Publications of the team

2020

1. Comparative mapping of selected structural determinants on the extracellular domains of cholinesterase-like cell-adhesion molecules (2020)
   Comoletti D, Trobiani L, Chatonnet A, Bourne Y, Marchot P.
   Neuropharmacol in press PMID:33166544
2. The neuroligins and the synaptic pathway in Autism Spectrum Disorder (2020)
   Trobiani L, Meringolo M, Diamanti T, Bourne Y, Marchot P, Martella G, Dini L, Pisani A, De Jaco A, Bonsi P.
   Neurosci Biobehav Rev 119 37-51 PMID:32991906
3. Biochemical characterization of a glycosyltransferase Gtf3 from Mycobacterium smegmatis: a case study of improved protein solubilization (2020)
   Bakli M, Karim L, Mokhtari-Soulimane N, Merzouk H, Vincent F.
   3 Biotech 10 436 PMID:32999813
4. The Ig-like domain of Punctin/MADD-4 is the primary determinant for interaction with the ectodomain of neuroligin NLG-1 (2020)
   Platsaki S, Zhou X, Pinan-Lucarre B, Delauzun V, Tu H, Mansuelle P, Fourquet P, Bourne Y, Bessereau J-L, Marchot P.
   J Biol Chem 295 16267-16279 PMID:32928959
5. Snapshots of ADP-ribose bound to Getah virus macro domain reveal an intriguing choreography (2020)
   Ferreira-Ramos AS, Sulzenbacher G, Canard B, Coutard B.
   Sci Rep 10 14422 PMID:32879358
6. Report from the 26th Meeting on Toxinology, "Bioengineering of Toxins", Organized by the French Society of Toxinology (SFET) and Held in Paris, France, 4-5 December 2019. (2020)
   Marchot P, Diochot S, Popoff MR, Benoit E.
   Toxins 12 31 (pp 1-30) PMID:31947870

2019

7. An evolutionary perspective on the first disulfide bond in members of the cholinesterase-carboxylesterase (COesterase) family: Possible outcomes for cholinesterase expression in prokaryotes. (2019)
   Chatonnet A, Brazzolotto X, Hotelier T, Lenfant N, Marchot P, Bourne Y.
   Chem Biol Interact 308 179-184 PMID:31100280
8. Substrate binding mode and catalytic mechanism of human heparan sulfate d-glucuronyl C5 epimerase. (2019)
   Debarnot C, Monneau YR, Roig-Zamboni V, Delauzun V, Le Narvor C, Richard E, Henault J, Goulet A, Fadel F, Vives RR, Priem B, Bonnaffe D, Lortat-Jacob H, Bourne Y.
   Proc Natl Acad Sci U S A 116 6760-6765 PMID:30872481
9. Overview of the Structure-Function Relationships of Mannose-Specific Lectins from Plants, Algae and Fungi. (2019)
   Barre A, Bourne Y, Van Damme EJM, Rouge P.
   Int J Mol Sci 20 254 PMID:30634645

2018

10. Genetic and enzymatic characterization of 3-O-sulfotransferase SNPs associated with Plasmodium falciparum parasitaemia. (2018)
    Nguyen NT, Vives RR, Torres M, Delauzun V, Saesen E, Roig-Zamboni V, Lortat-Jacob H, Rihet P, Bourne Y.
    Glycobiology 28 534-541 PMID:29718295
11. Lytic xylan oxidases from wood-decay fungi unlock biomass degradation. (2018)
    Couturier M, Ladeveze S, Sulzenbacher G, Ciano L, Fanuel M, Moreau C, Villares A, Cathala B, Chaspoul F, Frandsen KE, Labourel A, Herpoel-Gimbert I, Grisel S, Haon M, Lenfant N, Rogniaux H, Ropartz D, Davies GJ, Rosso MN, Walton PH, Henrissat B, Berrin JG.
    Nat Chem Biol 14 306-310 PMID:29377002

2017

12. Hot spots for protein partnership at the surface of cholinesterases and related alpha/beta hydrolase fold proteins or domains - a structural perspective. (2017)
    Bourne Y, Marchot P.
    Molecules 23 35 PMID:29295471
13. Ten years of CAZypedia: A living encyclopedia of carbohydrate-active enzymes. (2017)
    The CAZypedia Consortium.
    Glycobiology 28 3-8 PMID:29040563
14. Glycosylate and move! The glycosyltransferase Maf is involved in bacterial flagella formation. (2017)
    Sulzenbacher G, Roig-Zamboni V, Lebrun R, Guerardel Y, Murat D, Mansuelle P, Yamakawa N, Quian XX, Vincentelli R, Bourne Y, Wu LF, Alberto F.
    Environ Microbiol 20 228-240 PMID:29076618
15. Structure of human lysosomal acid alpha-glucosidase - a guide for the treatment of Pompe disease. (2017)
    Roig-Zamboni V, Cobucci-Ponzano B, Iacono R, Ferrara MC, Germany S, Bourne Y, Parenti G, Moracci M, Sulzenbacher G.
    Nat Commun 8 1111 PMID:29061980
16. Structural and functional insights into the periplasmic detector domain of the GacS histidine kinase controlling biofilm formation in Pseudomonas aeruginosa. (2017)
    Ali-Ahmad A, Fadel F, Sebban-Kreuzer C, Ba M, Pelissier GD, Bornet O, Guerlesquin F, Bourne Y, Bordi C, Vincent F.
    Sci Rep 7 11262 PMID:28900144
17. A Triad of Crystals Sheds Light on MDGA Interference with Neuroligation. (2017)
    Thoumine O, Marchot P.
    Neuron 95 729-732 PMID:28817794
18. Preface: Cholinergic Mechanisms. (2017)
    Prado MAM, Marchot P, Silman I.
    J Neurochem 142 Suppl 2 3-6 PMID:28791707
19. Toscana virus nucleoprotein oligomer organization observed in solution. (2017)
    Baklouti A, Goulet A, Lichiere J, Canard B, Charrel RN, Ferron F, Coutard B, Papageorgiou N.
    Acta Crystallogr D Struct Biol 73 650-659 PMID:28777080
20. Natural genomic amplification of cholinesterase genes in animals. (2017)
    Chatonnet A, Lenfant N, Marchot P, Selkirk ME.
    J Neurochem 142 Suppl 2 73-81 PMID:28382676
21. The three-finger toxin fold: a multifunctional structural scaffold able to modulate cholinergic functions. (2017)
    Kessler P, Marchot P, Silva M, Servent D.
    J Neurochem 142 Suppl 2 7-18 PMID:28326549
22. Cyclic imine toxins from dinoflagellates: a growing family of potent antagonists of the nicotinic acetylcholine receptors. (2017)
    Molgo J, Marchot P, Araoz R, Benoit E, Iorga BI, Zakarian A, Taylor P, Bourne Y, Servent D.
    J Neurochem 142 Suppl 2 41-51 PMID:28326551
23. NMR assignments of the GacS histidine-kinase periplasmic detection domain from Pseudomonas aeruginosa PAO1. (2017)
    Ali-Ahmad A, Bornet O, Fadel F, Bourne Y, Vincent F, Bordi C, Guerlesquin F, Sebban-Kreuzer C.
    Biomol NMR Assign 11 25-28 PMID:27714507
24. Structural insights into a family 39 glycoside hydrolase from the gut symbiont Bacteroides cellulosilyticus WH2 (2017)
    Ali-Ahmad A, Garron ML, Zamboni V, Lenfant N, Nurizzo D, Henrissat B, Berrin JG, Bourne Y, Vincent F.
    J Struct Biol 197 227-235 PMID:27890857

