Collection AFMB dans HAL: ici

2020

2020
Interactomic affinity profiling by holdup assay: Acetylation and distal residues impact the PDZome-binding specificity of PTEN phosphatase

Pau Jané, Gergő Gógl, Camille Kostmann, Goran Bich, Virginie Girault, Célia Caillet-Saguy, Pascal Eberling, Renaud Vincentelli, Nicolas Wolff, Gilles Travé, Yves Nominé

PLoS ONE 15:e0244613 (2020)10.1371/journal.pone.0244613

2020
Galactosaminogalactan activates the inflammasome to provide host protection

Benoit Briard, Thierry Fontaine, Parimal Samir, David Place, Laetitia Muszkieta, R. Malireddi, Rajendra Karki, Shelbi Christgen, Perrine Bomme, Peter Vogel, Rémi Beau, Emilia Mellado, Oumaima Ibrahim-Granet, Bernard Henrissat, Ravi Kalathur, Cam Robinson, Jean-Paul Latgé, Thirumala-Devi Kanneganti

Nature 588:688-692 (2020)10.1038/s41586-020-2996-z

2020
Capping pores of alphavirus nsP1 gate membranous viral replication factories

Rhian Jones, Gabriel Bragagnolo, Rocío Arranz, Juan Reguera

Nature 589:615-619 (2020)10.1038/s41586-020-3036-8

2020
PED in 2021: a major update of the protein ensembledatabase for intrinsically disordered proteins

Tamas Lazar, Elizabeth Martínez-Pérez, Federica Quaglia, András Hatos, Lucía B Chemes, Javier A Iserte, Nicolás A Méndez, Nicolás A Garrone, Tadeo E Saldaño, Julia Marchetti, Ana Julia Velez Rueda, Pau Bernadó, Martin Blackledge, Tiago N Cordeiro, Eric Fagerberg, Julie D Forman-Kay, Maria S Fornasari, Toby J Gibson, Gregory-Neal W Gomes, Claudiu C Gradinaru, Teresa Head-Gordon, Malene Ringkjøbing Jensen, Edward A Lemke, Sonia Longhi, Cristina Marino-Buslje, Giovanni Minervini, Tanja Mittag, Alexander Miguel Monzon, Rohit V Pappu, Gustavo Parisi, Sylvie Ricard-Blum, Kiersten M Ruff, Edoardo Salladini, Marie Skepö, Dmitri Svergun, Sylvain D Vallet, Mihaly Varadi, Peter Tompa, Silvio C E Tosatto, Damiano Piovesan, Rodolfo A Ugalde

Nucleic Acids Research (2020)10.1093/nar/gkaa1021

2020
Pharmacological inhibition of syntenin PDZ2 domain impairs breast cancer cell activities and exosome loading with syndecan and EpCAM cargo

R. Leblanc, R. Kashyap, K. Barral, A.L. Egea‐jimenez, D. Kovalskyy, M. Feracci, M. Garcia, C. Derviaux, S. Betzi, R. Ghossoub, M. Platonov, P. Roche, X. Morelli, L. Hoffer, Pascale Zimmermann

Journal of Extracellular Vesicles 10 (2020)10.1002/jev2.12039

2020
Metabolism of multiple glycosaminoglycans by Bacteroides thetaiotaomicron is orchestrated by a versatile core genetic locus

Didier Ndeh, Arnaud Baslé, Henrik Strahl, Urszula Mcclurgg, Bernard Henrissat, Nicolas Terrapon, Alan Cartmell

Nature Communications 11 (2020)10.1038/s41467-020-14509-4

2020
Tracing the origins of SARS-CoV-2 in coronavirus phylogenies

Erwan Sallard, José Halloy, Didier Casane, Etienne Decroly, Jacques van Helden

Médecine/Sciences 36 (2020)10.1051/medsci/2020123

2020
Display of the Human Mucinome With Defined O-Glycans by Gene Engineered Cells

Nason Rebecca, Bull, Christian, Hiren J Joshi, Konstantinidi, Andriana, Renaud Vincentelli, Bernard Henrissat, Vakhrushev, Sergey, Henrik Clausen, Yoshiki Narimatsu

Glycobiology (2020)

2020
Microbiota-directed fibre activates both targeted and secondary metabolic shifts in the distal gut

Leszek Michalak, John Christian Gaby, Leidy Lagos, Sabina Leanti La Rosa, Torgeir Hvidsten, Catherine Tétard-Jones, William G T Willats, Nicolas Terrapon, Vincent Lombard, Bernard Henrissat, Johannes Dröge, Magnus Øverlie Arntzen, Live Heldal Hagen, Margareth Øverland, Phillip Pope, Bjørge Westereng

