{"id":5673,"date":"2023-02-20T11:43:21","date_gmt":"2023-02-20T10:43:21","guid":{"rendered":"https:\/\/www.afmb.univ-mrs.fr\/?post_type=event&#038;p=5673"},"modified":"2023-03-10T12:49:01","modified_gmt":"2023-03-10T11:49:01","slug":"s-longhi-teams-guest-stefano-ricagno-university-of-milan","status":"publish","type":"event","link":"https:\/\/www.afmb.univ-mrs.fr\/en\/event\/s-longhi-teams-guest-stefano-ricagno-university-of-milan\/","title":{"rendered":"S. Longhi&#8217;s team guest: Stefano Ricagno, University of Milan &#8211; &#8220;Ex-vivo structural biology: new insights on systemic amyloidosis&#8221;."},"content":{"rendered":"\n<h2 class=\"wp-block-heading\">Abstract<\/h2>\n\n\n\n<p>Systemic amyloidoses are a group of life-threatening diseases whereby large deposits of amyloid fibrils&nbsp;are accumulated in one or several internal organs causing tissue alterations and organ failure.&nbsp;Using single particle Cryo-electron microscopy (Cryo-EM) we characterize&nbsp;amyloid deposits directly extracted from the tissue of affected individuals, allowing the direct analysis of the pathologic misfolded assemblies.&nbsp;Cryo-EM structure of amyloids extracted from cardiac and renal tissues of patients affected by Light Chain amyloidosis, from kidneys of patients from AA amyloidosis will be presented and discussed.<\/p>\n","protected":false},"template":"","events_category":[16],"class_list":["post-5673","event","type-event","status-publish","hentry","events_category-webinar","entry"],"_links":{"self":[{"href":"https:\/\/www.afmb.univ-mrs.fr\/en\/wp-json\/wp\/v2\/event\/5673","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.afmb.univ-mrs.fr\/en\/wp-json\/wp\/v2\/event"}],"about":[{"href":"https:\/\/www.afmb.univ-mrs.fr\/en\/wp-json\/wp\/v2\/types\/event"}],"wp:attachment":[{"href":"https:\/\/www.afmb.univ-mrs.fr\/en\/wp-json\/wp\/v2\/media?parent=5673"}],"wp:term":[{"taxonomy":"events_category","embeddable":true,"href":"https:\/\/www.afmb.univ-mrs.fr\/en\/wp-json\/wp\/v2\/events_category?post=5673"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}