Publications

2022

2022
Fluoxetine targets an allosteric site in the enterovirus 2C AAA+ ATPase and stabilizes a ring-shaped hexameric complex

Daniel L Hurdiss, Priscila El Kazzi, Lisa Bauer, Nicolas Papageorgiou, Francois Ferron, Tim Donselaar, Arno L.W. van Vliet, Tatiana M Shamorkina, Joost Snijder, Bruno Canard, Etienne Decroly, Andrea Brancale, Tzviya Zeev-Ben-Mordehai, Friedrich Förster, Frank J.M. van Kuppeveld, Bruno Coutard

Science Advances 8 (2022)10.1126/sciadv.abj7615

2021

2021
Observation of arenavirus nucleoprotein heptamer assembly

Nicolas Papageorgiou, Afroditi Vaitsopoulou, Awa Diop, Thi Hong van Nguyen, Bruno Canard, Karine Alvarez, Francois Ferron

FEBS Open Bio (2021)10.1002/2211-5463.13106

2020

2020
Brothers in Arms: Structure, Assembly and Function of Arenaviridae Nucleoprotein

Nicolas Papageorgiou, Maria Spiliopoulou, Thi-Hong van Nguyen, Afroditi Vaitsopoulou, Elsie yekwa Laban, Karine Alvarez, Irene Margiolaki, Bruno Canard, Francois Ferron

Viruses 12:772 (2020)10.3390/v12070772

2019

2019
Deciphering the Nucleotide and RNA Binding Selectivity of the Mayaro Virus Macro Domain

Aikaterini Tsika, Efstathios Melekis, Sofia-Antigoni Tsatsouli, Nicolas Papageorgiou, Maria Mate, Bruno Canard, Bruno Coutard, Detlef Bentrop, Georgios Spyroulias

Journal of Molecular Biology 431:2283-2297 (2019)10.1016/j.jmb.2019.04.013

2019
Conformational plasticity of the VEEV macro domain is important for binding of ADP-ribose

Garyfallia Makrynitsa, Dioni Ntonti, Konstantinos Marousis, Maria Birkou, Minos-Timotheos Matsoukas, Sam Asami, Detlef Bentrop, Nicolas Papageorgiou, Bruno Canard, Bruno Coutard, Georgios Spyroulias

Journal of Structural Biology 206:119-127 (2019)10.1016/j.jsb.2019.02.008

2019
Comparative study of chikungunya Virus-Like Particles and Pseudotyped-Particles used for serological detection of specific immunoglobulin M

Gérald Theillet, Jérôme Martinez, Christophe Steinbrugger, Dimitri Lavillette, Bruno Coutard, Nicolas Papageorgiou, Pascal Dalbon, Isabelle Leparc-Goffart, Frederic Bedin

Virology 529:195-204 (2019)10.1016/j.virol.2019.01.027

2019
Structure and oligomerization state of the C-terminal region of the Middle East respiratory syndrome coronavirus nucleoprotein

Thi Hong Van Nguyen, Julie Lichiere, Bruno Canard, Nicolas Papageorgiou, Sarah Attoumani, Francois Ferron, Bruno Coutard

Acta crystallographica Section D : Structural biology [1993-...] 75:8-15 (2019)10.1107/S2059798318014948

2018

2018
Structural and Functional Basis of the Fidelity of Nucleotide Selection by Flavivirus RNA-Dependent RNA Polymerases

Barbara Selisko, Nicolas Papageorgiou, Francois Ferron, Bruno Canard

Viruses 10:59 (2018)10.3390/v10020059

2017

2017
Activity inhibition and crystal polymorphism induced by active-site metal swapping

Elsie yekwa, Joelle Khourieh, Bruno Canard, Nicolas Papageorgiou, Francois Ferron

Acta crystallographica Section D : Structural biology [1993-...] 73:641-649 (2017)10.1107/S205979831700866X

2017
Toscana virus nucleoprotein oligomer organization observed in solution

Amal Baklouti, Adeline Goulet, Julie Lichiere, Bruno Canard, Remi Charrel, Francois Ferron, Bruno Coutard, Nicolas Papageorgiou

Acta crystallographica Section D : Structural biology [1993-...] 73:650-659 (2017)10.1107/S2059798317008774

2016

2016
Coxsackievirus B3 protease 3C: expression, purification, crystallization and preliminary structural insights

Stavroula Fili, Alexandros Valmas, Magdalini Christopoulou, Maria Spiliopoulou, Nikos Nikolopoulos, Julie Lichiere, Souzana Logotheti, Fotini Karavassili, Eleftheria Rosmaraki, Andrew Fitch, Jonathan Wright, Detlef Beckers, Thomas Degen, Gwilherm Nenert, Rolf Hilgenfeld, Nicolas Papageorgiou, Bruno Canard, Bruno Coutard, Irene Margiolaki

Acta crystallographica Section F : Structural biology communications [2014-...] 72:877-884 (2016)10.1107/S2053230X16018513

2016
Structural characterization of the N-terminal part of the MERS-CoV nucleocapsid by X-ray diffraction and small-angle X-ray scattering

Nicolas Papageorgiou, Julie Lichiere, Amal Baklouti, Francois Ferron, Marion Sevajol, Bruno Canard, Bruno Coutard

Acta crystallographica Section D : Structural biology [1993-...] 72:192-202 (2016)10.1107/S2059798315024328

2015

2015
NMR study of non-structural proteins-part II: H-1, C-13, N-15 backbone and side-chain resonance assignment of macro domain from Venezuelan equine encephalitis virus (VEEV)

Garyfallia I. Makrynitsa, Dioni Ntonti, Konstantinos D. Marousis, Aikaterini C. Tsika, Julie Lichiere, Nicolas Papageorgiou, Bruno Coutard, Detlef Bentrop, Georgios A. Spyroulias

BIOMOLECULAR NMR ASSIGNMENTS 9:247-251 (2015)10.1007/s12104-014-9584-9

2015
NMR study of non-structural proteins-part I: H-1, C-13, N-15 backbone and side-chain resonance assignment of macro domain from Mayaro virus (MAYV)

Efstathios Melekis, Aikaterini C. Tsika, Julie Lichiere, Christos T. Chasapis, Irene Margiolaki, Nicolas Papageorgiou, Bruno Coutard, Detlef Bentrop, Georgios A. Spyroulias

BIOMOLECULAR NMR ASSIGNMENTS 9:191-195 (2015)10.1007/s12104-014-9572-0

2013

2013
Atomic resolution description of the interaction between the nucleoprotein and phosphoprotein of Hendra virus.

Guillaume Communie, Johnny Habchi, Filip yabukarski, David Blocquel, Robert Schneider, Nicolas Tarbouriech, Nicolas Papageorgiou, Rob W H Ruigrok, Marc Jamin, Malene Ringkjøbing Jensen, Sonia Longhi, Martin Blackledge

PLoS Pathogens 9:e1003631 (2013)

2011

2011
Crystallization and diffraction analysis of the SARS coronavirus nsp10-nsp16 complex.

Claire Debarnot, Isabelle Imbert, Francois Ferron, Laure Gluais, Isabelle Varlet, Nicolas Papageorgiou, Mickaël Bouvet, Julien Lescar, Etienne Decroly, Bruno Canard

Acta crystallographica Section F : Structural biology communications [2014-...] 67:404-8 (2011)10.1107/S1744309111002867