Nature Communications 11 (2020)10.1038/s41467-020-19585-0

2020
Crystal structure of Type IX secretion system PorE C-terminal domain from Porphyromonas gingivalis in complex with a peptidoglycan fragment

Nhung Thi Trang Trinh, Hieu Quang Tran, Quyen van Dong, Christian Cambillau, Alain Roussel, Philippe Leone

Scientific Reports 10 (2020)10.1038/s41598-020-64115-z

2020
Large-scale genome sequencing of mycorrhizal fungi provides insights into the early evolution of symbiotic traits

Shingo Miyauchi, Enikő Kiss, Alan Kuo, Elodie Drula, Annegret Kohler, Marisol Sánchez-García, Emmanuelle Morin, Bill Andreopoulos, Kerrie Barry, Gregory Bonito, Marc Buée, Akiko Carver, Cindy Chen, Nicolas Cichocki, Alicia Clum, David Culley, Pedro Crous, Laure Fauchery, Mariangela Girlanda, Richard Hayes, Zsófia Kéri, Kurt Labutti, Anna Lipzen, Vincent Lombard, Jon Magnuson, François Maillard, Claude C. Murat, Matt Nolan, Robin Ohm, Jasmyn Pangilinan, Maíra de Freitas Pereira, Silvia Perotto, Martina Peter, Stephanie Pfister, Robert Riley, Yaron Sitrit, J. Benjamin Stielow, Gergely Szöllősi, Lucia Žifčáková, Martina Štursová, Joseph Spatafora, Leho Tedersoo, Lu-Min Vaario, Akiyoshi Yamada, Mi Yan, Pengfei Wang, Jianping Xu, Tom Bruns, Petr Baldrian, Rytas Vilgalys, Christophe Dunand, Bernard Henrissat, Igor Grigoriev, David Hibbett, László Nagy, Francis M. Martin

Nature Communications 11 (2020)10.1038/s41467-020-18795-w

2020
Genome sequencing of Rigidoporus microporus provides insights on genes important for wood decay, latex tolerance and interspecific fungal interactions

Abbot Oghenekaro, Andriy Kovalchuk, Tommaso Raffaello, Susana Camarero, Markus Gressler, Bernard Henrissat, Juna Lee, Mengxia Liu, Angel Martínez, Otto Miettinen, Sirma Mihaltcheva, Jasmyn Pangilinan, Fei Ren, Robert Riley, Francisco Javier Ruiz-Dueñas, Ana Serrano, Michael Thon, Zilan Wen, Zhen Zeng, Kerrie Barry, Igor Grigoriev, Francis Martin, Fred Asiegbu

Scientific Reports 10 (2020)10.1038/s41598-020-62150-4

2020
Predicting substitutions to modulate disorder and stability in coiled-coils

Yasaman Karami, Paul Saighi, Rémy Vanderhaegen, Denis Gerlier, Sonia Longhi, Elodie Laine, Alessandra Carbone

BMC Bioinformatics 21 (2020)10.1186/s12859-020-03867-x

2020
Predicting substitutions to modulate disorder and stability in coiled-coils

Yasaman Karami, Paul Saighi, Rémy Vanderhaegen, Denis Gerlier, Sonia Longhi, Elodie Laine, Alessandra Carbone

BMC Bioinformatics 21:573 (2020)10.1186/s12859-020-03867-x

2020
A comparative genomics study of 23 Aspergillus species from section Flavi

Inge Kjærbølling, Tammi Vesth, Jens Frisvad, Jane Nybo, Sebastian Theobald, Sara Kildgaard, Thomas Isbrandt Petersen, Alan Kuo, Atsushi Sato, Ellen Lyhne, Martin Kogle, Ad Wiebenga, Roland Kun, Ronnie Lubbers, Miia Mäkelä, Kerrie Barry, Mansi Chovatia, Alicia Clum, Chris Daum, Sajeet Haridas, Guifen He, Kurt Labutti, Anna Lipzen, Stephen Mondo, Jasmyn Pangilinan, Robert Riley, Asaf Salamov, Blake Simmons, Jon Magnuson, Bernard Henrissat, Uffe Mortensen, Thomas Larsen, Ronald de Vries, Igor Grigoriev, Masayuki Machida, Scott Baker, Mikael Andersen

Nature Communications 11 (2020)10.1038/s41467-019-14051-y

2020
2020
Wine phenolic compounds differently affect the host-killing activity of two lytic bacteriophages infecting the lactic acid bacterium oenococcus oeni

Cécile Philippe, Amel Chaib, Fety Jaomanjaka, Stéphanie Cluzet, Aurélie Lagarde, Patricia Ballestra, Alain Decendit, Melina Petrel, Olivier Claisse, Adeline Goulet, Christian C. Cambillau, Claire Le Marrec

