J. Reguera’s team guest: Marta Pérez Illana, ITQB NOVA Portugal – Webinar postponed

Abstract

Marta Pérez Illana is a postdoc working on a collaboration research at Margarida Archer (ITQB NOVA, Portugal) and Roberto Lins (Fiocruz Pernambuco, Brazil) groups in the project “Computational design and 3D structure of peptides neutralizing arboviruses: battling Dengue, Zika and Chikungunya”. Their main goal is to design, synthesize and characterize the stability and neutralization potential of novel synthetic engineered proteins with mimicking/improved antibody-like functions, and elucidate their 3D structures in complex with their targets (isolated viral proteins or whole viral particles) by X-ray and cryo-EM, to provide high resolution data on  the molecular  interactions at the interfaces. These synthetic proteins could be potential biopharmaceuticals to be used for diagnosis, prophylaxis or treatments.