Sonia LONGHI

Sonia LONGHI is Director of Research at the Center for the National Scientific Research (CNRS). She is the head of the "Structural Disorder and Molecular Recognition" group within the AFMB laboratory, Marseille. She obtained a PhD in molecular biology from the Universitá degli Studi of Milan in 1993. She got a HDR in structural virology from the University of Aix-Marseille I in 2003. Her scientific focus is on intrinsically disordered proteins (IDPs) and the mechanistic and functional aspects of the interactions they establish with partners. To date, she has authored 103 scientific publications and edited a book on measles virus nucleoprotein. She also co-edited (with Prof. Vladimir Uversky) a book on the experimental approaches to characterize IDPs and a book on structural disorder within viral proteins(Wiley).

Interview on "flexible viruses"

Latest Publications

1. Folding Mechanism of the SH3 Domain from Grb2. (2018)
   Troilo F, Bonetti D, Camilloni C, Toto A, Longhi S , Brunori M, Gianni S
   J Phys Chem B in press
2. Conformational response to charge clustering in synthetic intrinsically disordered proteins. (2018)
   Tedeschi G, Salladini E, Santambrogio C, Grandori R, Longhi S , Brocca S
   Biochim Biophys Acta 1862 2204-2214
3. How Robust Is the Mechanism of Folding-Upon-Binding for an Intrinsically Disordered Protein? (2018)
   Bonetti D, Troilo F, Brunori M, Longhi S , Gianni S
   Biophys J 114 1889-1894
4. Exploration of nucleoprotein alpha-MoRE and XD interactions of Nipah and Hendra viruses. (2018)
   Shang X, Chu W, Chu X, Xu L, Longhi S , Wang J
   J Mol Model 24 113
5. InSiDDe: A Server for Designing Artificial Disordered Proteins. (2017)
   Schramm A, Lieutaud P, Gianni S, Longhi S , Bignon C
   Int J Mol Sci 19
6. Structural disorder and induced folding within two cereal, ABA stress and ripening (ASR) proteins. (2017)
   Hamdi K, Salladini E, O'Brien DP, Brier S, Chenal A, Yacoubi I, Longhi S
   Sci Rep 7 15544
7. Interfacial properties of NTAIL, an intrinsically disordered protein. (2017)
   Benarouche A, Habchi J, Cagna A, Maniti O, Girard-Egrot A, Cavalier JF, Longhi S , Carriere F
   Biophys J 113 2723-2735
8. Partner-mediated polymorphism of an intrinsically disordered protein. (2017)
   Bignon C, Troilo F, Gianni S, Longhi S
   J Mol Biol 430 2493-2507
9. [How is transcription reinitiation governed in measles virus?] (2017)
   Bloyet LM, Roche P, Gerlier D, Longhi S
   Med Sci (Paris) 33 843-845
10. The Henipavirus V protein is a prevalently unfolded protein with a zinc-finger domain involved in binding to DDB1. (2017)
    Salladini E, Delauzun V and Longhi S
    Mol Biosyst 13 2254-2267