Nicolas Terrapon
Assistant professor
Research group: GlycogenomicsGroup leader
Correspondent seminars/webinars 2023-…
Publications
2024
Candidate genes involved in biosynthesis and degradation of the main extracellular matrix polysaccharides of brown algae and their probable evolutionary history
Lisa Mazéas, Ahlem Bouguerba-Collin, J. Mark Cock, France Denoeud, Olivier Godfroy, Loraine Brillet-Guéguen, Tristan Barbeyron, Agnieszka Lipinska, Ludovic Delage, Erwan Corre, Elodie Drula, Bernard Henrissat, Mirjam Czjzek, Nicolas Terrapon, Cécile Hervé
BMC Genomics 25:950 (2024)10.1186/s12864-024-10811-3
Ruminococcus torques is a keystone degrader of intestinal mucin glycoprotein, releasing oligosaccharides used by Bacteroides thetaiotaomicron
Sadie Schaus, Gabriel Vasconcelos Pereira, Ana Luis, Emily Madlambayan, Nicolas Terrapon, Matthew Ostrowski, Chunsheng Jin, Bernard Henrissat, Gunnar Hansson, Eric Martens
mBio 15:e0003924 (2024)10.1128/mbio.00039-24
Two newly established and mutually related subfamilies GH13_48 and GH13_49 of the α-amylase family GH13
Filip Mareček, Nicolas Terrapon, Štefan Janeček
Applied Microbiology and Biotechnology 108:415 (2024)10.1007/s00253-024-13251-x
Elizabethkingia anophelis MSU001 Isolated from Anopheles stephensi: Molecular Characterization and Comparative Genome Analysis
Shicheng Chen, Steven Pham, Nicolas Terrapon, Jochen Blom, Edward Walker
Microorganisms 12:1079 (2024)10.3390/microorganisms12061079
Unveiling the role of novel carbohydrate‐binding modules in laminarin interaction of multimodular proteins from marine Bacteroidota during phytoplankton blooms
Marie-Katherin Zühlke, Elizabeth Ficko-Blean, Daniel Bartosik, Nicolas Terrapon, Alexandra Jeudy, Murielle Jam, Fengqing Wang, Norma Welsch, Alexandra Dürwald, Laura Torres Martin, Robert Larocque, Diane Jouanneau, Tom Eisenack, François Thomas, Anke Trautwein-Schult, Hanno Teeling, Dörte Becher, Thomas Schweder, Mirjam Czjzek
Environmental Microbiology 26:e16624 (2024)10.1111/1462-2920.16624
Prevotella copri and microbiota members mediate the beneficial effects of a therapeutic food for malnutrition
Hao-Wei Chang, Evan Lee, Yi Wang, Cyrus Zhou, Kali Pruss, Suzanne Henrissat, Robert Chen, Clara Kao, Matthew Hibberd, Hannah Lynn, Daniel Webber, Marie Crane, Jiye Cheng, Dmitry Rodionov, Aleksandr Arzamasov, Juan Castillo, Garret Couture, Ye Chen, Nikita Balcazo, Carlito Lebrilla, Nicolas Terrapon, Bernard Henrissat, Olga Ilkayeva, Michael Muehlbauer, Christopher Newgard, Ishita Mostafa, Subhasish Das, Mustafa Mahfuz, Andrei Osterman, Michael Barratt, Tahmeed Ahmed, Jeffrey Gordon
Nature Microbiology 9:922-937 (2024)10.1038/s41564-024-01628-7
Evolutionary genomics of the emergence of brown algae as key components of coastal ecosystems
France Denoeud, Olivier Godfroy, Corinne Cruaud, Svenja Heesch, Zofia Nehr, Nachida Tadrent, Arnaud Couloux, Loraine Brillet-Guéguen, Ludovic Delage, Dean Mckeown, Taizo Motomura, Duncan Sussfeld, Xiao Fan, Lisa Mazéas, Nicolas Terrapon, Josué Barrera-Redondo, Romy Petroll, Lauric Reynes, Seok-Wan Choi, Jihoon Jo, Kavitha Uthanumallian, Kenny Bogaert, Céline Duc, Pélagie Ratchinski, Agnieszka Lipinska, Benjamin Noel, Eleanor Murphy, Martin Lohr, Ananya Khatei, Pauline Hamon-Giraud, Christophe Vieira, Komlan Avia, Svea Sanja Akerfors, Shingo Akita, Yacine Badis, Tristan Barbeyron, Arnaud Belcour, Wahiba Berrabah, Samuel Blanquart, Ahlem Bouguerba-Collin, Trevor