2022

2022
SARS-CoV-2 detection using a nanobody-functionalized voltammetric device

Quentin Pagneux, Alain Roussel, Hiba Saada, Christian Cambillau, Béatrice Amigues, Vincent Delauzun, Ilka Engelmann, Enagnon Kazali Alidjinou, Judith Ogiez, Anne Sophie Rolland, Emmanuel Faure, Julien Poissy, Alain Duhamel, Rabah Boukherroub, David Devos, Sabine Szunerits

Communications Medicine 2:56 (2022)10.1038/s43856-022-00113-8

2022
Gut microbiome of the largest living rodent harbors unprecedented enzymatic systems to degrade plant polysaccharides

Lucelia Cabral, Gabriela Persinoti, Douglas Paixão, Marcele Martins, Mariana Morais, Mariana Chinaglia, Mariane Domingues, Mauricio Sforca, Renan Pirolla, Wesley Generoso, Clelton Santos, Lucas Maciel, Nicolas Terrapon, Vincent Lombard, Bernard Henrissat, Mario Murakami

Nature Communications 13:629 (2022)10.1038/s41467-022-28310-y

2022
Exploring the impact of Verticillium wilt disease on the mechanical properties of elementary flax (Linum usitatissimum L.) fibres

Lucile Nuez, Sylvie Durand, Alessia Melelli, Jean-Guy Berrin, Mireille Haon, Elodie Drula, Johnny Beaugrand, Pierre D’arras, Alain Bourmaud, Christophe Baley

Industrial Crops and Products 182:114900 (2022)10.1016/j.indcrop.2022.114900

2022
Arenaviridae NP-exonuclease inhibition by bisphosphonate

Thi Hong van Nguyen, Elsie yekwa, Barbara Selisko, Bruno Canard, Karine Alvarez, Francois Ferron

IUCrJ 9 (2022)10.1107/S2052252522005061

2022
Insights into the atypical autokinase activity of the Pseudomonas aeruginosa GacS histidine kinase and its interaction with RetS

Firas Fadel, Violla Bassim, Vanessa Francis, Steven Porter, Thomas Botzanowski, Pierre Legrand, Maria Maté Perez, Yves Bourne, Sarah Cianférani, Florence Vincent

Structure (2022)10.1016/j.str.2022.06.002

2022
Patient-derived antibodies reveal the subcellular distribution and heterogeneous interactome of LGI1

Jorge Ramirez-Franco, Kévin Debreux, Johanna Extremet, Yves Maulet, Maya Belghazi, Claude Villard, Marion Sangiardi, Fahamoe Youssouf, Lara El Far, Christian Lévêque, Claire Debarnot, Pascale Marchot, Sofija Paneva, Dominique Debanne, Michael Russier, Michael Seagar, Sarosh Irani, Oussama El Far

Brain - A Journal of Neurology (2022)10.1093/brain/awac218

2022
The Land–Sea Connection: Insights Into the Plant Lineage from a Green Algal Perspective

Charles Bachy, Fabian Wittmers, Jan Muschiol, Maria Hamilton, Bernard Henrissat, Alexandra Worden

Annual Review of Plant Biology 73 (2022)10.1146/annurev-arplant-071921-100530

2022
Molecular basis for substrate recognition and septum cleavage by AtlA, the major N-acetylglucosaminidase of Enterococcus faecalis

Véronique Roig-Zamboni, Sarah Barelier, Robert Dixon, Nicola Galley, Amani Ghanem, Quoc Phong Nguyen, Héloize Cahuzac, Bartłomiej Salamaga, Peter Davis, Yves Bourne, Stéphane Mesnage, Florence Vincent

Journal of Biological Chemistry 298:101915 (2022)10.1016/j.jbc.2022.101915

2022
Functional exploration of the glycoside hydrolase family GH113

Marie Couturier, Mélanie Touvrey-Loiodice, Nicolas Terrapon, Elodie Drula, Laurine Buon, Christine Chirat, Bernard Henrissat, William Helbert

PLoS ONE 17:e0267509 (2022)10.1371/journal.pone.0267509

2022
Distribution of Charged Residues Affects the Average Size and Shape of Intrinsically Disordered Proteins

Greta Bianchi, Marco Mangiagalli, Alberto Barbiroli, Sonia Longhi, Rita Grandori, Carlo Santambrogio, Stefania Brocca

