Publications

2022

2022
A dual mechanism of action of AT-527 against SARS-CoV-2 polymerase

Ashleigh Shannon, Véronique Fattorini, Bhawna Sama, Barbara Selisko, Mikael Feracci, Camille Falcou, Pierre Gauffre, Priscila El Kazzi, Adrien Delpal, Etienne Decroly, Karine Alvarez, Cécilia Eydoux, Jean-Claude Guillemot, Adel Moussa, Steven S Good, Paolo La Colla, Kai Lin, Jean-Pierre Sommadossi, yingxiao Zhu, Xiaodong yan, Hui Shi, Francois Ferron, Bruno Canard

Nature Communications 13 (2022)10.1038/s41467-022-28113-1

2021

2021
Fragment-based drug design targeting syntenin PDZ2 domain involved in exosomal release and tumour spread

Manon Garcia, Laurent Hoffer, Raphaël Leblanc, Fatiha Benmansour, Mikael Feracci, Carine Derviaux, Antonio Luis Egea-Jimenez, Philippe Roche, Pascale Zimmermann, Xavier Morelli, Karine Barral

European Journal of Medicinal Chemistry 223:113601 (2021)10.1016/j.ejmech.2021.113601

2020

2020
Pharmacological inhibition of syntenin PDZ2 domain impairs breast cancer cell activities and exosome loading with syndecan and EpCAM cargo

R. Leblanc, R. Kashyap, K. Barral, A.L. Egea‐jimenez, D. Kovalskyy, M. Feracci, M. Garcia, C. Derviaux, S. Betzi, R. Ghossoub, M. Platonov, P. Roche, X. Morelli, L. Hoffer, Pascale Zimmermann

Journal of Extracellular Vesicles 10 (2020)10.1002/jev2.12039

2020
In silico molecular target prediction unveils mebendazole as a potent MAPK14 inhibitor

Jeremy Ariey‐bonnet, Kendall Carrasco, Marion Le Grand, Laurent Hoffer, Stéphane Betzi, Mikael Feracci, Philipp A Tsvetkov, François Devred, yves Collette, Xavier Morelli, Pedro Ballester, Eddy Pasquier

Molecular Oncology 14:3083-3099 (2020)10.1002/1878-0261.12810

2017

2017
Binding site density enables paralog-specific activity of SLM2 and Sam68 proteins in Neurexin2 AS4 splicing control

Marina Danilenko, Caroline Dalgliesh, Vittoria Pagliarini, Chiara Naro, Ingrid Ehrmann, Mikael Feracci, Mahsa Kheirollahi-Chadegani, Alison Tyson-Capper, Gavin Clowry, Philippe Fort, Cyril Dominguez, Claudio Sette, David Elliott

Nucleic Acids Research 45:gkw1277 (2017)10.1093/nar/gkw1277

2014

2014
Identification of a Src kinase SH3 binding site in the C-terminal domain of the human ErbB2 receptor tyrosine kinase.

Olivier Bornet, Matthieu Nouailler, Michaël Feracci, Corinne Sebban-Kreuzer, Deborah Byrne, Hubert Halimi, Xavier Morelli, Ali Badache, Francoise Guerlesquin

FEBS Letters 588:2031-6 (2014)10.1016/j.febslet.2014.04.029

2012

2012
Structural Basis for Galectin-1-dependent Pre-B Cell Receptor (Pre-BCR) Activation

Latifa Elantak, Marion Espeli, Annie Boned, Olivier Bornet, Jeremy Bonzi, Laurent Gauthier, Mikael Feracci, Philippe Roche, Francoise Guerlesquin, Claudine Schiff

Journal of Biological Chemistry 287:44703-44713 (2012)10.1074/jbc.m112.395152

2012
Structural basis for galectin-1-dependent pre-B cell receptor (pre-BCR) activation.

Latifa El Antak, Marion Espeli, Annie Boned, Olivier Bornet, Jeremy Bonzi, Laurent Gauthier, Mikael Feracci, Philippe Roche, Françoise Guerlesquin, Claudine Schiff

Journal of Biological Chemistry 287:44703-13 (2012)10.1074/jbc.M112.395152

2011

2011
MEMO associated with an ErbB2 receptor phosphopeptide reveals a new phosphotyrosine motif.

Mikael Feracci, Cyril Pimentel, Olivier Bornet, Philippe Roche, Danièle Salaün, Ali Badache, Françoise Guerlesquin

FEBS Letters 585:2688-92 (2011)10.1016/j.febslet.2011.07.048

2009

2009
NMR and MD investigations of human galectin-1/oligosaccharide complexes.

Christophe Meynier, Mikael Feracci, Marion Espeli, Florence Chaspoul, Philippe Gallice, Claudine Schiff, Françoise Guerlesquin, Roche Philippe

Biophysical Journal 97:3168-77 (2009)10.1016/j.bpj.2009.09.026