2016

25. The Hybrid Histidine Kinase LadS Forms a Multicomponent Signal Transduction System with the GacS/GacA Two-Component System in Pseudomonas aeruginosa. (2016)
    Chambonnier G, Roux L, Redelberger D, Fadel F, Filloux A, Sivaneson M, de Bentzmann S, Bordi C.
    PLoS Genet 12 e1006032 PMID:27176226
26. Mechanisms involved in xyloglucan catabolism by the cellulosome-producing bacterium Ruminiclostridium cellulolyticum. (2016)
    Ravachol J, de Philip P, Borne R, Mansuelle P, Mate MJ, Perret S, Fierobe HP.
    Sci Rep 6 22770 PMID:26946939
27. Relationships of human alpha/beta hydrolase fold proteins and other organophosphate-interacting proteins. (2016)
    Lenfant N, Bourne Y, Marchot P, Chatonnet A.
    Chem Biol Interact 259 343-351 PMID:27109753
28. The quaternary structure of a glycoside hydrolase dictates specificity towards beta-glucans. (2016)
    Lafond M, Sulzenbacher G, Freyd T, Henrissat B, Berrin JG, Garron ML.
    J Biol Chem 291 7183-94 PMID:26755730
29. Steric and dynamic parameters influencing in situ cycloadditions to form triazole inhibitors with crystalline acetylcholinesterase. (2016)
    Bourne Y, Sharpless KB, Taylor P, Marchot P.
    J Am Chem Soc 138 1611 - 1621 PMID:26731630

2015

30. Identification of the nucleophile catalytic residue of GH51 alpha-L-arabinofuranosidase from Pleurotus ostreatus. (2015)
    Amore A, Iadonisi A, Vincent F, Faraco V.
    AMB Express 5 79 PMID:26690659
31. RNA 1 and RNA 2 Genomic Segments of Chronic Bee Paralysis Virus Are Infectious and Induce Chronic Bee Paralysis Disease (2015)
    Youssef I, Schurr F, Goulet A, Cougoule N, Ribiere-Chabert M, Darbon H, Thiery R, Dubois E.
    J Immunol Res 2015 423493 PMID:26583154
32. Marine macrocyclic imines, pinnatoxins A and G: structural determinants and functional properties to distinguish neuronal alpha7 from muscle alpha1(2)/beta/gamma/delta nAChRs (2015)
    Bourne Y, Sulzenbacher G, Radic Z, Araoz R, Reynaud M, Benoit E, Zakarian A, Servent D, Molgo J, Taylor P, Marchot P.
    Structure 23 1106-1115 (Preview "From Shellfish Poisoning to Neuroscience" by Shahsavar A and Balle T, Structure 23, 979-980.) PMID:26004441
33. Structural and biochemical characterization of the beta-N-acetylglucosaminidase from Thermotoga maritima: Toward rationalization of mechanistic knowledge in the GH73 family. (2015)
    Lipski A, Herve M, Lombard V, Nurizzo D, Mengin-Lecreulx D, Bourne Y, Vincent F.
    Glycobiology 25 319-330 PMID:25344445
34. Structural basis for carbohydrate binding properties of a plant chitinase-like agglutinin with conserved catalytic machinery. (2015)
    Sulzenbacher G, Roig-Zamboni V, Peumans WJ, Henrissat B, van Damme EJM, Bourne Y.
    J Struct Biol 190 115-121 PMID:25727185
35. A Flexible Extension of the Drosophila Ultrabithorax Homeodomain Defines a Novel Hox/PBC Interaction Mode. (2015)
    Foos N, Maurel-Zaffran C, Mate MJ, Vincentelli R, Hainaut M, Berenger H, Pradel J, Saurin AJ, Ortiz-Lombardia M, Graba Y.
    Structure 23 270-279 PMID:25651060
36. Crystal structure of snake venom acetylcholinesterase in complex with inhibitory antibody fragment Fab410 bound at the peripheral site: evidence for open and closed states of a back door channel. (2015)
    Bourne Y, Renault L, Marchot P.
    J Biol Chem 290 1522-1535 PMID:25411244

2014

37. Special Issue on "Freshwater and marine toxins" (2014)
    Benoit E, Mattei C, Barbier J, Marchot P, Molgo J, Servent D.
    Toxicon 91 1-4 PMID:25456567
38. Functional characterization of a vacuolar invertase from Solanum lycopersicum: post-translational regulation by N-glycosylation and a proteinaceous inhibitor. (2014)
    Tauzin AS, Sulzenbacher G, Lafond M, Desseaux V, Reca IB, Perrier J, Bellincampi D, Fourquet P, Leveque C, Giardina T.
    Biochimie 101 39-49 PMID:24374160
39. Development of an improved variant of GH51 alpha-l-arabinofuranosidase from Pleurotus ostreatus by directed evolution. (2014)
    Giacobbe S, Vincent F, Faraco V.
    N Biotechnol 31 230-6 PMID:24565609
40. Structural and functional characterization of the Clostridium perfringens N-acetylmannosamine-6-phosphate 2-epimerase essential for the sialic acid salvage pathway. (2014)
    Pelissier MC, Sebban-Kreuzer C, Guerlesquin F, Brannigan JA, Bourne Y, Vincent F.
    J Biol Chem 289 35215-35224 PMID:25320079
41. The Neuroligins and Their Ligands: from Structure to Function at the Synapse. (2014)
    Bourne Y, Marchot P.
    J Mol Neurosci 53 387-96 PMID:24497299
42. Tracking the Origin and Divergence of Cholinesterases and Neuroligins: The Evolution of Synaptic Proteins. (2014)
    Lenfant N, Hotelier T, Bourne Y, Marchot P, Chatonnet A.
    J Mol Neurosci 53 362-9 PMID:24390353

