Accueil du site > staff > Bruno CANARD


Directeur de recherche

AFMB Polytech Case 925
Campus de Luminy
163 Avenue de Luminy
13288 Marseille CEDEX 09
Fax : 04 91 82 86 38

Tel: 04 91 82 86 46

Réplicases Virales : Structure, Mécanisme et Drug-Design


Curriculum vitae

Bruno Canard obtained a PhD in 1991 in Microbiology and Biochemistry from the Université of Paris VII at the Institut Pasteur (mentor: Dr. Stewart T. Cole), Paris, and post-doctoral training in 1995-1998 at Harvard Medical School, Dept. Biological Chemistry and Molecular Pharmacology (mentor: Dr. Charles C. Richardson), Boston. He is currently principal investigator of the team "Viral Replication: Structure, Mechanisms, and Drug Design" at the Architecture and Functions of Biological Macromolecules Laboratory, Aix-Marseille Université, Marseille, France, where he holds a CNRS position as Directeur de Recherche. His current interests are the structure and function of enzymes involved in viral replication and RNA capping, and their use in antiviral drug design.

Dernières Publications

  1. Synthesis of Adenine Dinucleosides SAM Analogs as Specific Inhibitors of SARS-CoV nsp14 RNA Cap guanine-N7-methyltransferase (2020)
    Ahmed-Belkacem R, Sutto-Ortiz P, Guiraud M, Canard B , Vasseur JJ, Decroly E, Debart F.
    Eur J Med Chem Jun 12;201 112557
  2. Favipiravir strikes the SARS-CoV-2 at its Achilles heel, the RNA polymerase. (2020)
    Shannon A, Selisko B, Le N, Huchting J, Touret F, Piorkowski G, Fattorini V, Ferron F, Decroly E, Meier C, Coutard B, Peersen O, Canard B .
    bioRxiv. May 15
  3. Drugs against SARS-CoV-2: what do we know about their mode of action? (2020)
    Valle C, Martin B, Touret F, Shannon A, Canard B ., Guillemot JC, Coutard B Decroly E.
    Rev Med Virol in press
  4. Valle C, Martin B, Debart F, Vasseur JJ, Imbert I, Canard B , Coutard B, Decroly E
    J Virol in press
  5. Shannon A, Tuyet Le NT, Selisko B, Eydoux C, Alvarez K, Guillemot JC, Decroly E, Peersen O, Ferron F, Canard B
    Antiviral Res in press 104793

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