (2011)

Opota O, Vallet-Gely I, Vincentelli R, Kellenberger C, Iacovache I, Gonzalez MR, Roussel A, van der Goot FG, Lemaitre B.

PLoS Pathog 7 e1002259 PMID:21980286
Lactococcal Phage p2 ORF35-Sak3 is an ATPase involved in DNA recombination and AbiK mechanism. (2011)

Scaltriti E, Launay H, Genois MM, Bron P, Rivetti C, Grolli S, Ploquin M, Campanacci V, Tegoni M, Cambillau C, Moineau S, Masson JY.

Mol Microbiol 80 102-16 PMID:21276096
Structure-function analysis of grass clip serine protease involved in Drosophila toll pathway activation. (2011)

Kellenberger C, Leone P, Coquet L, Jouenne T, Reichhart JM, Roussel A.

J Biol Chem 286 12300-7 PMID:21310954
The Drosophila peptidoglycan-recognition protein LF interacts with peptidoglycan-recognition protein LC to downregulate the Imd pathway. (2011)

Basbous N, Coste F, Leone P, Vincentelli R, Royet J, Kellenberger C, Roussel A.

EMBO Rep 12 327-33 PMID:21372849
High-throughput protein expression screening and purification in Escherichia coli. (2011)

Vincentelli R, Cimino A, Geerlof A, Kubo A, Satou Y, Cambillau C.

Methods 55 65-72 PMID:21925268
The assembly mode of the pseudopilus: a hallmark to distinguish a novel secretion system subtype. (2011)

Durand E, Alphonse S, Brochier-Armanet C, Ball G, Douzi B, Filloux A, Bernard C, Voulhoux R.

J Biol Chem 286 24407-16 PMID:21586577
Structure of the minor pseudopilin XcpW from the Pseudomonas aeruginosa type II secretion system. (2011)

Franz LP, Douzi B, Durand E, Dyer DH, Voulhoux R, Forest KT.

Acta Crystallogr D Biol Crystallogr 67 124-30 PMID:21245534
A common evolutionary origin for tailed-bacteriophage functional modules and bacterial machineries. (2011)

Veesler D, Cambillau C.

Microbiol Mol Biol Rev 75 423-33 PMID:21885679
Expanding the molecular toolbox for Lactococcus lactis: construction of an inducible thioredoxin gene fusion expression system. (2011)

Douillard FP, O'Connell-Motherway M, Cambillau C, van Sinderen D.

Microb Cell Fact 10 66 PMID:21827702
Mycobacterium tuberculosis Rv1090 and Rv1987 encode functional b-glucan-targeting proteins (2011)

Mba Medie F, Vincentelli R, Drancourt M, Henrissat B.

Prot Express. Purif. 75 172-176 PMID:20826214

2010

Crystal structure of Bacillus subtilis SPP1 phage gp23.1, a putative chaperone. (2010)

Veesler D, Blangy S, Lichiere J, Ortiz-Lombardia M, Tavares P, Campanacci V, Cambillau C.

Protein Sci 19 1812-6 PMID:20665904
Characterization of antigens for Q fever serodiagnostics. (2010)

Sekeyova Z, Kowalczewska M, Vincentelli R, Decloquement P, Flores-Ramirez G, Skultety L, Raoult D.

Acta Virol 54 173-80 PMID:20822309
Structure and molecular assignment of lactococcal phage TP901-1 baseplate. (2010)

Bebeacua C, Bron P, Lai L, Vegge CS, Brondsted L, Spinelli S, Campanacci V, Veesler D, van Heel M, Cambillau C.

J Biol Chem 285 39079-86 PMID:20937834
Solution and electron microscopy characterization of lactococcal phage baseplates expressed in Escherichia coli. (2010)

Campanacci V, Veesler D, Lichiere J, Blangy S, Sciara G, Moineau S, van Sinderen D, Bron P, Cambillau C.

J Struct Biol 172(1) 75-84 PMID:20153432
D-maurocalcine, a pharmacologically-inert efficient cell penetrating peptide analogue. (2010)

Poillot C, Dridi K, Bichraoui H, Pecher J, Alphonse S, Douzi B, Ronjat M, Darbon H, De Waard M.

J Biol Chem 285(44) 34168-80 PMID:20610396
Crystal structure of bacteriophage SPP1 distal tail protein (GP 19.1): a baseplate hub paradigm in gram+ infecting phages. (2010)

Veesler D, Robin G, Lichiere J, Auzat I, Tavares P, Bron P, Campanacci V, Cambillau C.

J Biol Chem 285 36666-73 PMID:20843802
The lactococcal abortive infection protein AbiV interacts directly with the phage protein SaV and prevents translation of phage proteins. (2010)

Haaber J, Samson JE, Labrie SJ, Campanacci V, Cambillau C, Moineau S, Hammer K.

Appl Environ Microbiol 76(21) 7085-92 PMID:20851990
Solution structure of the C-terminal X domain of the Measles Virus Phosphoprotein and Interaction with the Intrinsically Disordered C-terminal Domain of the Nucleoprotein (2010)

Gely S, Lowry DF, Bernard C, Jensen MR, Blackledge M, Costanzo S, Bourhis JM, Darbon H, Daughdrill G, Longhi S.

J Mol Recognit 23 435-447 PMID:20058326
Spatial (Tbata) expression in mature medullary thymic epithelial cells. (2010)

Saade M, Irla M, Yammine M, Boulanger N, Victorero G, Vincentelli R, Penninger JM, Hollander GA, Chauvet S, Nguyen C.

Eur J Immunol 40 530-8 PMID:19918778
Structural Disorder within Henipavirus Nucleoprotein and Phosphoprotein: From Predictions to Experimental Assessment. (2010)

Habchi J, Mamelli L, Darbon H, Longhi S.

PLoS One 5 e11684 PMID:20657787
Mammalian G protein-coupled receptor expression in Escherichia coli: II. Refolding and biophysical characterization of mouse cannabinoid receptor 1 and human parathyroid hormone receptor 1. (2010)

Michalke K, Huyghe C, Lichiere J, Graviere ME, Siponen M, Sciara G, Lepaul I, Wagner R, Magg C, Rudolph R, Cambillau C, Desmyter A.

Anal Biochem 401 74-80 PMID:20175983
Crystal structure of Bacillus subtilis SPP1 phage gp22 shares fold similarity with a domain of lactococcal phage p2 RBP. (2010)

Veesler D, Blangy S, Spinelli S, Tavares P, Campanacci V, Cambillau C.

Protein Sci 19 1439-1443 PMID:20506290
Structure of lactococcal phage p2 baseplate and its mechanism of activation. (2010)

Sciara G, Bebeacua C, Bron P, Tremblay D, Ortiz-Lombardia M, Lichiere J, van Heel M, Campanacci V, Moineau S, Cambillau C.

Proc Natl Acad Sci U S A 107 6852-7 PMID:20351260
Structure of the Pseudomonas aeruginosa XcpT pseudopilin, a major component of the Type II Secretion System. (2010)

Alphonse S, Durand E, Douzi B, Waegele B, Darbon H, Filloux A, Voulhoux R, Bernard C.

J Struct Biol 169 75-80 PMID:19747550
ORF 157 from the Archaeal Virus AFV1 Defines a New Class of Nuclease. (2010)

Goulet A, Redder P, Pina M, Prangishvili D, Vera L, Lichiere J, Leulliot N, van Tilbeurgh H, Ortiz-Lombardia M, Campanacci V, Cambillau C.

J Virol 84 5025-31 PMID:20200253
Deciphering the function of lactococcal phage ul36 Sak domains. (2010)

Scaltriti E, Moineau S, Launay H, Masson JY, Rivetti C, Ramoni R, Campanacci V, Tegoni M, Cambillau C.

J Struct Biol 170 462-9 PMID:20036743
Getting the best out of long-wavelength X-rays: de novo chlorine/sulfur SAD phasing of a structural protein from ATV. (2010)

Goulet A, Vestergaard G, Felisberto-Rodrigues C, Campanacci V, Garrett RA, Cambillau C, Ortiz-Lombardia M.

Acta Crystallogr D Biol Crystallogr 66 304-8 PMID:20179342

2009

A protein encoded by a new family of mobile elements from Euryarchaea exhibits three domains with novel folds. (2009)

Keller J, Leulliot N, Soler N, Collinet B, Vincentelli R, Forterre P, van Tilbeurgh H.

Protein Sci 18 850-5 PMID:19319959
Crystal structure of AFV1-102, a protein from the acidianus filamentous virus 1. (2009)

Keller J, Leulliot N, Collinet B, Campanacci V, Cambillau C, Pranghisvilli D, van Tilbeurgh H.

Protein Sci 18 845-849 PMID:19319936
Crystal structure of a chimeric receptor binding protein constructed from two lactococcal phages. (2009)

Siponen M, Spinelli S, Blangy S, Moineau S, Cambillau C, Campanacci V.

J Bacteriol 191 3220-5 PMID:19286807
Determination with maldi tof/tof of the extensive disulfide bonding in tarantula venom peptide PcFK1 (2009)

Combes G, Bernard C, Choi SJ, Pimentel C, Darbon H, Waidelich D, Mestivier D, Camadro JM.

Eur J Mass Spectrom 15 517-529 PMID:0
Acidianus filamentous virus 1 coat proteins display a helical fold spanning the filamentous archaeal viruses lineage. (2009)

Goulet A, Blangy S, Redder P, Prangishvili D, Felisberto-Rodrigues C, Forterre P, Campanacci V, Cambillau C.

Proc Natl Acad Sci U S A 106 21155-60 PMID:19934032
The crystal structure of ORF14 from Sulfolobus islandicus filamentous virus. (2009)

Goulet A, Spinelli S, Blangy S, van Tilbeurgh H, Leulliot N, Basta T, Prangishvili D, Cambillau C, Campanacci V.

Proteins 76 1020-2 PMID:19452552
The thermo- and acido-stable ORF-99 from the archaeal virus AFV1. (2009)

Goulet A, Spinelli S, Blangy S, van Tilbeurgh H, Leulliot N, Basta T, Prangishvili D, Cambillau C, Campanacci V.

Protein Sci 18 1316-20 PMID:19472363
Surfactant poloxamer 188 as a new crystallizing agent for urate oxydase (2009)

Giffard M, Delfosse V, Sciara G, Mayer C, Cambillau C, El Hajji M, Castro B, Bonnete F.

Crystal growth and design 9 4199-4206 PMID:0
Crystal structure and function of a DARPin neutralizing inhibitor of lactococcal phage TP901-1: Comparison of DARPin and camelid VHH binding mode. (2009)

Veesler D, Dreier B, Blangy S, Lichiere J, Tremblay D, Moineau S, Spinelli S, Tegoni M, Pluckthun A, Campanacci V, Cambillau C.

J Biol Chem 284 30718-30726 PMID:19740746
The XcpV/GspI pseudopilin has a central role in the assembly of a quaternary complex within the T2SS pseudopilus. (2009)

Douzi B, Durand E, Bernard C, Alphonse S, Cambillau C, Filloux A, Tegoni M, Voulhoux R.

