2021

2021
Structure-function analysis of the nsp14 N7-guanine methyltransferase reveals an essential role in Betacoronavirus replication

Natacha S Ogando, Priscila El Kazzi, Jessika C Zevenhoven-Dobbe, Brenda W Bontes, Alice Decombe, Clara C S Posthuma, Volker Thiel, Bruno Canard, Francois Ferron, Etienne Decroly, Eric J Snijder

Proceedings of the National Academy of Sciences of the United States of America (2021)10.1101/2021.05.17.444407

2021
Genetic determinants of endophytism in the Arabidopsis root mycobiome

Fantin Mesny, Shingo Miyauchi, Thorsten Thiergart, Brigitte Pickel, Lea Atanasova, Magnus Karlsson, Bruno Hüttel, Kerrie Barry, Sajeet Haridas, Cindy Chen, Diane Bauer, William Andreopoulos, Jasmyn Pangilinan, Kurt Labutti, Robert Riley, Anna Lipzen, Alicia Clum, Elodie Drula, Bernard Henrissat, Annegret Kohler, Igor Grigoriev, Francis Martin, Stéphane Hacquard

Nature Communications 12:7227 (2021)10.1038/s41467-021-27479-y

2021
Clinical evidence of the role of Methanobrevibacter smithii in severe acute malnutrition

Aminata Camara, Salimata Konate, Maryam Tidjani Alou, Aly Kodio, Amadou Hamidou Togo, Sebastien Cortaredona, Bernard Henrissat, Mahamadou Ali Thera, Ogobara Doumbo, Didier Raoult, Matthieu Million

Scientific Reports 11 (2021)10.1038/s41598-021-84641-8

2021
Polysaccharide utilization loci-driven enzyme discovery reveals BD-FAE: a bifunctional feruloyl and acetyl xylan esterase active on complex natural xylans

Lisanne Hameleers, Leena Penttinen, Martina Ikonen, Léa Jaillot, Régis Fauré, Nicolas Terrapon, Peter J Deuss, Nina Hakulinen, Emma R Master, Edita Jurak

Biotechnology for Biofuels 14 (2021)10.1186/s13068-021-01976-0

2021
Discovery of fungal oligosaccharide-oxidising flavo-enzymes with previously unknown substrates, redox-activity profiles and interplay with LPMOs

Majid Haddad Momeni, Folmer Fredslund, Bastien Bissaro, Olanrewaju Raji, Thu Vuong, Sebastian Meier, Tine Sofie Nielsen, Vincent Lombard, Bruno Guigliarelli, Frédéric Biaso, Mireille Haon, Sacha Grisel, Bernard Henrissat, Ditte Hededam Welner, Emma Master, Jean-Guy Berrin, Maher Abou Hachem

Nature Communications 12 (2021)10.1038/s41467-021-22372-0

2021
Co‑cultivation of the anaerobic fungus Caecomyces churrovis with Methanobacterium bryantii enhances transcription of carbohydrate binding modules, dockerins, and pyruvate formate lyases on specific substrates

Jennifer Brown, Candice Swift, Stephen Mondo, Susanna Seppala, Asaf Salamov, Vasanth Singan, Bernard Henrissat, Elodie Drula, John Henske, Samantha Lee, Kurt Labutti, Guifen He, Mi Yan, Kerrie Barry, Igor Grigoriev, Michelle O'Malley

Biotechnology for Biofuels 14:234 (2021)10.1186/s13068-021-02083-w

2021
Display of the human mucinome with defined O-glycans by gene engineered cells

Rebecca Nason, Christian Büll, Andriana Konstantinidi, Lingbo Sun, Zilu Ye, Adnan Halim, Wenjuan Du, Daniel Sørensen, Fabien Durbesson, Sanae Furukawa, Ulla Mandel, Hiren Joshi, Leo Alexander Dworkin, Lars Hansen, Leonor David, Tina Iverson, Barbara Bensing, Paul Sullam, Ajit Varki, Erik De Vries, Cornelis de Haan, Renaud Vincentelli, Bernard Henrissat, Sergey Vakhrushev, Henrik Clausen, Yoshiki Narimatsu