Bringloe, Rose Ann Cattolico, Alexandre Cormier, Helena Cruz de Carvalho, Romain Dallet, Olivier de Clerck, Ahmed Debit, Erwan Denis, Christophe Destombe, Erica Dinatale, Simon Dittami, Elodie Drula, Sylvain Faugeron, Jeanne Got, Louis Graf, Agnès Groisillier, Marie-Laure Guillemin, Lars Harms, William John Hatchett, Bernard Henrissat, Galice Hoarau, Chloé Jollivet, Alexander Jueterbock, Ehsan Kayal, Andrew Knoll, Kazuhiro Kogame, Arthur Le Bars, Catherine Leblanc, Line Le Gall, Ronja Ley, Xi Liu, Steven Loduca, Pascal Jean Lopez, Philippe Lopez, Eric Manirakiza, Karine Massau, Stéphane Mauger, Laetitia Mest, Gurvan Michel, Catia Monteiro, Chikako Nagasato, Delphine Nègre, Eric Pelletier, Naomi Phillips, Philippe Potin, Stefan Rensing, Ellyn Rousselot, Sylvie Rousvoal, Declan Schroeder, Delphine Scornet, Anne Siegel, Leila Tirichine, Thierry Tonon, Klaus Valentin, Heroen Verbruggen, Florian Weinberger, Glen Wheeler, Hiroshi Kawai, Akira Peters, Hwan Su Yoon, Cécile Hervé, Naihao Ye, Eric Bapteste, Myriam Valero, Gabriel Markov, Erwan Corre, Susana Coelho, Patrick Wincker, Jean-Marc Aury, J. Mark Cock
Cell (2024)10.1016/j.cell.2024.10.049
2023
Bioactive glycans in a microbiome-directed food for children with malnutrition
Matthew Hibberd, Daniel Webber, Dmitry Rodionov, Suzanne Henrissat, Robert Chen, Cyrus Zhou, Hannah Lynn, Yi Wang, Hao-Wei Chang, Evan Lee, Janaki Lelwala-Guruge, Marat Kazanov, Aleksandr Arzamasov, Semen Leyn, Vincent Lombard, Nicolas Terrapon, Bernard Henrissat, Juan Castillo, Garret Couture, Nikita Bacalzo, Ye Chen, Carlito Lebrilla, Ishita Mostafa, Subhasish Das, Mustafa Mahfuz, Michael Barratt, Andrei Osterman, Tahmeed Ahmed, Jeffrey Gordon
Nature 625:157-165 (2023)10.1038/s41586-023-06838-3
Bioactive glycans in a microbiome-directed food for children with malnutrition
Matthew Hibberd, Daniel Webber, Dmitry Rodionov, Suzanne Henrissat, Robert Chen, Cyrus Zhou, Hannah Lynn, Yi Wang, Hao-Wei Chang, Evan Lee, Janaki Lelwala-Guruge, Marat Kazanov, Aleksandr Arzamasov, Semen Leyn, Vincent Lombard, Nicolas Terrapon, Bernard Henrissat, Juan Castillo, Garret Couture, Nikita Bacalzo, Ye Chen, Carlito Lebrilla, Ishita Mostafa, Subhasish Das, Mustafa Mahfuz, Michael Barratt, Andrei Osterman, Tahmeed Ahmed, Jeffrey Gordon
Nature 625:157-165 (2023)10.1038/s41586-023-06838-3
Bioactive glycans in a microbiome-directed food for children with malnutrition
Matthew Hibberd, Daniel Webber, Dmitry Rodionov, Suzanne Henrissat, Robert Chen, Cyrus Zhou, Hannah Lynn, Yi Wang, Hao-Wei Chang, Evan Lee, Janaki Lelwala-Guruge, Marat Kazanov, Aleksandr Arzamasov, Semen Leyn, Vincent Lombard, Nicolas Terrapon, Bernard Henrissat, Juan Castillo, Garret Couture, Nikita Bacalzo, Ye Chen, Carlito Lebrilla, Ishita Mostafa, Subhasish Das, Mustafa Mahfuz, Michael Barratt, Andrei Osterman, Tahmeed Ahmed, Jeffrey Gordon
Nature 625:157-165 (2023)10.1038/s41586-023-06838-3
Hadza Prevotella require diet-derived microbiota-accessible carbohydrates to persist in mice
Rebecca Gellman, Matthew Olm, Nicolas Terrapon, Fatima Enam, Steven Higginbottom, Justin Sonnenburg, Erica Sonnenburg
Cell Reports 42:113233 (2023)10.1016/j.celrep.2023.113233
Inducible CRISPR-targeted “knockdown” of human gut Bacteroides in gnotobiotic mice discloses glycan utilization strategies
