Véronique Zamboni
Engineer
Research group: Structural Glycobiology and Neurobiology
Service : Crystallogenesis and crystallography
Correspondent Preparations in biology
Publications
2023
Fluorescence polarisation activity-based protein profiling for the identification of deoxynojirimycin-type inhibitors selective for lysosomal retaining alpha- and beta-glucosidases
Daniël van der Gracht, Rhianna J Rowland, Véronique Roig-Zamboni, Maria J Ferraz, Max Louwerse, Paul P Geurink, Johannes M F G Aerts, Gerlind Sulzenbacher, Gideon J Davies, Herman S Overkleeft, Marta Artola
Chemical Science 14:9136-9144 (2023)10.1039/d3sc01021j
2022
Direct capture, inhibition and crystal structure of HsaD (Rv3569c) from M. tuberculosis
Sarah Barelier, Romain Avellan, Giri Raj Gnawali, Patrick Fourquet, Véronique Roig-Zamboni, Isabelle Poncin, Vanessa Point, Yves Bourne, Stéphane Audebert, Luc Camoin, Christopher Spilling, Stéphane Canaan, Jean‐françois Cavalier, Gerlind Sulzenbacher
FEBS Journal (2022)10.1111/febs.16645
1,6- epi -Cyclophellitol Cyclosulfamidate Is a Bona Fide Lysosomal α-Glucosidase Stabilizer for the Treatment of Pompe Disease
Ken Kok, Chi-Lin Kuo, Rebecca Katzy, Lindsey Lelieveld, Liang Wu, Véronique Roig-Zamboni, Gijsbert van der Marel, Jeroen Codée, Gerlind Sulzenbacher, Gideon Davies, Herman Overkleeft, Johannes Aerts, Marta Artola
Journal of the American Chemical Society 144:14819-14827 (2022)10.1021/jacs.2c05666
Molecular basis for substrate recognition and septum cleavage by AtlA, the major N-acetylglucosaminidase of Enterococcus faecalis
Véronique Roig-Zamboni, Sarah Barelier, Robert Dixon, Nicola Galley, Amani Ghanem, Quoc Phong Nguyen, Héloize Cahuzac, Bartłomiej Salamaga, Peter Davis, Yves Bourne, Stéphane Mesnage, Florence Vincent
Journal of Biological Chemistry 298:101915 (2022)10.1016/j.jbc.2022.101915
2021
First insights into the structural features of Ebola virus methyltransferase activities
Coralie Valle, Baptiste Martin, François Ferron, Véronique Roig-Zamboni, Aline Desmyter, Françoise Debart, Jean Jacques Vasseur, Bruno Canard, Bruno Coutard, Etienne Decroly
Nucleic Acids Research 49:1737-1748 (2021)10.1093/nar/gkaa1276
Carnitine is a pharmacological allosteric chaperone of the human lysosomal α -glucosidase
Roberta Iacono, Nadia Minopoli, Maria Carmina Ferrara, Antonietta Tarallo, Carla Damiano, Caterina Porto, Sandra Strollo, Véronique Roig-Zamboni, Gianfranco Peluso, Gerlind Sulzenbacher, Beatrice Cobucci-Ponzano, Giancarlo Parenti, Marco Moracci
Journal of Enzyme Inhibition and Medicinal Chemistry 36:2068-2079 (2021)10.1080/14756366.2021.1975694
2019
Substrate binding mode and catalytic mechanism of human heparan sulfate d-glucuronyl C5 epimerase
Claire Debarnot, Yoan Monneau, Veronique Roig-Zamboni, Vincent Delauzun, Christine Le Narvor, Emeline Richard, Jérôme Hénault, Adeline Goulet, Firas Fadel, Romain R Vivès, Bernard Priem, David Bonnaffé, Hugues Lortat-Jacob, Yves Bourne
Proceedings of the National Academy of Sciences of the United States of America 116:6760-6765 (2019)10.1073/pnas.1818333116
2018
Genetic and enzymatic characterization of 3-O-sulfotransferase SNPs associated with Plasmodium falciparum parasitaemia
Ngoc Thy Nguyen, Romain R Vivès, Magali Iché-Torres, Vincent Delauzun, Els Saesen, Veronique Roig-Zamboni, Hugues Lortat-Jacob, Pascal Rihet, Yves Bourne
Glycobiology 28:534-541 (2018)10.1093/glycob/cwy038
Glycosylate and move! The glycosyltransferase Maf is involved in bacterial flagella formation
Gerlind Sulzenbacher, Veronique Roig-Zamboni, Régine Lebrun, Yann Guérardel, Dorothée Murat, Pascal Mansuelle, Nao Yamakawa, Xin-Xin Qian, Renaud Vincentelli, Yves Bourne, Long-Fei Wu, François Alberto