2013

43. Molecular Characterization of Monoclonal Antibodies that Inhibit Acetylcholinesterase by Targeting the Peripheral Site and Backdoor Region. (2013)
    Bourne Y, Renault L, Essono S, Mondielli G, Lamourette P, Boquet D, Grassi J, Marchot P.
    PLoS One 8 e77226 PMID:24146971
44. Special issue on "Toxins: From threats to benefits" (2013)
    Martin-Eauclaire MF, Benoit E, Marchot P, Barbier J, Molgo J, Servent D.
    Toxicon 75 1-22 PMID:23927926
45. Dissecting partner recognition by an intrinsically disordered protein using descriptive random mutagenesis. (2013)
    Gruet A, Dosnon M, Vassena A, Lombard V, Gerlier D, Bignon C, Longhi S.
    J Mol Biol 425 3495-509 PMID:23811056
46. ESTHER, the database of the alpha/beta-hydrolase fold superfamily of proteins: tools to explore diversity of functions. (2013)
    Lenfant N, Hotelier T, Velluet E, Bourne Y, Marchot P, Chatonnet A.
    Nucleic Acids Res 41(D1) D423-9 PMID:23193256
47. Proteins with an alpha/beta hydrolase fold: Relationships between subfamilies in an ever-growing superfamily. (2013)
    Lenfant N, Hotelier T, Bourne Y, Marchot P, Chatonnet A.
    Chem Biol Interact 25 266-8 PMID:23010363

2012

48. Structure of human DNase I bound to magnesium and phosphate ions points to a catalytic mechanism common to members of the DNase I-like superfamily. (2012)
    Parsiegla G, Noguere C, Santell L, Lazarus RA, Bourne Y.
    Biochemistry 51 10250-8 PMID:23215638
49. One-step generation of error-prone PCR libraries using Gateway technology. (2012)
    Gruet A, Longhi S, Bignon C.
    Microb Cell Fact 11 14 PMID:22289297
50. Structural insights into antibody sequestering and neutralizing of Na+-channel alpha-type modulator from Old-World scorpion venom. (2012)
    Fabrichny IP, Mondielli G, Conrod S, Martin-Eauclaire MF, Bourne Y, Marchot P.
    J Biol Chem 287 14136-48 PMID:22371498

2011

51. alpha-Galactosidase/sucrose kinase (AgaSK), a novel bifunctional enzyme from the human microbiome coupling galactosidase and kinase activities. (2011)
    Bruel L, Sulzenbacher G, Cervera Tison M, Pujol A, Nicoletti C, Perrier J, Galinier A, Ropartz D, Fons M, Pompeo F, Giardina T.
    J Biol Chem 286 40814-23 PMID:21931163
52. Enzymatic Activity and Protein Interactions in alpha/beta Hydrolase Fold Proteins: Moonlighting versus Promiscuity. (2011)
    Marchot P, Chatonnet A.
    Protein Pept Lett 19 132-43 PMID:21933125
53. Crystal structures of a family 8 polysaccharide lyase reveal open and highly occluded substrate-binding cleft conformations. (2011)
    Elmabrouk ZH, Vincent F, Zhang M, Smith NL, Turkenburg JP, Charnock SJ, Black GW, Taylor EJ.
    Proteins 79 965-74 PMID:21287626

2010

54. Structural insights into the exquisite selectivity of neurexin/neuroligin synaptic interactions. (2010)
    Leone P, Comoletti D, Ferracci G, Conrod S, Garcia SU, Taylor P, Bourne Y, Marchot P.
    EMBO J 29(14) 2461-71 PMID:20543817
55. A new system for expressing recombinant animal toxins in E. coli? (2010)
    Douzi B, Geerlof A, Gilles N, Darbon H, Marchot P, Vincentelli R.
    In: Advances and new technologies in toxinology (Barbier J, Benoit E, Marchot P, Mattei C, Servent D, eds), pp. 149-152, Collection Rencontres en Toxinologie, Publications de la SFET, Chatenay-Malabry, France. PMID:0
56. beta-Glycosyl azides as substrates for a-glycosynthases: preparation of efficient alpha-L-fucosynthases. (2010)
    Cobucci-Pnzano B, Conte F, Bedini E, Corsaro MM, Parrili M, Sulzenbacher G, Lipski A, Dal Piaz F, Lepore L, Rossi M, Moracci M.
    Chem Biol 16 1097-1108 PMID:19875083
57. Crystal Structure of the GalNAc/Gal-Specific Agglutinin from the Phytopathogenic Ascomycete Sclerotinia sclerotiorum Reveals Novel Adaptation of a beta-Trefoil Domain. (2010)
    Sulzenbacher G, Roig-Zamboni V, Peumans WJ, Rouge P, Van Damme EJ, Bourne Y.
    J Mol Biol 400 715-22 PMID:20566411
58. Conformational remodeling of femtomolar inhibitor-acetylcholinesterase complexes in the crystalline state (2010)
    Bourne Y, Radic Z, Taylor P, Marchot P.
    J Am Chem Soc 132 18292-300 PMID:21090615
59. Structure of a polyisoprenoid binding domain from Saccharophagus degradans implicated in plant cell wall breakdown. (2010)
    Vincent F, Molin DD, Weiner RM, Bourne Y, Henrissat B.
    FEBS Lett 584 1577-84 PMID:20227408
60. Structure-function relationships of the alpha/beta-hydrolase fold domain of neuroligin: A comparison with acetylcholinesterase. (2010)
    Leone P, Comoletti D, Taylor P, Bourne Y, Marchot P.
    Chem Biol Interact 187(1-3) 49-55 PMID:20100470
61. Structural determinants in phycotoxins and AChBP conferring high affinity binding and nAChR antagonism (2010)
    Bourne Y, Radic Z, Araoz R, Talley TT, Benoit E, Servent D, Taylor P, Molgo J, Marchot P.
    Proc Natl Acad Sci U S A 107(13) 6076-81 PMID:20224036
62. Structural insights into the catalytic mechanism of bacterial guanosine-diphospho-D-mannose pyrophosphorylase and its regulation by divalent ions. (2010)
    Pelissier MC, Lesley SA, Kuhn P, Bourne Y.
    J Biol Chem 285(35) 27468-76 PMID:20573954
63. Distinct oligomeric forms of the Pseudomonas aeruginosa RetS sensor domain modulate accessibility to the ligand binding site. (2010)
    Vincent F, Round A, Reynaud A, Bordi C, Filloux A, Bourne Y.
    Environ Microbiol 12 1775-86 PMID:20553556
64. A novel alpha-N-acetylgalactosaminidase family with an NAD+-dependent catalytic mechanism suitable for enzymatic removal of blood group A antigens. (2010)
    Sulzenbacher G, Liu QP, Bennett EP, Levery SB, Bourne Y, Ponchel G, Clausen H, Henrissat B.
    Biocatal Biotransfor 28 22-32 PMID:0