J Biol Chem 284 34580-34589 PMID:19828448
Structure and function of phage p2 ORF34(p2), a new type of single-stranded DNA binding protein. (2009)

Scaltriti E, Tegoni M, Rivetti C, Launay H, Masson JY, Magadan AH, Tremblay D, Moineau S, Ramoni R, Lichiere J, Campanacci V, Cambillau C, Ortiz-Lombardia M.

Mol Microbiol 73(6) 1156-70 PMID:19719513
Insecticidal peptides from the theraposid spider Brachypelma albiceps: An NMR-based model of Ba2. (2009)

Corzo G, Bernard C, Clement H, Villegas E, Bosmans F, Tytgat J, Possani LD, Darbon H, Alagon A.

Biochim Biophys Acta 1794(8) 1190-6 PMID:19374957
Queen bee pheromone binding protein ph induced domain-swapping favors pheromone release. (2009)

Pesenti ME, Spinelli S, Bezirard V, Briand L, Pernollet JC, Campanacci V, Tegoni M, Cambillau C.

J Mol Biol 390(5) 981-90 PMID:19481550
The interaction between the measles virus nucleoprotein and the Interferon Regulator Factor 3 relies on a specific cellular environment. (2009)

Colombo M, Bourhis JM, Chamontin C, Soriano C, Villet S, Costanzo S, Couturier M, Belle V, Fournel A, Darbon H, Gerlier D, Longhi S.

Virol J 6 59 PMID:19445677
Interaction between the C-terminal domains of N and P proteins of measles virus investigated by NMR. (2009)

Bernard C, Gely S, Bourhis JM, Morelli X, Longhi S, Darbon H.

FEBS Lett 583 (7) 1084-9 PMID:19275899
Revised Mimivirus major capsid protein sequence reveals intron-containing gene structure and extra domain. (2009)

Azza S, Cambillau C, Raoult D, Suzan-Monti M.

BMC Mol Biol 10 39 PMID:19432951
Mammalian G-protein-coupled receptor expression in Escherichia coli: I. High-throughput large-scale production as inclusion bodies. (2009)

Michalke K, Graviere ME, Huyghe C, Vincentelli R, Wagner R, Pattus F, Schroeder K, Oschmann J, Rudolph R, Cambillau C, Desmyter A.

Anal Biochem 386 147-155 PMID:19150325
Production and biophysical characterization of the CorA transporter from Methanosarcina mazei. (2009)

Veesler D, Blangy S, Siponen M, Vincentelli R, Cambillau C, Sciara G.

Anal Biochem 388 115-121 PMID:19233118
Camelid nanobodies raised against an integral membrane enzyme, nitric oxide reductase. (2009)

Conrath K, Pereira AS, Martins CE, Timoteo CG, Tavares P, Spinelli S, Kinne J, Flaudrops C, Cambillau C, Muyldermans S, Moura I, Moura JJ, Tegoni M, Desmyter A.

Protein Sci 18 619-28 PMID:19241371
Crystal Structure of ORF12 from Lactococcus lactis phage p2 Identifies a Tape Measure Protein Chaperone. (2009)

Siponen M, Sciara G, Villion M, Spinelli S, Lichiere J, Cambillau C, Moineau S, Campanacci V.

J Bacteriol 191 728-734 PMID:19047351

2008

Chemical Synthesis and Characterization of J46 Peptide, an Atypical Class IIa Bacteriocin from Lactococcus lactis subsp. cremoris J46 Strain. (2008)

Lasta S, Fajloun Z, Darbon H, Mansuelle P, Andreotti N, Sabatier JM, Boudabous A, Sampieri F.

J Antibiot 61 89-93 PMID:18408329
Protein production and purification. (2008)

Graslund S, Nordlund P, Weigelt J, Hallberg BM, Bray J, Gileadi O, Knapp S, Oppermann U, Arrowsmith C, Hui R, Ming J, dhe-Paganon S, Park HW, Savchenko A, Yee A, Edwards A, Vincentelli R, Cambillau C, Kim R, Kim SH, Rao Z, Shi Y, Terwilliger TC, Kim CY, Hung LW, Waldo GS, Peleg Y, Albeck S, Unger T, Dym O, Prilusky J, Sussman JL, Stevens RC, Lesley SA, Wilson IA, Joachimiak A, Collart F, Dementieva I, Donnelly MI, Eschenfeldt WH, Kim Y, Stols L, Wu R, Zhou M, Burley SK, Emtage JS, Sauder JM, Thompson D, Bain K, Luz J, Gheyi T, Zhang F, Atwell S, Almo SC, Bonanno JB, Fiser A, Swaminathan S, Studier FW, Chance MR, Sali A, Acton TB, Xiao R, Zhao L, Ma LC, Hunt JF, Tong L, Cunningham K, Inouye M, Anderson S, Janjua H, Shastry R, Ho CK, Wang D, Wang H, Jiang M, Montelione GT, Stuart DI, Owens RJ, Daenke S, Schutz A, Heinemann U, Yokoyama S, Bussow K, Gunsalus KC.

Nat Methods 5 135-46 PMID:18235434
Structure of Locusta migratoria protease inhibitor 3 (LMPI-3) in complex with Fusarium oxysporum trypsin. (2008)

Leone P, Roussel A, Kellenberger C.

Acta Crystallogr D Biol Crystallogr 64 1165-1171 PMID:19020355
Epileptic and developmental disorders of the speech cortex: ligand/receptor interaction of wild-type and mutant SRPX2 with the plasminogen activator receptor uPAR. (2008)

Royer-Zemmour B, Ponsole-Lenfant M, Gara H, Roll P, Leveque C, Massacrier A, Ferracci G, Cillario J, Robaglia-Schlupp A, Vincentelli R, Cau P, Szepetowski P.

Hum Mol Genet 17 3617-30 PMID:18718938
There is a baby in the bath water: AcrB contamination is a major problem in membrane-protein crystallization. (2008)

Veesler D, Blangy S, Cambillau C, Sciara G.

Acta Crystallogr Sect F Struct Biol Cryst Commun 64 880-5 PMID:18931428
Structure of Human Pancreatic Lipase-Related Protein 2 with the Lid in an Open Conformation. (2008)

Eydoux C, Spinelli S, Davis TL, Walker JR, Seitova A, Dhe-Paganon S, De Caro A, Cambillau C, Carriere F.

Biochemistry 47(36) 9553-64 PMID:18702514
Structural Basis of the Honey Bee PBP Pheromone and pH-induced Conformational Change. (2008)

Pesenti ME, Spinelli S, Bezirard V, Briand L, Pernollet JC, Tegoni M, Cambillau C.

J Mol Biol 380 158-169 PMID:18508083
The VIZIER project: Preparedness against pathogenic RNA viruses. (2008)

Coutard B, Gorbalenya AE, Snijder EJ, Leontovich AM, Poupon A, De Lamballerie X, Charrel R, Gould EA, Gunther S, Norder H, Klempa B, Bourhy H, Rohayem J, L'hermite E, Nordlund P, Stuart DI, Owens RJ, Grimes JM, Tucker PA, Bolognesi M, Mattevi A, Coll M, Jones TA, Aqvist J, Unge T, Hilgenfeld R, Bricogne G, Neyts J, La Colla P, Puerstinger G, Gonzalez JP, Leroy E, Cambillau C, Romette JL, Canard B.

Antiviral Res 78 37-46 PMID:18083241
Differential Substrate Specificity and Kinetic Behavior in Escherichia coli YfdW and Oxalobacter formigenes Formyl-CoA Transferase. (2008)

Toyota CG, Berthold CL, Gruez A, Jonsson S, Lindqvist Y, Cambillau C, Richards NG..

J Bacteriol 190 2556-64 PMID:18245280
Deswapping bovine odorant binding protein. (2008)

Ramoni R, Spinelli S, Grolli S, Conti V, Merli E, Cambillau C, Tegoni M.

Biochim Biophys Acta 1784 651-7 PMID:18269920
A topological model of the baseplate of lactococcal phage tuc2009. (2008)

Sciara G, Blangy S, Siponen M, Mc Grath S, van Sinderen D, Tegoni M, Cambillau C, Campanacci V.

J Biol Chem 283 2716-23 PMID:18045876
Chemical synthesis and 1H-NMR 3D structure determination of AgTx2-MTX chimera, a new potential blocker for Kv1.2 channel, derived from MTX and AgTx2 scorpion toxins. (2008)

Pimentel C, M'barek S, Visan V, Grissmer S, Sampieri F, Sabatier JM, Darbon H, Fajloun Z.

Protein Sci 17 107-18 PMID:18042681

2007

ProteomeBinders: planning a European resource of affinity reagents for analysis of the human proteome. (2007)

Taussig MJ, Stoevesandt O, Borrebaeck CA, Bradbury AR, Cahill D, Cambillau C, de Daruvar A, Dubel S, Eichler J, Frank R, Gibson TJ, Gloriam D, Gold L, Herberg FW, Hermjakob H, Hoheisel JD, Joos TO, Kallioniemi O, Koegll M, Konthur Z, Korn B, Kremmer E, Krobitsch S, Landegren U, van der Maarel S, McCafferty J, Muyldermans S, Nygren PA, Palcy S, Pluckthun A, Polic B, Przybylski M, Saviranta P, Sawyer A, Sherman DJ, Skerra A, Templin M, Ueffing M, Uhlen M.

Nat Methods 4 13-7 PMID:17195019
Critical amino acid residues of maurocalcine involved in pharmacology, lipid interaction and cell penetration. (2007)

Mabrouk K, Ram N, Boisseau S, Strappazzon F, Rehaim A, Sadoul R, Darbon H, Ronjat M, De Waard M.

Biochim Biophys Acta 1768 2528-40 PMID:17888395
Improved crystallization of the coxsackievirus B3 RNA-dependent RNA polymerase. (2007)

Jabafi I, Selisko B, Coutard B, De Palma AM, Neyts J, Egloff MP, Grisel S, Dalle K, Campanacci V, Spinelli S, Cambillau C, Canard B, Gruez A.

Acta Crystallogr Sect F Struct Biol Cryst Commun 63 495-8 PMID:17554171
How much can a T-cell antigen receptor adapt to structurally distinct antigenic peptides? (2007)

Mazza C, Auphan-Anezin N, Gregoire C, Guimezanes A, Kellenberger C, Roussel A, Kearney A, van der Merwe PA, Schmitt-Verhulst AM, Malissen B.

EMBO J 26 1972-83 PMID:17363906
Crystal structure of AFV3-109, a highly conserved protein from crenarchaeal viruses. (2007)

Keller J, Leulliot N, Cambillau C, Campanacci V, Porciero S, Prangishvilli D, Forterre P, Cortez D, Quevillon-Cheruel S, van Tilbeurgh H.

Virol J 4 12 PMID:17241456

2006

Recombinant protein expression and solubility screening in Escherichia coli: a comparative study. (2006)

Berrow NS, Bussow K, Coutard B, Diprose J, Ekberg M, Folkers GE, Levy N, Lieu V, Owens RJ, Peleg Y, Pinaglia C, Quevillon-Cheruel S, Salim L, Scheich C, Vincentelli R, Busso D.