Nature Communications 12:4070 (2021)10.1038/s41467-021-24366-4

2021
Ecological generalism drives hyperdiversity of secondary metabolite gene clusters in xylarialean endophytes

Mario Franco, Jennifer Wisecaver, a Elizabeth Arnold, Yu-Ming Ju, Jason Slot, Steven Ahrendt, Lillian Moore, Katharine Eastman, Kelsey Scott, Zachary Konkel, Stephen Mondo, Alan Kuo, Richard Hayes, Sajeet Haridas, Bill Andreopoulos, Robert Riley, Kurt Labutti, Jasmyn Pangilinan, Anna Lipzen, Mojgan Amirebrahimi, Juying Yan, Catherine Adam, Keykhosrow Keymanesh, Vivian Ng, Katherine Louie, Trent Northen, Elodie Drula, Bernard Henrissat, Huei-Mei Hsieh, Ken Youens-Clark, François Lutzoni, Jolanta Miadlikowska, Daniel Eastwood, Richard Hamelin, Igor Grigoriev, Jana U'Ren, A. Elizabeth Arnold, Yu‐ming Ju, Huei‐mei Hsieh, Ken Youens‐clark, Jana U’ren

New Phytologist (2021)10.1111/nph.17873

2021
System-oriented optimization of multi-target 2,6-diaminopurine derivatives: Easily accessible broad-spectrum antivirals active against flaviviruses, influenza virus and SARS-CoV-2

Ilaria Vicenti, Maria Grazia Martina, Adele Boccuto, Marta de Angelis, Giorgia Giavarini, Filippo Dragoni, Serena Marchi, Claudia Maria Trombetta, Emmanuele Crespan, Giovanni Maga, Cecilia Eydoux, Etienne Decroly, Emanuele Montomoli, Lucia Nencioni, Maurizio Zazzi, Marco Radi

European Journal of Medicinal Chemistry 224:113683 (2021)10.1016/j.ejmech.2021.113683

2021
System-oriented optimization of multi-target 2,6-diaminopurine derivatives: Easily accessible broad-spectrum antivirals active against flaviviruses, influenza virus and SARS-CoV-2

Ilaria Vicenti, Maria Grazia Martina, Adele Boccuto, Marta de Angelis, Giorgia Giavarini, Filippo Dragoni, Serena Marchi, Claudia Maria Trombetta, Emmanuele Crespan, Giovanni Maga, Cecilia Eydoux, Etienne Decroly, Emanuele Montomoli, Lucia Nencioni, Maurizio Zazzi, Marco Radi

European Journal of Medicinal Chemistry 224:113683 (2021)10.1016/j.ejmech.2021.113683

2021
Endonuclease-based genotyping of the RBM as a method to track the emergence or evolution of SARS-CoV-2 variants

Eva Lopez, Margot Barthélémy, Cécile Baronti, Shirley Masse, Alessandra Falchi, Fabien Durbesson, Renaud Vincentelli, Xavier de Lamballerie, Rémi Charrel, Bruno Coutard

iScience 24:103329 (2021)10.1016/j.isci.2021.103329

2021
Identification of copper-containing oxidoreductases in the secretomes of three Colletotrichum species with a focus on copper radical oxidases for the biocatalytic production of fatty aldehydes

David Ribeaucourt, Safwan Saker, David Navarro, Bastien Bissaro, Elodie Drula, Lydie Oliveira Correia, Mireille Haon, Sacha Grisel, Nicolas Lapalu, Bernard Henrissat, Richard J O’connell, Fanny Lambert, Mickaël Lafond, Jean-Guy Berrin

Applied and Environmental Microbiology 87:e01526-21 (2021)10.1128/AEM.01526-21

2021
Ty1 integrase is composed of an active N-terminal domain and a large disordered C-terminal module dispensable for its activity $in\ vitro$

Phong Quoc Nguyen, Christine Conesa, Elise Rabut, Gabriel Bragagnolo, Célia Gouzerh, Carlos Fernández-Tornero, Pascale Lesage, Juan Reguera, Joël Acker

Journal of Biological Chemistry 297:101093 (2021)10.1016/j.jbc.2021.101093

2021
Ty1 integrase is composed of an active N-terminal domain and a large disordered C-terminal module dispensable for its activity in vitro

Phong Quoc Nguyen, Christine Conesa, Elise Rabut, Gabriel Bragagnolo, Célia Gouzerh, Carlos Fernández-Tornero, Pascale Lesage, Juan Reguera, Joël Acker

