Priscila Sutto-Ortiz
Research engineer
Research group: Viral Replicases: Structure, function and drug-design
Publications
2023
Biochemistry of the Respiratory Syncytial Virus L Protein Embedding RNA Polymerase and Capping Activities
Priscila Sutto-Ortiz, Jean-François Eléouët, François Ferron, Etienne Decroly
Viruses 15:341 (2023)10.3390/v15020341
2022
Potent Inhibition of SARS-CoV-2 nsp14 N 7-Methyltransferase by Sulfonamide-Based Bisubstrate Analogues
Rostom Ahmed-Belkacem, Marcel Hausdorff, Adrien Delpal, Priscila Sutto-Ortiz, Agathe M G Colmant, Franck Touret, Natacha S Ogando, Eric J Snijder, Bruno Canard, Bruno Coutard, Jean-Jacques Vasseur, Etienne Decroly, Françoise Debart
Journal of Medicinal Chemistry 65:6231-6249 (2022)10.1021/acs.jmedchem.2c00120
Distinctive Roles of Furin and TMPRSS2 in SARS-CoV-2 Infectivity
Rachid Essalmani, Jaspreet Jain, Delia Susan-Resiga, Ursula Andréo, Alexandra Evagelidis, Rabeb Mouna Derbali, David Huynh, Frédéric Dallaire, Mélanie Laporte, Adrien Delpal, Priscila Sutto-Ortiz, Bruno Coutard, Claudine Mapa, Keith Wilcoxen, Etienne Decroly, Tram Nq Pham, Éric Cohen, Nabil Seidah
Journal of Virology 96 (2022)10.1128/jvi.00128-22
2021
The methyltransferase domain of the Respiratory Syncytial Virus L protein catalyzes cap N7 and 2’-O-methylation
Priscila Sutto-Ortiz, Sergey Tcherniuk, Nina Ysebaert, Pravien Abeywickrema, Mathieu Noël, Alice Decombe, Françoise Debart, Jean-Jacques Vasseur, Bruno Canard, Dirk Roymans, Peter Rigaux, Jean-François Eléouët, Etienne Decroly
PLoS Pathogens 17:e1009562 (2021)10.1371/journal.ppat.1009562
The methyltransferase domain of the Respiratory Syncytial Virus L protein catalyzes cap N7 and 2’-O-methylation
Priscila Sutto-Ortiz, Sergey Tcherniuk, Nina Ysebaert, Pravien Abeywickrema, Mathieu Noël, Alice Decombe, Françoise Debart, Jean-Jacques Vasseur, Bruno Canard, Dirk Roymans, Peter Rigaux, Jean-François Eléouët, Etienne Decroly
PLoS Pathogens 17:1-20 (2021)10.1371/journal.ppat.1009562
2020
Synthesis of adenine dinucleosides SAM analogs as specific inhibitors of SARS-CoV nsp14 RNA cap guanine-N7-methyltransferase
Rostom Ahmed-Belkacem, Priscila Sutto-Ortiz, Mathis Guiraud, Bruno Canard, Jean-Jacques Vasseur, Etienne Decroly, Françoise Debart
European Journal of Medicinal Chemistry 201:112557 (2020)10.1016/j.ejmech.2020.112557
2019
Structure of the Respiratory Syncytial Virus Polymerase Complex
Morgan S A Gilman, Cheng Liu, Amy Fung, Ishani Behera, Paul Jordan, Peter Rigaux, Nina Ysebaert, Sergey Tcherniuk, Julien Sourimant, Jean-Francois Eleouet, Priscila Sutto-Ortiz, Etienne Decroly, Dirk Roymans, Zhinan Jin, Jason S Mclellan
Cell 179:193-204.e14 (2019)10.1016/j.cell.2019.08.014
Synthesis of Adenine Dinucleosides 2′,5′-Bridged by Sulfur-Containing Linkers as Bisubstrate SAM Analogues for Viral RNA 2′- O -Methyltransferases
Rostom Ahmed-Belkacem, Priscila Sutto Ortiz, Etienne Decroly, Jean-Jacques Vasseur, Françoise Debart
European Journal of Organic Chemistry 2019 (2019)10.1002/ejoc.201901120
2018
Galactolipase activity of Talaromyces thermophilus lipase on galactolipid micelles, monomolecular films and UV-absorbing surface-coated substrate
Inès Belhaj, Sawsan Amara, Goetz Parsiegla, Priscila Sutto-Ortiz, Moulay Sahaka, Hafedh Belghith, Audric Rousset, Dominique Lafont, Frédéric Carriere
Biochimica et Biophysica Acta Molecular and Cell Biology of Lipids 1863:1006-1015 (2018)10.1016/j.bbalip.2018.05.016
IR spectroscopy analysis of pancreatic lipase-related protein 2 interaction with phospholipids: 2. Discriminative recognition of various micellar systems and characterization of PLRP2-DPPC-bile salt complexes
Eduardo Mateos-Diaz, Priscila Sutto-Ortiz, Moulay Sahaka, Deborah Byrne, Hélène Gaussier, Frédéric Carrière
Chemistry and Physics of Lipids 211:66-76 (2018)10.1016/j.chemphyslip.2017.11.012
IR spectroscopy analysis of pancreatic lipase-related protein 2 interaction with phospholipids: 3. Monitoring DPPC lipolysis in mixed micelles
Eduardo Mateos-Diaz, Priscila Sutto-Ortiz, Moulay Sahaka, Jorge Rodriguez, Frédéric Carrière
Chemistry and Physics of Lipids 211:77-85 (2018)10.1016/j.chemphyslip.2017.11.009