Viruses 12:1-19 (2020)10.3390/v12111316

2020
α-Galactosidase and Sucrose-Kinase Relationships in a Bi-functional AgaSK Enzyme Produced by the Human Gut Symbiont Ruminococcus gnavus E1

Mickaël Lafond, Alexandra Tauzin, Laëtitia Bruel, Elisabeth Laville, Vincent Lombard, Jérémy Esque, Isabelle André, Nicolas Vidal, Frédérique Pompeo, Nathalie Quinson, Josette Perrier, Michel Fons, Gabrielle Potocki-Veronese, Thierry Giardina

Frontiers in Microbiology 11:579521 (2020)10.3389/fmicb.2020.579521

2020
Ensemble description of the intrinsically disordered N-terminal domain of the Nipah virus P/V protein from combined NMR and SAXS

Marco Schiavina, Edoardo Salladini, Maria Grazia Murrali, Giancarlo Tria, Isabella Felli, Roberta Pierattelli, Sonia Longhi

Scientific Reports 10 (2020)10.1038/s41598-020-76522-3

2020
Drugs against SARS‐CoV ‐2: What do we know about their mode of action?

Coralie Valle, Baptiste Martin, Franck Touret, Ashleigh Shannon, Bruno Canard, Jean‐claude Guillemot, Bruno Coutard, Etienne Decroly

Reviews in Medical Virology 30:1-10 (2020)10.1002/rmv.2143

2020
Synthesis and biological evaluation of novel flexible nucleoside analogues that inhibit flavivirus replication in vitro

Joy Thames, Charles Waters, Coralie Valle, Marcella Bassetto, Wahiba Aouadi, Baptiste Martin, Barbara Selisko, Arissa Falat, Bruno Coutard, Andrea Brancale, Bruno Canard, Etienne Decroly, Katherine Seley-Radtke

Bioorganic and Medicinal Chemistry Letters 28:115713 (2020)10.1016/j.bmc.2020.115713

2020
Mutations on VEEV nsP1 relate RNA capping efficiency to ribavirin susceptibility

Nadia Rabah, Oney Ortega Granda, Gilles Quérat, Bruno Canard, Etienne Decroly, Bruno Coutard

Antiviral Research 182:104883 (2020)10.1016/j.antiviral.2020.104883

2020
The CWPS Rubik’s cube: Linking diversity of cell wall polysaccharide structures with the encoded biosynthetic machinery of selected Lactococcus lactis strains.

Jennifer Mahony, Cyril Frantzen, Evgeny Vinogradov, Irina Sadovskaya, Ilias Theodorou, Philip Kelleher, Marie‐pierre Chapot‐chartier, Christian C. Cambillau, Helge Holo, Douwe Van Sinderen

Molecular Microbiology 114:582-596 (2020)10.1111/mmi.14561

2020
Structure-based drug repositioning over the human TMPRSS2 protease domain: search for chemical probes able to repress SARS-CoV-2 Spike protein cleavages

Natesh Singh, Etienne Decroly, Abdel-Majid Khatib, Bruno Villoutreix

European Journal of Pharmaceutical Sciences 153:105495 (2020)10.1016/j.ejps.2020.105495

2020
The CWPS Rubik’s cube: Linking diversity of cell wall polysaccharide structures with the encoded biosynthetic machinery of selected Lactococcus lactis strains.

Jennifer Mahony, Cyril Frantzen, Evgeny Vinogradov, Irina Sadovskaya, Ilias Theodorou, Philip Kelleher, Marie‐pierre Chapot‐chartier, Christian C. Cambillau, Helge Holo, Douwe Van Sinderen

Molecular Microbiology 114:582-596 (2020)10.1111/mmi.14561

2020
The CWPS Rubik’s cube: Linking diversity of cell wall polysaccharide structures with the encoded biosynthetic machinery of selected Lactococcus lactis strains

Jennifer Mahony, Cyril Frantzen, Evgeny Vinogradov, Irina Sadovskaya, Ilias Theodorou, Philip Kelleher, Marie‐pierre Chapot-Chartier, Christian Cambillau, Helge Holo, Douwe Sinderen

Molecular Microbiology 114:582-596 (2020)10.1111/mmi.14561

2020
Notion d’employeur (sécurité sociale)

Laetitia Driguez

Europe comm. 299 (2020)

2020
The neuroligins and the synaptic pathway in Autism Spectrum Disorder.

Laura Trobiani, Maria Meringolo, Tamara Diamanti, Yves Bourne, Pascale Marchot, Giuseppina Martella, Luciana Dini, Antonio Pisani, Antonella de Jaco, Paola Bonsi

Neuroscience and Biobehavioral Reviews 119:37-51 (2020)10.1016/j.neubiorev.2020.09.017

2020
Rapid incorporation of Favipiravir by the fast and permissive viral RNA polymerase complex results in SARS-CoV-2 lethal mutagenesis

