Gut microbiome of the largest living rodent harbors unprecedented enzymatic systems to degrade plant polysaccharides

Lucelia Cabral, Gabriela Persinoti, Douglas Paixão, Marcele Martins, Mariana Morais, Mariana Chinaglia, Mariane Domingues, Mauricio Sforca, Renan Pirolla, Wesley Generoso, Clelton Santos, Lucas Maciel, Nicolas Terrapon, Vincent Lombard, Bernard Henrissat, Mario Murakami

Nature Communications 13:629 (2022)10.1038/s41467-022-28310-y

Exploring the impact of Verticillium wilt disease on the mechanical properties of elementary flax (Linum usitatissimum L.) fibres

Lucile Nuez, Sylvie Durand, Alessia Melelli, Jean-Guy Berrin, Mireille Haon, Elodie Drula, Johnny Beaugrand, Pierre D’arras, Alain Bourmaud, Christophe Baley

Industrial Crops and Products 182:114900 (2022)10.1016/j.indcrop.2022.114900

The Land–Sea Connection: Insights Into the Plant Lineage from a Green Algal Perspective

Charles Bachy, Fabian Wittmers, Jan Muschiol, Maria Hamilton, Bernard Henrissat, Alexandra Worden

Annual Review of Plant Biology 73 (2022)10.1146/annurev-arplant-071921-100530

Functional exploration of the glycoside hydrolase family GH113

Marie Couturier, Mélanie Touvrey-Loiodice, Nicolas Terrapon, Elodie Drula, Laurine Buon, Christine Chirat, Bernard Henrissat, William Helbert

PLoS ONE 17:e0267509 (2022)10.1371/journal.pone.0267509

Molecular basis for substrate recognition and septum cleavage by AtlA, the major N-acetylglucosaminidase of Enterococcus faecalis

Véronique Roig-Zamboni, Sarah Barelier, Robert Dixon, Nicola Galley, Amani Ghanem, Quoc Phong Nguyen, Héloize Cahuzac, Bartłomiej Salamaga, Peter Davis, Yves Bourne, Stéphane Mesnage, Florence Vincent

Journal of Biological Chemistry 101915 (2022)10.1016/j.jbc.2022.101915

Distribution of Charged Residues Affects the Average Size and Shape of Intrinsically Disordered Proteins

Greta Bianchi, Marco Mangiagalli, Alberto Barbiroli, Sonia Longhi, Rita Grandori, Carlo Santambrogio, Stefania Brocca

Biomolecules 12:561 (2022)10.3390/biom12040561

Mechanistic insights into consumption of the food additive xanthan gum by the human gut microbiota

Matthew Ostrowski, Sabina Leanti La Rosa, Benoit Kunath, Andrew Robertson, Gabriel Pereira, Live Hagen, Neha Varghese, Ling Qiu, Tianming Yao, Gabrielle Flint, James Li, Sean Mcdonald, Duna Buttner, Nicholas Pudlo, Matthew Schnizlein, Vincent Young, Harry Brumer, Thomas Schmidt, Nicolas Terrapon, Vincent Lombard, Bernard Henrissat, Bruce Hamaker, Emiley Eloe-Fadrosh, Ashootosh Tripathi, Phillip Pope, Eric Martens

Nature Microbiology 7:556-569 (2022)10.1038/s41564-022-01093-0

Evolutionary transition to the ectomycorrhizal habit in the genomes of a hyperdiverse lineage of mushroom‐forming fungi

Brian Looney, Shingo Miyauchi, Emmanuelle Morin, Elodie Drula, Pierre Emmanuel Courty, Annegret Kohler, Alan Kuo, Kurt Labutti, Jasmyn Pangilinan, Anna Lipzen, Robert Riley, William Andreopoulos, Guifen He, Jenifer Johnson, Matt Nolan, Andrew Tritt, Kerrie Barry, Igor Grigoriev, László Nagy, David Hibbett, Bernard Henrissat, P. Brandon Matheny, Jesse Labbé, Francis Martin

New Phytologist 233:2294-2309 (2022)10.1111/nph.17892

Phylogenomics and Comparative Genomics Highlight Specific Genetic Features in Ganoderma Species

Yi-Fei Sun, Annie Lebreton, Jia-Hui Xing, Yu-Xuan Fang, Jing Si, Emmanuelle Morin, Shingo Miyauchi, Elodie Drula, Steven Ahrendt, Kelly Cobaugh, Anna Lipzen, Maxim Koriabine, Robert Riley, Annegret Kohler, Kerrie Barry, Bernard Henrissat, Igor Grigoriev, Francis Martin, Bao-Kai Cui

