Publications

2022

2022
Experimental Evidence of Intrinsic Disorder and Amyloid Formation by the Henipavirus W Proteins

Giulia Pesce, Frank Gondelaud, Denis Ptchelkine, Juliet Nilsson, Christophe Bignon, Jérémy Cartalas, Patrick Fourquet, Sonia Longhi

International Journal of Molecular Sciences 23:923 (2022)10.3390/ijms23020923

2021

2021
Identification of a Region in the Common Amino-terminal Domain of Hendra Virus P, V, and W Proteins Responsible for Phase Transition and Amyloid Formation

Edoardo Salladini, Frank Gondelaud, Juliet Nilsson, Giulia Pesce, Christophe Bignon, Maria Grazia Murrali, Roxane Fabre, Roberta Pierattelli, Andrey Kajava, Branka Horvat, Denis Gerlier, Cyrille Mathieu, Sonia Longhi

Biomolecules 11:1324 (2021)10.3390/biom11091324

2021
Structural and dynamics analysis of intrinsically disordered proteins by high-speed atomic force microscopy

Noriyuki Kodera, Daisuke Noshiro, Sujit Dora, Tetsuya Mori, Johnny Habchi, David Blocquel, Antoine Gruet, Marion Dosnon, Edoardo Salladini, Christophe Bignon, Yuko Fujioka, Takashi Oda, Nobuo Noda, Mamoru Sato, Marina Lotti, Mineyuki Mizuguchi, Sonia Longhi, Toshio Ando

Nature Nanotechnology 16:181-189 (2021)10.1038/s41565-020-00798-9

2019

2019
Binding induced folding: Lessons from the kinetics of interaction between NTAIL and XD

Angelo Toto, Francesca Troilo, Lorenzo Visconti, Francesca Malagrinò, Christophe Bignon, Sonia Longhi, Stefano Gianni

Archives of Biochemistry and Biophysics 671:255-261 (2019)10.1016/j.abb.2019.07.011

2019
An arsenal of methods for the experimental characterization of intrinsically disordered proteins – How to choose and combine them?

Antoine Schramm, Christophe Bignon, Stefania Brocca, Rita Grandori, Carlo Santambrogio, Sonia Longhi

Archives of Biochemistry and Biophysics 108055 (2019)10.1016/j.abb.2019.07.020

2019
Understanding Intramolecular Crosstalk in an Intrinsically Disordered Protein

Francesca Troilo, Daniela Bonetti, Christophe Bignon, Sonia Longhi, Stefano Gianni

ACS Chemical Biology 14:337-341 (2019)10.1021/acschembio.8b01055

2019
Modulation of Measles Virus NTAIL Interactions through Fuzziness and Sequence Features of Disordered Binding Sites

Christophe Bignon, Francesca Troilo, Stefano Gianni, Sonia Longhi

Biomolecules 9:8 (2019)10.3390/biom9010008

2018

2018
InSiDDe: A Server for Designing Artificial Disordered Proteins

Antoine Schramm, Philippe Lieutaud, Stefano Gianni, Sonia Longhi, Christophe Bignon

International Journal of Molecular Sciences 19:e91 (2018)10.3390/ijms19010091

2017

2017
Partner-Mediated Polymorphism of an Intrinsically Disordered Protein

Christophe Bignon, Francesca Troilo, Stefano Gianni, Sonia Longhi

Journal of Molecular Biology (2017)10.1016/j.jmb.2017.11.012

2016

2016
Modulation of Re-initiation of Measles Virus Transcription at Intergenic Regions by PXD to NTAIL Binding Strength

Louis-Marie Bloyet, Joanna Brunel, Marion Dosnon, Véronique Hamon, Jenny Erales, Antoine Gruet, Carine Lazert, Christophe Bignon, Philippe Roche, Sonia Longhi, Denis Gerlier

PLoS Pathogens 12:e1006058 (2016)10.1371/journal.ppat.1006058

2016
Modulation of Re-initiation of Measles Virus Transcription at Intergenic Regions by PXD to NTAIL Binding Strength

Louis-Marie Bloyet, Joanna Brunel, Marion Dosnon, Véronique Hamon, Jenny Erales, Antoine Gruet, Carine Lazert, Christophe Bignon, Philippe Roche, Sonia Longhi, Denis Gerlier

PLoS Pathogens 12:e1006058 (2016)10.1371/journal.ppat.1006058

2016
Fuzzy regions in an intrinsically disordered protein impair protein-protein interactions

Antoine Gruet, Marion Dosnon, David Blocquel, Joanna Brunel, Denis Gerlier, Rahul K. Das, Daniela Bonetti, Stefano Gianni, Monika Fuxreiter, Sonia Longhi, Christophe Bignon

FEBS Journal 283:576-594 (2016)10.1111/febs.13631

2015

2015
Recombinant protein production facility for fungal biomass-degrading enzymes using the yeast Pichia pastoris

Mireille Haon, Sacha Grisel, David Navarro, Antoine Gruet, Jean-Guy Berrin, Christophe Bignon

Frontiers in Microbiology 6 (2015)10.3389/fmicb.2015.01002

2013

2013
Dissecting Partner Recognition by an Intrinsically Disordered Protein Using Descriptive Random Mutagenesis

Antoine Gruet, Marion Dosnon, Andrea Vassena, Vincent Lombard, Denis Gerlier, Christophe Bignon, Sonia Longhi

