The activity of the team revolves around a variety of subjects that require knowledge of a wealth of methods and technologies.
Our main objective is to characterize at biochemical level the molecules (proteins) involved in these processes, to define the way they interact and to study their tridimensional structure by X-ray crystallography.
Research projects in the “Structural Glycobiology & Neurobiology” team address the molecular architecture and functional mechanism of carbohydrate-active enzymes (CAZymes), sensors domains, lectins, and of enzymes, receptors and cell adhesion molecules with a neurobiological interest.
Our work, which aims at establishing the relationships between the aminoacid sequence of carbohydrate-active enzymes and their precise specificity, find developments in various areas, from the exploration of the gut microbiota to the search of novel enzymes for biofuel production or for the conversion of blood groups.
The team’s objective is to design and synthesize antiviral drugs against viruses for which there is no treatment and to design more effective antiviral drugs than those currently used in therapy.
The team focuses on the identification, characterization and elucidation of the functional role of disordered regions within proteins relevant in terms of human health.