The Architecture et Fonction des Macromolécules Biologiques (AFMB) laboratory is a center of structural biology localized on the Luminy campus in the South of Marseilles, France. It is overseen by the CNRS and AMU (UMR 7257) and in partnership with INRAE (USC AFMB 1408).

The aim of our researches is to depict the architecture of proteins or macromolecular assemblies at the molecular level to understand the biological mechanisms which they govern. The description of interactions between macromolecules or a macromolecule and a ligand is also crucial to manipulate these complex molecules. Finally, to understand the molecular diversity of members of some protein families, we also analyze the big data issued from large-scale genome sequencing centers.