Acta Crystallogr D Biol Crystallogr 62 1218-26 PMID:17001098
Combining site-specific mutagenesis and seeding as a strategy to crystallize 'difficult' proteins: the case of Staphylococcus aureus thioredoxin. (2006)

Roos G, Brosens E, Wahni K, Desmyter A, Spinelli S, Wyns L, Messens J, Loris R.

Acta Crystallogr Sect F Struct Biol Cryst Commun 62 1255-8 PMID:17142910
Crystal structure of the temperature-sensitive and allosteric-defective chaperonin GroELE461K. (2006)

Cabo-Bilbao A, Spinelli S, Sot B, Agirre J, Mechaly AE, Muga A, Guerin DM.

J Struct Biol 155 482-92 PMID:16904907
Crystal structure of LppX, a lipoprotein required for the translocation of phthiocerol dimycocerosates to the surface of Mycobacterium tuberculosis (2006)

Sulzenbacher G, Canaan S, Bordat Y, Neyrolles O, Stadthagen G, Roig-Zamboni V, Rauzier J, Maurin D, Laval F, Daffe M, Cambillau C, Gicquel B, Bourne Y, Jackson M.

Colloque de l�Association Fran�aise de Cristallographie Toulouse, Juillet 2006 PMID:0
Distinct orientation of the alloreactive monoclonal CD8 T cell activation program by three different peptide/MHC complexes. (2006)

Auphan-Anezin N, Mazza C, Guimezanes A, Barrett-Wilt GA, Montero-Julian F, Roussel A, Hunt DF, Malissen B, Schmitt-Verhulst AM.

Eur J Immunol 36 1856-66 PMID:16761314
Discovery of an RNA virus 3' > 5' exoribonuclease that is critically involved in coronavirus RNA synthesis. (2006)

Minskaia E, Hertzig T, Gorbalenya AE, Campanacci V, Cambillau C, Canard B, Ziebuhr J.

Proc Natl Acad Sci U S A 103 5108-13 PMID:16549795
Crystal Structure and Mechanistic Determinants of SARS Coronavirus Nonstructural Protein 15 Define a Novel Endoribonuclease Family (2006)

Ricagno S, Egloff MP, Ulferts R, Coutard B, Nurizzo D, Campanacci V, Cambillau C, Ziebuhr J, Canard B.

Proc Natl Acad Sci U S A 103 11892-7 PMID:16882730
Structural and Functional Basis for ADP-ribose and Poly(ADP-Ribose) binding by Viral Macro Domains (2006)

Egloff MP, Malet H, Putics A, Heinonen M, Dutartre H, Frangeul A, Gruez A, Campanacci V, Cambillau C, Zieebuhr J, Ahola T, Canard B.

J Virol 80 8493-502 PMID:16912299
Structural genomics on membrane proteins: comparison of more than 100 GPCRs in 3 expression systems. (2006)

Lundstrom K, Wagner R, Reinhart C, Desmyter A, Cherouati N, Magnin T, Zeder-Lutz G, Courtot M, Prual C, Andre N, Hassaine G, Michel H, Cambillau C, Pattus F.

J Struct Funct Genomics 7 77-91 PMID:17120110
An archaeal peptidase assembles into two different quaternary structures: A tetrahedron and a giant octahedron. (2006)

Schoehn G, Vellieux FM, Dura MA, Receveur-Brechot V, Fabry CM, Ruigrok RW, Ebel C, Roussel A, Franzetti B.

J Biol Chem 281 36327-36337 PMID:16973604
Implementation of semi-automated cloning and prokaryotic expression screening: the impact of SPINE. (2006)

Alzari PM, Berglund H, Berrow NS, Blagova E, Busso D, Cambillau C, Campanacci V, Christodoulou E, Eiler S, Fogg MJ, Folkers G, Geerlof A, Hart D, Haouz A, Herman MD, Macieira S, Nordlund P, Perrakis A, Quevillon-Cheruel S, Tarandeau F, van Tilbeurgh H, Unger T, Luna-Vargas MP, Velarde M, Willmanns M, Owens RJ.

Acta Crystallogr D Biol Crystallogr 62 1103-13 PMID:17001088
Application of the use of high-throughput technologies to the determination of protein structures of bacterial and viral pathogens. (2006)

Fogg MJ, Alzari P, Bahar M, Bertini I, Betton JM, Burmeister WP, Cambillau C, Canard B, Carrondo M, Coll M, Daenke S, Dym O, Egloff MP, Enguita FJ, Geerlof A, Haouz A, Jones TA, Ma Q, Manicka SN, Migliardi M, Nordlund P, Owens RJ, Peleg Y, Schneider G, Schnell R, Stuart DI, Tarbouriech N, Unge T, Wilkinson AJ, Wilmanns M, Wilson KS, Zimhony O, Grimes JM.

Acta Crystallogr D Biol Crystallogr 62 1196-207 PMID:17001096
SPINE bioinformatics and data-management aspects of high-throughput structural biology. (2006)

Albeck S, Alzari P, Andreini C, Banci L, Berry IM, Bertini I, Cambillau C, Canard B, Carter L, Cohen SX, Diprose JM, Dym O, Esnouf RM, Felder C, Ferron F, Guillemot F, Hamer R, Ben Jelloul M, Laskowski RA, Laurent T, Longhi S, Lopez R, Luchinat C, Malet H, Mochel T, Morris RJ, Moulinier L, Oinn T, Pajon A, Peleg Y, Perrakis A, Poch O, Prilusky J, Rachedi A, Ripp R, Rosato A, Silman I, Stuart DI, Sussman JL, Thierry JC, Thompson JD, Thornton JM, Unger T, Vaughan B, Vranken W, Watson JD, Whamond G, Henrick K.

Acta Crystallogr D Biol Crystallogr 62 1184-95 PMID:17001095
Crystallization and preliminary X-ray diffraction analysis of protein 14 from Sulfolobus islandicus filamentous virus (SIFV). (2006)

Goulet A, Spinelli S, Campanacci V, Porciero S, Blangy S, Garrett RA, van Tilbeurgh H, Leulliot N, Basta T, Prangishvili D, Cambillau C.

Acta Crystallogr Sect F Struct Biol Cryst Commun 62 884-6 PMID:16946470
Crystal Structure of the Receptor-Binding Protein Head Domain from Lactococcus lactis Phage bIL170. (2006)

Ricagno S, Campanacci V, Blangy S, Spinelli S, Tremblay D, Moineau S, Tegoni M, Cambillau C.

J Virol 80 9331-5 PMID:16940545
The membrane bound bacterial lipocalin Blc is a functional dimer with binding preference for lysophospholipids. (2006)

Campanacci V, Bishop RE, Blangy S, Tegoni M, Cambillau C.

FEBS Lett 580 4877-83 PMID:16920109
Modular structure of the receptor binding proteins of lactococcus lactis phages: The RBP structure of the temperate phage TP901-1. (2006)

Spinelli S, Campanacci V, Blangy S, Moineau S, Tegoni M, Cambillau C.

J Biol Chem 281 14256-62 PMID:16549427
LppX is a lipoprotein required for the translocation of phthiocerol dimycocerosates to the surface of Mycobacterium tuberculosis (2006)

Sulzenbacher G, Canaan S, Bordat Y, Neyrolles O, Stadthagen G, Roig-Zamboni V, Rauzier J, Maurin D, Laval F, Daffe M, Cambillau C, Gicquel B, Bourne Y, Jackson M.

EMBO J 25 1436-1444 PMID:16541102
Solution structure of PcFK1, a spider peptide active against Plasmodium falciparum. (2006)

Pimentel C, Choi SJ, Chagot B, Guette C, Camadro JM, Darbon H.

Protein Sci 15 628-634 PMID:16452619
Crystallization and preliminary X-ray diffraction analysis of Nsp15 from SARS coronavirus. (2006)

Ricagno S, Coutard B, Grisel S, Bremond N, Dalle K, Tocque F, Campanacci V, Lichiere J, Lantez V, Debarnot C, Cambillau C, Canard B, Egloff MP.

Acta Crystallogr Sect F Struct Biol Cryst Commun 62 409-411 PMID:16582498
Expression, purification and crystallization of the SARS-CoV macro domain. (2006)

Malet H, Dalle K, Bremond N, Tocque F, Blangy S, Campanacci V, Coutard B, Grisel S, Lichiere J, Lantez V, Cambillau C, Canard B, Egloff MP.

Acta Crystallogr Sect F Struct Biol Cryst Commun 62 405-8 PMID:16582497
Receptor-Binding Protein of Lactococcus lactis Phages: Identification and Characterization of the Saccharide Receptor-Binding Site. (2006)

Tremblay DM, Tegoni M, Spinelli S, Campanacci V, Blangy S, Huyghe C, Desmyter A, Labrie S, Moineau S, Cambillau C.

J Bacteriol 188 2400-10 PMID:16547026
Crystal structure at 1.45-A resolution of the major allergen endo-beta-1,3-glucanase of banana as a molecular basis for the latex-fruit syndrome. (2006)

Receveur-Brechot V, Czjzek M, Barre A, Roussel A, Peumans WJ, Van Damme EJ, Rouge P.

Proteins 63 235-42 PMID:16421930
Lactococcal bacteriophage p2 receptor-binding protein structure suggests a common ancestor gene with bacterial and mammalian viruses. (2006)

Spinelli S, Desmyter A, Verrips CT, de Haard HJ, Moineau S, Cambillau C.

Nat Struct Mol Biol 13 85-9 PMID:16327804
Pharmacological profiling of Orthochirus scrobiculosus toxin 1 analogues with a trimmed N-terminal domain. (2006)

Mouhat S, Teodorescu G, Homerick D, Visan V, Wulff H, Wu Y, Grissmer S, Darbon H, De Waard M, Sabatier JM.

Mol Pharmacol 69 354-62 PMID:16234482
Resolution of the structure of the allergenic and antifungal banana fruit thaumatin-like protein at 1.7-A. (2006)

Leone P, Menu-Bouaouiche L, Peumans WJ, Payan F, Barre A, Roussel A, Van Damme EJ, Rouge P.

Biochimie 88 45-52 PMID:16085352

2005

Expression, purification, crystallization and preliminary crystallographic analysis of a deblocking amino peptidase from Pyrococcus horikoshii (2005)

Porciero S, Receveur-Brechot V, Mori K, Franzetti B, Roussel A.

Acta Crystallogr Sect F Struct Biol Cryst Commun F61 239-242 PMID:16511005
Increasing the molecular contacts between maurotoxin and Kv1.2 channel augments ligand affinity. (2005)

M Barek S, Chagot B, Andreotti N, Visan V, Mansuelle P, Grissmer S, Marrakchi M, El Ayeb M, Sampieri F, Darbon H, Fajloun Z, De Waard M, Sabatier JM.

Proteins 60 401-11 PMID:15971207
Induction of morphological changes in model lipid membranes and the mechanism of membrane disruption by a large scorpion-derived pore-forming peptide. (2005)

Nomura K, Ferrat G, Nakajima T, Darbon H, Iwashita T, Corzo G.

