Denis Ptchelkine
Research engineer
Service : Transmission electron microscopy
Publications
2022
Molecular Determinants of Fibrillation in a Viral Amyloidogenic Domain from Combined Biochemical and Biophysical Studies
Juliet F Nilsson, Hakima Baroudi, Frank Gondelaud, Giulia Pesce, Christophe Bignon, Denis Ptchelkine, Joseph Chamieh, Hervé Cottet, Andrey V Kajava, Sonia Longhi
International Journal of Molecular Sciences 24:399 (2022)10.3390/ijms24010399
Functional benefit of structural disorder for the replication of measles, Nipah and Hendra viruses
Frank Gondelaud, Giulia Pesce, Juliet F. Nilsson, Christophe Bignon, Denis Ptchelkine, Denis Gerlier, Cyrille Mathieu, Sonia Longhi
Essays in Biochemistry (2022)10.1042/EBC20220045
Experimental Evidence of Intrinsic Disorder and Amyloid Formation by the Henipavirus W Proteins
Giulia Pesce, Frank Gondelaud, Denis Ptchelkine, Juliet F Nilsson, Christophe Bignon, Jérémy Cartalas, Patrick Fourquet, Sonia Longhi
International Journal of Molecular Sciences 23:923 (2022)10.3390/ijms23020923
2019
Optimised oligonucleotide substrates to assay XPF-ERCC1 nuclease activity for the discovery of DNA repair inhibitors
Adam M Thomas, Sanja Brolih, Joanna F Mcgouran, Afaf H El-Sagheer, Denis Ptchelkine, Morgan Jones, Neil Q Mcdonald, Peter J Mchugh, Tom Brown
Chemical Communications 55:11671-11674 (2019)10.1039/c9cc05476f
2017
X-ray crystallography and NMR show that 5-formylcytosine does not change the global structure of DNA
Jack S Hardwick, Denis Ptchelkine, Afaf H El-Sagheer, Ian Tear, Daniel Singleton, Simon E V Phillips, Andrew N Lane, Tom Brown
Nature Structural and Molecular Biology 24:544-552 (2017)10.1038/nsmb.3411
Intracellular immunization against HIV infection with an intracellular antibody that mimics HIV integrase binding to the cellular LEDGF protein
Leyuan Bao, Clare Hannon, Abimael Cruz-Mignoni, Denis Ptchelkine, Mei-Yi Sun, Ami Miller, Wilawan Bunjobpol, Camilo E Quevedo, Mariliza Derveni, Jennifer Chambers, Alison Simmons, Simon E V Phillips, Terence H Rabbitts
Scientific Reports 7 (2017)10.1038/s41598-017-16742-2
Unique architecture of thermophilic archaeal virus APBV1 and its genome packaging
Denis Ptchelkine, Ashley Gillum, Tomohiro Mochizuki, Soizick Lucas-Staat, Ying Liu, Mart Krupovic, Simon Phillips, David Prangishvili, Juha Huiskonen
Nature Communications 8:1436 (2017)10.1038/s41467-017-01668-0
2012
Structural Framework for Covalent Inhibition of Clostridium botulinum Neurotoxin A by Targeting Cys165.
Enrico A Stura, Laura Le Roux, Karine Guitot, Sandra Garcia, Sarah Bregant, Fabrice Beau, Laura Vera, Guillaume Collet, Denis Ptchelkine, Huseyin Bakirci, Vincent Dive
Journal of Biological Chemistry 287:33607-14 (2012)10.1074/jbc.M112.396697
2010
Structural Basis of TBX5–DNA Recognition: The T-Box Domain in Its DNA-Bound and -Unbound Form
Christian Stirnimann, Denis Ptchelkine, Clemens Grimm, Christoph Müller
Journal of Molecular Biology 400:71-81 (2010)10.1016/j.jmb.2010.04.052
2008
Structural basis for LEAFY floral switch function and similarity with helix-turn-helix proteins.
Cécile Hamès, Denis Ptchelkine, Clemens Grimm, Emmanuel Thevenon, Edwige Moyroud, Francine Gérard, Jean-Louis Martiel, Reyes Benlloch, François Parcy, Christoph W Müller
EMBO Journal 27:2628-37 (2008)10.1038/emboj.2008.184