Ashleigh Shannon, Barbara Selisko, Nhung-Thi-Tuyet Le, Johanna Huchting, Franck Touret, Géraldine Piorkowski, Véronique Fattorini, Francois Ferron, Etienne Decroly, Chris Meier, Bruno Coutard, Olve Peersen, Bruno Canard

Nature Communications 11:4682 (2020)10.1038/s41467-020-18463-z

2020
Biochemical characterization of a glycosyltransferase Gtf3 from Mycobacterium smegmatis: a case study of improved protein solubilization

Mahfoud Bakli, Loukmane Karim, Nassima Mokhtari-Soulimane, Hafida Merzouk, Florence Vincent

3 Biotech 10 (2020)10.1007/s13205-020-02431-x

2020
The Ig-like domain of Punctin/MADD-4 is the primary determinant for interaction with the ectodomain of neuroligin NLG-1

Semeli Platsaki, Xin Zhou, Bérangère Pinan-Lucarré, Vincent Delauzun, Haijun Tu, Pascal Mansuelle, Patrick Fourquet, Yves Bourne, Jean-Louis Bessereau, Pascale Marchot

Journal of Biological Chemistry 16267-16279. (2020)10.1074/jbc.RA120.014591

2020
The de.NBI / ELIXIR-DE training platform - Bioinformatics training in Germany and across Europe within ELIXIR

Daniel Wibberg, Bérénice Batut, Peter Belmann, Jochen Blom, Frank Oliver Glöckner, Björn Grüning, Nils Hoffmann, Nils Kleinbölting, René Rahn, Maja Rey, Uwe Scholz, Malvika Sharan, Andreas Tauch, Ulrike Trojahn, Björn Usadel, Oliver Kohlbacher

F1000Research 8:1877 (2020)10.12688/f1000research.20244.2

2020
Snapshots of ADp-ribose bound to Getah virus macro domain reveal an intriguing choreography

Ana Sofia Ferreira-Ramos, Gerlind Sulzenbacher, Bruno Canard, Bruno Coutard

Scientific Reports 10 (2020)10.1038/s41598-020-70870-w

2020
Relevance of Electrostatic Charges in Compactness, Aggregation, and Phase Separation of Intrinsically Disordered Proteins

Greta Bianchi, Sonia Longhi, Rita Grandori, Stefania Brocca

International Journal of Molecular Sciences 21:6208 (2020)10.3390/ijms21176208

2020
Synthesis of adenine dinucleosides SAM analogs as specific inhibitors of SARS-CoV nsp14 RNA cap guanine-N7-methyltransferase

Rostom Ahmed‐belkacem, Priscila Sutto-Ortiz, Mathis Guiraud, Bruno Canard, Jean-Jacques Vasseur, Etienne Decroly, Francoise Debart

European Journal of Medicinal Chemistry 201:112557 (2020)10.1016/j.ejmech.2020.112557

2020
Characterization of the CAZy Repertoire from the Marine-Derived Fungus Stemphylium lucomagnoense in Relation to Saline Conditions

Wissal Ben Ali, David Navarro, Abhishek Kumar, Elodie Drula, Annick Turbé-Doan, Lydie Oliveira Correia, Stéphanie Baumberger, Emmanuel Bertrand, Craig Faulds, Bernard Henrissat, Giuliano Sciara, Tahar Mechichi, Eric Record

Marine drugs 18:1-21 (2020)10.3390/md18090461

2020
Utilization of Galectins by Pathogens for Infection

Diyoly Ayona, Pierre-Edouard Fournier, Bernard Henrissat, Benoit Desnues

Frontiers in Immunology 11 (2020)10.3389/fimmu.2020.01877

2020
A Venomics Approach Coupled to High-Throughput Toxin Production Strategies Identifies the First Venom-Derived Melanocortin Receptor Agonists

Steve Reynaud, Justyna Ciolek, Michel Degueldre, Natalie Saez, Ana Filipa Sequeira, Yoan Duhoo, Joana Brás, Herve Meudal, Miguel Cabo Díez, Victoria Fernández Pedrosa, Marion Verdenaud, Julia Boeri, Oscar Henrique Pereira Ramos, Frédéric Ducancel, Margot Vanden Driessche, Rudy Fourmy, Aude Violette, Grégory Upert, Gilles Mourier, Annette Beck-Sickinger, Karin Mörl, Celine Landon, Carlos M.G.A. Fontes, Rebeca Miñambres Herráiz, Ricardo Rodríguez de La Vega, Steve Peigneur, Jan Tytgat, Loïc Quinton, Edwin de Pauw, Renaud Vincentelli, Denis Servent, Nicolas Gilles

