Frank Gondelaud
Ingénieur de recherche
Service : Techniques biophysiques
Service : Microscopie électronique en coloration négative et cryo
Publications
2026
Cysteine Redox State Governs the Condensation Pathway of Hendra Virus W Protein and Differentially Impacts Type I IFN and NF‐κB Signaling
Frank Gondelaud, Alexandre Lalande, Giulia Pesce, Auriane Bouchet, Carole Meunier, Christophe Bignon, Denis Ptchelkine, Yu Gu, Eva Ogire, Pierre‐yves Lozach, Denis Gerlier, Cyrille Mathieu, Sonia Longhi
Advanced Science 0:e23465 (2026)10.1002/advs.202523465
2025
A conserved motif in Henipavirus P/V/W proteins drives the fibrillation of the W protein from Hendra virus
Frank Gondelaud, Christophe Bignon, Denis Ptchelkine, Frédéric Carrière, Sonia Longhi
Protein Science 34 (2025)10.1002/pro.70085
Unraveling the molecular grammar and the structural transitions underlying the fibrillation of a viral fibrillogenic domain
Frank Gondelaud, Julien Leval, Lisha Arora, Anuja Walimbe, Christophe Bignon, Denis Ptchelkine, Stefania Brocca, Samrat Mukhopadyay, Sonia Longhi
Protein Science 34:e70068 (2025)10.1002/pro.70068
2024
PED in 2024: improving the community deposition of structural ensembles for intrinsically disordered proteins
Hamidreza Ghafouri, Tamas Lazar, Alessio del Conte, Luiggi G Tenorio Ku, Maria C Aspromonte, Pau Bernadó, Belén Chaves-Arquero, Lucia Beatriz Chemes, Damiano Clementel, Tiago N Cordeiro, Carlos A Elena-Real, Michael Feig, Isabella C Felli, Carlo Ferrari, Julie D Forman-Kay, Tiago Gomes, Frank Gondelaud, Claudiu C Gradinaru, Tâp Ha-Duong, Teresa Head-Gordon, Pétur O Heidarsson, Giacomo Janson, Gunnar Jeschke, Emanuela Leonardi, Zi Hao Liu, Sonia Longhi, Xamuel L Lund, Maria J Macias, Pau Martin-Malpartida, Davide Mercadante, Assia Mouhand, Gabor Nagy, María Victoria Nugnes, José Manuel Pérez-Cañadillas, Giulia Pesce, Roberta Pierattelli, Damiano Piovesan, Federica Quaglia, Sylvie Ricard-Blum, Paul Robustelli, Amin Sagar, Edoardo Salladini, Lucile Sénicourt, Nathalie Sibille, João M C Teixeira, Thomas E Tsangaris, Mihaly Varadi, Peter Tompa, Silvio C E Tosatto, Alexander Miguel Monzon
Nucleic Acids Research 52:D536-D544 (2024)10.1093/nar/gkad947
Dissecting Henipavirus W proteins conformational and fibrillation properties: contribution of their N‐ and C‐terminal constituent domains
Giulia Pesce, Frank Gondelaud, Denis Ptchelkine, Christophe Bignon, Patrick Fourquet, Sonia Longhi
FEBS Journal Online ahead of print (2024)10.1111/febs.17239
2023
Molecular Determinants of Fibrillation in a Viral Amyloidogenic Domain from Combined Biochemical and Biophysical Studies
Juliet F Nilsson, Hakima Baroudi, Frank Gondelaud, Giulia Pesce, Christophe Bignon, Denis Ptchelkine, Joseph Chamieh, Hervé Cottet, Andrey V Kajava, Sonia Longhi
International Journal of Molecular Sciences 24:399 (2023)10.3390/ijms24010399
Viral amyloids: New opportunities for antiviral therapeutic strategies
Frank Gondelaud, Pierre-Yves Lozach, Sonia Longhi
Current Opinion in Structural Biology 83:102706 (2023)10.1016/j.sbi.2023.102706
2022
Experimental Evidence of Intrinsic Disorder and Amyloid Formation by the Henipavirus W Proteins
Giulia Pesce, Frank Gondelaud, Denis Ptchelkine, Juliet F Nilsson, Christophe Bignon, Jérémy Cartalas, Patrick Fourquet, Sonia Longhi
International Journal of Molecular Sciences 23:923 (2022)10.3390/ijms23020923
Functional benefit of structural disorder for the replication of measles, Nipah and Hendra viruses
Frank Gondelaud, Giulia Pesce, Juliet F. Nilsson, Christophe Bignon, Denis Ptchelkine, Denis Gerlier, Cyrille Mathieu, Sonia Longhi
Essays in Biochemistry 66:915-934 (2022)10.1042/EBC20220045
2021
Identification of a Region in the Common Amino-terminal Domain of Hendra Virus P, V, and W Proteins Responsible for Phase Transition and Amyloid Formation
Edoardo Salladini, Frank Gondelaud, Juliet Nilsson, Giulia Pesce, Christophe Bignon, Maria Grazia Murrali, Roxane Fabre, Roberta Pierattelli, Andrey Kajava, Branka Horvat, Denis Gerlier, Cyrille Mathieu, Sonia Longhi
Biomolecules 11:1324 (2021)10.3390/biom11091324
Extended disorder at the cell surface: The conformational landscape of the ectodomains of syndecans
Frank Gondelaud, Mathilde Bouakil, Aurélien Le Fèvre, Adriana Erica Miele, Fabien Chirot, Bertrand Duclos, Adam Liwo, Sylvie Ricard-Blum
Matrix Biology Plus 12:100081 (2021)10.1016/j.mbplus.2021.100081
2020
Sialic acids rather than glycosaminoglycans affect normal and sickle red blood cell rheology by binding to four major sites on fibrinogen
Frank Gondelaud, Philippe Connes, Elie Nader, Céline Renoux, Romain Fort, Alexandra Gauthier, Philippe Joly, Sylvie Ricard-Blum
American Journal of Hematology 95:E77-E80 (2020)10.1002/ajh.25718
2019
Structures and interactions of syndecans
Frank Gondelaud, Sylvie Ricard-Blum
FEBS Journal 286:2994-3007 (2019)10.1111/febs.14828