Biophys J 89 4067-4080 PMID:16199510
The impact of the fourth disulfide bridge in scorpion toxins of the alpha-KTx6 subfamily. (2005)

Carrega L, Mosbah A, Ferrat G, Beeton C, Andreotti N, Mansuelle P, Darbon H, De Waard M, Sabatier JM.

Proteins 61 1010-1023 PMID:16247791
Automated expression and solubility screening of His-tagged proteins in 96-well format. (2005)

Vincentelli R, Canaan S, Offant J, Cambillau C, Bignon C.

Anal Biochem 346 77-84 PMID:16168382
A mutation designed to alter crystal packing permits structural analysis of a tight-binding fluorescein-scFv complex. (2005)

Honegger A, Spinelli S, Cambillau C, Pluckthun A.

Protein Sci 14 2537-49 PMID:16195545
Glu-Q-tRNA(Asp) synthetase coded by the yadB gene, a new paralog of aminoacyl-tRNA synthetase that glutamylates tRNA(Asp) anticodon. (2005)

Blaise M, Becker HD, Lapointe J, Cambillau C, Giege R, Kern D.

Biochimie 87 847-61 PMID:16164993
The H-2Kk MHC Peptide-Binding Groove Anchors the Backbone of an Octameric Antigenic Peptide in an Unprecedented Mode. (2005)

Kellenberger C, Roussel A, Malissen B.

J Immunol 175 3819-3825 PMID:16148128
Solution structure of APETx2, a specific peptide inhibitor of ASIC3 proton-gated channels. (2005)

Chagot B, Escoubas P, Diochot S, Bernard C, Lazdunski M, Darbon H.

Protein Sci 14 2003-2010 PMID:15987885
The intrinsically disordered C-terminal domain of the measles virus nucleoprotein interacts with the C-terminal domain of the phosphoprotein via two distinct sites and remains predominantly unfolded. (2005)

Bourhis JM, Receveur-Brechot V, Oglesbee M, Zhang X, Buccellato M, Darbon H, Canard B, Finet S, Longhi S.

Protein Sci 14 1975-92 PMID:16046624
Structure-activity relationship within the serine protease inhibitors of the pacifastin family. (2005)

Kellenberger C, Roussel A.

Protein Pept Lett 12 409-14 PMID:16029152
Emergence of a subfamily of xylanase inhibitors within glycoside hydrolase family 18 (2005)

Durand A, Hughes R, Roussel A, Flatman R, Henrissat B, Juge N.

FEBS J 272 1745-1755 PMID:15794761
Induced refolding of a temperature denatured llama heavy-chain antibody fragment by its antigen. (2005)

Dolk E, van Vliet C, Perez JM, Vriend G, Darbon H, Ferrat G, Cambillau C, Frenken LG, Verrips T.

Proteins 59 555-564 PMID:15778955
An unusual fold for potassium channel blockers: NMR structure of three toxins from the scorpion Opisthacanthus madagascariensis. (2005)

Chagot B, Pimentel C, Dai L, Pil J, Tytgat J, Nakajima T, Corzo G, Darbon H, Ferrat G.

Biochem J 388 263-71 PMID:15631621
Solution structure of two insect-specific spider toxins and their pharmacological interaction with the insect voltage-gated Na(+) channel. (2005)

Ferrat G, Bosmans F, Tytgat J, Pimentel C, Chagot B, Gilles N, Nakajima T, Darbon H, Corzo G.

Proteins 59 368-79 PMID:15726637
Solution structure of APETx1 from the sea anemone Anthopleura elegantissima: A new fold for an HERG toxin. (2005)

Chagot B, Diochot S, Pimentel C, Lazdunski M, Darbon H.

Proteins 59 380-6 PMID:15726634
VaZyMolO: a tool to define and classify modularity in viral proteins. (2005)

Ferron F, Rancurel C, Longhi S, Cambillau C, Henrissat B, Canard B.

J Gen Virol 86 743-749 PMID:15722535
Characterization of a TET-like Aminopeptidase Complex from the Hyperthermophilic Archaeon Pyrococcus horikoshii. (2005)

Dura MA, Receveur-Brechot V, Andrieu JP, Ebel C, Schoehn G, Roussel A, Franzetti B.

Biochemistry 44 3477-86 PMID:15736957
Isolation of llama antibody fragments for prevention of dandruff by phage display in shampoo. (2005)

Dolk E, van der Vaart M, Lutje Hulsik D, Vriend G, de Haard H, Spinelli S, Cambillau C, Frenken L, Verrips T.

Appl Environ Microbiol 71 442-50 PMID:15640220
Crystal structure of the conserved hypothetical protein Rv1155 from Mycobacterium tuberculosis. (2005)

Canaan S, Sulzenbacher G, Roig-Zamboni V, Scappuccini-Calvo L, Frassinetti F, Maurin D, Cambillau C, Bourne Y.

FEBS Lett 579 215-21 PMID:15620716
K(+) channel types targeted by synthetic OSK1, a toxin from Orthochirus scrobiculosus scorpion venom. (2005)

Mouhat S, Visan V, Ananthakrishnan S, Wulff H, Andreotti N, Grissmer S, Darbon H, De Waard M, Sabatier JM.

Biochem J 385 95-104 PMID:15588251

2004

The severe acute respiratory syndrome-coronavirus replicative protein nsp9 is a single-stranded RNA-binding subunit unique in the RNA virus world (2004)

Egloff MP, Ferron F, Campanacci V, Longhi S, Rancurel C, Dutartre H,Snijder EJ, Gorbalenya AE, Cambillau C, Canard B.

Proc Natl Acad Sci U S A 101 3792-2796 PMID:15007178
Solution structure of Phrixotoxin 1, a specific peptide inhibitor of Kv4 potassium channels from the venom of the theraphosid spider Phrixotrichus auratus (2004)

Chagot B, Escoubas P, Villegas E, Bernard C, Ferrat G, Corzo G, Lazdunski G, Darbon H.

Protein Sci 13 1197-1208 PMID:15096626
Evidence for domain-specific recognition of SK and Kv channels by MTX and HsTx1 scorpion toxins. (2004)

Regaya I, Beeton C, Ferrat G, Andreotti N, Darbon H, De Waard M, Sabatier JM.

J Biol Chem 279 55690-55696 PMID:15498765
Plant stress proteins of the thaumatin-like family discovered in animals (2004)

Brandazza A, Angeli S, Tegoni M, Cambillau C, Pelosi P.

FEBS Lett 572 3-7 PMID:15304314
High-throughput automated refolding screening of inclusion bodies (2004)

Vincentelli R, Canaan S, Campanacci V, Valencia C, Maurin D, Frassinetti F, Scappucini-Calvo L, Cambillau C, Bignon C.

Protein Sci 13 2782-2792 PMID:15388864
Crystal Structure and Kinetics Identify Escherichia coli YdcW Gene Product as a Medium-chain Aldehyde Dehydrogenase (2004)

Gruez A, Roig-Zamboni V, Grisel S, Salomoni A, Valencia C, Campanacci V, Tegoni M, Cambillau C.

J Mol Biol 343 29-41 PMID:15381418
Structure of Escherichia coli YhdH, a putative quinone oxidoreductase. (2004)

Sulzenbacher G, Roig-Zamboni V, Pagot F, Grisel S, Salomoni A, Valencia C, Campanacci V, Vincentelli R, Tegoni M, Eklund H, Cambillau C.

Acta Crystallogr D Biol Crystallogr 60 1855-62 PMID:15388933
Functional importance of Asp37 from a family 11 xylanase in the binding to two proteinaceous xylanase inhibitors from wheat. (2004)

Tahir TA, Durand A, Gebruers K, Roussel A, Williamson G, Juge N.

FEMS Microbiol Lett 239 9-15 PMID:15451095
Crystal structures of bovine odorant-binding protein in complex with odorant molecules. (2004)

Vincent F, Ramoni R, Spinelli S, Grolli S, Tegoni M, Cambillau C.

Eur J Biochem 271 3832-3842 PMID:15373829
Expression and characterization of the protein Rv1399c from Mycobacterium tuberculosis: a novel carboxyl esterase structurally related to the HSL family (2004)

Canaan S, Maurin D, Chahinian H, Pouilly B, Durousseau C, Frassinetti F, Scappuccini-Calvo L, Cambillau C, Bourne Y.

Eur J Biochem 271 3953-3961 PMID:15373841
The dual nature of the wheat xylanase protein inhibitor XIP-I - structural basis for the inhibition of family 10 and family 11 xylanases (2004)

Payan F, Leone P, Porciero S, Furniss C,Tahir T, Williamson G, Durand A, Manzanares P, Gilbert H, Juge N, Roussel A.

J Biol Chem 279 36029-36037 PMID:15181003
Crystal structure and reactivity of YbdL from Escherichia coli identify a methionine aminotransferase function. (2004)

Dolzan M, Johansson K, Roig-Zamboni V, Campanacci V, Tegoni M, Schneider G, Cambillau C.

FEBS Lett 571 141-146 PMID:15280032
Crystal Structure of E.coli Alcohol Dehydrogenase YqhD: Evidence of a Covalently Modified NADP Coenzyme. (2004)

Sulzenbacher G, Alvarez K, Van Den Heuvel RH, Versluis C, Spinelli S, Campanacci V, Valencia C, Cambillau C, Eklund H, Tegoni M.

J Mol Biol 342 489-502 PMID:15327949
Expression, refolding, crystallization and preliminary crystallographic study of MHC H-2K(k) complexed with octapeptides and nonapeptides. (2004)

Kellenberger C, Porciero S, Roussel A.

Acta Crystallogr D Biol Crystallogr 60 1278-80 PMID:15213391
A minimalist glutamyl-tRNA synthetase dedicated to aminoacylation of the tRNAAsp QUC anticodon. (2004)

Blaise M, Becker HD, Keith G, Cambillau C, Lapointe J, Giege R, Kern D.

Nucleic Acids Res 32 2768-75 PMID:15150343
An aminoacyl-tRNA synthetase-like protein encoded by the Escherichia coli yadB gene glutamylates specifically tRNAAsp. (2004)

Dubois DY, Blaise M, Becker HD, Campanacci V, Keith G, Giege R, Cambillau C, Lapointe J, Kern D.

Proc Natl Acad Sci U S A 101 7530-7535 PMID:15096594
Structural aspects of sexual attraction and chemical communication in insects (2004)

Tegoni M, Campanacci V, Cambillau C.

Trends Biochem Sci 29 257-264 PMID:15130562
Crystal structure of E. coli YddE protein reveals a striking homolgy with diaminopimelate epimerase (2004)

Grassick A, Sulzenbacher G, Roig-Zamboni V, Campanacci V, Cambillau C, Bourne Y.

Proteins 55 764-767 PMID:15103639
Directed in vitro evolution and crystallographic analysis of a peptide binding scFv antibody with low picomolar affinity. (2004)

Zahnd C, Spinelli S, Luginbuhl B, Amstutz P, Cambillau C, Pluckthun A.

J Biol Chem 279 18870-18877 PMID:14754898
Domain swapping of a llama VHH domain builds a crystal-wide beta-sheet structure. (2004)

Spinelli S, Desmyter A, Frenken L, Verrips T, Tegoni M, Cambillau C.