Journal of Biological Chemistry 297:101093 (2021)10.1016/j.jbc.2021.101093

2021
Larvae of longhorned beetles (Coleoptera; Cerambycidae) have evolved a diverse and phylogenetically conserved array of plant cell wall degrading enzymes

Na Ra Shin, Seunggwan Shin, Yu Okamura, Roy Kirsch, Vincent Lombard, Petr Svacha, Olivier Denux, Sylvie Augustin, Bernard Henrissat, Duane Mckenna, Yannick Pauchet

Systematic Entomology 46:784-797 (2021)10.1111/syen.12488

2021
OntoRepliCov: an Ontology-Based Approach for Modeling the SARS-CoV-2 Replication Process

Wissame Laddada, Lina Soualmia, Cecilia Zanni-Merk, Ali Ayadi, Claudia Frydman, India L’hote, Isabelle Imbert

Procedia Computer Science 192:487-496 (2021)10.1016/j.procs.2021.08.050

2021
Symbiotic nitrogen fixation in the reproductive structures of a basidiomycete fungus

Rachel Koch, Gyeong Mee Yoon, Uma Aryal, Kathleen Lail, Mojgan Amirebrahimi, Kurt Labutti, Anna Lipzen, Robert Riley, Kerrie Barry, Bernard Henrissat, Igor Grigoriev, Joshua Herr, M Catherine Aime, M. Catherine Aime

Current Biology - CB 31:3905-3914.e6 (2021)10.1016/j.cub.2021.06.033

2021
An appeal for an objective, open, and transparent scientific debate about the origin of SARS-CoV-2

Jacques van Helden, Colin Butler, Guillaume Achaz, Bruno Canard, Didier Casane, Jean-Michel Claverie, Fabien Colombo, Virginie Courtier-Orgogozo, Richard Ebright, François Graner, Milton Leitenberg, Serge Morand, Nikolai Petrovsky, Rossana Segreto, Etienne Decroly, José Halloy

The Lancet 398:1402-1404 (2021)10.1016/S0140-6736(21)02019-5

2021
Identification of a Region in the Common Amino-terminal Domain of Hendra Virus P, V, and W Proteins Responsible for Phase Transition and Amyloid Formation

Edoardo Salladini, Frank Gondelaud, Juliet Nilsson, Giulia Pesce, Christophe Bignon, Maria Grazia Murrali, Roxane Fabre, Roberta Pierattelli, Andrey Kajava, Branka Horvat, Denis Gerlier, Cyrille Mathieu, Sonia Longhi

Biomolecules 11:1324 (2021)10.3390/biom11091324

2021
Secreted pectin monooxygenases drive plant infection by pathogenic oomycetes

Bernard Henrissat, Federico Sabbadin, Saioa Urresti, Anna Avrova, Lydia Welsh, Peter Lindley, Michael Csukai, Julie Squires, Paul Walton, Gideon Davies, Neil Bruce, Stephen Whisson, Simon Mcqueen-Mason

Science 373:774-779 (2021)10.1126/science.abj1342

2021
C -type cytochrome-initiated reduction of bacterial lytic polysaccharide monooxygenases

Jessie Branch, Badri Rajagopal, Alessandro Paradisi, Nick Yates, Peter Lindley, Jake Smith, Kristian Hollingsworth, W Bruce Turnbull, Bernard Henrissat, Alison Parkin, Alan Berry, Glyn Hemsworth, W. Bruce Turnbull

Biochemical Journal 478:2927-2944 (2021)10.1042/BCJ20210376

2021
Structure and Sequence Requirements for RNA Capping at the Venezuelan Equine Encephalitis Virus RNA 5′ End

Oney Ortega Granda, Coralie Valle, Ashleigh Shannon, Etienne Decroly, Bruno Canard, Bruno Coutard, Nadia Rabah

Journal of Virology 95 (2021)10.1128/JVI.00777-21

2021
Insights into animal septins using recombinant human septin octamers with distinct SEPT9 isoforms

Francois Iv, Carla Silva Martins, Gerard Castro-Linares, Cyntia Taveneau, Pascale Barbier, Pascal Verdier-Pinard, Luc Camoin, Stéphane Audebert, Feng-Ching Tsai, Laurie Ramond, Alex Llewellyn, Mayssa Belhabib, Koyomi Nakazawa, Aurelie Di Cicco, Renaud Vincentelli, Jérôme Wenger, Stéphanie Cabantous, Gijsje Koenderink, Aurélie Bertin, Manos Mavrakis, Carla Silva Martins

