AFMB collection in HAL: here


Recent expansion of metabolic versatility in Diplonema papillatum, the model species of a highly speciose group of marine eukaryotes

Matus Valach, Sandrine Moreira, Celine Petitjean, Corinna Benz, Anzhelika Butenko, Olga Flegontova, Anna Nenarokova, Galina Prokopchuk, Tom Batstone, Pascal Lapébie, Lionnel Lemogo, Matt Sarrasin, Paul Stretenowich, Pragya Tripathi, Euki Yazaki, Takeshi Nara, Bernard Henrissat, B Franz Lang, Michael Gray, Tom Williams, Julius Lukeš, Gertraud Burger, B. Franz Lang

BMC Biology 21:99 (2023)10.1186/s12915-023-01563-9

Stable functional structure despite high taxonomic variability across fungal communities in soils of old-growth montane forests

Qingchao Zeng, Annie Lebreton, Lucas Auer, Xiaowu Man, Liukun Jia, Gengshen Wang, Sai Gong, Vincent Lombard, Marc Buée, Gang Wu, Yucheng Dai, Zhuliang Yang, Francis M Martin

Microbiome 11:217 (2023)10.1186/s40168-023-01650-7

Structural basis of Ty1 integrase tethering to RNA polymerase III for targeted retrotransposon integration

Phong Quoc Nguyen, Sonia Huecas, Amna Asif-Laidin, Adrián Plaza-Pegueroles, Beatrice Capuzzi, Noé Palmic, Christine Conesa, Joël Acker, Juan Reguera, Pascale Lesage, Carlos Fernández-Tornero

Nature Communications 14:1729 (2023)10.1038/s41467-023-37109-4

Umbrella Data Management Plans to Integrate FAIR Data: Lessons From the ISIDORe and BY-COVID Consortia for Pandemic Preparedness

Romain David, Audrey Richard, Claire Connellan, Katharina Lauer, Maria Luisa Chiusano, Carole Goble, Martin Houde, Isabel Kemmer, Antje Keppler, Philippe Lieutaud, Christian Ohmann, Maria Panagiotopoulou, Sara Raza Khan, Arina Rybina, Stian Soiland-Reyes, Charlotte Wit, Rudolf Wittner, Rafael Andrade Buono, Sarah Arnaud Marsh, Pauline Audergon, Dylan Bonfils, Jose-Maria Carazo, Remi Charrel, Frederik Coppens, Wolfgang Fecke, Claudia Filippone, Eva Garcia Alvarez, Sheraz Gul, Henning Hermjakob, Katja Herzog, Petr Holub, Lukasz Kozera, Allyson Lister, José López-Coronado, Bénédicte Madon, Kurt Majcen, William Martin, Wolfgang Müller, Elli Papadopoulou, Christine M.A. Prat, Paolo Romano, Susanna-Assunta Sansone, Gary Saunders, Niklas Blomberg, Jonathan Ewbank

CODATA Data Science Journal 22:35 (2023)10.5334/dsj-2023-035

The Ustilago maydis AA10 LPMO is active on fungal cell wall chitin

Roseline Assiah Yao, Jean-Lou Reyre, Ketty Tamburrini, Mireille Haon, Olivier Tranquet, Akshay Nalubothula, Saumashish Mukherjee, Sophie Le Gall, Sacha Grisel, Sonia Longhi, Jogi Madhuprakash, Bastien Bissaro, Jean-Guy Berrin

Applied and Environmental Microbiology 89 (2023)10.1128/aem.00573-23

The Human PDZome 2.0: Characterization of a New Resource to Test for PDZ Interactions by Yeast Two-Hybrid

Monica Castro-Cruz, Frédérique Lembo, Jean-Paul Borg, Gilles Travé, Renaud Vincentelli, Pascale Zimmermann

Membranes 13:737 (2023)10.3390/membranes13080737

The ESTHER database on alpha/beta hydrolase fold proteins - An overview of recent developments