Journal of Molecular Biology 425:3495-3509 (2013)10.1016/j.jmb.2013.06.025

2012

2012
Single pH buffer refolding screen for protein from inclusion bodies

Bruno Coutard, Etienne Danchin, Rachid Oubelaid, Bruno Canard, Christophe Bignon

Protein Expression and Purification 82:352-359 (2012)10.1016/j.pep.2012.01.014

2010

2010
Automated assay for screening the enzymatic release of reducing sugars from micronized biomass

David Navarro, Marie Couturier, Gabriela Ghizzi Damasceno da Silva, Jean-Guy Berrin, Xavier Rouau, Marcel Asther, Christophe Bignon

Microbial Cell Factories 9:12 p. (2010)10.1186/1475-2859-9-58

2009

2009
Interaction between the SifA Virulence Factor and Its Host Target SKIP Is Essential for Salmonella Pathogenesis

Lautaro Diacovich, Audrey Dumont, Daniel Lafitte, Elodie Soprano, Aude-Agnès Guilhon, Christophe Bignon, Jean-Pierre Gorvel, Yves Bourne, Stéphane Méresse

Journal of Biological Chemistry 284:33151-33160 (2009)10.1074/jbc.m109.034975

2009
Interaction between the sifa virulence factor and its host target skip is essential for salmonella pathogenesis.

Lautaro Diacovich, Audrey Dumont, Daniel Lafitte, Elodie Soprano, Aude-Agnes Guilhon, Christophe Bignon, Jean-Pierre Gorvel, Yves Bourne, Stephane Meresse

Journal of Biological Chemistry epub ahead of print (2009)10.1074/jbc.M109.034975

2007

2007
Expression in Escherichia coli, refolding and crystallization of Aspergillus niger feruloyl esterase A using a serial factorial approach

Isabelle Benoit, Bruno Coutard, Rachid Oubelaid, Marcel Asther, Christophe Bignon

Protein Expression and Purification 55:166-174 (2007)10.1016/j.pep.2007.04.001

2006

2006
Respective importance of protein folding and glycosylation in the thermal stability of recombinant feruloyl esterase A

Isabelle Benoit, Michèle Asther, Gerlind Sulzenbacher, Eric Record, Laurence Marmuse, Goetz Parsiegla, Isabelle Gimbert, Marcel Asther, Christophe Bignon

FEBS Letters 580:5815-5821 (2006)10.1016/j.febslet.2006.09.039

2004

2004
The Three-dimensional Structure of Invertase (β-Fructosidase) from Thermotoga maritima Reveals a Bimodular Arrangement and an Evolutionary Relationship between Retaining and Inverting Glycosidases

Francois Alberto, Christophe Bignon, Gerlind Sulzenbacher, Bernard Henrissat, Mirjam Czjzek

Journal of Biological Chemistry 279:18903-18910 (2004)10.1074/jbc.M313911200

2004
Crystal Structure of Thermotoga maritima ␣-L-Fucosidase INSIGHTS INTO THE CATALYTIC MECHANISM AND THE MOLECULAR BASIS FOR FUCOSIDOSIS

Gerlind Sulzenbacher, Christophe Bignon, Takeshi Nishimura, Chris Tarling, Stephen Withers, Bernard Henrissat, Yves Bourne

Journal of Biological Chemistry (2004)10.1074/jbc.M313783200

2004
The Escherichia coli YadB Gene Product Reveals a Novel Aminoacyl-tRNA Synthetase Like Activity

Valérie Campanacci, Daniel Y. Dubois, Hubert Becker, Daniel Kern, Silvia Spinelli, Christel Valencia, Fabienne Pagot, Aurelia Salomoni, Sacha Grisel, Renaud Vincentelli, Christophe Bignon, Jacques Lapointe, Richard Giege, Christian Cambillau

Journal of Molecular Biology 337:273-283 (2004)10.1016/j.jmb.2004.01.027

2003

2003
Identification of the Catalytic Nucleophile of the Family 29 α-L-Fucosidase from Thermotoga maritima through Trapping of a Covalent Glycosyl-Enzyme Intermediate and Mutagenesis

Chris Tarling, Shouming He, Gerlind Sulzenbacher, Christophe Bignon, Yves Bourne, Bernard Henrissat, Stephen Withers

Journal of Biological Chemistry (2003)10.1074/jbc.M306610200

2003
Medium-Scale Structural Genomics: Strategies for Protein Expression and Crystallization

Renaud Vincentelli, Christophe Bignon, Arnaud Gruez, Stéphane Canaan, Gerlind Sulzenbacher, Mariella Tegoni, Rie Campanacci, Christian Cambillau

Accounts of Chemical Research (2003)10.1021/ar010130s

2002

2002
A medium-throughput crystallization approach

Gerlind Sulzenbacher, Arnaud Gruez, Véronique Roig-Zamboni, Silvia Spinelli, Christel Valencia, Fabienne Pagot, Renaud Vincentelli, Christophe Bignon, Aurelia Salomoni, Sacha Grisel, Damien Maurin, Céline Huyghe, Kent Johansson, Alice Grassick, Alain Roussel, Yves Bourne, Sophie Perrier, Linda Miallau, Phillippe Cantau, Eric Blanc, Michel Genevois, Alain Grossi, André Zenatti, Valérie Campanacci, Christian Cambillau

Acta crystallographica Section D : Structural biology [1993-...] 58:2109-2115 (2002)10.1107/s0907444902013938

1998

1998
Cloning, preparation and characterization of biologically active recombinant caprine placental lactogen

E. Sakal, Christophe Bignon, N. Chapnik-Cohen, Nathalie Daniel-Carlier, Jacqueline Paly, L. Belair, Jean Djiane, A. Gertler

Journal of Endocrinology 159:509-518 (1998)10.1677/joe.0.1590509