Zachary Beller, Darryl Wesener, Timothy Seebeck, Janaki Guruge, Alexandra Byrne, Suzanne Henrissat, Nicolas Terrapon, Bernard Henrissat, Dmitry Rodionov, Andrei Osterman, Chris Suarez, Nikita Bacalzo, Ye Chen, Garret Couture, Carlito Lebrilla, Zhigang Zhang, Erik Eastlund, Caitlin Mccann, Gregory Davis, Jeffrey Gordon
Proceedings of the National Academy of Sciences of the United States of America 120:e2311422120 (2023)10.1073/pnas.2311422120
Novel laminarin-binding CBMs in multimodular proteins of marine Bacteroidota feature prominently in phytoplankton blooms
Marie-Katherin Zühlke, Elizabeth Ficko-Blean, Daniel Bartosik, Nicolas Terrapon, Alexandra Jeudy, Murielle Jam, Fengqing Wang, Norma Welsch, Robert Larocque, Diane Jouanneau, Tom Eisenack, François Thomas, Anke Trautwein-Schult, Hanno Teeling, Dörte Becher, Thomas Schweder, Mirjam Czjzek
BioRxiv (2023)10.1101/2023.09.07.556657
BoGH13ASus from Bacteroides ovatus represents a novel α-amylase used for Bacteroides starch breakdown in the human gut
Haley Brown, Anna Deveaux, Brock Juliano, Amanda Photenhauer, Matthieu Boulinguiez, Russell Bornschein, Zdzislaw Wawrzak, Brandon Ruotolo, Nicolas Terrapon, Nicole Koropatkin
Cellular and Molecular Life Sciences 80:232 (2023)10.1007/s00018-023-04812-w
A subfamily classification to choreograph the diverse activities within glycoside hydrolase family 31
Thimali Arumapperuma, Jinling Li, Bastian Hornung, Niccolay Madiedo Soler, Ethan Goddard-Borger, Nicolas Terrapon, Spencer Williams
Journal of Biological Chemistry 299:103038 (2023)10.1016/j.jbc.2023.103038
Taxonomic composition and carbohydrate-active enzyme content in microbial enrichments from pulp mill anaerobic granules after cultivation on lignocellulosic substrates
Mabel T Wong, Camilla L Nesbø, Weijun Wang, Marie Couturier, Vincent Lombard, Pascal Lapebie, Nicolas Terrapon, Bernard Henrissat, Elizabeth A Edwards, Emma R Master
Frontiers in Microbiomes 2:1094865 (2023)10.3389/frmbi.2023.1094865
An objective criterion to evaluate sequence-similarity networks helps in dividing the protein family sequence space
Bastian Volker Helmut Hornung, Nicolas Terrapon
PLoS Computational Biology 19:e1010881 (2023)10.1371/journal.pcbi.1010881
2022
Gut microbiome of the largest living rodent harbors unprecedented enzymatic systems to degrade plant polysaccharides
Lucelia Cabral, Gabriela Persinoti, Douglas Paixão, Marcele Martins, Mariana Morais, Mariana Chinaglia, Mariane Domingues, Mauricio Sforca, Renan Pirolla, Wesley Generoso, Clelton Santos, Lucas Maciel, Nicolas Terrapon, Vincent Lombard, Bernard Henrissat, Mario Murakami
Nature Communications 13:629 (2022)10.1038/s41467-022-28310-y
Gut microbiome of the largest living rodent harbors unprecedented enzymatic systems to degrade plant polysaccharides
Lucelia Cabral, Gabriela Persinoti, Douglas Paixão, Marcele Martins, Mariana Morais, Mariana Chinaglia, Mariane Domingues, Mauricio Sforca, Renan Pirolla, Wesley Generoso, Clelton Santos, Lucas Maciel, Nicolas Terrapon, Vincent Lombard, Bernard Henrissat, Mario Murakami
Nature Communications 13:629 (2022)10.1038/s41467-022-28310-y
Glycoside hydrolase subfamily GH5_57 features a highly redesigned catalytic interface to process complex hetero-β-mannans
Marcele Martins, Mariana Morais, Gabriela Persinoti, Rafael Galinari, Li Yu, Yoshihisa Yoshimi, Fernanda Passos Nunes, Tatiani Lima, Shayla Barbieri, Joana Silveira, Vincent Lombard, Nicolas Terrapon, Paul Dupree, Bernard Henrissat, Mário Murakami
