Bhawna Sama
Postdoctoral fellow
Research group: Viral Replicases: Structure, function and drug-design
Publications
2024
The effects of Remdesivir's functional groups on its antiviral potency and resistance against the SARS-CoV-2 polymerase
Bhawna Sama, Barbara Selisko, Camille Falcou, Véronique Fattorini, Géraldine Piorkowski, Franck Touret, Kim Donckers, Johan Neyts, Dirk Jochmans, Ashleigh Shannon, Bruno Coutard, Bruno Canard
Antiviral Research 232 (2024)10.1016/j.antiviral.2024.106034
2022
A second type of N7-guanine RNA cap methyltransferase in an unusual locus of a large RNA virus genome
Ashleigh Shannon, Bhawna Sama, Pierre Gauffre, Théo Guez, Françoise Debart, Jean-Jacques Vasseur, Etienne Decroly, Bruno Canard, François Ferron
Nucleic Acids Research 50:11186-11198 (2022)10.1093/nar/gkac876
A dual mechanism of action of AT-527 against SARS-CoV-2 polymerase
Ashleigh Shannon, Véronique Fattorini, Bhawna Sama, Barbara Selisko, Mikael Feracci, Camille Falcou, Pierre Gauffre, Priscila El Kazzi, Adrien Delpal, Etienne Decroly, Karine Alvarez, Cécilia Eydoux, Jean-Claude Guillemot, Adel Moussa, Steven S Good, Paolo La Colla, Kai Lin, Jean-Pierre Sommadossi, Yingxiao Zhu, Xiaodong Yan, Hui Shi, Francois Ferron, Bruno Canard
Nature Communications 13 (2022)10.1038/s41467-022-28113-1
2021
The enzymes for genome size increase and maintenance of large (+)RNA viruses
Francois Ferron, Bhawna Sama, Etienne Decroly, Bruno Canard
Trends in Biochemical Sciences (2021)10.1016/j.tibs.2021.05.006
