Prix de thèse ANRS 2023 (Plus d’infos ici) :

Lauréate de la médaille d’argent 2020 de la Fondation “Méditerranée Infection” pour son travail de thèse!

Publications

2023

2023
ADDovenom: Thermostable Protein-Based ADDomer Nanoparticles as New Therapeutics for Snakebite Envenoming

Stefanie Menzies, Raquel Arinto-Garcia, Fernanda Gobbi Amorim, Iara Aimê Cardoso, Camille Abada, Thomas Crasset, Fabien Durbesson, Rebecca Edge, Priscila El-Kazzi, Sophie Hall, Damien Redureau, Richard Stenner, Johara Boldrini-França, Huan Sun, António Roldão, Paula Alves, Robert Harrison, Renaud Vincentelli, Imre Berger, Loïc Quinton, Nicholas Casewell, Christiane Schaffitzel

Toxins 15:673 (2023)10.3390/toxins15120673

2023
Interplay of RNA 2′-O-methylations with viral replication

Alice Decombe, Priscila El Kazzi, Etienne Decroly

Current Opinion in Virology 59:101302 (2023)10.1016/j.coviro.2023.101302

2023
2C protein of Enterovirus: key protein of viral replication and antiviral target

Priscila El Kazzi, Carole Yaacoub, Ziad Fajloun, Patrice Vanelle, Etienne Decroly, Bruno Coutard, Karine Barral

Virologie 27:35-49 (2023)10.1684/vir.2023.1002

2022

2022
Internal RNA 2′O-methylation in the HIV-1 genome counteracts ISG20 nuclease-mediated antiviral effect

Priscila El Kazzi, Nadia Rabah, Célia Chamontin, Lina Poulain, François Ferron, Françoise Debart, Bruno Canard, Dorothée Missé, Bruno Coutard, Sébastien Nisole, Etienne Decroly

Nucleic Acids Research (2022)10.1093/nar/gkac996

2022
Identification of potent inhibitors of arenavirus and SARS-CoV-2 exoribonucleases by fluorescence polarization assay

Sergio Hernández, Mikael Feracci, Carolina Trajano de Jesus, Priscila El Kazzi, Rafik Kaci, Laura Garlatti, Clemence Mondielli, Fabrice Bailly, Philippe Cotelle, Franck Touret, Xavier de Lamballerie, Bruno Coutard, Etienne Decroly, Bruno Canard, François Ferron, Karine Alvarez

Antiviral Research 204:105364 (2022)10.1016/j.antiviral.2022.105364

2022
A dual mechanism of action of AT-527 against SARS-CoV-2 polymerase

Ashleigh Shannon, Véronique Fattorini, Bhawna Sama, Barbara Selisko, Mikael Feracci, Camille Falcou, Pierre Gauffre, Priscila El Kazzi, Adrien Delpal, Etienne Decroly, Karine Alvarez, Cécilia Eydoux, Jean-Claude Guillemot, Adel Moussa, Steven S Good, Paolo La Colla, Kai Lin, Jean-Pierre Sommadossi, Yingxiao Zhu, Xiaodong Yan, Hui Shi, Francois Ferron, Bruno Canard

Nature Communications 13 (2022)10.1038/s41467-022-28113-1

2022
Fluoxetine targets an allosteric site in the enterovirus 2C AAA+ ATPase and stabilizes a ring-shaped hexameric complex

Daniel L Hurdiss, Priscila El Kazzi, Lisa Bauer, Nicolas Papageorgiou, Francois Ferron, Tim Donselaar, Arno L.W. van Vliet, Tatiana M Shamorkina, Joost Snijder, Bruno Canard, Etienne Decroly, Andrea Brancale, Tzviya Zeev-Ben-Mordehai, Friedrich Förster, Frank J.M. van Kuppeveld, Bruno Coutard

Science Advances 8 (2022)10.1126/sciadv.abj7615

2021

2021
Structure-function analysis of the nsp14 N7-guanine methyltransferase reveals an essential role in Betacoronavirus replication

Natacha S Ogando, Priscila El Kazzi, Jessika C Zevenhoven-Dobbe, Brenda W Bontes, Alice Decombe, Clara C S Posthuma, Volker Thiel, Bruno Canard, Francois Ferron, Etienne Decroly, Eric J Snijder

Proceedings of the National Academy of Sciences of the United States of America (2021)10.1101/2021.05.17.444407

2019

2019
Fluoxetine Inhibits Enterovirus Replication by Targeting the Viral 2C Protein in a Stereospecific Manner

Lisa Bauer, Roberto Manganaro, Birgit Zonsics, Jeroen Strating, Priscila El Kazzi, Moira Lorenzo Lopez, Rachel Ulferts, Clara van Hoey, Maria Mate, Thierry Langer, Bruno Coutard, Andrea Brancale, Frank van Kuppeveld

ACS Infectious Diseases 5:1609-1623 (2019)10.1021/acsinfecdis.9b00179