2009

65. beta-Glycosyl azides as substrates for alpha-glycosynthases: preparation of efficient alpha-L-fucosynthases. (2009)
    Cobucci-Ponzano B, Conte F, Bedini E, Corsaro MM, Parrilli M, Sulzenbacher G, Lipski A, Dal Piaz F, Lepore L, Rossi M, Moracci M.
    Chem Biol 16 1097-108 PMID:19875083
66. Bacterial glycosidases for the enzymatic removal of blood group antigens (2009)
    Sulzenbacher G, Liu QP, Bennett EP, Spence J, Nudelman E, Levery SB, Bourne Y, Olsson ML, Henrissat B Clausen H.
    8th Carbohydrate Bioengineering Meeting Ischia, Italie, Mai 2009. PMID:0
67. Interaction between the sifa virulence factor and its host target skip is essential for salmonella pathogenesis. (2009)
    Diacovich L, Dumont A, Lafitte D, Soprano E, Guilhon AA, Bignon C, Gorvel JP, Bourne Y, Meresse S.
    J Biol Chem 284 33151-33156 PMID:19801640
68. Structural determinants for interaction of partial agonists with acetylcholine binding protein and neuronal alpha7 nicotinic acetylcholine receptor. (2009)
    Hibbs RE, Sulzenbacher G, Shi J, Talley TT, Conrod S, Kem WR, Taylor P, Marchot P, Bourne Y.
    EMBO J 28 3040-3051 PMID:19696737

2008

69. Glycosyltransferases, glycoside hydrolases: surprise, surprise! (2008)
    Henrissat B, Sulzenbacher G, Bourne Y.
    Curr Opin Struct Biol 18 527-533 PMID:18822375
70. Identification of a GH110 subfamily of alpha1,3-galactosidases: Novel enzymes for removal of the alpha3gal xenotransplantation antigen. (2008)
    Liu QP, Yuan H, Bennett EP, Levery SB, Nudelman E, Spence J, Pietz G, Saunders K, White T, Olsson ML, Henrissat B, Sulzenbacher G, Clausen H..
    J Biol Chem 283 8545-54 PMID:18227066

2007

71. A novel a-N-acetylgalactosaminidase family with a NAD+ dependent catalytic mechanism suitable for enzymatic removal of blood group A antigens (2007)
    Sulzenbacher G, Liu QP, Bennett EP, Spence J, Nudelman E, Levery SB, Bourne Y, Olsson ML, Henrissat B, Clausen H.
    24th European Crystallography Meeting, Marrakesh Marrakesh, Maroc, Aout 2007 PMID:0
72. A novel a-N-acetylgalactosaminidase family with a NAD+ dependent catalytic mechanism suitable for enzymatic removal of blood group A antigens (2007)
    Sulzenbacher G, Liu QP, Bennett EP, Spence J, Nudelman E, Levery SB, Bourne Y, Olsson ML, Henrissat B Clausen H.
    GTBIO GTBIO, Lille, Octobre 2007 PMID:0
73. Structural Analysis of the Synaptic Protein Neuroligin and Its beta-Neurexin Complex: Determinants for Folding and Cell Adhesion. (2007)
    Fabrichny IP, Leone P, Sulzenbacher G, Comoletti D, Miller MT, Taylor P, Bourne Y, Marchot P..
    Neuron 56 979-91 PMID:18093521
74. [Glycosidases for the production of universal blood.] (2007)
    Sulzenbacher G, Bourne Y, Henrissat B.
    Med Sci (Paris) 23 703-5 PMID:17875286
75. Gene overexpression and biochemical characterization of the biotechnologically relevant chlorogenic acid hydrolase from Aspergillus niger (2007)
    Benoit I, Asther M, Bourne Y, Navarro D, Canaan S, Lesage-Meessen L, Herweijer M, Coutinho PM, Asther M, Record E.
    Appl Environ Microbiol 73 5624-32 PMID:17630312
76. Crystal structure of the RNA polymerase domain of the West Nile virus non-structural protein 5. (2007)
    Malet H, Egloff MP, Selisko B, Butcher RE, Wright PJ, Roberts M, Gruez A, Sulzenbacher G, Vonrhein C, Bricogne G, Mackenzie JM, Khromykh AA, Davidson AD, Canard B.
    J Biol Chem 282 10678-10689 PMID:17287213
77. Bacterial glycosidases for the production of universal red blood cells (2007)
    Liu QP, Sulzenbacher G, Yuan H, Bennett EP, Pietz G, Saunders K, Spence J, Nudelman E, Levery SB, White T, Neveu JM, Lane WS, Bourne Y, Olsson ML, Henrissat B, Clausen H.
    Nat Biotechnol 25 454-464 PMID:17401360