Arnaud Chatonnet, Michel Perochon, Eric Velluet, Pascale Marchot

Chemico-Biological Interactions 383:110671 (2023)10.1016/j.cbi.2023.110671

Structures of active Hantaan virus polymerase uncover the mechanisms of Hantaviridae genome replication

Quentin Durieux Trouilleton, Sergio Barata-García, Benoît Arragain, Juan Reguera, Hélène Malet

Nature Communications 14:2954 (2023)10.1038/s41467-023-38555-w

An OMA1 redox site controls mitochondrial homeostasis, sarcoma growth, and immunogenicity

Richard Miallot, Virginie Millet, Yann Groult, Angelika Modelska, Lydie Crescence, Sandrine Roulland, Sandrine Henri, Bernard Malissen, Nicolas Brouilly, Laurence Panicot-Dubois, Renaud Vincentelli, Gerlind Sulzenbacher, Pascal Finetti, Aurélie Dutour, Jean-Yves Blay, François Bertucci, Franck Galland, Philippe Naquet

Life Science Alliance 6 (2023)10.26508/lsa.202201767

Structural basis and dynamics of Chikungunya alphavirus RNA capping by nsP1 capping pores

Rhian Jones, Michael Hons, Nadia Rabah, Noelia Zamarreño, Rocío Arranz, Juan Reguera

Proceedings of the National Academy of Sciences of the United States of America 120 (2023)10.1073/pnas.2213934120

Discovery of a PDZ Domain Inhibitor Targeting the Syndecan/Syntenin Protein–Protein Interaction: A Semi-Automated “Hit Identification-to-Optimization” Approach

Laurent Hoffer, Manon Garcia, Raphael Leblanc, Mikael Feracci, Stéphane Betzi, Khaoula Ben Yaala, Avais Daulat, Pascale Zimmermann, Philippe Roche, Karine Barral, Xavier Morelli

Journal of Medicinal Chemistry (2023)10.1021/acs.jmedchem.2c01569

A global phylogenomic analysis of the shiitake genus Lentinula

Sean Sierra-Patev, Byoungnam Min, Miguel Naranjo-Ortiz, Brian Looney, Zachary Konkel, Jason Slot, Yuichi Sakamoto, Jacob Steenwyk, Antonis Rokas, Juan Carro, Susana Camarero, Patricia Ferreira, Gonzalo Molpeceres, Francisco Ruiz-Dueñas, Ana Serrano, Bernard Henrissat, Elodie Drula, Karen Hughes, Juan Mata, Noemia Kazue Ishikawa, Ruby Vargas-Isla, Shuji Ushijima, Chris Smith, John Donoghue, Steven Ahrendt, William Andreopoulos, Guifen He, Kurt Labutti, Anna Lipzen, Vivian Ng, Robert Riley, Laura Sandor, Kerrie Barry, Angel Martínez, Yang Xiao, John Gibbons, Kazuhisa Terashima, Igor Grigoriev, David Hibbett

Proceedings of the National Academy of Sciences of the United States of America 120:e2214076120 (2023)10.1073/pnas.2214076120

Speciation Underpinned by Unexpected Molecular Diversity in the Mycorrhizal Fungal Genus Pisolithus

Jonathan M Plett, Shingo Miyauchi, Emmanuelle Morin, Krista Plett, Johanna Wong-Bajracharya, Maira de Freitas Pereira, Alan Kuo, Bernard Henrissat, Elodie Drula, Dominika Wojtalewicz, Robert Riley, Jasmyn Pangilinan, William Andreopoulos, Kurt Labutti, Chris Daum, Yuko Yoshinaga, Laure Fauchery, Vivian Ng, Anna Lipzen, Kerrie Barry, Vasanth Singan, Jie Guo, Teresa Lebel, Mauricio Dutra Costa, Igor V Grigoriev, Francis Martin, Ian C Anderson, Annegret Kohler

