The electron microscopy service permits the structural characterization of biological systems and large macromolecular assemblies, as a complementary approach to x-ray crystallography.
The service allows users to perform all steps for the preparation of biological samples by negative staining to enable high contrast imaging form naturally low-contrast objects, imaging acquisition on the embedded camera and image analysis. This approach can be used to characterize the structural homogeneity of a protein sample, generate a low resolution 3D structure or identify large conformational changes in proteins or complexes upon addition of ligands.
Academia and industries
To be defined from the service requested