{"id":7542,"date":"2023-03-09T16:36:59","date_gmt":"2023-03-09T15:36:59","guid":{"rendered":"https:\/\/www.afmb.univ-mrs.fr\/?post_type=event&#038;p=7542"},"modified":"2023-03-14T12:48:39","modified_gmt":"2023-03-14T11:48:39","slug":"j-reguera-team-guest-michael-mons-embl-grenoble-exploring-structures-in-chikungunya-viral-replication-and-in-neural-axon-fate-by-cryo-em","status":"publish","type":"event","link":"https:\/\/www.afmb.univ-mrs.fr\/en\/event\/j-reguera-team-guest-michael-mons-embl-grenoble-exploring-structures-in-chikungunya-viral-replication-and-in-neural-axon-fate-by-cryo-em\/","title":{"rendered":"J. Reguera&#8217;s team guest: Michael Hons, EMBL Grenoble &#8211; &#8220;Exploring structures in Chikungunya viral replication and in neural axon fate by cryo-EM&#8221;"},"content":{"rendered":"\n<h2 class=\"wp-block-heading\">Abstract<\/h2>\n\n\n\n<p>Within EMBL Grenoble, I explored by cryo-EM structures related to Chikungunya Viral Replication (1) and Axonal Wallerian Degeneration (2) and we developed a cryo-EM automatization pipeline called \u2018Easygrid\u2019 (3). I will present how we use single-particle cryo-EM to structurally decipher the role of nsP1\/3 in Chikungunya Viral Replication (1) and the process of Wallerian Degeneration in Axons (2). I will introduce Easygrid (3), an automated cryo-EM grid preparation and evaluation pipeline for single-particle and in situ cryo-EM. From human pathogenic Chikungunya Virus, I will build a bridge towards another +ssRNA virus: Plant pathogenic Potyvirus Y. I will present how I aim to study Potyvirus Y Replication using single-particle and in situ cryo-EM approaches.<\/p>\n","protected":false},"template":"","events_category":[16],"class_list":["post-7542","event","type-event","status-publish","hentry","events_category-webinar","entry"],"_links":{"self":[{"href":"https:\/\/www.afmb.univ-mrs.fr\/en\/wp-json\/wp\/v2\/event\/7542","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.afmb.univ-mrs.fr\/en\/wp-json\/wp\/v2\/event"}],"about":[{"href":"https:\/\/www.afmb.univ-mrs.fr\/en\/wp-json\/wp\/v2\/types\/event"}],"wp:attachment":[{"href":"https:\/\/www.afmb.univ-mrs.fr\/en\/wp-json\/wp\/v2\/media?parent=7542"}],"wp:term":[{"taxonomy":"events_category","embeddable":true,"href":"https:\/\/www.afmb.univ-mrs.fr\/en\/wp-json\/wp\/v2\/events_category?post=7542"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}