Molecular Biology and Evolution 40:msad045 (2023)10.1093/molbev/msad045

Interplay of RNA 2′-O-methylations with viral replication

Alice Decombe, Priscila El Kazzi, Etienne Decroly

Current Opinion in Virology 59:101302 (2023)10.1016/j.coviro.2023.101302

Guidelines for the Simulations of Nitroxide X-Band cw EPR Spectra from Site-Directed Spin Labeling Experiments Using SimLabel

Emilien Etienne, Annalisa Pierro, Ketty C Tamburrini, Alessio Bonucci, Elisabetta Mileo, Marlène Martinho, Valérie Belle

Molecules 28:1348 (2023)10.3390/molecules28031348

Design and synthesis of naturally-inspired SARS-CoV-2 inhibitors

Haitham Hassan, Jeanne Chiavaralli, Afnan Hassan, Loay Bedda, Tim Krischuns, Kuang-Yu Chen, Alice Shi Ming Li, Adrien Delpal, Etienne Decroly, Masoud Vedadi, Nadia Naffakh, Fabrice Agou, Sergio Mallart, Reem Arafa, Paola Arimondo

RSC Medicinal Chemistry 14:507-519 (2023)10.1039/D2MD00149G

Biochemistry of the Respiratory Syncytial Virus L Protein Embedding RNA Polymerase and Capping Activities

Priscila Sutto-Ortiz, Jean-François Eléouët, François Ferron, Etienne Decroly

Viruses 15:341 (2023)10.3390/v15020341

Liaisons dangereuses: Intrinsic Disorder in Cellular Proteins Recruited to Viral Infection-Related Biocondensates

Greta Bianchi, Stefania Brocca, Sonia Longhi, Vladimir N Uversky

International Journal of Molecular Sciences 24:2151 (2023)10.3390/ijms24032151

A subfamily classification to choreograph the diverse activities within glycoside hydrolase family 31

Thimali Arumapperuma, Jinling Li, Bastian Hornung, Niccolay Madiedo Soler, Ethan Goddard-Borger, Nicolas Terrapon, Spencer Williams

Journal of Biological Chemistry 299:103038 (2023)10.1016/j.jbc.2023.103038

AT-752 targets multiple sites and activities on the Dengue virus replication enzyme NS5

Mikael Feracci, Cécilia Eydoux, Véronique Fattorini, Lea Lo Bello, Pierre Gauffre, Barbara Selisko, Priscila Sutto-Ortiz, Ashleigh Shannon, Hongjie Xia, Pei-Yong Shi, Mathieu Noel, Françoise Debart, Jean-Jacques Vasseur, Steve Good, Kai Lin, Adel Moussa, Jean-Pierre Sommadossi, Aurélie Chazot, Karine Alvarez, Jean-Claude Guillemot, Etienne Decroly, François Ferron, Bruno Canard

Antiviral Research 212:105574 (2023)10.1016/j.antiviral.2023.105574

An HMM approach expands the landscape of sesquiterpene cyclases across the kingdom Fungi

Hayat Hage, Julie Couillaud, Asaf Salamov, Margot Loussouarn-Yvon, Fabien Durbesson, Elena Ormeño, Sacha Grisel, Katia Duquesne, Renaud Vincentelli, Igor Grigoriev, Gilles Iacazio, Marie-Noëlle Rosso

Microbial Genomics 9:000990 (2023)10.1099/mgen.0.000990

Molecular Determinants of Fibrillation in a Viral Amyloidogenic Domain from Combined Biochemical and Biophysical Studies

Juliet F Nilsson, Hakima Baroudi, Frank Gondelaud, Giulia Pesce, Christophe Bignon, Denis Ptchelkine, Joseph Chamieh, Hervé Cottet, Andrey V Kajava, Sonia Longhi

International Journal of Molecular Sciences 24:399 (2023)10.3390/ijms24010399

Activity and Crystal Structure of the Adherent-Invasive Escherichia coli Tle3/Tli3 T6SS Effector/Immunity Complex Determined Using an AlphaFold2 Predicted Model

Thi Thu Hang Le, Christine Kellenberger, Marie Boyer, Pierre Santucci, Nicolas Flaugnatti, Eric Cascales, Alain Roussel, Stéphane Canaan, Laure Journet, Christian Cambillau