Journal of Cell Science 134:jcs258484 (2021)10.1242/jcs.258484

2021
Anchoring the T6SS to the cell wall: Crystal structure of the peptidoglycan binding domain of the TagL accessory protein

van Son Nguyen, Silvia Spinelli, E. Cascales, Alain Roussel, Christian Cambillau, Philippe Leone

PLoS ONE 16:e0254232 (2021)10.1371/journal.pone.0254232

2021
Anchoring the T6SS to the Cell Wall: Crystal Structure of the Peptidoglycan Binding Domain of the TagL Accessory Protein

Van Son Nguyen, Silvia Spinelli, Éric Cascales, Alain Roussel, Christian Cambillau, Philippe Leone

PLoS ONE (2021)

2021
Anchoring the T6SS to the cell wall: Crystal structure of the peptidoglycan binding domain of the TagL accessory protein

van Son Nguyen, Silvia Spinelli, E. Cascales, Alain Roussel, Christian Cambillau, Philippe Leone

PLoS ONE 16:e0254232 (2021)10.1371/journal.pone.0254232

2021
Evaluating microbiome-directed fibre snacks in gnotobiotic mice and humans

Omar Delannoy-Bruno, Chandani Desai, Arjun Raman, Robert Chen, Matthew Hibberd, Jiye Cheng, Nathan Han, Juan Castillo, Garret Couture, Carlito Lebrilla, Ruteja Barve, Vincent Lombard, Bernard Henrissat, Semen Leyn, Dmitry Rodionov, Andrei Osterman, David Hayashi, Alexandra Meynier, Sophie Vinoy, Kyleigh Kirbach, Tara Wilmot, Andrew Heath, Samuel Klein, Michael Barratt, Jeffrey Gordon

Nature 595:91-95 (2021)10.1038/s41586-021-03671-4

2021
A new non-classical fold of varroa odorant-binding proteins reveals a wide open internal cavity

Beatrice Amigues, Jiao Zhu, Anais Gaubert, Giovanni Renzone, Philippe Leone, Simona Arena, Isabella Maria Fischer, Harald Paulsen, Wolfgang Knoll, Andrea Scaloni, Alain Roussel, Christian Cambillau, Paolo Pelosi

Scientific Reports (2021)

2021
The enzymes for genome size increase and maintenance of large (+)RNA viruses

Francois Ferron, Bhawna Sama, Etienne Decroly, Bruno Canard

Trends in Biochemical Sciences (2021)10.1016/j.tibs.2021.05.006

2021
Structural Insights into the Mechanisms of Action of Functionally Distinct Classes of Chikungunya Virus Nonstructural Protein 1 Inhibitors

Kristina Kovacikova, Marina Gorostiola González, Rhian Jones, Juan Reguera, Alba Gigante, María-Jesús Pérez-Pérez, Gerhard Pürstinger, Julia Moesslacher, Thierry Langer, Lak Shin Jeong, Leen Delang, Johan Neyts, Eric Snijder, Gerard van Westen, Martijn van Hemert

Antimicrobial Agents and Chemotherapy 65 (2021)10.1128/AAC.02566-20

2021
Crystal structures of two camelid nanobodies raised against GldL, a component of the Type IX Secretion System from Flavobacterium johnsoniae

Thi Trang Nhung, Anaïs Gaubert, Pauline Melani, Christian Cambillau, Alain Roussel, Philippe Leone

Acta crystallographica Section F : Structural biology communications [2014-...] (2021)

2021
Community-Wide Experimental Evaluation of the PROSS Stability-Design Method

Yoav Peleg, Renaud Vincentelli, Brett M Collins, Kai-En Chen, Emma K Livingstone, Saroja Weeratunga, Natalya Leneva, Qian Guo, Kim Remans, Kathryn Perez, Gro E.K Bjerga, Øivind Larsen, Ondřej Vaněk, Ondřej Skořepa, A. Poterszman, Sophie Jacquemin, Svend Kjaer, Evangelos Christodoulou, Shira Albeck, Orly Dym, Elena Ainbinder, Tamar Unger, Anja Schuetz, Susann Matthes, Michael Bader, Ario de Marco, Paola Storici, Marta S Semrau, Peggy Stolt-Bergner, Christian Aigner, Sabine Suppmann, Adi Goldenzweig, Sarel J Fleishman