Acta crystallographica Section D : Structural biology [1993-...] 78:1358-1372 (2022)10.1107/S2059798322009561
Glycoside hydrolase subfamily GH5_57 features a highly redesigned catalytic interface to process complex hetero-β-mannans
Marcele Martins, Mariana Morais, Gabriela Persinoti, Rafael Galinari, Li Yu, Yoshihisa Yoshimi, Fernanda Passos Nunes, Tatiani Lima, Shayla Barbieri, Joana Silveira, Vincent Lombard, Nicolas Terrapon, Paul Dupree, Bernard Henrissat, Mário Murakami
Acta crystallographica Section D : Structural biology [1993-...] 78:1358-1372 (2022)10.1107/S2059798322009561
Microbial liberation of N-methylserotonin from orange fiber in gnotobiotic mice and humans
Nathan Han, Jiye Cheng, Omar Delannoy-Bruno, Daniel Webber, Nicolas Terrapon, Bernard Henrissat, Dmitry Rodionov, Aleksandr Arzamasov, Andrei Osterman, David Hayashi, Alexandra Meynier, Sophie Vinoy, Chandani Desai, Stacey Marion, Michael Barratt, Andrew Heath, Jeffrey Gordon
Cell 185:3056-3057 (2022)10.1016/j.cell.2022.07.007
Functional exploration of the glycoside hydrolase family GH113
Marie Couturier, Mélanie Touvrey-Loiodice, Nicolas Terrapon, Elodie Drula, Laurine Buon, Christine Chirat, Bernard Henrissat, William Helbert
PLoS ONE 17:1-14 (2022)10.1371/journal.pone.0267509
Assembly and synthesis of the extracellular matrix in brown algae
Lisa Mazéas, Rina Yonamine, Tristan Barbeyron, Bernard Henrissat, Elodie Drula, Nicolas Terrapon, Chikako Nagasato, Cécile Hervé
Seminars in Cell and Developmental Biology 134:112-124 (2022)10.1016/j.semcdb.2022.03.005
Phenotypic and Genomic Diversification in Complex Carbohydrate-Degrading Human Gut Bacteria
Nicholas Pudlo, Karthik Urs, Ryan Crawford, Ali Pirani, Todd Atherly, Roberto Jimenez, Nicolas Terrapon, Bernard Henrissat, Daniel Peterson, Cherie Ziemer, Evan Snitkin, Eric Martens
mSystems 7:e0094721 (2022)10.1128/msystems.00947-21
The carbohydrate-active enzyme database: functions and literature
Elodie Drula, Marie-Line Garron, Suzan Dogan, Vincent Lombard, Bernard Henrissat, Nicolas Terrapon
Nucleic Acids Research 50:D571-D577 (2022)10.1093/nar/gkab1045
The carbohydrate-active enzyme database: functions and literature
Elodie Drula, Marie-Line Garron, Suzan Dogan, Vincent Lombard, Bernard Henrissat, Nicolas Terrapon
Nucleic Acids Research 50:D571-D577 (2022)10.1093/nar/gkab1045
2021
Polysaccharide utilization loci-driven enzyme discovery reveals BD-FAE: a bifunctional feruloyl and acetyl xylan esterase active on complex natural xylans
Lisanne Hameleers, Leena Penttinen, Martina Ikonen, Léa Jaillot, Régis Fauré, Nicolas Terrapon, Peter J Deuss, Nina Hakulinen, Emma R Master, Edita Jurak
Biotechnology for Biofuels 14 (2021)10.1186/s13068-021-01976-0
Genome Features of Asaia sp. W12 Isolated from the Mosquito Anopheles stephensi Reveal Symbiotic Traits
Shicheng Chen, Ting Yu, Nicolas Terrapon, Bernard Henrissat, Edward D Walker
Genes 12:752 (2021)10.3390/genes12050752
Strain-level functional variation in the human gut microbiota based on bacterial binding to artificial food particles
Michael Patnode, Janaki Guruge, Juan Castillo, Garret Couture, Vincent Lombard, Nicolas Terrapon, Bernard Henrissat, Carlito Lebrilla, Jeffrey Gordon
Cell Host & Microbe 29:664-673.e5 (2021)10.1016/j.chom.2021.01.007
Bioinformatic Analysis of Lytic Polysaccharide Monooxygenases Reveals the Pan-Families Occurrence of Intrinsically Disordered C-Terminal Extensions
Ketty C Tamburrini, Nicolas Terrapon, Vincent Lombard, Bastien Bissaro, Sonia Longhi, Jean-Guy Berrin