Journal of Medicinal Chemistry 63:8250-8264 (2020)10.1021/acs.jmedchem.0c00485

2020
Structural Insights into Lactococcal Siphophage p2 Baseplate Activation Mechanism

Silvia Spinelli, Denise Tremblay, Sylvain Moineau, Christian Cambillau, Adeline Goulet

Viruses 12 (2020)10.3390/v12080878

2020
In vitro screening of a FDA approved chemical library reveals potential inhibitors of SARS-CoV-2 replication

Franck Touret, Magali Gilles, Karine Barral, Antoine Nougairède, Jacques van Helden, Etienne Decroly, Xavier de Lamballerie, Bruno Coutard

Scientific Reports 10:13093 (2020)10.1038/s41598-020-70143-6

2020
Extracellular vesicles as a platform to study cell-surface membrane proteins

Vincent Delauzun, Beatrice Amigues, Anais Gaubert, Philippe Leone, Magali Grange, Laurent Gauthier, Alain Roussel

Methods 180:35-44 (2020)10.1016/j.ymeth.2020.03.004

2020
A mutation map for human glycoside hydrolase genes

Lars Hansen, Diab Husein, Birthe Gericke, Torben Hansen, Oluf Pedersen, Mitali Tambe, Hudson Freeze, Hassan Naim, Bernard Henrissat, Hans Wandall, Henrik Clausen, Eric Bennett

Glycobiology 30:500-515 (2020)10.1093/glycob/cwaa010

2020
Brothers in Arms: Structure, Assembly and Function of Arenaviridae Nucleoprotein

Nicolas Papageorgiou, Maria Spiliopoulou, Thi-Hong van Nguyen, Afroditi Vaitsopoulou, Elsie Yekwa Laban, Karine Alvarez, Irene Margiolaki, Bruno Canard, Francois Ferron

Viruses 12:772 (2020)10.3390/v12070772

2020
Isolation and Characterization of Extracellular Vesicles Secreted In Vitro by Porcine Microbiota

Leidy Lagos, Sabina Leanti La Rosa, Magnus Ø. Arntzen, Ragnhild Ånestad, Nicolas Terrapon, John Christian Gaby, Bjørge Westereng

Microorganisms 8:983 (2020)10.3390/microorganisms8070983

2020
Novel Class of Chikungunya Virus Small Molecule Inhibitors That Targets the Viral Capping Machinery

Rana Abdelnabi, Kristina Kovacikova, Julia Moesslacher, Kim Donckers, Verena Battisti, Pieter Leyssen, Thierry Langer, Gerhard Puerstinger, Gilles Quérat, Changqing Li, Etienne Decroly, Ali Tas, Arnaud Marchand, Patrick Chaltin, Bruno Coutard, Martijn van Hemert, Johan Neyts, Leen Delang

Antimicrobial Agents and Chemotherapy 64 (2020)10.1128/AAC.00649-20

2020
Novel Genus of Phages Infecting Streptococcus thermophilus : Genomic and Morphological Characterization

Cécile Philippe, Sébastien Levesque, Moïra Dion, Denise Tremblay, Philippe Horvath, Natascha Lüth, Christian Cambillau, Charles Franz, Horst Neve, Christophe Fremaux, Knut Heller, Sylvain Moineau

Applied and Environmental Microbiology 86 (2020)10.1128/AEM.00227-20

2020
Densité de nids de Myrmica en tourbière : exemple de la tourbière de Jouvion (Puy-de-Dôme)

Luc Belenguier, Marine Kreder², Vincent Lombard, Mathilde Poussin, Christophe Galkovsky

BIOM - Revue scientifique pour la biodiversité du Massif central 1:35-48 (2020)10.18145/biom.v1i1.255

2020
Conserved white rot enzymatic mechanism for wood decay in the Basidiomycota genus Pycnoporus

Shingo Miyauchi, Hayat Hage, Elodie Drula, Laurence Lesage-Meessen, Jean-Guy Berrin, David Navarro, Anne Favel, Delphine Chaduli, Sacha Grisel, Mireille Haon, François Piumi, Anthony Levasseur, Anne Lomascolo, Steven Ahrendt, Kerrie Barry, Kurt Labutti, Didier Chevret, Chris Daum, Jérôme J. Mariette, Christophe Klopp, Daniel Cullen, Ronald de Vries, Allen Gathman, Matthieu Hainaut, Bernard Henrissat, Kristiina Hildén, Ursula Kues, Walt Lilly, Anna Lipzen, Miia Mäkelä, Angel Martinez, Melanie Morel-Rouhier, Emmanuelle Morin, Jasmyn Pangilinan, Arthur Ram, Han Wösten, Francisco Ruiz-Dueñas, Robert Riley, Eric Record, Igor Grigoriev, Marie-Noelle Rosso