Journal of Molecular Biology 433:166964 (2021)10.1016/j.jmb.2021.166964

2021
Simeprevir Potently Suppresses SARS-CoV-2 Replication and Synergizes with Remdesivir

Ho Sing Lo, Kenrie Pui yan Hui, Hei-Ming Lai, Xu He, Khadija Shahed Khan, Simranjeet Kaur, Junzhe Huang, Zhongqi Li, Anthony Chan, Hayley Hei-yin Cheung, Ka-Chun Ng, John Chi Wang Ho, yu Wai Chen, Bowen Ma, Peter Man-Hin Cheung, Donghyuk Shin, Kaidao Wang, Meng-Hsuan Lee, Barbara Selisko, Cecilia Eydoux, Jean-Claude Guillemot, Bruno Canard, Kuen-Phon Wu, Po-Huang Liang, Ivan Dikic, Zhong Zuo, Francis Chan, David Hui, Vincent Mok, Kam-Bo Wong, Chris Ka Pun Mok, Ho Ko, Wei Shen Aik, Michael Chi Wai Chan, Wai-Lung Ng

ACS Central Science 7:792-802 (2021)10.1021/acscentsci.0c01186

2021
Gut microbiome contributions to altered metabolism in a pig model of undernutrition

Hao-Wei Chang, Nathan Mcnulty, Matthew Hibberd, David O'Donnell, Jiye Cheng, Vincent Lombard, Bernard Henrissat, Olga Ilkayeva, Michael Muehlbauer, Christopher Newgard, Michael Barratt, Xi Lin, Jack Odle, Jeffrey Gordon, David O’donnell

Proceedings of the National Academy of Sciences of the United States of America 118:e2024446118 (2021)10.1073/pnas.2024446118

2021
The methyltransferase domain of the Respiratory Syncytial Virus L protein catalyzes cap N7 and 2’-O-methylation

Priscila Sutto-Ortiz, Sergey Tcherniuk, Nina Ysebaert, Pravien Abeywickrema, Mathieu Noël, Alice Decombe, Françoise Debart, Jean-Jacques Vasseur, Bruno Canard, Dirk Roymans, Peter Rigaux, Jean-François Eléouët, Etienne Decroly

PLoS Pathogens 17:e1009562 (2021)10.1371/journal.ppat.1009562

2021
Characterization of three bacterial glycoside hydrolase family 9 endoglucanases with different modular architectures isolated from a compost metagenome

Laure Aymé, Agnès Hébert, Bernard Henrissat, Vincent Lombard, Nathalie Franche, Stéphanie Perret, Etienne Jourdier, Senta Heiss-Blanquet

Biochimica et Biophysica Acta (BBA) - General Subjects 1865:129848 (2021)10.1016/j.bbagen.2021.129848

2021
Genome Features of Asaia sp. W12 Isolated from the Mosquito Anopheles stephensi Reveal Symbiotic Traits

Shicheng Chen, Ting Yu, Nicolas Terrapon, Bernard Henrissat, Edward D Walker

Genes 12:752 (2021)10.3390/genes12050752

2021
Host PDZ‐containing proteins targeted by SARS‐CoV‐2

Célia Caillet-Saguy, Fabien Durbesson, Veronica Rezelj, Gergö Gogl, Quang Dinh Tran, Jean‐claude Twizere, Marco Vignuzzi, Renaud Vincentelli, Nicolas Wolff

FEBS Journal epub (2021)10.1111/febs.15881

2021
Macromolecular interactions in vitro, comparing classical and novel approaches

Christophe Velours, Magali Aumont-Nicaise, Stephan Uebel, Patrick England, Adrian Velazquez-Campoy, David Stroebel, Guillaume Bec, Pierre Soule, Christophe Quétard, Christine Ebel, Alain Roussel, Jean-Baptiste Charbonnier, Paloma Fernández Varela

European Biophysics Journal 50:313-330 (2021)10.1007/s00249-021-01517-5

2021
Strain-level functional variation in the human gut microbiota based on bacterial binding to artificial food particles

Michael Patnode, Janaki Guruge, Juan Castillo, Garret Couture, Vincent Lombard, Nicolas Terrapon, Bernard Henrissat, Carlito Lebrilla, Jeffrey Gordon