Environmental Microbiology 20:228-240 (2018)10.1111/1462-2920.13975
2017
Structure of human lysosomal acid α-glucosidase-a guide for the treatment of Pompe disease
Véronique Roig-Zamboni, Beatrice Cobucci-Ponzano, Roberta Iacono, Maria Carmina Ferrara, Stanley Germany, Yves Bourne, Giancarlo Parenti, Marco Moracci, Gerlind Sulzenbacher
Nature Communications (2017)10.1038/s41467-017-01263-3
Structure of human lysosomal acid α-glucosidase–a guide for the treatment of Pompe disease
Veronique Roig-Zamboni, Beatrice Cobucci-Ponzano, Roberta Iacono, Maria Carmina Ferrara, Stanley Germany, Yves Bourne, Giancarlo Parenti, Marco Moracci, Gerlind Sulzenbacher
Nature Communications 8:1111 (2017)10.1038/s41467-017-01263-3
Structural insights into a family 39 glycoside hydrolase from the gut symbiont Bacteroides cellulosilyticus WH2
Ahmad Ali-Ahmad, Marie-Line Garron, Véronique Roig-Zamboni, Nicolas Lenfant, Didier Nurizzo, Bernard Henrissat, Jean-Guy Berrin, Yves Bourne, Florence Vincent
Journal of Structural Biology 197:227-235 (2017)10.1016/j.jsb.2016.11.004
2015
Structural basis for carbohydrate binding properties of a plant chitinase-like agglutinin with conserved catalytic machinery
Gerlind Sulzenbacher, Veronique Roig-Zamboni, Willy J. Peumans, Bernard Henrissat, Els J. M. Van Damme, Yves Bourne
Journal of Structural Biology 190:115-121 (2015)10.1016/j.jsb.2015.01.013
2010
Crystal Structure of the GalNAc/Gal-Specific Agglutinin from the Phytopathogenic Ascomycete Sclerotinia sclerotiorum Reveals Novel Adaptation of a β-Trefoil Domain
Gerlind Sulzenbacher, Véronique Roig-Zamboni, Willy J Peumans, Pierre Rougé, Els J M van Damme, Yves Bourne
Journal of Molecular Biology 400:715-723 (2010)10.1016/j.jmb.2010.05.038
2006
LppX is a lipoprotein required for the translocation of phthiocerol dimycocerosates to the surface of Mycobacterium tuberculosis
Gerlind Sulzenbacher, Stéphane Canaan, Yann Bordat, Olivier Neyrolles, Gustavo Stadthagen, Véronique Roig-Zamboni, Jean Rauzier, Damien Maurin, Françoise Laval, Mamadou Daffé, Christian Cambillau, Brigitte Gicquel, Yves Bourne, Mary Jackson
EMBO Journal (2006)10.1038/sj.emboj.7601048
2005
Crystal structure of the conserved hypothetical protein Rv1155 from Mycobacterium tuberculosis
Stéphane Canaan, Gerlind Sulzenbacher, Véronique Roig-Zamboni, Loréna Scappuccini-Calvo, Frédéric Frassinetti, Damien Maurin, Christian Cambillau, Yves Bourne, Christian Griesinger
FEBS Letters (2005)10.1016/j.febslet.2004.11.069
2004
Structure of Escherichia coli YhdH, a putative quinone oxidoreductase
Gerlind Sulzenbacher, Véronique Roig-Zamboni, Fabienne Pagot, Sacha Grisel, Aurelia Salomoni, Christel Valencia, Valérie Campanacci, Renaud Vincentelli, Mariella Tegoni, Hans Eklund, Christian Cambillau
Acta crystallographica Section D : Structural biology [1993-...] (2004)10.1107/S0907444904020220
Crystal Structure of E. coli YddE Protein Reveals a Striking Homology With Diaminopimelate Epimerase
Alice Grassick, Gerlind Sulzenbacher, Véronique Roig-Zamboni, Valérie Campanacci, Christian Cambillau, Yves Bourne
Proteins - Structure, Function and Bioinformatics 55:764-767 (2004)10.1002/prot.20025
2002
A medium-throughput crystallization approach
Gerlind Sulzenbacher, Arnaud Gruez, Véronique Roig-Zamboni, Silvia Spinelli, Christel Valencia, Fabienne Pagot, Renaud Vincentelli, Christophe Bignon, Aurelia Salomoni, Sacha Grisel, Damien Maurin, Céline Huyghe, Kent Johansson, Alice Grassick, Alain Roussel, Yves Bourne, Sophie Perrier, Linda Miallau, Phillippe Cantau, Eric Blanc, Michel Genevois, Alain Grossi, André Zenatti, Valérie Campanacci, Christian Cambillau
Acta crystallographica Section D : Structural biology [1993-...] 58:2109-2115 (2002)10.1107/s0907444902013938