Biomolecules 12:561 (2022)10.3390/biom12040561

2022
Mechanistic insights into consumption of the food additive xanthan gum by the human gut microbiota

Matthew Ostrowski, Sabina Leanti La Rosa, Benoit Kunath, Andrew Robertson, Gabriel Pereira, Live Hagen, Neha Varghese, Ling Qiu, Tianming yao, Gabrielle Flint, James Li, Sean Mcdonald, Duna Buttner, Nicholas Pudlo, Matthew Schnizlein, Vincent young, Harry Brumer, Thomas Schmidt, Nicolas Terrapon, Vincent Lombard, Bernard Henrissat, Bruce Hamaker, Emiley Eloe-Fadrosh, Ashootosh Tripathi, Phillip Pope, Eric Martens

Nature Microbiology 7:556-569 (2022)10.1038/s41564-022-01093-0

2022
Molecular basis for substrate recognition and septum cleavage by AtlA, the major N-acetylglucosaminidase of Enterococcus faecalis

Véronique Roig-Zamboni, Sarah Barelier, Robert Dixon, Nicola Galley, Amani Ghanem, Quoc Phong Nguyen, Héloize Cahuzac, Bartłomiej Salamaga, Peter Davis, yves Bourne, Stéphane Mesnage, Florence Vincent

Journal of Biological Chemistry 101915 (2022)10.1016/j.jbc.2022.101915

2022
Assembly and synthesis of the extracellular matrix in brown algae

Lisa Mazéas, Rina yonamine, Tristan Barbeyron, Bernard Henrissat, Elodie Drula, Nicolas Terrapon, Chikako Nagasato, Cécile Hervé

Seminars in Cell and Developmental Biology (2022)10.1016/j.semcdb.2022.03.005

2022
Evolutionary transition to the ectomycorrhizal habit in the genomes of a hyperdiverse lineage of mushroom‐forming fungi

Brian Looney, Shingo Miyauchi, Emmanuelle Morin, Elodie Drula, Pierre Emmanuel Courty, Annegret Kohler, Alan Kuo, Kurt Labutti, Jasmyn Pangilinan, Anna Lipzen, Robert Riley, William Andreopoulos, Guifen He, Jenifer Johnson, Matt Nolan, Andrew Tritt, Kerrie Barry, Igor Grigoriev, László Nagy, David Hibbett, Bernard Henrissat, P. Brandon Matheny, Jesse Labbé, Francis Martin

New Phytologist 233:2294-2309 (2022)10.1111/nph.17892

2022
The ectomycorrhizal basidiomycete Laccaria bicolor releases a GH28 polygalacturonase that plays a key role in symbiosis establishment

Feng Zhang, Aurore Labourel, Mireille Haon, Minna Kemppainen, Emilie da Silva Machado, Nicolas Brouilly, Claire Veneault-Fourrey, Annegret Kohler, Marie‐noëlle Rosso, Alejandro Pardo, Bernard Henrissat, Jean‐guy Berrin, Francis Martin

New Phytologist 233:2534-2547 (2022)10.1111/nph.17940

2022
Phylogenomics and Comparative Genomics Highlight Specific Genetic Features in Ganoderma Species

yi-Fei Sun, Annie Lebreton, Jia-Hui Xing, yu-Xuan Fang, Jing Si, Emmanuelle Morin, Shingo Miyauchi, Elodie Drula, Steven Ahrendt, Kelly Cobaugh, Anna Lipzen, Maxim Koriabine, Robert Riley, Annegret Kohler, Kerrie Barry, Bernard Henrissat, Igor Grigoriev, Francis Martin, Bao-Kai Cui

Journal of Fungi 8:311 (2022)10.3390/jof8030311

2022
Phenotypic and Genomic Diversification in Complex Carbohydrate-Degrading Human Gut Bacteria

Nicholas Pudlo, Karthik Urs, Ryan Crawford, Ali Pirani, Todd Atherly, Roberto Jimenez, Nicolas Terrapon, Bernard Henrissat, Daniel Peterson, Cherie Ziemer, Evan Snitkin, Eric Martens

mSystems 7:e0094721 (2022)10.1128/msystems.00947-21

2022
A dual mechanism of action of AT-527 against SARS-CoV-2 polymerase

Ashleigh Shannon, Véronique Fattorini, Bhawna Sama, Barbara Selisko, Mikael Feracci, Camille Falcou, Pierre Gauffre, Priscila El Kazzi, Adrien Delpal, Etienne Decroly, Karine Alvarez, Cécilia Eydoux, Jean-Claude Guillemot, Adel Moussa, Steven S Good, Paolo La Colla, Kai Lin, Jean-Pierre Sommadossi, yingxiao Zhu, Xiaodong yan, Hui Shi, Francois Ferron, Bruno Canard

Nature Communications 13 (2022)10.1038/s41467-022-28113-1

2022
Structural and functional analyses of the Porphyromonas gingivalis type IX secretion system PorN protein

Olivier Fuchsbauer, Ignacio Lunar Silva, Eric Cascales, Alain Roussel, Philippe Leone