Cell Host & Microbe 29:664-673.e5 (2021)10.1016/j.chom.2021.01.007

2021
Tracing the origins of SARS-COV-2 in coronavirus phylogenies: a review

Erwan Sallard, José Halloy, Didier Casane, Etienne Decroly, Jacques van Helden

Environmental Chemistry Letters 19:769-785 (2021)10.1007/s10311-020-01151-1

2021
Characterization of the β-glucuronidase Pn3Pase as the founding member of glycoside hydrolase family GH169

Paeton Wantuch, Satya Jella, Jeremy Duke, Jarrod Mousa, Bernard Henrissat, John Glushka, Fikri Avci

Glycobiology 31:266-274 (2021)10.1093/glycob/cwaa070

2021
Gene family expansions and transcriptome signatures uncover fungal adaptations to wood decay

Hayat Hage, Shingo Miyauchi, Máté Virágh, Elodie Drula, Byoungnam Min, Delphine Chaduli, David Navarro, Anne Favel, Manon Norest, Laurence Lesage‐meessen, Balázs Bálint, Zsolt Merényi, Laura Eugenio, Emmanuelle Morin, Angel T Martínez, Petr Baldrian, Martina Štursová, María Jesús Martínez, Cenek Novotny, Jon K Magnuson, Joey W Spatafora, Sundy Maurice, Jasmyn Pangilinan, Willian Andreopoulos, Kurt Labutti, Hope Hundley, Hyunsoo Na, Alan Kuo, Kerrie Barry, Anna Lipzen, Bernard Henrissat, Robert Riley, Steven Ahrendt, László G Nagy, Igor V Grigoriev, Francis Martin, Marie‐noëlle Rosso

Environmental Microbiology (2021)10.1111/1462-2920.15423

2021
Comparative mapping of selected structural determinants on the extracellular domains of cholinesterase-like cell-adhesion molecules.

Davide Comoletti, Laura Trobiani, Arnaud Chatonnet, Yves Bourne, P. Marchot

Neuropharmacology 184:108381 (2021)10.1016/j.neuropharm.2020.108381

2021
A High-Affinity Peptide Ligand Targeting Syntenin Inhibits Glioblastoma

Linda Haugaard-Kedström, Louise Clemmensen, Vita Sereikaite, Zeyu Jin, Eduardo Fernandes, Bianca Wind, Flor Abalde-Gil, Jan Daberger, Maria Vistrup-Parry, Diana Aguilar-Morante, Raphael Leblanc, Antonio Egea-Jimenez, Marte Albrigtsen, Kamilla. Jensen, Thomas Jensen, Ylva Ivarsson, Renaud Vincentelli, Petra Hamerlik, Jeanette Hammer Andersen, Pascale Zimmermann, Weontae Lee, Kristian Strømgaard

Journal of Medicinal Chemistry 64:1423-1434 (2021)10.1021/acs.jmedchem.0c00382

2021
Observation of arenavirus nucleoprotein heptamer assembly

Nicolas Papageorgiou, Afroditi Vaitsopoulou, Awa Diop, Thi Hong van Nguyen, Bruno Canard, Karine Alvarez, Francois Ferron

FEBS Open Bio (2021)10.1002/2211-5463.13106

2021
Niche differentiation and evolution of the wood decay machinery in the invasive fungus Serpula lacrymans

Jaqueline Hess, Sudhagar Balasundaram, Renee Bakkemo, Elodie Drula, Bernard Henrissat, Nils Högberg, Daniel Eastwood, Inger Skrede

ISME Journal 15:592-604 (2021)10.1038/s41396-020-00799-5

2021
A fluorescence-based high throughput-screening assay for the SARS-CoV RNA synthesis complex

Cecilia Eydoux, Veronique Fattorini, Ashleigh Shannon, Thi-Tuyet-Nhung Le, Bruno Didier, Bruno Canard, Jean-Claude Guillemot

Journal of Virological Methods 288:114013 (2021)10.1016/j.jviromet.2020.114013

2021
Structural and dynamics analysis of intrinsically disordered proteins by high-speed atomic force microscopy

Noriyuki Kodera, Daisuke Noshiro, Sujit K Dora, Tetsuya Mori, Johnny Habchi, David Blocquel, Antoine Gruet, Marion Dosnon, Edoardo Salladini, Christophe Bignon, Yuko Fujioka, Takashi Oda, Nobuo N Noda, Mamoru Sato, Marina Lotti, Mineyuki Mizuguchi, Sonia Longhi, Toshio Ando