Biomolecules 11:1632 (2021)10.3390/biom11111632
2020
Microbiota-directed fibre activates both targeted and secondary metabolic shifts in the distal gut
Leszek Michalak, John Christian Gaby, Leidy Lagos, Sabina Leanti La Rosa, Torgeir Hvidsten, Catherine Tétard-Jones, William G T Willats, Nicolas Terrapon, Vincent Lombard, Bernard Henrissat, Johannes Dröge, Magnus Øverlie Arntzen, Live Heldal Hagen, Margareth Øverland, Phillip Pope, Bjørge Westereng
Nature Communications 11 (2020)10.1038/s41467-020-19585-0
Metabolism of multiple glycosaminoglycans by Bacteroides thetaiotaomicron is orchestrated by a versatile core genetic locus
Didier Ndeh, Arnaud Baslé, Henrik Strahl, Urszula Mcclurgg, Bernard Henrissat, Nicolas Terrapon, Alan Cartmell
Nature Communications 11 (2020)10.1038/s41467-020-14509-4
Isolation and Characterization of Extracellular Vesicles Secreted In Vitro by Porcine Microbiota
Leidy Lagos, Sabina Leanti La Rosa, Magnus Ø. Arntzen, Ragnhild Ånestad, Nicolas Terrapon, John Christian Gaby, Bjørge Westereng
Microorganisms 8:983 (2020)10.3390/microorganisms8070983
A catalog of microbial genes from the bovine rumen unveils a specialized and diverse biomass-degrading environment
Junhua Li, Huanzi Zhong, Yuliaxis Y. Ramayo-Caldas, Nicolas Terrapon, Vincent Lombard, Gabrielle Potocki-Veronese, Jordi Estellé, Milka Popova, Ziyi Yang, Hui Zhang, Fang Li, Shanmei Tang, Fangming Yang, Weineng Chen, Bing Chen, Jiyang Li, Jing Guo, Cécile Martin, Emmanuelle Maguin, Xun Xu, Huanming Yang, Jian Wang, Lise Madsen, Karsten Kristiansen, Bernard Henrissat, Stanislav S. Ehrlich, Diego Morgavi
GigaScience 9:1-15 (2020)10.1093/gigascience/giaa057
Analysis of the diversity of the glycoside hydrolase family 130 in mammal gut microbiomes reveals a novel mannoside-phosphorylase function
Ao Li, Elisabeth Laville, Laurence Tarquis, Vincent Lombard, David Ropartz, Nicolas Terrapon, Bernard Henrissat, David Guieysse, Jeremy Esque, Julien Durand, Diego Morgavi, Gabrielle Potocki-Veronese
Microbial Genomics 6:1-14 (2020)10.1099/mgen.0.000404
Investigating host-microbiome interactions by droplet based microfluidics
Alexandra S Tauzin, Mariana Rangel Pereira, Liisa D van Vliet, Pierre-Yves Colin, Elisabeth Laville, Jeremy Esque, Sandrine Laguerre, Bernard Henrissat, Nicolas Terrapon, Vincent Lombard, Marion Leclerc, Joël Doré, Florian Hollfelder, Gabrielle Potocki-Veronese
Microbiome 8 (2020)10.1186/s40168-020-00911-z
Harvesting of Prebiotic Fructooligosaccharides by Nonbeneficial Human Gut Bacteria
Zhi Wang, Alexandra S. Tauzin, Elisabeth Laville, Pietro Tedesco, Fabien Letisse, Nicolas Terrapon, Pascale Lepercq, Myriam Mercade, Gabrielle Potocki-Veronese
mSphere 5:26 p. (2020)10.1128/mSphere.00771-19
2019
Comparative genomic analyses reveal diverse virulence factors and antimicrobial resistance mechanisms in clinical Elizabethkingia meningoseptica strains
Jochen Blom, Nicolas Terrapon, Shicheng Chen, Marty Soehnlen, Jochen Blom Id, Bernard Henrissat, Edward D Walker
PLoS ONE 14:e0222648 (2019)10.1371/journal.pone.0222648
Interspecies Competition Impacts Targeted Manipulation of Human Gut Bacteria by Fiber-Derived Glycans
Michael Patnode, Zachary Beller, Nathan Han, Jiye Cheng, Samantha Peters, Nicolas Terrapon, Bernard Henrissat, Sophie Le Gall, Luc Saulnier, David Hayashi, Alexandra Meynier, Sophie Vinoy, Richard J Giannone, Robert L Hettich, Jeffrey I Gordon