FEBS Lett 564 35-40 PMID:15094039
The crystal structure of the Escherichia coli lipocalin Blc suggests a possible role in phospholipid binding. (2004)

Campanacci V, Nurizzo D, Spinelli S, Valencia C, Tegoni M, Cambillau C.

FEBS Lett 562 183-8 PMID:15044022
The Escherichia coli YadB Gene Product Reveals a Novel Aminoacyl-tRNA Synthetase Like Activity (2004)

Campanacci V, Dubois DY, Becker HD, Kern D, Spinelli S, Valencia C, Pagot F, Salomoni A, Brisel S, Vincentelli R, Bignon C, Lapointe J, Giege R, Cambillau C.

J Mol Biol 337 273-283 PMID:15003446
Sulfur-SAD crystal structure of a pheromone binding protein from the honeybee apis mellifera L. (2004)

Lartigue A, Gruez A, Briand L, Blon F, Bezirard V, Walsh M, Pernollet JC, Tegoni M, Cambillau C.

J Biol Chem 279 4459-4464 PMID:14594955
Solution structure of ADO1, a toxin extracted from the saliva of the assassin bug, Agriosphodrus dohrni. (2004)

Bernard C, Corzo G, Adachi-Akahane S, Foures G, Kanemaru K, Furukawa Y, Nakajima T, Darbon H.

Proteins 54 195-205 PMID:14696181
The "functional" dyad of scorpion toxin Pi1 is not per se a prerequisite for toxin binding to the voltage-gated Kv1.2 potassium channels. (2004)

Mouhat S, Mosbah A, Visan V, Wulff H, Delepierre M, Darbon H, Grissmer S, De Waard M, Sabatier JM.

Biochem J 377 25-36 PMID:12962541

2003

Inhibition of Dog and Human Gastric Lipases by Enantiomeric Phosphonate Inhibitors: A Structure-Activity Study. (2003)

Miled N, Roussel A, Bussetta C, Berti-Dupuis L, Riviere M, Buono G, Verger R, Cambillau C, Canaan S.

Biochemistry 42 11587-11593 PMID:14529268
The solution structure of a chemosensory protein (CSP) from the moth Mamestra brassicae. (2003)

Mosbah A, Campanacci V, Lartigue A, Tegoni M, Cambillau C, Darbon H.

Biochem J 369 39-44 PMID:12217077
Rat kidney acylase I: further characterisation and mutation studies on the involvement of Glu 147 in the catalytic process. (2003)

Durand A, Giardina T, Villard C, Roussel A, Puigserver A, Perrier J.

Biochimie 85 953-62 PMID:14644550
Proteins - reflecting the diversity of life. (2003)

Cambillau C.

Curr Opin Struct Biol 13 655-7 PMID:14675541
Structural analysis of xylanase inhibitor protein I (XIP-I), a proteinaceous xylanase inhibitor from wheat (Triticum aestivum, var. Soisson). (2003)

Payan F, Flatman R, Porciero S, Williamson G, Juge N, Roussel A.

Biochem J 372 399-405 PMID:12617724
The Crystal Structure of the Escherichia coli YfdW Gene Product Reveals a New Fold of Two Interlaced Rings Identifying a Wide Family of CoA Transferases. (2003)

Gruez A, Roig-Zamboni V, Valencia C, Campanacci V, Cambillau C.

J Biol Chem 278 34582-34586 PMID:12844490
Optimization of crystals from nanodrops: crystallization and preliminary crystallographic study of a pheromone-binding protein from the honeybee Apis mellifera L. (2003)

Lartigue A, Gruez A, Briand L, Pernollet JC, Spinelli S, Tegoni M, Cambillau C.

Acta Crystallogr D Biol Crystallogr 59 919-921 PMID:12777812
Crystallization and preliminary crystallographic study of a pheromone-binding protein from the cockroach Leucophaea maderae. (2003)

Lartigue A, Riviere S, Brossut R, Tegoni M, Cambillau C.

Acta Crystallogr D Biol Crystallogr 59 916-918 PMID:12777811
Selective Inhibition of Trypsins by Insect Peptides: Role of P6-P10 Loop. (2003)

Kellenberger C, Ferrat G, Leone P, Darbon H, Roussel A.

Biochemistry 42 13605-13612 PMID:14622007
Crystal structure of the measles virus phosphoprotein domain responsible for the induced folding of the C-terminal domain of the nucleoprotein. (2003)

Johansson K, Bourhis JM, Campanacci V, Cambillau C, Canard B, Longhi S.

J Biol Chem 278 44567-73 PMID:12944395
The crystal stucture of nitrous oxide reductase of Paracoccus denitrificans at 1.6 Å resolution (2003)

Haltia T, Brown K, Tegoni M, Cambillau C, Saraste M, Djinovic-Carugo K.

Biochem J 369 77-88 PMID:12356332
Structural genomics of the SARS coronavirus: cloning, expression, crystallization and preliminary crystallographic study of the Nsp9 protein. (2003)

Campanacci V, Egloff MP, Longhi S, Ferron F, Rancurel C, Salomoni A, Durousseau C, Tocque F, Bremond N, Dobbe JC, Snijder EJ, Canard B, Cambillau C.

Acta Crystallogr D Biol Crystallogr 59 1628-31 PMID:12925794
A pheromone binding protein from the cockroach Leucophaea maderae: Cloning, expression and pheromone binding. (2003)

Riviere S, Lartigue A, Quennedey B, Campanacci V, Farine JP, Tegoni M, Cambillau C, Brossut R.

Biochem J 371 573-579 PMID:12529170
Electrochemical study of the intermolecular electron transfer to Pseudomonas aeruginosa cytochrome cd1 nitrite reductase (2003)

Lojou E, Cutruzzola F, Tegoni M, Bianco P.

Electrochimica acta 48 1055-1064 PMID:0
Moth chemosensory protein exhibits drastic conformational changes and cooperativity on ligand binding. (2003)

Campanacci V, Lartigue A, Hallberg BM, Jones TA, Giudici-Orticoni MT, Tegoni M, Cambillau C.

Proc Natl Acad Sci U S A 100 5069-5074 PMID:12697900
Medium-scale structural genomics: strategies for protein expression and crystallization. (2003)

Vincentelli R, Bignon C, Gruez A, Canaan S, Sulzenbacher G, Tegoni M, Campanacci V, Cambillau C.

Acc Chem Res 36 165-172 PMID:12641473
Functional consequences of deleting the two C-terminal residues of the scorpion toxin BmTX3. (2003)

Vacher H, Romi-Lebrun R, Crest M, Masmejean F, Bougis PE, Darbon H, Martin-Eauclaire MF.

Biochim Biophys Acta 1646 152-156 PMID:12637022
Evolutionary origin of inhibitor cystine knot peptides. (2003)

Zhu S, Darbon H, Dyason K, Verdonck F, Tytgat J.

FASEB J 17 1765-1767 PMID:12958203
Recombinant production and solution structure of PcTx1, the specific peptide inhibitor of ASIC1a proton-gated cation channels. (2003)

Escoubas P, Bernard C, Lambeau G, Lazdunski M, Darbon H.

Protein Sci 12 1332-1343 PMID:12824480
A maurotoxin with constrained standard disulfide bridging: innovative strategy of chemical synthesis, pharmacology, and docking on K+ channels. (2003)

M'Barek S, Lopez-Gonzalez I, Andreotti N, di Luccio E, Visan V, Grissmer S, Judge S, El Ayeb M, Darbon H, Rochat H, Sampieri F, Beraud E, Fajloun Z, De Waard M, Sabatier JM.

J Biol Chem 278 31095-31104 PMID:12783861
Quaternary structure of alpha-crustacyanin from lobster as seen by small-angle X-ray scattering. (2003)

Dellisanti CD, Spinelli S, Cambillau C, Findlay JB, Zagalsky PF, Finet S, Receveur-Brechot V.

FEBS Lett 544 189-193 PMID:12782314
The crystal structure of a cockroach pheromone-binding protein suggests a new ligand binding and release mechanism. (2003)

Lartigue A, Gruez A, Spinelli S, Riviere S, Brossut R, Tegoni M, Cambillau C.

J Biol Chem 278 30213-30218 PMID:12766173
Comparative membrane interaction study of viscotoxins A3, A2 and B from mistletoe (Viscum album) and connections with their structures. (2003)

Coulon A, Mosbah A, Lopez A, Sautereau AM, Schaller G, Urech K, Rouge P, Darbon H.

Biochem J 374 71-78 PMID:12733989
The C-terminal domain of the measles virus nucleoprotein is intrinsically disordered and folds upon binding to the C-terminal moiety of the phosphoprotein. (2003)

Longhi S, Receveur-Brechot V, Karlin D, Johansson K, Darbon H, Bhella D, Yeo R, Finet S, Canard B.

J Biol Chem 278 18638-48 PMID:12621042

2002

Boar salivary lipocalin. Three-dimensional X-ray structure and androsterol/androstenone docking simulations. (2002)

Spinelli S, Vincent F, Pelosi P, Tegoni M, Cambillau C..

Eur J Biochem 269 2449-56 PMID:12027882
Crystal structure of the open form of dog gastric lipase in complex with a phosphonate (2002)

Roussel A, Miled N, Berti-Dupuis L, Riviere M, Spinelli S, Berna P, Gruber V, Verger R, Cambillau C.

J Biol Chem 277 2266-2274 PMID:11689574
Cyanide Binding to cd(1) Nitrite Reductase from Pseudomonas aeruginosa: Role of the Active-Site His369 in Ligand Stabilization. (2002)

Sun W, Arese M, Brunori M, Nurizzo D, Brown K, Cambillau C, Tegoni M, Cutruzzolà F..

Biochem Biophys Res Commun 291 1-7 PMID:11829453
Synthesis, 3-D Structure, and Pharmacology of a Reticulated Chimeric Peptide Derived from Maurotoxin and Tsk Scorpion Toxins (2002)

Fajloun Z, Ferrat G, Carlier E, M'Barek S, Regaya I, Fathallah M, Rochat H, Darbon H, de Waard M, Sabatier JM.

Biochem Biophys Res Commun 291 640-648 PMID:11855838
Solution structure and relaxation studies of an antigen-free Heavy Chain Variable Domain (VHH) from Llama (2002)

Renisio JG, Pérez J, Czisch M, Guenneugues M, Bornet O, Frenken L, Cambillau C, Darbon H. .

Proteins 47 546-555 PMID:12001233
Synthesis, characterization, and application of cy-dye- and alexa-dye-labeled hongotoxin(1) analogues. The first high affinity fluorescence probes for voltage-gated K+ channels. (2002)

Pragl B, Koschak A, Trieb M, Obermair G, Kaufmann WA, Gerster U, Blanc E, Hahn C, Prinz H, Schutz G, Darbon H, Gruber HJ, Knaus HG..

Bioconjug Chem 13 416-425 PMID:12009929
A Hyperthermostable D-Ribose-5-Phosphate Isomerase from Pyrococcus horikoshii. Characterization and Three-Dimensional Structure (2002)

Ishikawa K, Matsui I, Payan F, Cambillau C, Ishida H, Kawarabayasi Y, Kikuchi H,Roussel A.