International Journal of Molecular Sciences 24:1740 (2023)10.3390/ijms24021740

Macro1 domain residue F156: A hallmark of SARS-CoV-2 de-MARylation specificity

Oney Ortega Granda, Karine Alvarez, Maria J Mate-Perez, Bruno Canard, François Ferron, Nadia Rabah

Virology 587:109845 (2023)10.1016/j.virol.2023.109845

Per Aspera ad Chaos: Vladimir Uversky’s Odyssey through the Strange World of Intrinsically Disordered Proteins

Prakash Kulkarni, Stefania Brocca, A. Keith Dunker, Sonia Longhi

Biomolecules 13:1015 (2023)10.3390/biom13061015

Amino Acid Polymorphisms on the Brazilian Strain of Yellow Fever Virus Methyltransferase Are Related to the Host’s Immune Evasion Mediated by Type I Interferon

Nathália Dias Furtado, Iasmim Silva de Mello, Andre Schutzer de Godoy, Gabriela Dias Noske, Glaucius Oliva, Bruno Canard, Etienne Decroly, Myrna Bonaldo

Viruses 15:191 (2023)10.3390/v15010191

Minimum information guidelines for experiments structurally characterizing intrinsically disordered protein regions

Bálint Mészáros, András Hatos, Nicolas Palopoli, Federica Quaglia, Edoardo Salladini, Kim van Roey, Haribabu Arthanari, Zsuzsanna Dosztányi, Isabella C Felli, Patrick D Fischer, Jeffrey C Hoch, Cy M Jeffries, Sonia Longhi, Emiliano Maiani, Sandra Orchard, Rita Pancsa, Elena Papaleo, Roberta Pierattelli, Damiano Piovesan, Iva Pritisanac, Luiggi Tenorio, Thibault Viennet, Peter Tompa, Wim Vranken, Silvio C E Tosatto, Norman E Davey

Nature Methods (2023)10.1038/s41592-023-01915-x

Conidium Specific Polysaccharides in Aspergillus fumigatus

Zhonghua Liu, Isabel Valsecchi, Rémy A Le Meur, Catherine Simenel, J. Iñaki Guijarro, Catherine Comte, Laetitia Muszkieta, Isabelle Mouyna, Bernard Henrissat, Vishukumar Aimanianda, Jean-Paul Latgé, Thierry Fontaine

Journal of Fungi 9:155 (2023)10.3390/jof9020155

Structure-guided optimization of adenosine mimetics as selective and potent inhibitors of coronavirus nsp14 N7-methyltransferases

Marcel Hausdorff, Adrien Delpal, Sarah Barelier, Laura Nicollet, Bruno Canard, Franck Touret, Agathe Colmant, Bruno Coutard, Jean-Jacques Vasseur, Etienne Decroly, Françoise Debart

European Journal of Medicinal Chemistry (2023)10.1016/j.ejmech.2023.115474

Fluorescence polarisation activity-based protein profiling for the identification of deoxynojirimycin-type inhibitors selective for lysosomal retaining alpha- and beta-glucosidases

Daniël van der Gracht, Rhianna J Rowland, Véronique Roig-Zamboni, Maria J Ferraz, Max Louwerse, Paul P Geurink, Johannes M F G Aerts, Gerlind Sulzenbacher, Gideon J Davies, Herman S Overkleeft, Marta Artola

Chemical Science 14:9136-9144 (2023)10.1039/d3sc01021j

Light-inducible T cell engagers trigger, tune and shape the activation of primary T cells

Morgane Jaeger, Amandine Anastasio, Léa Chamy, Sophie Brustlein, Renaud Vincentelli, Fabien Durbesson, Julien Gigan, Morgane Thépaut, Rémy Char, Maud Boussand, Mathias Lechelon, Rafael Argüello, Didier Marguet, Hai-Tao He, Rémi Lasserre

Proceedings of the National Academy of Sciences of the United States of America 120:e2302500120 (2023)10.1073/pnas.2302500120