Cell 179:59-73.e13 (2019)10.1016/j.cell.2019.08.011
Bacteroidetes use thousands of enzyme combinations to break down glycans
Pascal Lapébie, Vincent Lombard, Elodie Drula, Nicolas Terrapon, Bernard Henrissat
Nature Communications 10:1 (2019)10.1038/s41467-019-10068-5
Discovery of novel carbohydrate-active enzymes through the rational exploration of the protein sequences space
William Helbert, Laurent Poulet, Sophie Drouillard, Sophie Mathieu, Mélanie Loiodice, Marie Couturier, Vincent Lombard, Nicolas Terrapon, Jeremy Turchetto, Vincent Vincentelli, Bernard Henrissat
Proceedings of the National Academy of Sciences of the United States of America 116:6063-6068 (2019)10.1073/pnas.1815791116
A subfamily roadmap for functional glycogenomics of the evolutionarily diverse Glycoside Hydrolase Family 16 (GH16)
Alexander Holm Viborg, Nicolas Terrapon, Vincent Lombard, Gurvan Michel, Mirjam Czjzek, Bernard Henrissat, Harry Brumer
Journal of Biological Chemistry 294:15973-15986 (2019)10.1074/jbc.RA119.010619
2018
A surface endogalactanase in Bacteroides thetaiotaomicron confers keystone status for arabinogalactan degradation
Alan Cartmell, Li Muñoz-Muñoz, Jonathon Briggs, Didier Ndeh, Elisabeth Lowe, Arnaud Basle, Nicolas Terrapon, Katherine Stott, Tiaan Heunis, Joe Gray, Li Yu, Paul P. Dupree, Pearl Fernandes, Sayali Shah, Spencer Williams, Aurore Labourel, Matthias Trost, Bernard Henrissat, Harry Gilbert, Jose Munoz-Munoz
Nature Microbiology 3:1314-1326 (2018)10.1038/s41564-018-0258-8
Cultivation and sequencing of rumen microbiome members from the Hungate1000 Collection
Rekha Seshadri, Sinead Leahy, Graeme Attwood, Koon Hoong Teh, Suzanne Lambie, Adrian Cookson, Emiley Eloe-Fadrosh, Georgios Pavlopoulos, Michalis Hadjithomas, Neha Varghese, David Páez-Espino, Rechelle Perry, Gemma Henderson, Christopher J. Creevey, Nicolas Terrapon, Pascal Lapébie, Elodie Drula, Vincent Lombard, Edward M. Rubin, Nikos Kyrpides, Bernard Henrissat, Tanja Woyke, Natalia Ivanova, William Kelly, Nikola Palevich, Peter Janssen, Ron Ronimus, Samantha Noel, Priya Soni, Kerri Reilly, Todd Atherly, Cherie Ziemer, Andre-Denis Wright, Suzanne Ishaq, Michael Cotta, Stephanie Thompson, Katie Crosley, Nest Mckain, R John Wallace, Harry Flint, Jennifer Martin, Robert Forster, Robert Gruninger, Tim Mcallister, Rosalind Gilbert, Diane Ouwerkerk, Athol Klieve, Rafat Al Jassim, Stuart Denman, Chris Mcsweeney, Carly Rosewarne, Satoshi Koike, Yasuo Kobayashi, Makoto Mitsumori, Takumi Shinkai, Silvio Cravero, María Cerón Cucchi, Chris Creevey
Nature Biotechnology 36:359-367 (2018)10.1038/nbt.4110
Dietary pectic glycans are degraded by coordinated enzyme pathways in human colonic Bacteroides
Ana R Luis, Jonathon Briggs, Xiaoyang Zhang, Benjamin Farnell, Didier Ndeh, Aurore Labourel, Arnaud Basle, Alan Cartmell, Nicolas Terrapon, Katherine Stott, Elisabeth Lowe, Richard Mclean, Kaitlyn Shearer, Julia Schuckel, Immacolata Venditto, Marie-Christine Ralet, Bernard Henrissat, Eric Martens, Steven Mosimann, D Wade Abbott, Harry Gilbert, D. Wade Abbott
Nature Microbiology 3:210-219 (2018)10.1038/s41564-017-0079-1
PULDB: the expanded database of Polysaccharide Utilization Loci
Nicolas Terrapon, Vincent Lombard, Elodie Drula, Pascal Lapébie, Saad Al-Masaudi, Harry Gilbert, Bernard Henrissat
Nucleic Acids Research 46:D677-D683 (2018)10.1093/nar/gkx1022
2017