Structure 10 877-886 PMID:12057201
A peptide mimic of an antigenic loop of alpha-human chorionic gonadotropin hormone: solution structure and interaction with a llama (2002)

Ferrat G, Renisio JG, Morelli X, Slootstra J, Meloen R, Cambillau C, Darbon H..

Biochem J 366 415-422 PMID:11996668
Control of Domain Swapping in Bovine Odorant Binding Protein. (2002)

Ramoni R, Vincent F, Ashcroft AE, Accornero P, Grolli S, Valencia C, Tegoni M, Cambillau C..

Biochem J 365 739-748 PMID:11931632
Biophysical properties of camelid V(HH) domains compared to those of human V(H)3 domains. (2002)

Ewert S, Cambillau C, Conrath K, Pluckthun A..

Biochemistry 41 3628-3366 PMID:11888279
X-Ray structure and ligand binding study of a moth chemosensory protein (2002)

Lartigue A, Campanacci V, Roussel A, Larsson AM, Jones TA,Tegoni M, Cambillau C .

J Biol Chem 277 32094-32098 PMID:12068017
Direct in vivo screening of intrabody libraries constructed on a highly stable single-chain framework. (2002)

Auf Der Maur A, Zahnd C, Fischer F, Spinelli S, Honegger A, Cambillau C, Escher D, Pluckthun A, Barberis A.

J Biol Chem 277 45075-45085 PMID:12215438
Specific characterization of substrate and inhibitor binding sites of a glycosyl hydrolase family 11 xylanase from Aspergillus niger. (2002)

Tahir TA, Berrin JG, Flatman R, Roussel A, Roepstorff P, Williamson G, Juge N.

J Biol Chem 277 44035-44043 PMID:12207016
A medium-throughput crystallization approach. (2002)

Sulzenbacher G, Gruez A, Roig-Zamboni V, Spinelli S, Valencia C, Pagot F, Vincentelli R, Bignon C, Salomoni A, Grisel S, Maurin D, Huyghe C, Johansson K, Grassick A, Roussel A, Bourne Y, Perrier S, Miallau L, Cantau P, Blanc E, Genevois M, Grossi A, Zenatti A, Campanacci V, Cambillau C.

Acta Crystallogr D Biol Crystallogr 58 2109-2115 PMID:12454472
Assignment of the 1H, 13C, and 15N resonances of the 22.5 kDa CBM28 module of the cellulase Cel5I of Clostridium cellulolyticum. (2002)

Mosbah A, Tardif C, Bornet O, Valette O, Henrissat B, Darbon H.

J Biomol NMR 23 157-158 PMID:12153043
Three camelid VHH domains in complex with porcine pancreatic a-amylase: Inhibition and versatility of binding topology. (2002)

Desmyter A, Spinelli S, Payan F, Lauwereys M, Wyns L, Muyldermans S, Cambillau C.

J Biol Chem 277 23645-23650 PMID:11960990

2001

The nitrite reductase from Pseudomonas aeruginosa : Essential role of two active-site histidines in the catalytic and structural properties (2001)

Cutruzzola F, Brown K, Wilson EK, Bellelli A, Arese M, Tegoni M, Cambillau C, Brunori M.

Proc Natl Acad Sci U S A 98 2232-2237 PMID:11226222
The insect attractant, 1-octen-3-ol is the natural ligand of bovine odorant binding protein (2001)

Ramoni R, Vincent F, Grolli S, Conti V, Malosse C, Boyer FD,Nagnan-Le Meillour P, Spinelli S, Cambillau C, Tegoni M.

J Biol Chem 276 7150-7155 PMID:11114310
Crystal structure of Aphrodisin, a Sex Pheromone from Female Hamster (2001)

Vincent F, Loebel D, Brown K, Spinelli S, Grote P, Breer H, Cambillau C and Tegoni M.

J Mol Biol 305 459-469 PMID:11152604
Recombinant chemosensory protein (CSP2) from the moth Mamestra brassicae: crystallization and preliminary crystallographic study. (2001)

Campanacci V, Spinelli S, Lartigue A, Lewandowski C, Brown K, Tegoni M, Cambillau C.

Acta Crystallogr D Biol Crystallogr 57 137-139 PMID:11134936
Disulfide bridge reorganization induced by proline mutations in maurotoxin (2001)

Carlier E, Fajloun Z, Mansuelle P, Fathallah M, Mosbah A, Oughideni R, Di Luccio E, Sandoz G, Geib S, Rochat H, Darbon H, Devaux C, Sabatier JM, DeWaard M.

FEBS Lett 489 202-207 PMID:11165250
Revisiting the specificity of mamestra brassicae and antheraea polyphemus pheromone binding proteins with a fluorescence binding assay (2001)

Campanacci V, Krieger J, Bette S, Sturgis JN, Lartigue A, Cambillau C, Breer H, Tegoni M.

J Biol Chem 276 20078-20084 PMID:11274212
Recognition of antigens by single-domain antibody fragments: the superfluous luxury of paired domains. (2001)

Muyldermans S, Cambillau C, Wyns L.

Trends Biochem Sci 26 230-235 PMID:11295555
The importance of framework residues h6, h7 and h10 in antibody heavy chains: experimental evidence for a new structural subclassification of antibody v(h) domains. (2001)

Jung S, Spinelli S, Schimmele B, Honegger A, Pugliese L, Cambillau C, Pluckthun A.

J Mol Biol 309 701-716 PMID:11397090
Selection, characterization and x-ray structure of anti-ampicillin single-chain fv fragments from phage-displayed murine antibody libraries. (2001)

Burmester J, Spinelli S, Pugliese L, Krebber A, Honegger A, Jung S, Schimmele B, Cambillau C, Pluckthun A.

J Mol Biol 309 681-695 PMID:11397088
Lateral Recognition of a Dye Hapten by a Llama VHH Domain (2001)

Spinelli S, Tegoni M,Frenken L,van Vliet C, Cambillau C.

J Mol Biol 311 123-129 PMID:11469862
Chemosensory Protein (CSP2) from the moth Mamestra brassicae: Expression and Secondary Structure from 1H and 15N NMR (2001)

Campanacci V,Mosbah A,Bornet O,Wechselberger R,Jacquin-Joly E,Cambillau C, Darbon H, Tegoni M.

Eur J Biochem 268 4731-4739 PMID:11532009
Complexation of two proteic insect inhibitors to chymotrypsin's active site suggests decoupled roles for binding and selectivity. (2001)

Roussel A, Mathieu M, Dobbs A, Luu B, Cambillau C, Kellenberger C..

J Biol Chem 276 38893-38898 PMID:11495915
Domain Swing Upon His to Ala Mutation in Nitrite Reductase of Pseudomonas aeruginosa. (2001)

Brown K, Roig-Zamboni V, Cutruzzola' F, Arese M, Sun W, Brunori M, Cambillau C, Tegoni M..

J Mol Biol 312 541-554 PMID:11563915
Solution Structure of Ptu1, a Toxin from the Assassin Bug Peirates turpis That Blocks the Voltage-Sensitive Calcium Channel N-Type (2001)

Bernard C,Corzo G, Mosbah A,Nakajima T, Darbon H.

Biochemistry 40 12795 -12800 PMID:11669615
Structural basis for alpha-K toxin specificity for K+ channels revealed through the solution 1H NMR structures of two noxiustoxin-iberiotoxin chimeras. (2001)

Ferrat G, Bernard C, Fremont V, Mullmann TJ, Giangiacomo KM, Darbon H.

Biochemistry 40 10998-1006 PMID:11551195
The location of the ligand binding site of carbohydrate binding modules that have evolved from a common sequence is not conserved (2001)

Czjzek M, Bolam DN, Mosbah A, Allouch J, Fontes CMGA, Ferreira LMA, Bornet O, Zamboni V, Darbon H, Smith N, Black GW, Henrissat B, Gilbert HJ.

J Biol Chem 276 48580-48587 PMID:11673472
Streptomyces matensis laminaripentaose hydrolase is an inverting b-1,3-glucanase (2001)

Nishimura T, Bignon C, Allouch J, Czjzek M, Darbon H, Watanabe T, Henrissat B.

FEBS Lett 499 187-90 PMID:11418137
Thermal Unfolding of a Llama Antibody Fragment: A Two-State Reversible Process. (2001)

Perez JM, Renisio JG, Prompers JJ, van Platerink CJ, Cambillau C, Darbon H, Frenken LG..

Biochemistry 40 74-83 PMID:11141058

2000

Generating a high-affinity scorpion-toxin receptor in KcsA-Kv1.3 (2000)

Legros C, Pollmann V, Knaus HG, Farrell AM, Darbon H, Bougis PE, Martin-Eauclaire MF and Pongs O.

J Biol Chem 275 16918-16924 PMID:10828071
Solution structure of BmKTX, a K+ blocker toxin from the chinese scorpion Buthus martensi (2000)

Renisio JG, Romi-Lebrun R, Blanc E, Bornet O, Nakajima T and Darbon H.

Proteins 38 70-78 PMID:10651040
Synthesis, 1H-NMR structure and activity of a three disulphide-bridged maurotoxin analog designed to restore the consensus motif of scorpion toxins. (2000)

Fajloun Z, Ferrat G, Carlier E, Lecomte C, Sandoz G, di Luccio E, Mabrouk K, Legros C, Darbon H, Rochat H, Sabatier JM and de Waard M.

J Biol Chem 275 13605-13612 PMID:10788477
Camelid heavy-chain variable domains provide efficient combining sites to haptens. (2000)

Spinelli S, Frenken LG, Hermans P, Verrips T, Brown K, Tegoni M, Cambillau C.

Biochemistry 39 1217-1222 PMID:10684599
Purification, characterization and preliminary crystallographic study of Coppe-containing Nitrous oxide reductase from Pseudomonas nautica 617 (2000)

Prudencio M, Pereira AS, Tavares P, Besson S, Cabrito I, Brown K, Samyn B, Devreese B, Van Beeumen J, Rusnak F, Fauque G, Moura JJG, Tegoni M, Cambillau C and Moura I.

Biochemistry 39 3899-3907 PMID:10747777
A new fold in the scorpion toxin, associated with an activity on a ryanodine-sensitive calcium channel (2000)

Mosbah A, Kharrat R, Fajloun Z, Renisio JG,Blanc E, Sabatier JM, El ayeb M, Darbon H.

Proteins 40 436-442 PMID:10861934
Maurotoxin and the Kv1.1 channel: voltage-dependent binding upon enantiomerization of the scorpion toxin disulfide bridge Cys31-Cys34. (2000)

Lecomte C, Ben Khalifa R, Martin-Eauclaire MF, Kharrat R, El Ayeb M, Darbon H, Rochat H, Crest M, Sabatier JM..

J Pept Res 55 246-254 PMID:10727107
Toxines animales et canaux ioniques (2000)

Darbon H.

J Soc Biol 193 445-450 PMID:10783702
Mammalian Odorant Binding Proteins (2000)

Tegoni M, Pelosi P, Vincent F, Spinelli S, Campanacci V, Grolli S, Ramoni R, Cambillau C.

