The CAZy bioinformatics
This facility is based on the bioinformatics tools and curation efforts associated to the CAZy database, updated by the Glycogenomics team since its launch in September 1998.
This facility analyzes genomes and metagenomic datasets in order to identify the encoded enzymes for the assembly and breakdown of complex carbohydrates. The enzymes currently covered in our analyses include the glycoside hydrolases, glycosyltransferases, polysaccharide lyases, carbohydrate esterases, and auxiliary redox proteins such as lytic polysaccharide mono-oxygenases). We offer several levels of analysis ranging from automatic analysis to manual curation.
Access to
Academic and private companies
Cost
Private companies: to be discussed (based on data volume, computer time required and human resources implicated). Academics: collaboration basis.
Contact
- Contact AFMB : Vincent Lombard
Specific Equipement
- 1 HPC with 616 cores
- 1 HPC with 64 cores
- 4 SMP computers with 64 cores
Team contacts
Examples of publications that made use of our platform
- Seedorf et al. (2014) Bacteria from diverse habitats colonize and compete in the mouse gut. Cell 159, 1-14
- Ridaura et al. (2013) Gut microbiota from twins discordant for obesity modulate metabolism in mice. Science 341:1241214.
- Floudas et al. (2012) The Paleozoic origin of white rot wood decay reconstructed using 31 fungal genomes. Science 336, 1715-1719
- Ohm et al. (2012) Diverse lifestyles and strategies of plant pathogenesis encoded in the genomes of eighteen Dothideomycetes fungi. PLoS Pathogens 8(12) : e1003037
- Muegge et al. (2011) Diet drives convergence in gut microbiome functions across mammalian phylogeny and within humans. Science 332, 970-974