DNA Research (2020)10.1093/dnares/dsaa011

2020
Revisiting the host adhesion determinants of Streptococcus thermophilus siphophages

Katherine Lavelle, Adeline Goulet, Brian Mcdonnell, Silvia Spinelli, Douwe Van Sinderen, Jennifer Mahony, Christian Cambillau

Microbial Biotechnology 13:1765-1779 (2020)10.1111/1751-7915.13593

2020
Remdesivir and SARS-CoV-2: Structural requirements at both nsp12 RdRp and nsp14 Exonuclease active-sites

Ashleigh Shannon, Nhung Thi-Tuyet Le, Barbara Selisko, Cecilia Eydoux, Karine Alvarez, Jean-Claude Guillemot, Etienne Decroly, Olve Peersen, Francois Ferron, Bruno Canard

Antiviral Research 178:104793 (2020)10.1016/j.antiviral.2020.104793

2020
101 Dothideomycetes genomes: A test case for predicting lifestyles and emergence of pathogens

S. Haridas, R. Albert, M. Binder, J. Bloem, K. Labutti, A. Salamov, B. Andreopoulos, S.E. Baker, K. Barry, G. Bills, B.H. Bluhm, C. Cannon, R. Castanera, D.E. Culley, C. Daum, D. Ezra, J.B. González, Bernard Henrissat, A. Kuo, C. Liang, A. Lipzen, F. Lutzoni, J. Magnuson, S.J. Mondo, M. Nolan, R.A. Ohm, J. Pangilinan, H.-J. Park, L. Ramírez, M. Alfaro, H. Sun, A. Tritt, Y. Yoshinaga, L.-H. Zwiers, B.G. Turgeon, S.B. Goodwin, J.W. Spatafora, P.W. Crous, I.V. Grigoriev

Studies in Mycology 96:141-153 (2020)10.1016/j.simyco.2020.01.003

2020
Discovery, SAR study and ADME properties of methyl 4-amino-3-cyano-1-(2-benzyloxyphenyl)-1 H -pyrazole-5-carboxylate as an HIV-1 replication inhibitor

Jeanne Fichez, Cathia Soulié, Laurent Le Corre, Sophie Sayon, Stéphane Priet, Karine Alvarez, Olivier Delelis, Patrick Gizzi, Guillaume Prestat, Christine Gravier-Pelletier, Anne-Geneviève Marcelin, Vincent Calvez, Patricia Busca

RSC Medicinal Chemistry 11:577-582 (2020)10.1039/D0MD00025F

2020
Infection cushions of Fusarium graminearum are fungal arsenals for wheat infection

Michael Mentges, Anika Glasenapp, Marike Boenisch, Sascha Malz, Bernard Henrissat, Rasmus J.N. Frandsen, Ulrich Guldener, Martin Münsterkötter, Jörg Bormann, Marc‐henri Lebrun, Wilhelm Schäfer, Ana Lilia Martinez‐rocha

Molecular Plant Pathology 21:1070-1087 (2020)10.1111/mpp.12960

2020
2020
Diversity of molecular mechanisms used by anti-CRISPR proteins: the tip of an iceberg?

Pierre Hardouin, Adeline Goulet

Biochemical Society Transactions 48:507-516 (2020)10.1042/BST20190638

2020
Antiviral activity of the natural alkaloid anisomycin against dengue and Zika viruses

V.M. Quintana, B. Selisko, J.E. Brunetti, C. Eydoux, J.C. Guillemot, B. Canard, E.B. Damonte, J.G. Julander, V. Castilla

Antiviral Research 176:104749 (2020)10.1016/j.antiviral.2020.104749

2020
Dual Specificity PDZ- and 14-3-3-Binding Motifs: A Structural and Interactomics Study

Gergo Gogl, Pau Jane, Célia Caillet-Saguy, Camille Kostmann, Goran Bich, Alexandra Cousido-Siah, Laszlo Nyitray, Renaud Vincentelli, Nicolas Wolff, Yves Nominé, Nikolai Sluchanko, Gilles Travé

Structure 28:747 (2020)10.1016/j.str.2020.03.010

2020
Antiviral activity of the natural alkaloid anisomycin against dengue and Zika viruses

V.M. Quintana, B. Selisko, J.E. Brunetti, C. Eydoux, J.C. Guillemot, B. Canard, E.B. Damonte, J.G. Julander, V. Castilla

Antiviral Research 176:104749 (2020)10.1016/j.antiviral.2020.104749

2020
Discovery of a Fungal Copper Radical Oxidase with High Catalytic Efficiency toward 5-Hydroxymethylfurfural and Benzyl Alcohols for Bioprocessing

Yann Mathieu, Wendy Offen, Stephanie Forget, Luisa Ciano, Alexander Holm Viborg, Elena Blagova, Bernard Henrissat, Paul Walton, Gideon Davies, Harry Brumer