Ninety-nine de novo assembled genomes from the moose (Alces alces) rumen microbiome provide new insights into microbial plant biomass degradation
Olov Svartström, Johannes Alneberg, Nicolas Terrapon, Vincent Lombard, Ino de Bruijn, Jonas Malmsten, Ann-Marie Dalin, Emilie El Muller, Pranjul Shah, Paul Wilmes, Bernard Henrissat, Henrik Aspeborg, Anders Andersson
The International Society of Microbiologial Ecology Journal 11:2538-2551 (2017)10.1038/ismej.2017.108
A fibrolytic potential in the human ileum mucosal microbiota revealed by functional metagenomic
Orlane Patrascu, Fabienne Beguet-Crespel, Ludovica Marinelli, Emmanuelle Le Chatelier, Anne-Laure Abraham, Marion Leclerc, Christophe Klopp, Nicolas Terrapon, Bernard Henrissat, Hervé Blottiere, Joël Dore, Christel Maillet
Scientific Reports 7:np (2017)10.1038/srep40248
Unusual active site location and catalytic apparatus in a glycoside hydrolase family
Jose Munoz-Munoz, Alan Cartmell, Nicolas Terrapon, Bernard Henrissat, Harry J. Gilbert
Proceedings of the National Academy of Sciences of the United States of America 114:4936-4941 (2017)10.1073/pnas.1701130114
An evolutionarily distinct family of polysaccharide lyases removes rhamnose capping of complex arabinogalactan proteins
Jose Munoz-Munoz, Alan Cartmell, Nicolas Terrapon, Arnaud Basle, Bernard Henrissat, Harry J. Gilbert
Journal of Biological Chemistry 292:13271-13283 (2017)10.1074/jbc.M117.794578
Complex pectin metabolism by gut bacteria reveals novel catalytic functions
Didier Ndeh, Artur Rogowski, Alan Cartmell, Ana S. Luis, Arnaud Basle, Joseph Gray, Immacolata Venditto, Jonathon Briggs, Xiaoyang Zhang, Aurore Labourel, Nicolas Terrapon, Fanny Buffetto, Sergey Nepogodiev, Yao Xiao, Robert A. Field, Yanping Zhu, Malcolm A. O'Neill, Breeanna R. Urbanowicz, William S. York, Gideon J. Davies, D. Wade Abbott, Marie-Christine Ralet-Renard, Eric C. Martens, Bernard Henrissat, Harry J. Gilbert
Nature 544:65-+ (2017)10.1038/nature21725
A bioinformatics analysis of 3400 lytic polysaccharide oxidases from family AA9
Nicolas Lenfant, Matthieu Hainaut, Nicolas Terrapon, Elodie Drula, Vincent Lombard, Bernard Henrissat
Carbohydrate Research 448:166-174 (2017)10.1016/j.carres.2017.04.012
Comparative Metagenomics of Cellulose- and Poplar Hydrolysate-Degrading Microcosms from Gut Microflora of the Canadian Beaver (Castor canadensis) and North American Moose (Alces americanus) after Long-Term Enrichment
Mabel Wong, Weijun Wang, Marie Couturier, Fakhria Razeq, Vincent Lombard, Pascal Lapébie, Elizabeth Edwards, Nicolas Terrapon, Bernard Henrissat, Emma Master
Frontiers in Microbiology 8:2504 (2017)10.3389/fmicb.2017.02504
How members of the human gut microbiota overcome the sulfation problem posed by glycosaminoglycans
Alan Cartmell, Elisabeth Lowe, Arnaud Basle, Susan Firbank, Didier Ndeh, Heath Murray, Nicolas Terrapon, Vincent Lombard, Bernard Henrissat, Jeremy E Turnbull, Mirjam Czjzek, Harry Gilbert, David Bolam
Proceedings of the National Academy of Sciences of the United States of America 114:7037-7042 (2017)10.1073/pnas.1704367114
2016
A Dietary Fiber-Deprived Gut Microbiota Degrades the Colonic Mucus Barrier and Enhances Pathogen Susceptibility
Mahesh S. Desai, Anna M. Seekatz, Nicole M. Koropatkin, Nobuhiko Kamada, Christina A. Hickey, Mathis Wolter, Nicholas A. Pudlo, Sho Kitamoto, Nicolas Terrapon, Arnaud Muller, Vincent B. Young, Bernard Henrissat, Paul Wilmes, Thaddeus S. Stappenbeck, Gabriel Nunez, Eric C. Martens
