Ashleigh Shannon
Chargée de recherche
Publications
2025
Nucleotide analogues and mpox: Repurposing the repurposable
Ashleigh Shannon, Bruno Canard
Antiviral Research 234:106057 (2025)10.1016/j.antiviral.2024.106057
2024
The effects of Remdesivir's functional groups on its antiviral potency and resistance against the SARS-CoV-2 polymerase
Bhawna Sama, Barbara Selisko, Camille Falcou, Véronique Fattorini, Géraldine Piorkowski, Franck Touret, Kim Donckers, Johan Neyts, Dirk Jochmans, Ashleigh Shannon, Bruno Coutard, Bruno Canard
Antiviral Research 232 (2024)10.1016/j.antiviral.2024.106034
2023
AT-752 targets multiple sites and activities on the Dengue virus replication enzyme NS5
Mikael Feracci, Cécilia Eydoux, Véronique Fattorini, Lea Lo Bello, Pierre Gauffre, Barbara Selisko, Priscila Sutto-Ortiz, Ashleigh Shannon, Hongjie Xia, Pei-Yong Shi, Mathieu Noel, Françoise Debart, Jean-Jacques Vasseur, Steve Good, Kai Lin, Adel Moussa, Jean-Pierre Sommadossi, Aurélie Chazot, Karine Alvarez, Jean-Claude Guillemot, Etienne Decroly, François Ferron, Bruno Canard
Antiviral Research 212:105574 (2023)10.1016/j.antiviral.2023.105574
2022
A second type of N7-guanine RNA cap methyltransferase in an unusual locus of a large RNA virus genome
Ashleigh Shannon, Bhawna Sama, Pierre Gauffre, Théo Guez, Françoise Debart, Jean-Jacques Vasseur, Etienne Decroly, Bruno Canard, François Ferron
Nucleic Acids Research 50:11186-11198 (2022)10.1093/nar/gkac876
A dual mechanism of action of AT-527 against SARS-CoV-2 polymerase
Ashleigh Shannon, Véronique Fattorini, Bhawna Sama, Barbara Selisko, Mikael Feracci, Camille Falcou, Pierre Gauffre, Priscila El Kazzi, Adrien Delpal, Etienne Decroly, Karine Alvarez, Cécilia Eydoux, Jean-Claude Guillemot, Adel Moussa, Steven S Good, Paolo La Colla, Kai Lin, Jean-Pierre Sommadossi, Yingxiao Zhu, Xiaodong Yan, Hui Shi, Francois Ferron, Bruno Canard
Nature Communications 13 (2022)10.1038/s41467-022-28113-1
2021
Structure and Sequence Requirements for RNA Capping at the Venezuelan Equine Encephalitis Virus RNA 5′ End
Oney Ortega Granda, Coralie Valle, Ashleigh Shannon, Etienne Decroly, Bruno Canard, Bruno Coutard, Nadia Rabah
Journal of Virology 95 (2021)10.1128/JVI.00777-21
A fluorescence-based high throughput-screening assay for the SARS-CoV RNA synthesis complex
Cecilia Eydoux, Veronique Fattorini, Ashleigh Shannon, Thi-Tuyet-Nhung Le, Bruno Didier, Bruno Canard, Jean-Claude Guillemot
Journal of Virological Methods 288:114013 (2021)10.1016/j.jviromet.2020.114013
2020
Drugs against SARS‐CoV ‐2: What do we know about their mode of action?
Coralie Valle, Baptiste Martin, Franck Touret, Ashleigh Shannon, Bruno Canard, Jean‐claude Guillemot, Bruno Coutard, Etienne Decroly
Reviews in Medical Virology 30:1-10 (2020)10.1002/rmv.2143
Rapid incorporation of Favipiravir by the fast and permissive viral RNA polymerase complex results in SARS-CoV-2 lethal mutagenesis
Ashleigh Shannon, Barbara Selisko, Nhung-Thi-Tuyet Le, Johanna Huchting, Franck Touret, Géraldine Piorkowski, Véronique Fattorini, Francois Ferron, Etienne Decroly, Chris Meier, Bruno Coutard, Olve Peersen, Bruno Canard
Nature Communications 11:4682 (2020)10.1038/s41467-020-18463-z
Remdesivir and SARS-CoV-2: Structural requirements at both nsp12 RdRp and nsp14 Exonuclease active-sites
Ashleigh Shannon, Nhung Thi-Tuyet Le, Barbara Selisko, Cecilia Eydoux, Karine Alvarez, Jean-Claude Guillemot, Etienne Decroly, Olve Peersen, Francois Ferron, Bruno Canard
Antiviral Research 178:104793 (2020)10.1016/j.antiviral.2020.104793
A N7-guanine RNA cap methyltransferase signature-sequence as a genetic marker of large genome, non-mammalian Tobaniviridae
Francois Ferron, Humberto Julio Debat, Ashleigh Shannon, Etienne Decroly, Bruno Canard
NAR Genomics and Bioinformatics 2 (2020)10.1093/nargab/lqz022