ACS Catalysis 10:3042-3058 (2020)10.1021/acscatal.9b04727

2020
A N7-guanine RNA cap methyltransferase signature-sequence as a genetic marker of large genome, non-mammalian Tobaniviridae

Francois Ferron, Humberto Julio Debat, Ashleigh Shannon, Etienne Decroly, Bruno Canard

NAR Genomics and Bioinformatics 2 (2020)10.1093/nargab/lqz022

2020
Discovery of hyperstable carbohydrate‐active enzymes through metagenomics of extreme environments

Andrea Strazzulli, Beatrice Cobucci‐ponzano, Roberta Iacono, Rosa Giglio, Luisa Maurelli, Nicola Curci, Corinna Schiano‐di‐cola, Annalisa Santangelo, Patrizia Contursi, Vincent Lombard, Bernard Henrissat, Federico M Lauro, Carlos M.G.A. Fontes, Marco Moracci

FEBS Journal 287:1116-1137 (2020)10.1111/febs.15080

2020
Design, Synthesis and Discovery of N,N’ ‐Carbazoyl‐aryl‐urea Inhibitors of Zika NS5 Methyltransferase and Virus Replication

Sharon Spizzichino, Giulio Mattedi, Kate Lauder, Coralie Valle, Wahiba Aouadi, Bruno Canard, Etienne Decroly, Suzanne Kaptein, Johan Neyts, Carl Graham, Zakary Sule, David Barlow, Romano Silvestri, Daniele Castagnolo

ChemMedChem 15:385-390 (2020)10.1002/cmdc.201900533

2020
The spike glycoprotein of the new coronavirus 2019-nCoV contains a furin-like cleavage site absent in CoV of the same clade

Bruno Coutard, Coralie Valle, Xavier de Lamballerie, Bruno Canard, Nabil G Seidah, Etienne Decroly

Antiviral Research 176:104742 (2020)10.1016/j.antiviral.2020.104742

2020
Versatile and robust genome editing with Streptococcus thermophilus CRISPR1-Cas9

Daniel Agudelo, Sophie Carter, Minja Velimirovic, Alexis Duringer, Jean-François Rivest, Sébastien Levesque, Jérémy Loehr, Mathilde Mouchiroud, Denis Cyr, Paula Waters, Mathieu Laplante, Sylvain Moineau, Adeline Goulet, Yannick Doyon

Genome Research 30:107-117 (2020)10.1101/gr.255414.119

2020
Genomic analysis enlightens agaricales Lifestyle Evolution and increasing peroxidase diversity

Francisco Ruiz-Dueñas, José Barrasa, Marisol Sánchez-García, Susana Camarero, Shingo Miyauchi, Ana Serrano, Dolores Linde, Rashid Babiker, Elodie Drula, Iván Ayuso-Fernández, Remedios Pacheco, Guillermo Padilla, Patricia Ferreira, Jorge Barriuso, Harald Kellner, Raúl Castanera, Manuel Alfaro, Lucía Ramirez, Antonio Pisabarro, Robert Riley, Alan Kuo, William Andreopoulos, Kurt Labutti, Jasmyn Pangilinan, Andrew Tritt, Anna Lipzen, Guifen He, Mi Yan, Vivian Ng, Igor Grigoriev, Daniel Cullen, Marie-Noëlle Rosso, Bernard Henrissat, David Hibbett, Angel Martínez

Molecular Biology and Evolution 38:p. 1428-1446 (2020)10.1093/molbev/msaa301

2020
Carneic Acids from an Endophytic Phomopsis sp. as Dengue Virus Polymerase Inhibitors

Laure-Anne Peyrat, Véronique Eparvier, Cecilia Eydoux, Jean-Claude Guillemot, Marc Litaudon, Didier Stien

Journal of Natural Products 83:2330-2336 (2020)10.1021/acs.jnatprod.9b01169

2020
A catalog of microbial genes from the bovine rumen unveils a specialized and diverse biomass-degrading environment

Junhua Li, Huanzi Zhong, Yuliaxis Y. Ramayo-Caldas, Nicolas Terrapon, Vincent Lombard, Gabrielle Potocki-Veronese, Jordi Estellé, Milka Popova, Ziyi Yang, Hui Zhang, Fang Li, Shanmei Tang, Fangming Yang, Weineng Chen, Bing Chen, Jiyang Li, Jing Guo, Cécile Martin, Emmanuelle Maguin, Xun Xu, Huanming Yang, Jian Wang, Lise Madsen, Karsten Kristiansen, Bernard Henrissat, Stanislav S. Ehrlich, Diego Morgavi

GigaScience 9:1-15 (2020)10.1093/gigascience/giaa057

2020
Analysis of the diversity of the glycoside hydrolase family 130 in mammal gut microbiomes reveals a novel mannoside-phosphorylase function