Cell 167:1339-1353 (2016)10.1016/j.cell.2016.10.043
Unraveling the pectinolytic function of Bacteroides xylanisolvens using a RNA-seq approach and mutagenesis
Jordane Despres, Evelyne Forano, Pascale Lepercq, Sophie Comtet-Marre, Grégory Jubelin, Carl J. Yeoman, Margret E. Berg Miller, Christopher J. Fields, Nicolas Terrapon, Carine Le Bourvellec, Catherine M. G. C. Renard, Bernard Henrissat, Bryan A. White, Pascale Mosoni
BMC Genomics 27 (2016)10.1186/s12864-016-2758-3
Xylan degradation by the human gut Bacteroides xylanisolvens XB1A(T) involves two distinct gene clusters that are linked at the transcriptional level
Jordane Despres, Evelyne Forano, Pascale Lepercq, Sophie Comtet-Marre, Grégory Jubelin, Christophe Chambon, Carl J. Yeoman, Margaret E. Berg Miller, Christopher J. Fields, Eric Martens, Nicolas Terrapon, Bernard Henrissat, Bryan A. White, Pascale Mosoni
BMC Genomics 17 (2016)10.1186/s12864-016-2680-8
Unraveling the pectinolytic function of Bacteroides xylanisolvens using a RNA-seq approach and mutagenesis
Jordane Despres, Evelyne Forano, Pascale Lepercq, Sophie Comtet-Marre, Grégory Jubelin, Carl J. Yeoman, Margret E. Berg Miller, Christopher J. Fields, Nicolas Terrapon, Carine Le Bourvellec, Catherine M. G. C. Renard, Bernard Henrissat, Bryan A. White, Pascale Mosoni
BMC Genomics 17:147 (2016)10.1186/s12864-016-2472-1
2015
Genetic determinants of in vivo fitness and diet responsiveness in multiple human gut Bacteroides
Meng Wu, Nathan P. Mcnulty, Dmitry A. Rodionov, Matvei S. Khoroshkin, Nicholas W. Griffin, Jiye Cheng, Phil Latreille, Randall A. Kerstetter, Nicolas Terrapon, Bernard Henrissat, Andrei L. Osterman, Jeffrey I. Gordon
Science 350 (2015)10.1126/science.aac5992
Glycan complexity dictates microbial resource allocation in the large intestine
Artur Rogowski, Jonathon A. Briggs, Jennifer C. Mortimer, Theodora Tryfona, Nicolas Terrapon, Elisabeth C. Lowe, Arnaud Basle, Carl Morland, Alison M. Day, Hongjun Zheng, Theresa E. Rogers, Paul Thompson, Alastair R. Hawkins, Madhav P. Yadav, Bernard Henrissat, Eric C. Martens, Paul Dupree, Harry J. Gilbert, David N. Bolam
Nature Communications 6 (2015)10.1038/ncomms8481
Automatic prediction of polysaccharide utilization loci in Bacteroidetes species
Nicolas Terrapon, Vincent Lombard, Harry J. Gilbert, Bernard Henrissat
Bioinformatics 31:647-655 (2015)10.1093/bioinformatics/btu716
2014
Identification of divergent protein domains by combining HMM-HMM comparisons and co-occurrence detection
Amel Ghouila, Isabelle Florent, Fatma Zahra Guerfali, Nicolas Terrapon, Dhafer Laouini, Sadok Ben Yahia, Olivier Gascuel, Laurent Brehelin
PLoS ONE 9:e95275 (2014)10.1371/journal.pone.0095275
2012
Fitting hidden Markov models of protein domains to a target species: application to Plasmodium falciparum.
Nicolas Terrapon, Olivier Gascuel, Eric Marechal, Laurent Brehelin
BMC Bioinformatics 13:67 (2012)10.1186/1471-2105-13-67
2011
EuPathDomains: The Divergent Domain Database for Eukaryotic Pathogens
Amel Ghouila, Nicolas Terrapon, Olivier Gascuel, Fatma Guerfali, Dhafer Laouini, Eric Marechal, Laurent Brehelin
Infection, Genetics and Evolution 11:698-707 (2011)10.1016/j.meegid.2010.09.008
2009
Detection of new protein domains using co-occurrence: application to Plasmodium falciparum
Nicolas Terrapon, Olivier Gascuel, Eric Maréchal, Laurent Brehelin
Bioinformatics 25:3077-83 (2009)10.1093/bioinformatics/btp560