2006

78. Conformational states of AChBP revealed by X-ray crystal structures of bound nAChR agonists, antagonists and non-competitive ligands (2006)
    Hansen S, Sulzenbacher G, Huxford T, Marchot P, Bourne Y, Taylor P.
    Acta Pharmacol Sin 27 390 PMID:0
79. Structure and activity of two metal-ion dependent acetyl xylan esterases involved in plant cellwall degradation reveals a close similarity to peptidoglycan deacetylases. (2006)
    Taylor EJ, Gloster TM, Turkenburg JP, Vincent F, Brzozowski AM, Dupont C, Shareck F, Centeno MS, Prates JA, Puchart V, Ferreira LM, Fontes CM, Biely P, Davies GJ.
    J Biol Chem 281 10968-10975 PMID:16431911
80. A year in the life of a medium/large ESRF Allocation Group, a user's point of view. (2006)
    Sulzenbacher G.
    ESRF User Meeting, Feb. 2006 Grenoble PMID:0
81. Crystal structure of LppX, a lipoprotein required for the translocation of phthiocerol dimycocerosates to the surface of Mycobacterium tuberculosis (2006)
    Sulzenbacher G, Canaan S, Bordat Y, Neyrolles O, Stadthagen G, Roig-Zamboni V, Rauzier J, Maurin D, Laval F, Daffe M, Cambillau C, Gicquel B, Bourne Y, Jackson M.
    Colloque de l Association Francaise de Cristallographie Toulouse, Juillet 2006 PMID:0
82. Respective importance of protein folding and glycosylation in the thermal stability of recombinant feruloyl esterase A. (2006)
    Benoit I, Asther M, Sulzenbacher G, Record E, Marmuse L, Parsiegla G, Gimbert I, Asther M, Bignon C.
    FEBS Lett 580 5815-21 PMID:17027758
83. Structural comparison of three crystalline complexes of a peptidic toxin with a synaptic acetylcholine recognition protein. (2006)
    Bourne Y, Hansen SB, Sulzenbacher G, Talley TT, Huxford T, Taylor P, Marchot P.
    J Mol Neurosci 30 103-4 PMID:17192648
84. Structural Characterization of Agonist and Antagonist-Bound Acetylcholine-Binding Protein From Aplysia californica. (2006)
    Hansen SB, Sulzenbacher G, Huxford T, Marchot P, Bourne Y, Taylor P.
    J Mol Neurosci 30 101-2 PMID:17192647
85. Substrate and product trafficking through the active center gorge of acetylcholinesterase analyzed by crystallography and equilibrium binding (2006)
    Bourne Y, Radic Z, Sulzenbacher G, Kim E, Taylor P, Marchot P.
    J Biol Chem 281 29256-29267 PMID:16837465
86. Functional characterization of the glycosyltransferase domain of penicillin-binding protein 1a from Thermotoga maritima (2006)
    Offant J, Michoux F, Dermiaux A, Biton J, Bourne Y.
    Biochim Biophys Acta 1764 1036-42 PMID:16725395
87. LppX is a lipoprotein required for the translocation of phthiocerol dimycocerosates to the surface of Mycobacterium tuberculosis (2006)
    Sulzenbacher G, Canaan S, Bordat Y, Neyrolles O, Stadthagen G, Roig-Zamboni V, Rauzier J, Maurin D, Laval F, Daffe M, Cambillau C, Gicquel B, Bourne Y, Jackson M.
    EMBO J 25 1436-1444 PMID:16541102

2005

88. Expression of the standard scorpion alpha-toxin AaH II and AaH II mutants leading to the identification of some key bioactive elements. (2005)
    Legros C, Ceard B, Vacher H, Marchot P, Bougis PE, Martin-Eauclaire MF.
    Biochim Biophys Acta 1723 91-9 PMID:15725394
89. New friendly tools for users of ESTHER, the database of the alpha/beta-hydrolase fold superfamily of proteins. (2005)
    Renault L, Negre V, Hotelier T, Cousin X, Marchot P, Chatonnet A.
    Chem Biol Interact 157-158 339-43 PMID:16297901
90. A. niger protein "EstA", perhaps a new electrotactin, defines a new class of fungal esterases within the alpha/beta hydrolase fold superfamily. (2005)
    Bourne Y, Hasper AA, Chahinian H, Renault L, Juin M, de Graaff LH, Marchot P.
    Chem Biol Interact 157-158 395-6 PMID:16429533
91. Structural insights into AChE inhibition by monoclonal antibodies. (2005)
    Renault L, Essono S, Juin M, Boquet D, Grassi J, Bourne Y, Marchot P.
    Chem Biol Interact 157-158 397-400 PMID:16429535
92. Structural insights into conformational flexibility at the peripheral site and within the active center gorge of AChE. (2005)
    Bourne Y, Radic Z, Kolb HC, Sharpless KB, Taylor P, Marchot P.
    Chem Biol Interact 157-158 159-165 PMID:16259971
93. Structures of Aplysia AChBP complexes with nicotinic agonists and antagonists reveal distinctive binding interfaces and conformations. (2005)
    Hansen SB, Sulzenbacher G, Huxford T, Marchot P, Taylor P, Bourne Y.
    EMBO J 24 3635-3646 PMID:16193063
94. Crystal structure of a Cbtx-AChBP complex reveals essential interactions between snake alpha-neurotoxins and nicotinic receptors. (2005)
    Bourne Y, Talley TT, Hansen SB, Taylor P, Marchot P.
    EMBO J 24 1512-1522 PMID:15791209
95. Crystal structure of the conserved hypothetical protein Rv1155 from Mycobacterium tuberculosis. (2005)
    Canaan S, Sulzenbacher G, Roig-Zamboni V, Scappuccini-Calvo L, Frassinetti F, Maurin D, Cambillau C, Bourne Y.
    FEBS Lett 579 215-21 PMID:15620716