Ao Li, Elisabeth Laville, Laurence Tarquis, Vincent Lombard, David Ropartz, Nicolas Terrapon, Bernard Henrissat, David Guieysse, Jeremy Esque, Julien Durand, Diego Morgavi, Gabrielle Potocki-Veronese

Microbial Genomics 6:1-14 (2020)10.1099/mgen.0.000404

2020
A fungal family of lytic polysaccharide monooxygenase-like copper proteins

Aurore Labourel, Kristian Frandsen, Feng Zhang, Nicolas Brouilly, Sacha Grisel, Mireille Haon, Luisa Ciano, David Ropartz, Mathieu Fanuel, Francis Martin, David Navarro, Marie-Noelle Rosso, Tobias Tandrup, Bastien Bissaro, Katja S. Johansen, Anastasia Zerva, Paul H. Walton, Bernard Henrissat, Leila Lo Leggio, Jean-Guy Berrin

Nature Chemical Biology 16:345-350 (2020)10.1038/s41589-019-0438-8

2020
Investigating host-microbiome interactions by droplet based microfluidics

Alexandra S Tauzin, Mariana Rangel Pereira, Liisa D van Vliet, Pierre-Yves Colin, Elisabeth Laville, Jeremy Esque, Sandrine Laguerre, Bernard Henrissat, Nicolas Terrapon, Vincent Lombard, Marion Leclerc, Joël Doré, Florian Hollfelder, Gabrielle Potocki-Veronese

Microbiome 8 (2020)10.1186/s40168-020-00911-z

2020
Harvesting of Prebiotic Fructooligosaccharides by Nonbeneficial Human Gut Bacteria

Zhi Wang, Alexandra S. Tauzin, Elisabeth Laville, Pietro Tedesco, Fabien Letisse, Nicolas Terrapon, Pascale Lepercq, Myriam Mercade, Gabrielle Potocki-Veronese

mSphere 5:26 p. (2020)10.1128/mSphere.00771-19

2020
Organogel Nanoparticles as a New Way to Improve Oral Bioavailability of Poorly Soluble Compounds

Baptiste Martin, Ghislain Garrait, Eric Beyssac, Dominique Goudounèche, Emile Perez, Sophie Franceschi-Messant

Pharmaceutical Research 37 (2020)10.1007/s11095-020-02808-w

2020
In silico molecular target prediction unveils mebendazole as a potent MAPK14 inhibitor

Jeremy Ariey‐bonnet, Kendall Carrasco, Marion Le Grand, Laurent Hoffer, Stéphane Betzi, Mikael Feracci, Philipp A Tsvetkov, François Devred, Yves Collette, Xavier Morelli, Pedro Ballester, Eddy Pasquier

Molecular Oncology 14:3083-3099 (2020)10.1002/1878-0261.12810

2020
The C-Terminal Domain of the Sudan Ebolavirus L Protein Is Essential for RNA Binding and Methylation

Coralie Valle, Baptiste Martin, Francoise Debart, Jean-Jacques Vasseur, Isabelle Imbert, Bruno Canard, Bruno Coutard, Etienne Decroly

Journal of Virology 94:e00520-20 (2020)10.1128/JVI.00520-20

2020
Fungal ecological strategies reflected in gene transcription ‐ a case study of two litter decomposers

Florian Barbi, Annegret Kohler, Kerrie Barry, Preetisri Baskaran, Chris Daum, Laure Fauchery, Katarina Ihrmark, Alan Kuo, Kurt Labutti, Anna Lipzen, Emmanuelle Morin, Igor Grigoriev, Bernard Henrissat, Björn Lindahl, Francis Martin

Environmental Microbiology 22:1089-1103 (2020)10.1111/1462-2920.14873

2020
Screening of five marine-derived fungal strains for their potential to produce oxidases with laccase activities suitable for biotechnological applications

Wissal Ben Ali, Delphine Chaduli, David Navarro, Christian Lechat, Annick Turbé-Doan, Emmanuel Bertrand, Craig B Faulds, Giuliano Sciara, Laurence Lesage-Meessen, Eric Record, Tahar Mechichi

BMC Biotechnology 20:27 (2020)10.1186/s12896-020-00617-y

2020
2020
At the nexus of three kingdoms: the genome of the mycorrhizal fungus Gigaspora margarita provides insights into plant, endobacterial and fungal interactions

Francesco Venice, Stefano Ghignone, Alessandra Salvioli Di Fossalunga, Joelle Amselem, Mara Novero, Xie Xianan, Kinga Sędzielewska Toro, Emmanuelle Morin, Anna Lipzen, Igor V. Grigoriev, Bernard Henrissat, Francis M. Martin, Paola Bonfante

Environmental Microbiology 22:122-141 (2020)10.1111/1462-2920.14827