Our laboratory

The Architecture et Fonction des Macromolécules Biologiques (AFMB) laboratory, overseen by the CNRS and AMU, is a center of structural biology localized on the Luminy campus in the South of Marseilles, France, and in partnership with INRAE under contract. The aim of our researches is to depict the architecture of proteins or macromolecular assemblies at the molecular level to understand the biological mechanisms which they govern. The description of interactions between macromolecules or a macromolecule and a ligand is also crucial to manipulate these complex molecules. Finally, to understand the molecular diversity of members of some protein families, we also analyze the big data issued from large-scale genome sequencing centers.

  • Monday 27th of September at 3pm: Alba Grifoni, Center for Infectious Disease and Vaccine Research, La Jolla Institute for Immunology, CA, USA, "T cell immunity and how it works in viral infection : Lesson learned from SARS-CoV-2"
    The AFMB seminars are currently webinars. If you are interested in joining one or more webinars please send an email to afmb-seminar(at) to request the connection link.

    Abstract (...)

    T cells are remarkably complex and multifaceted; this allows them to adapt to different viral threats and mediate effective responses. In my talk, I will discuss their general role in the viral immune response and, in particular, in SARS-CoV-2 infection investigating their behavior in the different clinical forms of COVID-19 diseases or after vaccination. I will also address their durability and their resilience in cross-recognizing the upcoming SARS-CoV-2 variants or other members of the Coronavirus family
    All seminars.
  • Bhawna Sama awarded the gold medal by the ’Fondation Méditerranée Infection’ for her work on large genome RNA viruses
  • Covid-19: why the lab leak theory must be formally investigated
    By Virginie Courtier and Etienne Decroly (see)
  • Bernard Henrissat receives the Bruce A. Stone Award for his excellence in Plant Polysaccharide Biochemistry.
  • Bruno Canard and Etienne Decroly interviewed by the CNRS about the COVID19 pandemic.
  • The work of Rhian Jones, Juan Reguera and collaborators on viral replication spotlighted by the CNRS-INSB, the INSERM, and the ESRF.
  • The work of Bruno Canard and Etienne Decroly on SARS-CoV-2 presented in a video by the CNRS.
  • Isabelle Imbert nominated to the rank of “Knight in the National Order of the Legion of Honour”.
Events Positions Available

AFMB - UMR7257 CNRS - Aix-Marseille Univ. - Case 932
163 Avenue de Luminy 13288 Marseille CEDEX 09 FRANCE

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