Candidates, at an early-career stage and of any nationality, are invited to apply to this offer to develop competitive, independent research emphasizing cryo-EM projects or integrative structural biology projects. They should meet the criteria required for successful application to national and international funding such as ATIP-Avenir, FRM, ANR “Jeunes chercheurs – Jeunes chercheuses” (JCJC), ERC-StG or CoG, A*Midex chairs of excellence or any equivalent installation grant. Senior researchers already holding a permanent position are also welcome to apply.

The Architecture and Function of Biological Macromolecules (AFMB) laboratory (, supervised by the CNRS and Aix-Marseille Univ (AMU) and in partnership with INRAE, is internationally recognized in the field of structural biology. This laboratory gathers an average number of 75 permanent and non-permanent staff members contributing to 6 research teams and to several administrative and technological facilities. It is located in the Luminy campus in the south of Marseille, where it benefits from an exceptional scientific, technological and educational environment.

Research themes at the AFMB laboratory range from glycobiology and glycogenomics to microbiology, virology and neurobiology. The common objective is the detailed description of the structure-function relationships of proteins, protein-ligand complexes and macromolecular assemblies using modern multidisciplinary approaches in bioinformatics, genetic engineering, biology/biochemistry, biophysics, medicinal chemistry and structural biology.

Our research is based on a unique network bringing together efficient integrated technological facilities in bioinformatics, structural biology and screening of bioactive molecules. These facilities hold the GIS-IbiSA and Aix-Marseille labels and are partners of the national infrastructures FRISBI and ChemBioFrance, and they make up valuable learning and training means (e.g. EMBO Practical Courses 2011, 2015 and 2022). By early 2023, the structural biology facility will offer access to the last generation 200 kV cryo-EM equipment in the frame of a regional project. The AFMB laboratory is also a member of the local IM2B institute, which federates a network of 10 laboratories/institutes aimed at strengthening interdisciplinary research and teaching in microbiology and its applications in bioenergy, environment and health.

Starting package: The selected candidate will be provided with office and lab spaces for up to 5 people, contribution to bench fees, and facilitated access to all on-site technological facilities. The early-stage researcher will be coached to apply to a tenured position at the CNRS.

Applicants are invited to send a CV, a summary of their past and present research activities and of their project, and a detailed motivation letter to Yves Bourne (yves.bourne at The preselected candidates will be invited to orally present and defend their project in front of the executive committee.

Position open as long as this advert is posted.

Publié le février 10, 2022