2004

96. ESTHER, the database of the alpha/beta-hydrolase fold superfamily of proteins. (2004)
    Hotelier T, Renault L, Cousin X, Negre V, Marchot P, Chatonnet A.
    Nucleic Acids Res 32 D145-7 PMID:14681380
97. Freeze-frame inhibitor captures acetylcholinesterase in a unique conformation (2004)
    Bourne Y, Radic Z, Kolb H C, Sharpless K B, Taylor P, Marchot P.
    Proc Natl Acad Sci U S A 101 1449-1454 PMID:14757816
98. Structure of Escherichia coli YhdH, a putative quinone oxidoreductase. (2004)
    Sulzenbacher G, Roig-Zamboni V, Pagot F, Grisel S, Salomoni A, Valencia C, Campanacci V, Vincentelli R, Tegoni M, Eklund H, Cambillau C.
    Acta Crystallogr D Biol Crystallogr 60 1855-62 PMID:15388933
99. Expression and characterization of the protein Rv1399c from Mycobacterium tuberculosis: a novel carboxyl esterase structurally related to the HSL family (2004)
    Canaan S, Maurin D, Chahinian H, Pouilly B, Durousseau C, Frassinetti F, Scappuccini-Calvo L, Cambillau C, Bourne Y.
    Eur J Biochem 271 3953-3961 PMID:15373841
100. Crystal Structure of E.coli Alcohol Dehydrogenase YqhD: Evidence of a Covalently Modified NADP Coenzyme. (2004)
     Sulzenbacher G, Alvarez K, Van Den Heuvel RH, Versluis C, Spinelli S, Campanacci V, Valencia C, Cambillau C, Eklund H, Tegoni M.
     J Mol Biol 342 489-502 PMID:15327949
101. The three-dimensional structure of invertase (beta-fructosidase) from Thermotoga maritima reveals a bimodular arrangement and an evolutionary relationship between retaining and inverting glycosidases (2004)
     Alberto F, Bignon C, Sulzenbacher G, Henrissat B, Czjzek M.
     J Biol Chem 279 18903-18910 PMID:14973124
102. Crystal structure of E. coli YddE protein reveals a striking homolgy with diaminopimelate epimerase (2004)
     Grassick A, Sulzenbacher G, Roig-Zamboni V, Campanacci V, Cambillau C, Bourne Y.
     Proteins 55 764-767 PMID:15103639
103. Aspergillus niger protein EstA defines a new class of fungal esterases within the a/b hydrolase fold superfamily of proteins (2004)
     Bourne Y, Hasper A A, Chahinian H, Juin M, de Graaff L H, Marchot P.
     Structure 12 677-687 PMID:15062090
104. Crystal structure of Thermotoga maritima a-L-fucosidase: Insights into catalytic mechanism and the molecular basis for fucosidosis (2004)
     Sulzenbacher G, Bignon C, Nishimura T, Tarling CA, Withers SG, Henrissat B, Bourne Y.
     J Biol Chem 279 13119-13128 PMID:14715651
105. The crystal structure of the Calystegia sepium agglutinin reveals a novel quaternary arrangement of lectin subunits with a beta -prism fold. (2004)
     Bourne Y, Roig-Zamboni V, Barre A, Peumans WJ, Houles Astoul C, Van Damme EJ, Rouge P.
     J Biol Chem 279 527-533 PMID:14561768

2003

106. Structural insights into ligand interactions at the acetylcholinesterase peripheral anionic site. (2003)
     Bourne Y, Taylor P, Radic Z, Marchot P.
     EMBO J 22 1-12 PMID:12505979
107. The Mtr2-Mex67 NTF2-like domain complex: Structural insights into a dual role of Mtr2 for yeast nuclear export. (2003)
     Senay C, Ferrari P, Rocher C, Rieger KJ, Winter J, Platel D, Bourne Y.
     J Biol Chem 278 48395-48403 PMID:14504280
108. Identification of the catalytic nucleophile of the family 29 alpha -L-fucosidase from Thermotoga maritima through trapping of a covalent glycosyl-enzyme intermediate and mutagenesis. (2003)
     Tarling CA, He S, Sulzenbacher G, Bignon C, Bourne Y, Henrissat B, Withers SG.
     J Biol Chem 278 47394-47399 PMID:12975375
109. Medium-scale structural genomics: strategies for protein expression and crystallization. (2003)
     Vincentelli R, Bignon C, Gruez A, Canaan S, Sulzenbacher G, Tegoni M, Campanacci V, Cambillau C.
     Acc Chem Res 36 165-172 PMID:12641473

2002

110. Use of a purified and functional recombinant calcium-channel beta4 subunit in surface-plasmon resonance studies. (2002)
     Geib S, Sandoz G, Mabrouk K, Matavel A, Marchot P, Hoshi T, Villaz M, Ronjat M, Miquelis R, Leveque C, de Waard M.
     Biochem J 364 285-92 PMID:11988102
111. Mechanism of Acetylcholinesterase Inhibition by Fasciculin: A 5-ns Molecular Dynamics simulation (2002)
     Tai K, Shen T, Henchman RH, Bourne Y, Marchot P, McCammon JA.
     J Am Chem Soc 124 6153-6161 PMID:12022850
112. Structural basis for the unusual carbohydrate-binding specificity of jacalin towards galactose and mannose. (2002)
     Bourne Y, Astoul CH, Zamboni V, Peumans WJ, Menu-Bouaouiche L, Van Damme EJ, Barre A, Rouge P..
     Biochem J 364 173-180 PMID:11988090
113. The size, shape and specificity of the sugar-binding site of the jacalin-related lectins is profoundly affected by the proteolytic cleavage of the subunits. (2002)
     Houles Astoul C, Peumans WJ, Van Damme EJ, Barre A, Bourne Y, Rouge P.
     Biochem J 367 817-824 PMID:12169094
114. A medium-throughput crystallization approach. (2002)
     Sulzenbacher G, Gruez A, Roig-Zamboni V, Spinelli S, Valencia C, Pagot F, Vincentelli R, Bignon C, Salomoni A, Grisel S, Maurin D, Huyghe C, Johansson K, Grassick A, Roussel A, Bourne Y, Perrier S, Miallau L, Cantau P, Blanc E, Genevois M, Grossi A, Zenatti A, Campanacci V, Cambillau C.
     Acta Crystallogr D Biol Crystallogr 58 2109-2115 PMID:12454472

2001

115. Glycoside hydrolases and glycosyltransferases: families and functional modules (2001)
     Bourne Y, Henrissat B.
     Curr Opin Struct Biol 11 593-600 PMID:11785761
116. Immunocytochemical Localization and Crystal Structure of Human Frequenin (Neuronal Calcium Sensor 1) (2001)
     Bourne Y, Dannenberg J, Pollmann V, Marchot P, Pongs O.
     J Biol Chem 276 11949-11955 PMID:11092894
117. Dissection of the bifunctional Escherichia coli GlmU enzyme into autonomously functional domains and evidence that trimerization is absolutely required for glucosamine-1-phosphate acetyltransferase activity and cell growth (2001)
     Pompeo F, Bourne Y, van Heijenoort J, Fassy F, Mengin-Lecreulx D.
     J Biol Chem 276 3833-3839 PMID:11084021
118. The crystal structures of apo and complexed Saccharomyces cerevisiae GNA1 shed light onto the catalytic mechanism of an amino-sugar N-acetyltransferase (2001)
     Peneff C, Mengin-Lecreulx D, Bourne Y.
     J Biol Chem 276 16328-16334 PMID:11278591
119. Mannose-binding plant lectins: Different structural scaffolds for a common sugar-recognition process. (2001)
     Barre A, Bourne Y, Van Damme EJ, Peumans WJ, Rouge P..
     Biochimie 83 645-651 PMID:11522393
120. Crystal structures of two human pyrophosphorylase isoforms in complex with UDPGlc(Gal)NAc: role of the alternatively spiced insert in the enzyme oligomeric assembly and active site architecture (2001)
     Peneff C, Ferrari P, Charrier V, Taburet Y, Monnier C, Zamboni V, Winter J, Harnois M, Fassy F, Bourne Y.
     EMBO J 20 6191-6202 PMID:11707391
121. Crystal structure of Streptococcus pneumoniae N-acetyl-glucosamine-1-phosphate uridyltransferase bound to acetyl-coenzyme A reveals a novel active site architecture (2001)
     Sulzenbacher G, Gal L, Peneff C, Fassy F, Bourne Y.
     J Biol Chem 276 11844-51 PMID:11118459