Nature Nanotechnology 16:181-189 (2021)10.1038/s41565-020-00798-9

2021
Dengue Virus NS5 Transcribes Metabolite-Capped, RIG-I Sensitive vRNAs

Brandon Schweibenz, Mihai Solotchi, Etienne Decroly, Barbara Selisko, Bruno Canard, Smita Patel

Biophysical Journal 120:135a (2021)10.1016/j.bpj.2020.11.1017

2021
Proteome specialization of anaerobic fungi during ruminal degradation of recalcitrant plant fiber

Live Hagen, Charles Brooke, Claire Shaw, Angela Norbeck, Hailan Piao, Magnus Ø. Arntzen, Heather E. Olson, Alex Copeland, Nancy Isern, Anil Shukla, Simon Roux, Vincent Lombard, Bernard Henrissat, Michelle O’malley, Igor Grigoriev, Susannah Tringe, Roderick Mackie, Ljiljana Pasa-Tolic, Phillip Pope, Matthias Hess

ISME Journal 15:421-434 (2021)10.1038/s41396-020-00769-x

2021
Evolutionary innovations through gain and loss of genes in the ectomycorrhizal Boletales

Gang Wu, Shingo Miyauchi, Emmanuelle Morin, Alan Kuo, Elodie Drula, Torda Varga, Annegret Kohler, Bang Feng, Yang Cao, Anna Lipzen, Christopher Daum, Hope Hundley, Jasmyn Pangilinan, Jenifer Johnson, Kerrie Barry, Kurt Labutti, Vivian Ng, Steven Ahrendt, Byoungnam Min, In‐geol Choi, Hongjae Park, Jonathan Plett, Jon Magnuson, Joseph Spatafora, László Nagy, Bernard Henrissat, Igor Grigoriev, Zhu‐liang Yang, Jianping Xu, Francis Martin

New Phytologist 10 (2021)10.1111/nph.17858

2021
COVID-19 epidemiologic surveillance using wastewater

Virender Sharma, Chetan Jinadatha, Eric Lichtfouse, Etienne Decroly, Jacques van Helden, Hosoon Choi, Piyali Chatterjee

Environmental Chemistry Letters 19:1911-1915 (2021)10.1007/s10311-021-01188-w

2021
Multimodularity of a GH10 Xylanase Found in the Termite Gut Metagenome

Haiyang Wu, Eleni Ioannou, Bernard Henrissat, Cédric Montanier, Sophie Bozonnet, Michael O'Donohue, Claire Dumon

Applied and Environmental Microbiology 87 (2021)10.1128/AEM.01714-20

2021
Lignin from oil palm empty fruit bunches: Characterization, biological activities and application in green synthesis of silver nanoparticles

Luis Alberto Zevallos Torres, Adenise Lorenci Wociciechowski, Valcineide Oliveira de Andrade Tanobe, Arion Zandoná Filho, Rilton Alves de Freitas, Miguel Daniel Noseda, Erico Saito Szameitat, Craig Faulds, Pedro Coutinho, Emanuel Bertrand, Carlos Ricardo Soccol

International Journal of Biological Macromolecules (2021)10.1016/j.ijbiomac.2020.11.104

2021
Characterization of the first virulent phage infecting Oenococcus oeni, the queen of the cellars

Cécile Philippe, Amel Chaib, Fety Jaomanjaka, Olivier Claisse, Patrick Lucas, Johan Samot, Christian C. Cambillau, Claire Le Marrec

Frontiers in Microbiology 11:1-13 (2021)10.3389/fmicb.2020.596541

2021
Bioinformatic Analysis of Lytic Polysaccharide Monooxygenases Reveals the Pan-Families Occurrence of Intrinsically Disordered C-Terminal Extensions

Ketty C Tamburrini, Nicolas Terrapon, Vincent Lombard, Bastien Bissaro, Sonia Longhi, Jean-Guy Berrin

Biomolecules 11:1632 (2021)10.3390/biom11111632

2021
Identification of the molecular determinants driving the substrate specificity of fungal lytic polysaccharide monooxygenases (LPMOs)

Kristian E.H. Frandsen, Kristian Frandsen, Mireille Haon, Sacha Grisel, Bernard Henrissat, Leila Lo Leggio, Jean-Guy Berrin