Journal of Biological Chemistry 298 (2022)10.1016/j.jbc.2022.101618

2022
Experimental Evidence of Intrinsic Disorder and Amyloid Formation by the Henipavirus W Proteins

Giulia Pesce, Frank Gondelaud, Denis Ptchelkine, Juliet F Nilsson, Christophe Bignon, Jérémy Cartalas, Patrick Fourquet, Sonia Longhi

International Journal of Molecular Sciences 23:923 (2022)10.3390/ijms23020923

2022
Fluoxetine targets an allosteric site in the enterovirus 2C AAA+ ATPase and stabilizes a ring-shaped hexameric complex

Daniel L Hurdiss, Priscila El Kazzi, Lisa Bauer, Nicolas Papageorgiou, Francois Ferron, Tim Donselaar, Arno L.W. van Vliet, Tatiana M Shamorkina, Joost Snijder, Bruno Canard, Etienne Decroly, Andrea Brancale, Tzviya Zeev-Ben-Mordehai, Friedrich Förster, Frank J.M. van Kuppeveld, Bruno Coutard

Science Advances 8 (2022)10.1126/sciadv.abj7615

2022
The carbohydrate-active enzyme database: functions and literature

Elodie Drula, Marie-Line Garron, Suzan Dogan, Vincent Lombard, Bernard Henrissat, Nicolas Terrapon

Nucleic Acids Research 50:D571-D577 (2022)10.1093/nar/gkab1045

2022
DisProt in 2022: improved quality and accessibility of protein intrinsic disorder annotation

Federica Quaglia, Bálint Mészáros, Edoardo Salladini, András Hatos, Rita Pancsa, Lucía B Chemes, Mátyás Pajkos, Tamas Lazar, Samuel Peña-Díaz, Jaime Santos, Veronika Ács, Nazanin Farahi, Erzsébet Fichó, Maria Cristina Aspromonte, Claudio Bassot, Anastasia Chasapi, Norman E Davey, Radoslav Davidović, Laszlo Dobson, Arne Elofsson, Gábor Erdős, Pascale Gaudet, Michelle Giglio, Juliana Glavina, Javier Iserte, Valentín Iglesias, Zsófia Kálmán, Matteo Lambrughi, Emanuela Leonardi, Sonia Longhi, Sandra Macedo-Ribeiro, Emiliano Maiani, Julia Marchetti, Cristina Marino-Buslje, Attila Mészáros, Alexander Miguel Monzon, Giovanni Minervini, Suvarna Nadendla, Juliet F Nilsson, Marian Novotný, Christos A Ouzounis, Nicolás Palopoli, Elena Papaleo, Pedro José Barbosa Pereira, Gabriele Pozzati, Vasilis J Promponas, Jordi Pujols, Alma Carolina Sanchez Rocha, Martin Salas, Luciana Rodriguez Sawicki, Eva Schad, Aditi Shenoy, Tamás Szaniszló, Konstantinos D Tsirigos, Nevena Veljkovic, Gustavo Parisi, Salvador Ventura, Zsuzsanna Dosztányi, Peter Tompa, Silvio C E Tosatto, Damiano Piovesan

Nucleic Acids Research 50:D480-D487 (2022)10.1093/nar/gkab1082

2022
The role of the surface ligand on the performance of electrochemical SARS-CoV-2 antigen biosensors

Sabine Szunerits, Quentin Pagneux, Abir Swaidan, Vladyslav Mishyn, Alain Roussel, Christian Cambillau, David Devos, Ilka Engelmann, Enagnon Kazali Alidjinou, Henri Happy, Rabah Boukherroub

Analytical and Bioanalytical Chemistry 414:pp 103-113 (2022)10.1007/s00216-020-03137-y

2022
Synthesis, Structure–Activity Relationships, and Antiviral Profiling of 1-Heteroaryl-2-Alkoxyphenyl Analogs As Inhibitors of SARS-CoV-2 Replication

Dorothée Bardiot, Laura Vangeel, Mohamed Koukni, Philippe Arzel, Marleen Zwaagstra, Heyrhyoung Lyoo, Patrick Wanningen, Shamshad Ahmad, Linlin Zhang, Xinyuanyuan Sun, Adrien Delpal, Cecilia Eydoux, Jean-Claude Guillemot, Eveline Lescrinier, Hugo Klaassen, Pieter Leyssen, Dirk Jochmans, Karolien Castermans, Rolf Hilgenfeld, Colin Robinson, Etienne Decroly, Bruno Canard, Eric J Snijder, Martijn J Van Hemert, Frank Van van Kuppeveld, Patrick Chaltin, Johan Neyts, Steven De de Jonghe, Arnaud Marchand

Molecules 27:1052 (2022)10.3390/molecules27031052

2022