Degrees

– 2021 Habilitation to Supervise Research (HDR). Life and health sciences. University of Toulon.

– 2007 Doctoral thesis (Ph.D.) Division of Experimental Medicine. McGill University. Montreal. Canada.

– 2000 Bachelor’s degree (B.Sc.) Molecular biology and biotechnology. University of Quebec at Montreal (UQAM). Montreal. Canada.

Professional experience

– 2014 – Lecturer. University of Toulon- AMU- AFMB (Architecture and Function of biological macromolecules). Marseille. France.  “Elucidation of biochemical and molecular mechanisms involved in processes related to viral infections due to RNA viruses”.

Project 1: Functional characterization of the different methyl and guanylyl transferase activities of alpha-like viruses.

Project 2: Study of the role of ORF 1 proteins of hepatitis E virus (HEV) in viral escape.

Project 3 : Macro domain as a new target for antiviral development in polarity-positive RNA viruses.

– 2010 -2013 Associate Professor. University of Toulon- MAPIEM (Materials – Polymers – Interfaces – Marine Environment). Toulon. France.  “New approach against biofouling: Targeting the bacterial communication system (Quorum Sensing)”.

– 2009 – 2010 Researcher-postdoc CNRS-AFMB (Architecture and function of biological macromolecules). Marseille. France. “Involvement of Alphavirus non-structural proteins in viral escape: Applications as new targets for antiviral agents”.

– 2008 -2009 Researcher-postdoc Institut Paoli Calmettes-INSERM. Marseille. France. “Biomarkers: from fundamental discovery to targeted therapies in cancerology”.

– 2007 Researcher-doctoral fellow Clinical Research Institute of Montreal. Montreal. Canada. “Production and molecular characterization of the pro-protein convertase1/3”.

Publications

2021

2021
Structure and Sequence Requirements for RNA Capping at the Venezuelan Equine Encephalitis Virus RNA 5′ End

Oney Ortega Granda, Coralie Valle, Ashleigh Shannon, Etienne Decroly, Bruno Canard, Bruno Coutard, Nadia Rabah

Journal of Virology 95 (2021)10.1128/JVI.00777-21

2020

2020
Mutations on VEEV nsP1 relate RNA capping efficiency to ribavirin susceptibility

Nadia Rabah, Oney Ortega Granda, Gilles Quérat, Bruno Canard, Etienne Decroly, Bruno Coutard

Antiviral Research 182:104883 (2020)10.1016/j.antiviral.2020.104883

2015

2015
Arenavirus Glycan Shield Promotes Neutralizing Antibody Evasion and Protracted Infection

Rami Sommerstein, Lukas Flatz, Melissa M. Remy, Pauline Malinge, Giovanni Magistrelli, Nicolas Fischer, Mehmet Sahin, Andreas Bergthaler, Sebastien Igonet, Jan Ter Meulen, Dorothee Rigo, Paolo Meda, Nadia Rabah, Bruno Coutard, Thomas A. Bowden, Paul-Henri Lambert, Claire-Anne Siegrist, Daniel D. Pinschewer

PLoS Pathogens 11 (2015)10.1371/journal.ppat.1005276

2015
mRNA Capping by Venezuelan Equine Encephalitis Virus nsP1: Functional Characterization and Implications for Antiviral Research

Changqing Li, Jaime Guillen, Nadia Rabah, Alexandre Blanjoie, Francoise Debart, Jean-Jacques Vasseur, Bruno Canard, Etienne Decroly, Bruno Coutard

Journal of Virology 89:8292-8303 (2015)10.1128/JVI.00599-15

2015
Structural and biophysical analysis of sequence insertions in the Venezuelan Equine Encephalitis Virus macro domain

Jaime Guillen, Julie Lichiere, Nadia Rabah, Brett F. Beitzel, Bruno Canard, Bruno Coutard

Virus Research 201:94-100 (2015)10.1016/j.virusres.2015.02.018