2000

122. On the kaliotoxin and dendrotoxin binding sites on rat brain synaptosomes. (2000)
     Tricaud N, Marchot P, Martin-Eauclaire MF.
     Toxicon 38 1749-58 PMID:10858514
123. Crystal structure and mutational analysis of the Saccharomyces cerevisiae cell cycle regulatory protein Cks1: implications for domain swapping, anion binding and protein interactions. (2000)
     Bourne Y, Watson MH, Arvai AS, Bernstein SL, Reed SI, Tainer JA.
     Structure Fold Des 8 841-850 PMID:10997903
124. Active and inhibited human catalase structures: ligand and NADPH binding and catalytic mechanism (2000)
     Putnam CD, Arvai AS, Bourne Y, Tainer JA.
     J Mol Biol 296 295-309 PMID:10656833

1999

125. Electron paramagnetic resonance reveals altered topography of the active center gorge of acetylcholinesterase after binding of fasciculin to the peripheral site. (1999)
     Sentjurc M, Pecar S, Stojan J, Marchot P, Radic Z, Grubic Z.
     Biochim Biophys Acta 1430 349-58 PMID:10082962
126. [The fasciculin-acetylcholinesterase interaction]. (1999)
     Marchot P.
     J Soc Biol 193 505-8 PMID:10783708
127. Crystal structure of the bovine beta4galactosyltransferase catalytic domain alone or in the presence of the substrate donor, uridine diphosphogalactose (1999)
     Gastinel L, Cambillau C, Bourne Y.
     EMBO J 18 3546-3557 PMID:10393171
128. Conformational flexibility of the acetylcholinesterase tetramer suggested by X-ray crystallography (1999)
     Bourne Y, Grassi J, Bougis P E, Marchot P.
     J Biol Chem 274 30370-30376 PMID:10521413
129. Crystal Structure of the Bifunctional N-Acetylglucosamine 1-Phosphate Uridyltransferase from E.coli: A Paradigm for the related pyrophosphorylase superfamily (1999)
     Brown K, Pompeo F, Dixon S, Mengin-Lecreux D, Cambillau C, Bourne Y.
     EMBO J 18 4096-107 PMID:10428949
130. Crystal structure of mouse acetylcholinesterase. A peripheral site-occluding loop in a tetrameric assembly. (1999)
     Bourne Y, Taylor P, Bougis PE, Marchot P.
     J Biol Chem 274 2963-2970 PMID:9915834
131. Helianthus tuberosus lectin reveals a widespread scaffold for mannose-binding lectins. (1999)
     Bourne Y, Zamboni V, Barre A, Peumans WJ, Van Damme EJ, Rouge P.
     Structure Fold Des 7(12) 1473-82 PMID:10647178

1998

132. Residues at the subunit interfaces of the nicotinic acetylcholine receptor that contribute to alpha-conotoxin M1 binding. (1998)
     Sugiyama N, Marchot P, Kawanishi C, Osaka H, Molles B, Sine SM, Taylor P.
     Mol Pharmacol 53 787-94 PMID:9547372
133. Toxins selective for subunit interfaces as probes of nicotinic acetylcholine receptor structure. (1998)
     Taylor P, Osaka H, Molles BE, Sugiyama N, Marchot P, Ackermann EJ, Malany S, McArdle JJ, Sine SM, Tsigelny I.
     J Physiol Paris 92 79-83 PMID:9782448
134. Inhibition of mouse acetylcholinesterase by fasciculin: crystal structure of the complex and mutagenesis of fasciculin (1998)
     Marchot P, Bourne Y, Prowse CN, Bougis PE, Taylor P.
     Toxicon 36(11) 1613-22 PMID:9792178
135. Barley a-amylase bound to its endogenous protein inhibitor BASI: crystal structure of the complex at 1.9 A resolution. (1998)
     Vallee F, Kadziola A, Bourne Y, Juy M, Rodenburg KW, Svensson B, Haser R.
     Structure 6(5) 649-59 PMID:9634702

1997

136. Expression and activity of mutants of fasciculin, a peptidic acetylcholinesterase inhibitor from mamba venom. (1997)
     Marchot P, Prowse CN, Kanter J, Camp S, Ackermann EJ, Radic Z, Bougis PE, Taylor P.
     J Biol Chem 272 3502-10 PMID:9013597
137. Pancreatic lipases and their complexes with colipases and inhibitors: crystallization and crystal packing. (1997)
     Cambillau C, Bourne Y, Egloff MP, Martinez C, van Tilbeurgh.
     Methods Enzymol 284 107-19 PMID:9379929

1996

138. Structure of fasciculin 2 from green mamba snake venom: evidence for unusual loop flexibility. (1996)
     le Du MH, Housset D, Marchot P, Bougis PE, Navaza J, Fontecilla-Camps JC.
     Acta Crystallogr D Biol Crystallogr 52 87-92 PMID:15299729
139. Soluble monomeric acetylcholinesterase from mouse: expression, purification, and crystallization in complex with fasciculin. purification/metabolism (1996)
     Marchot P, Ravelli RB, Raves ML, Bourne Y, Vellom DC, Kanter J, Camp S, Sussman JL, Taylor P.
     Protein Sci 5(4) 672-9 PMID:8845756