Biochim Biophys Acta 1482 229-240 PMID:11058764
Complexes of Porcine Odorant Binding Protein with Odorant Molecules Belonging to Different Chemical Classes (2000)

Vincent F, Spinelli S, Ramoni R, Grolli S, Pelosi P, Cambillau C, Tegoni M.

J Mol Biol 300 127-139 PMID:10864504
Solution structure of HpTX2, a toxin from Heteropoda venatoria spider that blocks Kv4.2 potassium channel (2000)

Bernard C, Legros C, Ferrat G, Bischoff U, Marquardt A, Pongs O and Darbon H..

Prot Sci 9 2059-2067 PMID:11152117
Structural basis of sialyltransferase activity in trypanosomal sialidases. (2000)

Buschiazzo A, Tavares GA, Campetella O, Spinelli S, Cremona ML, Paris G, Amaya MF, Frasch AC, Alzari PM.

EMBO J 19 16-24 PMID:10619840
Digestive lipases: From three-dimensional structure to physiology. (2000)

Miled N, Canaan S, Dupuis L, Roussel A, Riviere M, Carriere F, de Caro A, Cambillau C, Verger R.

Biochimie 82 973-986 PMID:11099794
Structural and Genomic Correlates of Hyperthermostability. (2000)

Cambillau C, Claverie JM.

J Biol Chem 275 32383-32386 PMID:10940293
Maurotoxin vs Pi1/HsTx1 scorpion toxins: Towards new insights in the understanding of their distinct disulfide bridge patterns. (2000)

Fajloun Z, Mosbah A, Carlier E, Mansuelle P, Sandoz G, Fathallah M, di Luccio E, Devaux C, Rochat H, Darbon H, De Waard M, Sabatier JM.

J Biol Chem 275 39394-39402 PMID:10970898
Protein Engineering in Industrial Biotechnology (2000)

Longhi S, Nicolas A, Jelsch C, Cambillau C.

Editor/ Lilia Alberghina, Harwoo Academics Publishers, Amsterdam 75-113 PMID:0
Revisiting the Catalytic CuZ Cluster of Nitrous Oxide (N2O) Reductase: Evidence of a Bridging Inorganic Sulphur. (2000)

Brown K, Djinovic-Carugo K, Haltia T, Cabrito I, Saraste M, Moura JJ, Moura I, Tegoni M, Cambillau C.

J Biol Chem 275 41133-41136 PMID:11024061
Structure/Function Studies of Mammalian Digestive Lipases (2000)

Roussel A, Whiters-Martinez C, Canaan S, Carrière F, Verger R, Cambillau C..

Lipases and Lipids: Structure, function and biotechnological applications, edited by Kokotos G., Crete University Press, Greece PMID:0
Crystal structure of a cohesin domain from Clostridium cellulolyticum : implications for the dockerin recognition (2000)

Spinelli S, Fierobe HP, Belaich A, Belaich JP, Henrissat B, Cambillau C.

J Mol Biol 304 189-200 PMID:11080455
Pharmacology of small conductance Ca2+ activated K+ channels (2000)

Blanc E, Darbon H.

In Potassium channels in cardiovascular biology (Archer,S. and Rusch,N. eds) Kluwer Publishers 235-256 PMID:0
A Novel Type of Catalytic Copper Cluster in Nitrous Oxide Reductase (2000)

Brown K, Tegoni M, Prudencio M, Pereira AS, Besson S, Moura JJ, Moura I and Cambillau C.

Nat Struct Biol 7 191-5 PMID:10700275
Solution structure of the module X2_1 of unknown function of the cellulosomal scaffolding Protein CipC of Clostridum cellulolyticum (2000)

Mosbah A, Belaich A, Bornet O, Belaich JP, Henrissat B, Darbon H.

J Mol Biol 304 201-217 PMID:11080456

1999

Crystal structure of the bovine beta4galactosyltransferase catalytic domain alone or in the presence of the substrate donor, uridine diphosphogalactose (1999)

Gastinel L, Cambillau C, Bourne Y.

EMBO J 18 3546-3557 PMID:10393171
Insight in odorant perception: The crystal structure and binding characteristics of antibody fragments directed against the musk odorant traseolide (1999)

Langedijk A C, Spinelli S, Anguille C, Hermans P, Nederlof J, Butenandt J, Honegger AM, Cambillau C, Pluckthun A. .

J.Mol.Biol. 292 855-869 PMID:10525411
Recombinant Pheromone Binding Protein 1 from Mamestra brassicae (MbraPBP 1): functional and structural characterisation (1999)

Campanacci V, Longhi S, Nagnan-Le Meillour P, Cambillau C, Tegoni M.

Eur J Biochem 264 707-716 PMID:10491116
Crystal structure of a ternary complex between human Chorionic Gonadotropin (hCG) and two Fv fragments specific for the ?- and ?-subunits (1999)

Tegoni M, Spinelli S, Verhoeyen M, Davis P, Cambillau C.

J Mol Biol 289 1375-1385 PMID:10373373
Crystal Structure of the Bifunctional N-Acetylglucosamine 1-Phosphate Uridyltransferase from E.coli: A Paradigm for the related pyrophosphorylase superfamily (1999)

Brown K, Pompeo F, Dixon S, Mengin-Lecreux D, Cambillau C, Bourne Y.

EMBO J 18 4096-107 PMID:10428949
MAD Structure of Pseudomonas nautica Cytochrome c552 Mimicks the Domain's Association in the c4 Dihemic Cytochrome (1999)

Brown K, Nurizzo D, Besson S, Shepard W, Moura J, Moura I, Tegoni M, Cambillau C.

J Mol Biol 289 1017-1028 PMID:10369779
Crystal structure of human gastric lipase and model of lysosomal acid lipase, two lipolytic enzymes of medical interest (1999)

Roussel A, Canaan S, Egloff MP, Rivière M, Dupuis L, Verger R, Cambillau C. .

J Biol Chem 274 16995-17002 PMID:10358049
Does the reduction of c heme trigger the conformational change of crystalline nitrite reductase? (1999)

Nurizzo D, Cutruzzola F, Arese M, Bourgeois D, Brunori M, Cambillau C, Tegoni M.

J Biol Chem 274 14997-5004 PMID:10329702
The structure of an entire noncovalent immunoglobulin Kappa light-chaindimer (Bence-Jones protein) reveals a weak and unusual constant domains association. (1999)

Roussel A, Spinelli S, Deret S, Navaza J, Aucouturier P, Cambillau C..

Eur J Biochem 260 192-9 PMID:10091599
Solution structure of potassium channel inhibiting scorpion toxin Lq2. (1999)

Renisio JG, Lu Z, Blanc E, Jin W, Lewis JH, Bornet O and Darbon H..

Proteins 34 417-426 PMID:10081954
Gastric lipase: Crystal Structure and Activity. (1999)

Canaan S, Roussel A, Verger R and Cambillau C.

Biochim Biophys Acta 1441 197-204 PMID:10570247
Structure-activity of cutinase, a small lipolytic enzyme. (1999)

Longhi S and Cambillau C.

Biochim Biophys Acta 1441 185-96 PMID:10570246
Colipase: structure and interaction with pancreatic lipase (1999)

van Tilbeurgh H, Bezzine S, Cambillau C, Verger R, Carrière F. .

Biophys Biochem Acta 1441 173-84 PMID:10570245
Chemical synthesis and structure-activity relationships of TsKapa, a novel scorpion toxin acting on apamin-sensitive SK channel (1999)

Lecomte C, Ferrat G, Fajloun Z, van Rietschoten J, Rochat H, Martin-Eauclaire MF, Darbon H, Sabatier JM.

J.Peptide Res 54 369-376 PMID:10563502
Three Dimensional Structure of Scorpion Toxins: Towards a new model of interaction with potassium Channels (1999)

Darbon H, Blanc E, Sabatier JM.

In Perspective in Drug Discovery and Design, Darbon, Sabatier eds., Kluwer Publishers 16 41-60 PMID:0
Vers une compréhension structurale de la chaine de denitrification chez Pseudomonas (1999)

Tegoni M, Nurizzo D, Brown K, Zamboni V, Spinelli S, Campanacci V, Vincent F, Diotallevi S, Cambillau C.

Regard sur la Biochimie 4 35-41 PMID:0
Redox Potential (1999)

Tegoni M and Cambillau C.

Encyclopedia of Molecular Biology 1736-1737 PMID:0
Redox Enzymes (1999)

Tegoni M and Cambillau C.

Encyclopedia of Molecular Biology 2112-2117 PMID:0
The Role of the Alpha-K Toxin Peptide Backbone Structures in Defining Maxi-K Channel Specificity (1999)

Fremont V, Mullmann TJ, Blanc E, Darbon H, Giangiacomo KM.

Biophys J 76(1) A333-A333 PMID:0

1998

Messages from ultrahigh resolution crystal structures (1998)

Longhi S, Czjzek M, Cambillau C..

Curr. Opin. Struct. Biol. 8 730-7 PMID:9914254
Molecular cloning and bacterial expression of a general odorant-binding protein from the cabbage armyworm Mamestra brassicae. (1998)

Maibeche-Coisne M, Longhi S, Jacquin-Joly E, Brunel C, Egloff MP, Gastinel L, Cambillau C, Tegoni M, Nagnan-Le Meillour P.

Eur J Biochem 258(2) 768-74 PMID:9874246
Kinetics and interaction studies between cytochrome c3 and Fe-only hydrogenase from Desulfovibrio vulgaris Hildenborough. (1998)

Brugna M, Giudici-Orticoni MT, Spinelli S, Brown K, Tegoni M, Bruschi M.

Proteins 33(4) 590-600 PMID:9849942
Structure and activity of rat pancreatic lipase-related protein 2 (1998)

Roussel A, Yang Y, Ferrato F, Verger R, Cambillau C, Lowe M.

J Biol Chem 273(48) 32121-8 PMID:9822688
Structural basis for the substrate selectivity of pancreatic lipases and some related proteins. (1998)

Carriere F, Withers-Martinez C, van Tilbeurgh H, Roussel A, Cambillau C, Verger R.

Biochim Biophys Acta 1376(3) 417-432 PMID:9805004
Conformational changes occurring upon reduction and NO binding in nitrite reductase from pseudomonas aeruginosa (1998)

Nurizzo D, Cutruzzola F, Arese M, Bourgeois D, Brunori M, Cambillau C, Tegoni M.

Biochemistry 37(40) 13987-96 PMID:9760233
Temperature-jump and potentiometric studies on recombinant wild type and Y143F and Y254F mutants of Saccharomyces cerevisiae flavocytochrome b2: role of the driving force in intramolecular electron transfer kinetics. (1998)

Tegoni M, Silvestrini MC, Guigliarelli B, Asso M, Brunori M, Bertrand P.

Biochemistry 37(37) 12761-71 PMID:9737853
Solution Structure of Two New Toxins from the Venom of the Chinese Scorpion Buthus martensi Karsch Blockers of Potassium Channels. (1998)

Blanc E, Romi-Lebrun R, Bornet O, Nakajima T, Darbon H.

Biochemistry 37(36) 12412-8 PMID:9730813
Reactivation of the totally inactive pancreatic lipase RP1 by structure- predicted point mutations (1998)

Roussel A, de Caro, Bezzine S, Gastinel L, de Caro, Carriere F, Leydier S, Verger R, Cambillau C.