Journal of Fungi 8:311 (2022)10.3390/jof8030311

Assembly and synthesis of the extracellular matrix in brown algae

Lisa Mazéas, Rina Yonamine, Tristan Barbeyron, Bernard Henrissat, Elodie Drula, Nicolas Terrapon, Chikako Nagasato, Cécile Hervé

Seminars in Cell and Developmental Biology (2022)10.1016/j.semcdb.2022.03.005

Phenotypic and Genomic Diversification in Complex Carbohydrate-Degrading Human Gut Bacteria

Nicholas Pudlo, Karthik Urs, Ryan Crawford, Ali Pirani, Todd Atherly, Roberto Jimenez, Nicolas Terrapon, Bernard Henrissat, Daniel Peterson, Cherie Ziemer, Evan Snitkin, Eric Martens

mSystems 7:e0094721 (2022)10.1128/msystems.00947-21

A dual mechanism of action of AT-527 against SARS-CoV-2 polymerase

Ashleigh Shannon, Véronique Fattorini, Bhawna Sama, Barbara Selisko, Mikael Feracci, Camille Falcou, Pierre Gauffre, Priscila El Kazzi, Adrien Delpal, Etienne Decroly, Karine Alvarez, Cécilia Eydoux, Jean-Claude Guillemot, Adel Moussa, Steven Good, Paolo La Colla, Kai Lin, Jean-Pierre Sommadossi, Yingxiao Zhu, Xiaodong Yan, Hui Shi, Francois Ferron, Bruno Canard

Nature Communications 13 (2022)10.1038/s41467-022-28113-1

Structural and functional analyses of the Porphyromonas gingivalis type IX secretion system PorN protein

Olivier Fuchsbauer, Ignacio Lunar Silva, Eric Cascales, Alain Roussel, Philippe Leone

Journal of Biological Chemistry 298 (2022)10.1016/j.jbc.2022.101618

Experimental Evidence of Intrinsic Disorder and Amyloid Formation by the Henipavirus W Proteins

Giulia Pesce, Frank Gondelaud, Denis Ptchelkine, Juliet Nilsson, Christophe Bignon, Jérémy Cartalas, Patrick Fourquet, Sonia Longhi

International Journal of Molecular Sciences 23:923 (2022)10.3390/ijms23020923

The carbohydrate-active enzyme database: functions and literature

Elodie Drula, Marie-Line Garron, Suzan Dogan, Vincent Lombard, Bernard Henrissat, Nicolas Terrapon

Nucleic Acids Research 50:D571-D577 (2022)10.1093/nar/gkab1045

Fluoxetine targets an allosteric site in the enterovirus 2C AAA+ ATPase and stabilizes a ring-shaped hexameric complex

Daniel Hurdiss, Priscila El Kazzi, Lisa Bauer, Nicolas Papageorgiou, Francois Ferron, Tim Donselaar, Arno L.W. van Vliet, Tatiana Shamorkina, Joost Snijder, Bruno Canard, Etienne Decroly, Andrea Brancale, Tzviya Zeev-Ben-Mordehai, Friedrich Förster, Frank J.M. van Kuppeveld, Bruno Coutard

Science Advances 8 (2022)10.1126/sciadv.abj7615

Synthesis, Structure–Activity Relationships, and Antiviral Profiling of 1-Heteroaryl-2-Alkoxyphenyl Analogs As Inhibitors of SARS-CoV-2 Replication

Dorothée Bardiot, Laura Vangeel, Mohamed Koukni, Philippe Arzel, Marleen Zwaagstra, Heyrhyoung Lyoo, Patrick Wanningen, Shamshad Ahmad, Linlin Zhang, Xinyuanyuan Sun, Adrien Delpal, Cecilia Eydoux, Jean-Claude Guillemot, Eveline Lescrinier, Hugo Klaassen, Pieter Leyssen, Dirk Jochmans, Karolien Castermans, Rolf Hilgenfeld, Colin Robinson, Etienne Decroly, Bruno Canard, Eric Snijder, Martijn Hemert, Frank van Kuppeveld, Patrick Chaltin, Johan Neyts, Steven de Jonghe, Arnaud Marchand

Molecules 27:1052 (2022)10.3390/molecules27031052