1995

140. Theoretical analysis of the structure of the peptide fasciculin and its docking to acetylcholinesterase. (1995)
     van den Born HK, Radic Z, Marchot P, Taylor P, Tsigelny I.
     Protein Sci 4 703-15 PMID:7613468
141. Structural bases for the specificity of cholinesterase catalysis and inhibition. (1995)
     Taylor P, Radic Z, Hosea NA, Camp S, Marchot P, Berman HA.
     Toxicol Lett 82-83 453-8 PMID:8597093
142. Acetylcholinesterase inhibition by fasciculin: crystal structure of the complex. (1995)
     Bourne Y, Taylor P, Marchot P.
     Cell 83 503-12 PMID:8521480

1994

143. Horse pancreatic lipase. The crystal structure refined at 2.3 A resolution. (1994)
     Bourne Y, Martinez C, Kerfelec B, Lombardo D, Chapus C, Cambillau C.
     J Mol Biol 238 709-32 PMID:8182745

1992

144. A fibrinogen-clotting serine proteinase from Cerastes cerastes (horned viper) venom with arginine-esterase and amidase activities. Purification, characterization and kinetic parameter determination. (1992)
     Laraba-Djebari F, Martin-Eauclaire MF, Marchot P.
     Toxicon 30 1399-410 PMID:1485336
145. 1.9-A resolution structure of fasciculin 1, an anti-acetylcholinesterase toxin from green mamba snake venom. (1992)
     le Du MH, Marchot P, Bougis PE, Fontecilla-Camps JC.
     J Biol Chem 267 22122-30 PMID:1429564

1990

146. [Neurotoxicity in mice due to cysteine-rich parts of visna virus and HIV-1 Tat proteins]. (1990)
     Gourdou I, Mabrouk K, Harkiss G, Marchot P, Watt N, Hery F, Vigne R.
     C R Acad Sci III 311 149-55 PMID:2169973
147. Homologues of a K+ channel blocker alpha-dendrotoxin: characterization of synaptosomal binding sites and their coupling to elevation of cytosolic free calcium concentration. (1990)
     Muniz MH, Tibbs GR, Marchot P, Bougis PE, Nicholls DG, Dolly JO.
     Neurochem Int 16 105-12 PMID:0
148. Three-dimensional structures of complexes of Lathyrus ochrus isolectin I with glucose and mannose: fine specificity of the monosaccharide-binding site. (1990)
     Bourne Y, Roussel A, Frey M, Rouge P, Fontecilla-Camps JC, Cambillau C.
     Proteins 8 365-76 PMID:2091026
149. Three-dimensional structures of complexes of Lathyrus ochrus isolectin I with glucose and mannose: fine specificity of the monosaccharide- binding site. (1990)
     Bourne Y, Roussel A, Frey M, Rouge P, Fontecilla-Camps JC, Cambillau C.
     Proteins 8 365-76 PMID:2091026
150. X-ray structure of a (a-Man(1-3)beta-Man(1-4)GlcNAc)-lectin complex at 2.1-A resolution. The role of water in sugar-lectin interaction. (1990)
     Bourne Y, Rouge P, Cambillau C.
     J Biol Chem 265 18161-5 PMID:2211692
151. X-ray crystal structure determination and refinement at 1.9 A resolution of isolectin I from the seeds of Lathyrus ochrus. (1990)
     Bourne Y, Abergel C, Cambillau C, Frey M, Rouge P, Fontecilla-Camps JC.
     J Mol Biol 214(2) 571-84 PMID:2380988
152. Co-crystallization and preliminary X-ray diffraction studies of Lathyrus ochrus isolectin I with di- and trisaccharides, and a biantennary octosaccharide. (1990)
     Bourne Y, Anguille C, Fontecilla-Camps JC, Rouge P, Cambillau C.
     J Mol Biol 213(2) 211-3 PMID:2342103

1989

153. Crystallization and preliminary X-ray study of horse pancreatic lipase (1989)
     Lombardo D, Chapus C, Bourne Y, Cambillau C.
     J Mol Biol 205 259-261 PMID:2926806
154. Crystals of fasciculin 2 from green mamba snake venom. Preparation and preliminary x-ray analysis. (1989)
     le Du MH, Marchot P, Bougis PE, Fontecilla-Camps JC.
     J Biol Chem 264 21401-2 PMID:2592383

1988

155. Crystallization and preliminary X-ray studies of two isolectins from the seeds of Lathyrus ochrus (1988)
     Bourne Y, Rouge P, Cambillau C..
     J Mol Biol 202 685-7 PMID:3172234
156. Selective loss of binding sites for the iodinated alpha-neurotoxin I from Naja mossambica mossambica venom upon enzymatic deglycosylation of Torpedo electric organ membranes. (1988)
     Zeghloul S, Marchot P, Bougis PE, Ronin C.
     Eur J Biochem 174 543-50 PMID:3134197
157. Selective distinction at equilibrium between the two alpha-neurotoxin binding sites of Torpedo acetylcholine receptor by microtitration. (1988)
     Marchot P, Frachon P, Bougis PE.
     Eur J Biochem 174 537-42 PMID:3391171
158. Localization of the toxic site of Naja mossambica cardiotoxins: small synthetic peptides express an in vivo lethality. (1988)
     Marchot P, Bougis PE, Ceard B, Van Rietschoten J, Rochat H.
     Biochem Biophys Res Commun 153 642-7 PMID:3382394

1987

159. In vivo synergy of cardiotoxin and phospholipase A2 from the elapid snake Naja mossambica mossambica. (1987)
     Bougis PE, Marchot P, Rochat H.
     Toxicon 25 427-31 PMID:3617080
160. Use of high performance liquid chromatography to demonstrate quantitative variation in components of venom from the scorpion Androctonus australis Hector. (1987)
     Martin MF, Rochat H, Marchot P, Bougis PE.
     Toxicon 25 569-73 PMID:3617091
161. Monitoring the purification by high-performance liquid chromatography of cardiotoxins from Naja mossambica mossambica using phase-sensitive two-dimensional nuclear magnetic resonance. (1987)
     Otting G, Marchot P, Bougis PE, Rochat H, Wuthrich K.
     Eur J Biochem 168 603-7 PMID:3665936

1986

162. Characterization of elapidae snake venom components using optimized reverse-phase high-performance liquid chromatographic conditions and screening assays for alpha-neurotoxin and phospholipase A2 activities. (1986)
     Bougis PE, Marchot P, Rochat H.
     Biochemistry 25 7235-43 PMID:3801413