Proteins 32(4) 523-31 PMID:9726421
Retroviral envelope glycoprotein processing: structural investigation of the cleavage site (1998)

Moulard M, Chaloin L, Canarelli S, Mabrouk K, Darbon H.

Biochemistry 37(27) 9870 PMID:9657701
The structure of the monomeric porcine odorant binding protein sheds light on the domain swapping mechanism. (1998)

Spinelli S, Ramoni R, Grolli S, Bonicel J, Cambillau C, Tegoni M.

Biochemistry 37(22) 7913-8 PMID:9609684
Packing forces in nine crystal forms of cutinase. (1998)

Jelsch C, Longhi S, Cambillau C.

Proteins 31(3) 320-33 PMID:9593202
Retroviral envelope glycoprotein processing: structural investigation of the cleavage site [published erratum appears in Biochemistry 1998 Jul 7;37(27):9870] (1998)

Moulard M, Chaloin L, Canarelli S, Mabrouk K, Darbon H.

Biochemistry 37(13) 4510-7 PMID:9521771
An Integration Routine Based on Profile Fitting with Optimized Fitting Area for the Evaluation of Weak and/or Overlapped Two-Dimensional Laue or Monochromatic Patterns (1998)

Bourgeois D, Nurizzo D, Kahn R, Cambillau C.

Appl.Cryst. 31 22-35 PMID:0
Structure-Function relationships of pancreatic lipases. (1998)

Carriere F Withers-Martinez C, van Tilbeurgh H, Roussel A, Cambillau C, Verger R..

Fett/Lipid 100 96-102 PMID:0
Pancreatic lipases and their complexes with colipases and inhibitors: Crystallization and crystal packing (1998)

Cambillau C, Bourne Y, Egloff MP, Martinez C, van Tilbeurgh H.

Methods in Enzymology 284 107-119 PMID:0

1997

Structure of a pancreatic a-amylase bound to a substrate analogue at 2.03 A resolution. (1997)

Qian M, Spinelli S, Driguez H, Payan F.

Protein Sci 6(11) 2285-96 PMID:9385631
Solution structure of TsKapa, a charybdotoxin-like scorpion toxin from Tityus serrulatus with high affinity for apamin-sensitive Ca(2+)- activated K+ channels. (1997)

Blanc E, Lecomte C, Rietschoten JV, Sabatier JM, Darbon H.

Proteins 29(3) 359-69 PMID:9365990
Solution structure of maurotoxin, a scorpion toxin from Scorpio maurus, with high affinity for voltage-gated potassium channels. (1997)

Blanc E, Sabatier JM, Kharrat R, Meunier S, el Ayeb, Van Rietschoten, Darbon H.

Proteins 29(3) 321-33 PMID:9365987
Pancreatic lipases and their complexes with colipases and inhibitors: crystallization and crystal packing. (1997)

Cambillau C, Bourne Y, Egloff MP, Martinez C, van Tilbeurgh.

Methods Enzymol 284(0) 107-19 PMID:9379929
N-terminal arm exchange is observed in the 2.15 A crystal structure of oxidized nitrite reductase from Pseudomonas aeruginosa. (1997)

Nurizzo D, Silvestrini MC, Mathieu M, Cutruzzola F, Bourgeois D, Fulop V, Hajdu J, Brunori M, Tegoni M, Cambillau C.

Structure 5(9) 1157-71 PMID:9331415
1H-NMR-derived secondary structure and overall fold of a natural anatoxin from the scorpion Androctonus australis hector. (1997)

Blanc E, Hassani O, Meunier S, Mansuelle P, Sampieri F, Rochat H, Darbon H.

Eur J Biochem 247(3) 1118-26 PMID:9288938
Differential involvement of disulfide bridges on the folding of a scorpion toxin. (1997)

Calabro V, Sabatier JM, Blanc E, Lecomte C, Van Rietschoten, Darbon H.

J Pept Res 50(1) 39-47 PMID:9273886
Resonance Raman study on the oxidized and anionic semiquinone forms of flavocytochrome b2 and L-lactate monooxygenase. Influence of the structure and environment of the isoalloxazine ring on the flavin function. (1997)

Tegoni M, Gervais M, Desbois A.

Biochemistry 36(29) 8932-46 PMID:9220981
Atomic resolution (1.0 A) crystal structure of Fusarium solani cutinase: stereochemical analysis. (1997)

Longhi S, Czjzek M, Lamzin V, Nicolas A, Cambillau C.

J Mol Biol 268(4) 779-99 PMID:9175860
Determination of the three-dimensional structure of CC chemokine monocyte chemoattractant protein 3 by 1H two-dimensional NMR spectroscopy [published erratum appears in Biochemistry 1997 Aug 26;36(34):10600] (1997)

Meunier S, Bernassau JM, Guillemot JC, Ferrara P, Darbon H.

Biochemistry 36(15) 4412-22 PMID:9109648
Crystal structure of cutinase covalently inhibited by a triglyceride analogue. (1997)

Longhi S, Mannesse M, Verheij HM, De Haas, Egmond M, Knoops-Mouthuy E, Cambillau C.

Protein Sci 6(2) 275-86 PMID:9041628
Pancreatic lipase structure-function relationships by domain exchange. (1997)

Carriere F, Thirstrup K, Hjorth S, Ferrato F, Nielsen PF, Withers-Martinez C, Cambillau C, Boel E, Thim L, Verger R.

Biochemistry 36(1) 239-48 PMID:8993339
Dipole moments of scorpion toxins direct the interaction towards small- of large-conductance Ca2+-activated K+ channels. (1997)

Fremont V, Blanc E, Crest M, Martin-Eauclaire, MF, Gola M, Darbon H and Van Rietschoten J..

LIPS 4 305-312 PMID:0
Accuracy of structural information obtained at the ESRF from very rapid Laue data collection on macromolecules (1997)

Bourgeois D, Longhi S, Wulff M, Cambillau C.

J.Appl.Cryst. 30 153-163 PMID:0

1996

A pancreatic lipase with a phospholipase A1 activity: crystal structure of a chimeric pancreatic lipase-related protein 2 from guinea pig. (1996)

Withers-Martinez C, Carriere F, Verger R, Bourgeois D, Cambillau C.

Structure 4 1363-74 PMID:8939760
Domain swapping creates a third putative combining site in bovine odorant binding protein dimer (1996)

Tegoni M, Ramoni R, Bignetti E, Spinelli S, Cambillau C.

Nat Struct Biol 3 863-867 PMID:8836103
The crystal structure of a llama heavy chain variable domain [letter] (1996)

Spinelli S, Frenken L, Bourgeois D, de Ron, Bos W, Verrips T, Anguille C, Cambillau C, Tegoni M.

Nat Struct Biol 3 752-757 PMID:8784347
Synthesis and characterization of leiurotoxin I analogs lacking one disulfide bridge: evidence that disulfide pairing 3-21 is not required for full toxin activity. (1996)

Sabatier JM, Lecomte C, Mabrouk K, Darbon H, Oughideni R, Canarelli S, Rochat H, Martin-Eauclaire MF, van Rietschoten.

Biochemistry 35 10641-7 PMID:8718853
Crystallization and Preliminary X-Ray Study of the 8-amino-7-oxopelargonate Synthase from Bacillus sphaericus (1996)

Spinelli S, Ploux O, Marquet A, Anguille C, Jelsch C, Cambillau C, Martinez C.

Acta Crystallogr D Biol Crystallogr 52 866-868 PMID:0
Chemical synthesis and characterization of maurotoxin, a short scorpion toxin with four disulfide bridges that acts on K+ channels. (1996)

Kharrat R, Mabrouk K, Crest M, Darbon H, Oughideni R, Martin-Eauclaire MF, Jacquet G, el Ayeb, Van Rietschoten, Rochat H, Sabatier JM.

Eur J Biochem 242(3) 491-8 PMID:9022673
Dynamics of Fusarium solani cutinase investigated through structural comparison among different crystal forms (1996)

Longhi S, Nicolas A, Creveld L, Egmond M, Verrips CT, de Vlieg J, Martinez C, Cambillau C.

Proteins 26 442-458 PMID:8990497
Characterization of PO1, a new peptide ligand of the apamin-sensitive Ca2+ activated K+ channel. (1996)

Zerrouk H, Laraba-Djebari F, Fremont V, Meki A, Darbon H, Mansuelle P, Oughideni R, van Rietschoten, Rochat H, Martin-Eauclaire MF.

Int J Pept Protein Res 48(6) 514-21 PMID:8985784
Acyl glycerol hydrolases: inhibitors, interface and catalysis. (1996)

Cambillau C, Longhi S, Nicolas A, Martinez C.

Curr Opin Struct Biol 6(4) 449-55 PMID:8794161
Characterization of a new peptide from Tityus serrulatus scorpion venom which is a ligand of the apamin-binding site. (1996)

Legros C, Oughuideni R, Darbon H, Rochat H, Bougis PE, Martin-Eauclaire MF.

FEBS Lett 390(1) 81-4 PMID:8706835
Crystal structure of pig pancreatic a-amylase isoenzyme II, in complex with the carbohydrate inhibitor acarbose. (1996)

Gilles C, Astier JP, Marchis-Mouren G, Cambillau C, Payan F.

Eur J Biochem 238(2) 561-9 PMID:8681972
Solution structure of P01, a natural scorpion peptide structurally analogous to scorpion toxins specific for apamin-sensitive potassium channel. (1996)

Blanc E, Fremont V, Sizun P, Meunier S, Van Rietschoten, Thevand A, Bernassau JM, Darbon H.

Proteins 24(3) 359-69 PMID:8778783
Contribution of cutinase serine 42 side chain to the stabilization of the oxyanion transition state. (1996)

Nicolas A, Egmond M, Verrips CT, de Vlieg, Longhi S, Cambillau C, Martinez C.

Biochemistry 35(2) 398-410 PMID:8555209

1993

Solution structure of P05-NH2, a scorpion toxin analog with high affinity for the apamin-sensitive potassium channel. (1993)

Meunier S, Bernassau JM, Sabatier JM, Martin-Eauclaire MF, Van Rietschoten, Cambillau C, Darbon H.

Biochemistry 32(45) 11969-76 PMID:8218272

1992

Solution conformation of human neuropeptide Y by 1H nuclear magnetic resonance and restrained molecular dynamics. (1992)

Darbon H, Bernassau JM, Deleuze C, Chenu J, Roussel A, Cambillau C.

Eur J Biochem 209 765-71 PMID:1425680

1990

Three-dimensional structures of complexes of Lathyrus ochrus isolectin I with glucose and mannose: fine specificity of the monosaccharide-binding site. (1990)

Bourne Y, Roussel A, Frey M, Rouge P, Fontecilla-Camps JC, Cambillau C.

Proteins 8 365-76 PMID:2091026
Conformational flexibility of a scorpion toxin active on mammals and insects: a circular dichroism study. (1990)

Loret EP, Sampieri F, Roussel A, Granier C, Rochat H.

Proteins 8 164-72 PMID:2235994