Journal of Biological Chemistry 296:100086 (2021)10.1074/jbc.RA120.015545

2021
The methyltransferase domain of the Respiratory Syncytial Virus L protein catalyzes cap N7 and 2’-O-methylation

Priscila Sutto-Ortiz, Sergey Tcherniuk, Nina Ysebaert, Pravien Abeywickrema, Mathieu Noël, Alice Decombe, Françoise Debart, Jean-Jacques Vasseur, Bruno Canard, Dirk Roymans, Peter Rigaux, Jean-François Eléouët, Etienne Decroly

PLoS Pathogens 17:1-20 (2021)10.1371/journal.ppat.1009562

2021
Comprehensive Intrinsic Disorder Analysis of 6108 Viral Proteomes: From the Extent of Intrinsic Disorder Penetrance to Functional Annotation of Disordered Viral Proteins

Naveen Kumar, Rahul Kaushik, Chandana Tennakoon, Vladimir N Uversky, Sonia Longhi, Kam y J Zhang, Sandeep Bhatia

Journal of Proteome Research 20:2704-2713 (2021)10.1021/acs.jproteome.1c00011

2021
Functional diversity of three tandem C-terminal carbohydrate-binding modules of a β-mannanase

Marie Sofie Møller, Souad El Bouaballati, Bernard Henrissat, Birte Svensson

Journal of Biological Chemistry 296:100638 (2021)10.1016/j.jbc.2021.100638

2021
Preanalytical issues and cycle threshold values in SARS-CoV-2 real-time RT-PCR testing: should test results include these?

Ilka Engelmann, Enagnon Kazali Alidjinou, Judith Ogiez, Quentin Pagneux, Sana Miloudi, Ilyes Benhalima, Mahdi Ouafi, Famara Sané, Didier Hober, Alain Roussel, Christian Cambillau, David Devos, Rabah Boukherroub, Sabine Szunerits

ACS Omega 6:6528-6536 (2021)10.1021/acsomega.1c00166

2021
The WHO mission report struggles to trace the origins of the SARS-CoV-2 epidemic

Etienne Decroly, Jean-Michel Claverie, Bruno Canard

Virologie 1-7 (2021)

2021
OntoRepliCov: an Ontology-Based Approach for Modeling the SARS-CoV-2 Replication Process

Wissame Laddada, Lina Soualmia, Cecilia Zanni-Merk, Ali Ayadi, Claudia Frydman, India L’hote, Isabelle Imbert

Procedia Computer Science 192:487-496 (2021)10.1016/j.procs.2021.08.050

2021
Combining Antivirals and Immunomodulators to Fight COVID-19

Vincent Feuillet, Bruno Canard, Alain Trautmann

Trends in Immunology 42:31-44 (2021)10.1016/j.it.2020.11.003

2021
First insights into the structural features of Ebola virus methyltransferase activities

Coralie Valle, Baptiste Martin, François Ferron, Véronique Roig-Zamboni, Aline Desmyter, Françoise Debart, Jean Jacques Vasseur, Bruno Canard, Bruno Coutard, Etienne Decroly

Nucleic Acids Research 49:1737-1748 (2021)10.1093/nar/gkaa1276

2021
Identification of Copper-Containing Oxidoreductases in the Secretomes of Three Colletotrichum Species with a Focus on Copper Radical Oxidases for the Biocatalytic Production of Fatty Aldehydes

David Ribeaucourt, Safwan Saker, David Navarro, Bastien Bissaro, Elodie Drula, Lydie Oliveira Correia, Mireille Haon, Sacha Grisel, Nicolas Lapalu, Bernard Henrissat, Richard O’connell, Fanny Lambert, Mickaël Lafond, Jean-Guy Berrin

Applied and Environmental Microbiology 87:e01526-21 (2021)10.1128/AEM.01526-21

2021
Carnitine is a pharmacological allosteric chaperone of the human lysosomal α -glucosidase

Roberta Iacono, Nadia Minopoli, Maria Carmina Ferrara, Antonietta Tarallo, Carla Damiano, Caterina Porto, Sandra Strollo, Véronique Roig-Zamboni, Gianfranco Peluso, Gerlind Sulzenbacher, Beatrice Cobucci-Ponzano, Giancarlo Parenti, Marco Moracci

Journal of Enzyme Inhibition and Medicinal Chemistry 36:2068-2079 (2021)10.1080/14756366.2021.1975694